DAMIC at SNOLAB

We introduce the fully-depleted charge-coupled device (CCD) as a particle detector. We demonstrate its low energy threshold operation, capable of detecting ionizing energy depositions in a single pixel down to 50 eVee. We present results of energy calibrations from 0.3 keVee to 60 keVee, showing that the CCD is a fully active detector with uniform energy response throughout the silicon target, good resolution (Fano ~0.16), and remarkable linear response to electron energy depositions. We show the capability of the CCD to localize the depth of particle interactions within the silicon target. We discuss the mode of operation and unique imaging capabilities of the CCD, and how they may be exploited to characterize and suppress backgrounds. We present the first results from the deployment of 250 um thick CCDs in SNOLAB, a prototype for the upcoming DAMIC100. DAMIC100 will have a target mass of 0.1 kg and should be able to directly test the CDMS-Si signal within a year of operation.Comment: 13 pages, 12 figures, proceedings prepared for 13th International Conference on Topics in Astroparticle and Underground Physics (TAUP2013

Twenty years of climate policy: G20 coverage and gaps

The number and coverage of climate change mitigation policies have increased in the past twenty years, but important policy adoption gaps remain. To analyse sectoral climate policy in the G20 over time (2000–2019), we compiled a dataset of climate change mitigation-relevant policies and identified 50 key policy options that constitute a comprehensive sectoral climate policy package. Approximately half of these policy options are not widely adopted. Adoption is particularly low for policies that aim to: phase out coal and oil and mandate energy reductions in electricity and heat supply; reduce industrial process emissions and incentivise fuel switch in industry; design urban planning strategies for retrofits; and support the use of renewable energy for cooking and heating/cooling purposes in buildings. Policies to remove fossil fuel subsidies and support carbon dioxide removal also need substantial improvement. However, many policy adoption gaps exist as the coverage of at least one policy option could be improved in each sector. Policy adoption gaps leave at least one-tenth of the G20’s emissions completely uncovered. Filling these gaps is fundamental to realize the full mitigation potential of existing policy options and to advance the transition towards global net zero greenhouse gas emissions. Key policy insights: Mitigation-related policy options can be presented as a matrix by sector to shed light on what constitutes a comprehensive climate policy package; looking across sectoral climate policies helps to unpack and clarify the status of adoption. Policy adoption gaps exist in all sectors. Increasing the sectoral coverage of climate policies will help to ensure that all relevant sectoral emissions and mitigation areas are considered in national mitigation efforts. Even if an increase in policy coverage alone does not ensure emission reductions, the absence of policy coverage indicates that emissions can still be further reduced and that a portion of global emissions remain uncovered by policies. Despite the observed increase in the number and coverage of climate policies, slow progress towards reducing global emissions and meeting the collective Paris climate goals calls for more comprehensive climate change mitigation policies. Filling policy adoption gaps presents a concrete strategy to improve sectoral, national and global climate policy

Greenhouse gas emission scenarios in nine key non-G20 countries: An assessment of progress toward 2030 climate targets

This study compares greenhouse gas (GHG) emissions projections in 2030 under current policies and those under 2030 mitigation targets for nine key non-G20 countries, that collectively account for about 5 % of global total emissions today. These include the four largest non-G20 fossil CO2 emitting Parties to the UN climate convention pre- Paris Agreement (Iran, Kazakhstan, Thailand and Ukraine) and one of the largest land-use GHG emitters in the world (Democratic Republic of the Congo). Other countries assessed include major economies in their respective regions (Chile, Colombia, Morocco and the Philippines). In addition to economy-wide GHG emissions projections, we also assessed the projected GHG emissions peak year and the progression of per capita GHG emissions up to 2030. Our GHG emissions projections are also compared with previous studies. On economy-wide GHG emissions, Colombia, Iran, Morocco, and Ukraine were projected to likely meet or significantly overachieve their unconditional 2030 targets with existing policies, while DRC and Thailand would come very close to their targets. Kazakhstan and the Philippines would need to strengthen their action to meet their targets, while Chile recently raised its 2030 target ambition. Only Colombia and Ukraine are projected to have peaked their emissions by 2030. Per capita GHG emissions excluding land-use under current policies were projected to increase in all countries from 2010 levels by 8 % to over 40 % depending on the country. While the impact of the COVID-19 crisis on 2030 emissions is highly uncertain, our assessment on the target achievement would not change for most countries when the emission reductions estimated for 2020 in the literature were assumed to remain in 2030. The findings of this study highlight the importance of enhanced and frequent progress-tracking of climate action of major emitters outside G20, as is currently done for G20 members, to ensure that the global collective progress will become aligned with the pathways toward Paris climate goals

Greenhouse gas emission scenarios in nine key non-G20 countries: An assessment of progress toward 2030 climate targets

This study compares greenhouse gas (GHG) emissions projections in 2030 under current policies and those under 2030 mitigation targets for nine key non-G20 countries, that collectively account for about 5 % of global total emissions today. These include the four largest non-G20 fossil CO2 emitting Parties to the UN climate convention pre- Paris Agreement (Iran, Kazakhstan, Thailand and Ukraine) and one of the largest land-use GHG emitters in the world (Democratic Republic of the Congo). Other countries assessed include major economies in their respective regions (Chile, Colombia, Morocco and the Philippines). In addition to economy-wide GHG emissions projections, we also assessed the projected GHG emissions peak year and the progression of per capita GHG emissions up to 2030. Our GHG emissions projections are also compared with previous studies. On economy-wide GHG emissions, Colombia, Iran, Morocco, and Ukraine were projected to likely meet or significantly overachieve their unconditional 2030 targets with existing policies, while DRC and Thailand would come very close to their targets. Kazakhstan and the Philippines would need to strengthen their action to meet their targets, while Chile recently raised its 2030 target ambition. Only Colombia and Ukraine are projected to have peaked their emissions by 2030. Per capita GHG emissions excluding land-use under current policies were projected to increase in all countries from 2010 levels by 8 % to over 40 % depending on the country. While the impact of the COVID-19 crisis on 2030 emissions is highly uncertain, our assessment on the target achievement would not change for most countries when the emission reductions estimated for 2020 in the literature were assumed to remain in 2030. The findings of this study highlight the importance of enhanced and frequent progress-tracking of climate action of major emitters outside G20, as is currently done for G20 members, to ensure that the global collective progress will become aligned with the pathways toward Paris climate goals

Wses Guidelines For Management Of Clostridium Difficile Infection In Surgical Patients

In the last two decades there have been dramatic changes in the epidemiology of Clostridium difficile infection (CDI), with increases in incidence and severity of disease in many countries worldwide. The incidence of CDI has also increased in surgical patients. Optimization of management of C difficile, has therefore become increasingly urgent. An international multidisciplinary panel of experts prepared evidenced-based World Society of Emergency Surgery (WSES) guidelines for management of CDI in surgical patients.1

Salivary Glucose Oxidase from Caterpillars Mediates the Induction of Rapid and Delayed-Induced Defenses in the Tomato Plant

Caterpillars produce oral secretions that may serve as cues to elicit plant defenses, but in other cases these secretions have been shown to suppress plant defenses. Ongoing work in our laboratory has focused on the salivary secretions of the tomato fruitworm, Helicoverpa zea. In previous studies we have shown that saliva and its principal component glucose oxidase acts as an effector by suppressing defenses in tobacco. In this current study, we report that saliva elicits a burst of jasmonic acid (JA) and the induction of late responding defense genes such as proteinase inhibitor 2 (Pin2). Transcripts encoding early response genes associated with the JA pathway were not affected by saliva. We also observed a delayed response to saliva with increased densities of Type VI glandular trichomes in newly emerged leaves. Proteomic analysis of saliva revealed glucose oxidase (GOX) was the most abundant protein identified and we confirmed that it plays a primary role in the induction of defenses in tomato. These results suggest that the recognition of GOX in tomato may represent a case for effector-triggered immunity. Examination of saliva from other caterpillar species indicates that saliva from the noctuids Spodoptera exigua and Heliothis virescens also induced Pin2 transcripts