Study of Transport of Nanoparticles with K-L Model Through a Stenosed Microvessels

This paper studies a constitutive equation for blood with the transport of nanoparticles in a stenosed microvessel. The flow of blood through a bell-shaped stenosed micro blood vessel has been investigated with an importance of permeable walls that treats blood as non-Newtonian fluid by using K-L model. This model is more appropriate than other non-Newtonian models because K-L model involve three parameters such as plasma viscosity, yield stress and one other chemical variable while casson model involves only one parameter i.e. yield stress. In the present paper, the effective longitudinal diffusion of nanoparticles has been studied in stenosed blood vessel considering the contribution of molecular and convective diffusion based on Taylor\u27s theory. Also we analyze the flow characteristics of blood such as velocity, flow rate and effective diffusion during a nanoparticle assisted drug delivery process through a stenosed permeable microvessel. An explicit expression has been derived for velocity, flow rate and effective diffusion of nanoparticles depending non-linearly on rheological parameter, stenosis height and plasma viscosity. It has been shown that for a given values of rheological parameter, stenosis height and plasma viscosity, fluid velocity is maximum at the central axis and flow rate is minimum at the axis of symmetry. Also it has concluded that the effective diffusion of nanoparticles is maximum at the vessel walls and minimum at the axis of symmetry

Systemic lupus erythematosus in pregnancy with rare anomaly of rhizomelic chondrodysplasia punctata in baby

Rhizomelic means shortening of the bones closest to the body’s trunk. Chondrodysplasia refers to malformation (the dysplasia part of the word) of the cartilage (the chondro part of the word). Punctata refers to an unusual stippling on the end of the bones that join the shoulders and elbows (the humerus) and the top of the leg and the hip (femur). On X-ray an infant’s bones look spotty at the ends. Here, we report a case of rhizomelic chondrodysplasia punctate (RCDP) in newborn of a known systemic lupus erythematosus (SLE) patient. Consent for publication of this rare case for academic benefit has been taken from the patient

Cost Analysis of a Compound System with the Concept of Waiting

In this research paper the authors, Suppose a compound system having two sub-systems namely ‘P’ and ‘Q’ connected in chain. Sub-system ‘P’ consists of n unlike units in chain, while sub-system ‘Q’ consists of m like units chain. The compound system is subjected to minor failure, major failure critical human failure and common cause failure. Keywords – Asymptotic behavior, Availability of function, Abel lemma, Cost function and Supplementary variable technique.

Dispersion Characteristics of non-Newtonian fluid during transportation of nanoparticles in permeable capillary

The present analysis deals with the dispersion characteristics of blood described as Herschel- Bulkley fluid in capillary with permeable walls for fluid and impermeable for the nanoparticles. The contribution of molecular and convective diffusion is recalled from the Taylor and Aris coefficient of diffusion. The effective longitudinal diffusion depends on three parameters namely rheological parameter, pressure parameter, and the permeability parameter. We investigate the influence of the longitudinal transport of nanoparticles with permeable blood vessels on the effective dispersion. It shows that the effective diffusion of nanoparticles reduces with increase in radius of the plug region (i.e., the volume of red blood cells) and the permeability of the blood vessels

Study of Transport of Nanoparticles with Power Law fluid Model for Blood Rheology in Capillaries

The present paper deals with a mathematical model for blood flow through an axially symmetric blood capillary with peripheral layer and slip at the wall. The longitudinal transport of nanoparticles in blood vessels has been analyzed with blood as a power law fluid in a central core region of suspension of all the erythrocytes and a Newtonian fluid in a peripheral layer of plasma. In present analysis, the capillary walls are impermeable and not absorbent for the nanoparticles. The expressions for velocity profile, flow rate, mean velocity and concentration of the solute have been obtained and results have been discussed through graphs

Uncharted territory: endometeriosis explored in the left canal of Nuck

In this captivating exploration, we unravel a perplexing case of endometriosis taking root within the enigmatic left canal of Nuck. A 33-year-old woman with a tenacious groin mass, manifesting occasional discomfort during menstruation, led us down a diagnostic rabbit hole. Through ultrasound and MRI revelations, a mass emerged, stretching through the left inguinal canal into the pubic domain. The subsequent cytological analysis solidified the diagnosis. While endometriosis, characterized by extrinsic endometrial tissue, typically confines its grip to the pelvic arena, this singular case defies convention. The canal of Nuck, a developmental vestige, reveals itself as a potential portal for endometrial cells under enigmatic conditions. Amid diagnostic intricacies, ultrasound and MRI step forth as guiding imaging tools. In a medical landscape rife with the known, this expedition into the uncharted expands our understanding and beckons us to probe further into the remarkable intricacies of Nuck's canal endometriosis

Acceptance, safety and complications of postpartum intra uterine contraceptive device: a prospective study in tertiary care hospital

Background: Intrauterine contraceptive device is a long acting, effective and reversible method of contraception. It can be inserted post placental during vaginal or LSCS delivery and within 48 hours of delivery.  This study evaluates the acceptance, safety, side effects and complications associated with immediate post-partum intrauterine contraceptive device (PPIUCD) insertion.Methods: The study was conducted at Hindu Rao Hospital and NDMC Medical College, Delhi for a period of 18 months. Patients admitted and delivered at Hindu Rao Hospital were counseled for PPIUCD, CuT 380 A / CuT 375 insertions and it was inserted within 10 minutes of delivery of placenta during vaginal delivery or LSCS or within 48 hours of delivery. Patients were followed at 6 weeks and then between 6 to 12 months of delivery for continuation, side effects or any complications.Results: After counseling 1253 (9.8%) patients agreed for PPIUCD insertion out of which 650 patients came for follow up. 46% women came for routine follow up while 54.06% came with one or the other complications. Missed thread was most common complications, followed by bleeding P/V and pain abdomen. Expulsion in 5.5% and CuT failure was seen in 0.92% women only. Removal of IUCD was done in 94 patients for one or other reasons. There was retention of PPIUCD in 84.5% while removal was done in 14.5% during period of 6 months to one year follow up. Missed thread was main cause of anxiety among acceptors.Conclusions: Immediate PPIUCD is safe and effective method of contraception with a high retention rate. Though acceptance in initial months was less but it gradually increased over time with increasing awareness, counseling of patients and training of health personnel

Operational Readiness of a Complex System under Different Weather Conditions

The authors have considered a complex system composed of single repairable unit and operating in ‘n’ multiple environmental conditions. The system may either go to complete breakdown shape due to common cause failure or it may go to any one of the abnormal weather operation states. The system is repairable from the degraded state. The failed system is assumed to be repaired back to its normal weather and abnormal weather operation states. Keywords: Availability/Reliability Analysis, Repairable Parallel System, Laplace transform, Ergodic system , Abel Lemma, supplementary variable technique and Steady- state behavior

Effect of Different Curing Conditions on Geopolymer Concrete by Partially Replacing sand with Foundry sand

In the present paper, fly ash (no other solid material was used) with highly alkaline solutions is described. These solutions, made with NaOH, Na2Sio3.This paper, report on the study of the processing of geopolymer using fly ash and alkaline activator with geopolymerization process. The factors that influence flexural strength such as different curing condition. The fly ash, fine aggregate with replacement of foundry sand, coarse aggregats and alkaline solution were is used to make geopolymer concrete. The foundry sand is replaced by normal sand in different amount. The main purpose of replacement of foundry sand in to utilize waste by product and save environment also to see the effect on proprety of geopolymer concrete. The flexural strength is carriedout by UT machine at 7 and 28 days

Measures of Different Reliability Parameters for a Complex Redundant System Under Head-of-Line Repair

The authors have considered a complex system consisting of two subsystems designated as ‘A’ and ‘B’ connected in series. Subsystem ‘A’ consists of N non-identical units in series, while the subsystem ‘B’ consists of three identical components in parallel redundancy. Keywords: Availability/Reliability Analysis, Repairable Parallel System, Laplace transform, cost profit function, Head-of-line Repair