Soportes epigráficos de los Orgenomescos

Se presenta un ensayo multidisciplinar con el que se pretende arrojar luz sobre la epigrafía cántabra, mediante la recopilación y estudio, en este caso, de las inscripciones del pueblo de los orgenomescos. El principal objetivo de este trabajo es el análisis de los soportes epigráficos utilizados por los indígenas y su evolución durante la dominación romana mediante el análisis de las 16 inscripciones conocidas, halladas en las actuales provincias de Cantabria, Asturias, Palencia y Jaén. Se distingue una sociedad indígena mixta que presenta un mestizaje entre el mundo prerromano y romano con fuertes pervivencias en sus tradiciones, resultado de un proceso de aculturación e integración onomástica y social.This multidisciplinary essay aims to shed light on the Cantabrian epigraphy, by collecting and studying, in this case, the Orgenomesci people. The main goal of this research are the epigraphic supports used by the natives and their evolution during the roman dominion, by the study of the 16 epigraphic steles and inscriptions found in the actual provinces of Cantabria, Asturias, Palencia and Jaén. Hence, we can perceive a mixted native society with miscegenation between the preroman and roman world, alongside the survival of strong traditions, consequence of an acculturization process, onomastic and social integration

MARCO GENERAL DE LA GESTIÓN ORGANIZACIONAL DE LAS PEQUEÑAS Y MEDIANAS EMPRESAS (PYMES): INCENTIVOS INSTITUCIONALES Y PALIATIVOS DEL MERCADO

La tendencia a formalizar el comportamiento empresarial a través de la definición de modelos de gestión organizacional en las PyMEs, implica analizar la estructura y fundamentación ex ante en que estos son basados. El análisis que debe rodear la constitución de un modelo, está siendo reducido por argumentos apriorísticos y evaluaciones dependientes del mecanismo, bajo el cual los datos y la información son obtenidos. El análisis sobre la estructuración de modelos debe guardar correspondencia desde las bases estadísticas, matemáticas y de programación sin distingo de alcance metodológico, que constituye el acervo del modelo y que en esencia no es visible. La modelación en cualquier escenario, requiere el trato propio al respecto y no una presentación semántica con la que se trata de ligar una idea

Interpersonal Violence and Psychotic-Like Experiences: The Mediation of Ideas of Reference, Childhood Memories, and Dissociation

Previous studies have demonstrated the relationship between the accumulation of situations involving interpersonal violence (IV) and psychotic-like experiences. This study explored whether IV is related to aberrant salience (AS), using a sequential mediation model that included memories of relationship with parents (submission, devaluation, and threat; Early Life Experiences Scale (ELES)), ideas of reference (IR), and dissociative symptoms (absorption and depersonalization), and whether the patient/nonpatient condition moderated this effect. The sample was made of 401 participants (including 43 patients with psychotic disorders) aged 18 to 71 years (Mage = 30.43;SD= 11.19). Analysis of a serial multiple mediator model revealed that IR, ELES, absorption, and depersonalization fully mediated the effect of IV on AS, explaining 39% of the variance, regardless of the patient/nonpatient condition. The indirect paths, which place IR and dissociation (especially absorption, the variable to which the IR and ELES lead) in a primordial position for being related to AS, are discussed. This continuum model could be useful for understanding processes related to the onset of psychosis unmoderated by the patient/nonpatient condition

Coumarin: a novel player in microbial quorum sensing and biofilm formation inhibition

Antibiotic resistance is a growing threat worldwide, causing serious problems in the treatment of microbial infections. The discovery and development of new drugs is urgently needed to overcome this problem which has greatly undermined the clinical effectiveness of conventional antibiotics. An intricate cell-cell communication system termed quorum sensing (QS) and the coordinated multicellular behaviour of biofilm formation have both been identified as promising targets for the treatment and clinical management of microbial infections. QS systems allow bacteria to adapt rapidly to harsh conditions, and are known to promote the formation of antibiotic tolerant biofilm communities. It is well known that biofilm is a recalcitrant mode of growth and it also increases bacterial resistance to conventional antibiotics. The pharmacological properties of coumarins have been well described, and these have included several that possess antimicrobial properties. More recently, reports have highlighted the potential role of coumarins as alternative therapeutic strategies based on their ability to block the QS signalling systems and to inhibit the formation of biofilms in clinically relevant pathogens. In addition to human infections, coumarins have also been found to be effective in controlling plant pathogens, infections in aquaculture, food spoilage and in reducing biofouling caused by eukaryotic organisms. Thus, the coumarin class of small molecule natural product are emerging as a promising strategy to combat bacterial infections in the new era of antimicrobial resistance

Stock assessment diagnostics for South Atlantic swordfish

Catch and catch per unit effort are used to fit a biomass dynamic stock assessment model. A variety of diagnostics are then used to check for violations of model assumptions and to explore the information in the data. Potential problems are identified and ways to overcome or avoid them discussed.Versión del edito

Kobe II strategy matrices for North Atlantic swordfish based on catch, fishing mortality and harvest control rules.

Scientific stock assessment advice given by the SCRS is presented in the form of the Kobe II Strategy Matrix (K2SM). Traditionally the K2SM shows the probabilities by year for different catches of achieving the management objective of ensuring that the stock biomass is greater than BMSY and fishing mortality less than FMSY. However, a K2SM can also be used, as in this paper, to help guide discussion about choice of reference points for use as part of a Harvest Control Rule.Versión del edito

Stock assessment diagnostics for North Atlantic swordfish

Catch and catch per unit effort are used to fit a biomass dynamic stock assessment model. A variety of diagnostics are then used to check for violations of model assumptions and to explore the information in the data. Potential problems are identified and ways to overcome or avoid them discussed.Versión del edito

Implementation of a harvest control rule for northern Atlantic albacore

A Harvest Control Rule was developed for North Atlantic albacore during the 2013 assessment, this paper documents the procedure used.Versión del edito

Model-driven in reverse. The practical experience of the AQUA project

Model-Driven Web Engineering (MDWE) is a new paradigm which provides satisfactory results in software development. However, most experiments with MDWE towards the development of software from the requirements to the implementation stages. However, in practice, sometimes software development does not follow this classic path. In this paper, MDWE is presented as a suitable selection in software projects of technological evolution. The AQUA project is a very large and important project which is a fusion of three previous systems. Thus, this project starts with the original code of these three systems. The paper introduces the power of MDWE in this kind of systems.Ministerio de Educación y Ciencia TIN2007-67843-C06_03Ministerio de Educación y Ciencia IN2007-30391-

Multi-GPU Development of a Neural Networks Based Reconstructor for Adaptive Optics

Aberrations introduced by the atmospheric turbulence in large telescopes are compensated using adaptive optics systems, where the use of deformable mirrors and multiple sensors relies on complex control systems. Recently, the development of larger scales of telescopes as the E-ELT or TMT has created a computational challenge due to the increasing complexity of the new adaptive optics systems. The Complex Atmospheric Reconstructor based on Machine Learning (CARMEN) is an algorithm based on artificial neural networks, designed to compensate the atmospheric turbulence. During recent years, the use of GPUs has been proved to be a great solution to speed up the learning process of neural networks, and different frameworks have been created to ease their development. The implementation of CARMEN in different Multi-GPU frameworks is presented in this paper, along with its development in a language originally developed for GPU, like CUDA. This implementation offers the best response for all the presented cases, although its advantage of using more than one GPU occurs only in large networks