Photobiomodulation reduces inflammation but does not influence the hypoxia-inducible factor-1α in pulp tissue of rats after bleaching

Objectives: To evaluate the influence of photobiomodulation with infrared laser (IRL) in the rat pulp tissue after bleaching, considering the immunolabeling of interleukin (IL)-23 and hypoxia-inducible factor (HIF)-1α. Methodology: The right and left molars of forty rats were divided into groups: Control – with placebo gel and Bleached – with 35% hydrogen peroxide (H2O2). Half of the rats received one IRL application on both sides, establishing a split-mouth design, which resulted in 4 groups with 20 hemi-maxillae each: Control, Bleach, IRL, and Bleached-IRL. Rats (n=10) from each group were euthanized, at 2- and 30-days mark, and the pulp tissue was evaluated using inflammation and immunolabeling scores. Wilcoxon and Mann-Whitney statistical tests were performed (p<0.05). Results: At the 2-days mark, the Bleached group had severe inflammation and necrosis in the occlusal thirds of the pulp, and moderate to severe inflammation in cervical third, whereas the Bleached-IRL had mild to moderate inflammation (p<0.05). At the 30-days mark, there was no inflammation, but tertiary dentine formation in the bleached groups. Regarding IL-23, severe immunolabeling was observed in the Bleached group (p<0.05) at the 2-days mark; at the 30-days mark, there was a reduction in immunolabeling, in which the Bleached group had moderate and the Bleached-IRL group had mild immunolabeling (p>0.05). HIF-1α was more evident at the 2-days mark in the Bleached group, without significant difference with the Bleached-IRL (p>0.05). The difference was observed between the bleached and control groups, without immunolabeling (p<0.05); at the 30-days mark, the Bleached group had reduction in HIF-1α immunolabeling, while the Bleached-IRL had an increase; the difference remained between the bleached and the controls groups (p<0.05). Conclusion: Photobiomodulation using IRL minimized the inflammation and IL-23 immunolabeling in the pulp tissue of rats after dental bleaching, but did not influence significantly the HIF-1α immunolabeling

Diagnosis oral by optical fluorescence image system.

A fluorescência óptica tem sido empregada em diferentes áreas médicas como também na Odontologia por apresentar elevada sensibilidade, simplicidade, sendo rápida na obtenção de dados. A avaliação por fluorescência não é invasiva e consiste em um grande benefício para o diagnóstico clínico. Nosso objetivo foi visualizar clinicamente pelo sistema de fluorescência óptica, as imagens dos quadros de normalidade e/ou alterações das estruturas dentárias e tecidos moles adjacentes. Com o sistema de fluorescência, foi possível verificar na cavidade bucal imagens não vistas a “olho nu”. Concluímos que este novo sistema de imagem por fluorescência óptica é simples de utilizar, rápido, seguro e serve como novo guia de diagnóstico bucal por imagem

Diagnosis oral by optical fluorescence image system.

A fluorescência óptica tem sido empregada em diferentes áreas médicas como também na Odontologia por apresentar elevada sensibilidade, simplicidade, sendo rápida na obtenção de dados. A avaliação por fluorescência não é invasiva e consiste em um grande benefício para o diagnóstico clínico. Nosso objetivo foi visualizar clinicamente pelo sistema de fluorescência óptica, as imagens dos quadros de normalidade e/ou alterações das estruturas dentárias e tecidos moles adjacentes. Com o sistema de fluorescência, foi possível verificar na cavidade bucal imagens não vistas a “olho nu”. Concluímos que este novo sistema de imagem por fluorescência óptica é simples de utilizar, rápido, seguro e serve como novo guia de diagnóstico bucal por imagem

Laser therapy on regenerative endodontic procedures: A scoping review

Endodontic treatment of teeth with incomplete root formation is a challenge. One of the treatment alternatives is the regenerative endodontic treatment, the formation of a blood clot inside the root canal occurs, which will work as a scaffold with the aim of enabling cell growth. Uses the concept of tissue engineering to restore root canals to a healthy state, allowing for continued development of the root and surrounding tissues. Several protocols have been proposed, without a consensus among authors. The objective of this scope review is to show the general panorama of the use of photodynamic therapies in regenerative endodontic treatment

Use of the CAPES Digital Library of Scientific Journals in the Graduate Studies Program at the School of Dentistry of Araraquara - UNESP - in the period from 2000 to 2005

Este artigo apresenta o resultado de uma pesquisa que teve por objetivo principal verificar se o Portal de Periódicos CAPES atende às necessidades de informação de usuários na área de odontologia. Como revisão de literatura, o trabalho traça a evolução, a consolidação e as tendências das bibliotecas digitais de periódicos e analisa as pesquisas existentes sobre o uso do Portal de Periódicos CAPES por usuários da área de saúde e ciências correlatas. O estudo identificou 91 títulos de periódicos de odontologia citados nas referências bibliográficas das teses e dissertações defendidas no período de 2000 a 2005, na Faculdade de Odontologia da UNESP de Araraquara, os quais foram comparados com aqueles que constam do Portal de Periódicos CAPES. Nos resultados são relacionados, para a área de odontologia, os títulos de periódicos citados mas não pertencentes ao Portal, os títulos do Portal não citados nos trabalhos e a frequência de citação de cada título. Essa análise propiciou, também, levantar dados sobre os periódicos de odontologia mais utilizados pelos alunos de pós-graduação da mesma faculdade, para verificar a adequação da coleção de periódicos da sua Biblioteca às necessidades de informação de seus usuários.This paper presents the results of a study that aimed at verifying if the contents of the CAPES Digital Library of Scientific Journals attend the information needs of users in the area of dentistry. In the literature review, the article traces the evolution, consolidation and trends of digital libraries of electronic journals and analyses the research about the use of the CAPES Digital Library by scholars in the health sciences and correlated areas. The study identified 91 journal titles cited in the bibliography references of the thesis and dissertations defended in the period from 2000 to 2005 at the School of Dentistry of Araraquara, Sao Paulo State University (UNESP) which were compared with those present in the CAPES Digital Library. The results show, for the area of dentistry, the periodicals which were cited but were not in the CAPES Digital Library, the periodicals which were in the CAPES Digital Library but were not cited and the number of times each title was cited. This analysis also gathered data about the journal titles which have the highest citation rates by the graduate students in order to verify the adequacy of the library journal collection to the information needs of the users

Conservative treatment of patients with periapical lesions associated with extraoral sinus tracts

This paper describes the clinical courses of three cases with extra-oral sinus tract formation, from diagnosis and treatment to short-term follow-up and evaluation. All teeth involved had periradicular radiolucent areas noted on radiographic examination and extra-oral sinus tracts appearing on the chin with exudation and unpleasant aesthetic appearance. The adopted treatment protocol included treating the sinus tract surface simultaneously with the root canal therapy. After root canal shaping using 5.25% sodium hypochlorite solution, calcium hydroxide-based pastes associated with different vehicles were inserted into the root canal for 4 months, and were changed monthly. All the sinus tracts healed in 7 to 10 days. The apical lesions were completely repaired in a maximum period of 24 months. The treatment adopted provided a complete healing of the periapical lesions in a short follow-up period. Surgical repair of the cutaneous sinus tract was therefore unnecessary. © 2007 The Authors. Journal compilation © 2007 Australian Society of Endodontology

Cyclic fatigue resistance of novel Genius and Edgefile nickel-titanium reciprocating instruments

Abstract: This study aimed to assess the cyclic fatigue resistance of Genius and EdgeFile X1 reciprocating instruments compared with WaveOne Gold Primary. Twenty Genius (Ultradent) 25.04, 20 Genius 30.04, 20 EdgeFile X1 (EdgeEndo) and 20 WaveOne Gold Primary (Dentsply Maillefer) instruments were included in this study and tested in a static cyclic fatigue testing device, which has an artificial stainless steel canal with a 60° angle of curvature and a 5-mm radius of curvature. All instruments were operated in reciprocation mode until fracture occurred. The number of cycles to failure (NCF) was calculated and time to fracture (TF) was recorded in seconds using a digital chronometer. The mean and standard deviations of NCF and TF were calculated for each reciprocating system and the data were subjected to Kruskal-Wallis one-way analysis of variance and to Dunn's test (p < .05) using SigmaPlot software (Systat software, CA, USA). The fractured surfaces of five instruments from each brand were randomly examined and microphotographed by a low-vacuum environmental scanning electron microscopy – SEM (Tabletop Microscope TM3030, Hitachi, Japan) to confirm the cyclic fatigue fracture. EdgeFile exhibited the highest cyclic fatigue resistance, followed by both Genius files (p < .05). Within the limitations of this in vitro study, EdgeFile X1 instruments had significantly higher cyclic fatigue resistance than did Genius and WaveOne Gold Primary instruments. The cyclic fatigue resistance of both Genius files was higher than that of WaveOne Gold Primary

Uso dos periódicos do Portal CAPES pelos Programas de Pós-graduação da Faculdade de Odontologia de Araraquara - UNESP - no período de 2000 a 2005

Este artigo apresenta o resultado de uma pesquisa que teve por objetivo principal verificar se o Portal de Periódicos CAPES atende às necessidades de informação de usuários na área de odontologia. Como revisão de literatura, o trabalho traça a evolução, a consolidação e as tendências das bibliotecas digitais de periódicos e analisa as pesquisas existentes sobre o uso do Portal de Periódicos CAPES por usuários da área de saúde e ciências correlatas. O estudo identificou 91 títulos de periódicos de odontologia citados nas referências bibliográficas das teses e dissertações defendidas no período de 2000 a 2005, na Faculdade de Odontologia da UNESP de Araraquara, os quais foram comparados com aqueles que constam do Portal de Periódicos CAPES. Nos resultados são relacionados, para a área de odontologia, os títulos de periódicos citados mas não pertencentes ao Portal, os títulos do Portal não citados nos trabalhos e a frequência de citação de cada título. Essa análise propiciou, também, levantar dados sobre os periódicos de odontologia mais utilizados pelos alunos de pós-graduação da mesma faculdade, para verificar a adequação da coleção de periódicos da sua Biblioteca às necessidades de informação de seus usuários

Diabetic Rats Present High Mean Platelet Count in the Presence of Oral Infections

<div><p>Abstract Platelet count is associated with inflammatory diseases like diabetes mellitus (DM), which in turn, is related in a bidirectional manner with apical periodontitis and periodontal disease. The aim of this study was to evaluate the effects of apical periodontitis and/or periodontal disease on mean platelet count in a rat model of diabetes mellitus. Eighty Wistar rats were randomly divided into 8 groups (n=10): control (C), apical periodontitis (AP), periodontal disease (PD), apical periodontitis with periodontal disease (AP-PD), diabetes mellitus (DM), diabetes mellitus with apical periodontitis (DM-AP), diabetes mellitus with periodontal disease (DM-PD) and diabetes mellitus with apical periodontitis and periodontal disease (DM-AP-PD). Rats were anesthetized and DM was induced with a single dose of streptozotocin diluted in citrate buffer solution. After 6 days, the DM was confirmed. The animals were sedated and apical periodontitis was induced by dental exposure and periodontal disease was induced by periodontal ligature. After 30 days, animals were anesthetized and the blood was collected by cardiac puncture. Samples were processed and the mean platelet count was obtained. Data were tabulated and subjected to statistical analysis (p<0.05). Diabetic rats had higher mean glycemic levels compared with nondiabetic rats at 6 and 36 days after DM induction (p<0.05). The DM-PD and DM-PD-AP groups showed increased mean platelet count compared to control and AP groups (p<0.05). The periodontal disease alone or associated with apical periodontitis influence mean platelet count in a rat model of diabetes mellitus.</p></div