MALNUTRITION-CHALLENGE IN 21ST CENTURY AND PROBABLE CONTRIBUTION OF AYURVEDA THROUGH MORINGA LEAVES

Nutritive diet has grabbed the center stage in current times among common men as well as researchers &food has turned into a whole damn industry. Despite of everything, Malnutrition is the largest single contributor to diseases in the world & leads to 45% of all deaths in children under 5 in developing countries. Due to interrelated mother- child nutrition, if a breastfeeding mother gets required nutrition, her kid becomes healthy. The causes of improper nutrition are variable but lack of nutritious food combinations in all classes are most important throughout the world. Ayurveda is science of individualistic need based dietetics & nutrition and describes foods accordingly. There is recommendation of a super food named Shigru (Moringa) for Sutika (lactating mothers) in Bheshajyaratnawali,taking this as reference we have conceptualized a food combination of Moringa +wheat flour+ jaggery which is super nutritious and serves as a cheap, affordable, easy to collect and easy to make, palatable preparation. When 11% of the world’s population is under nourished, need for such right food combination increases manifolds. Owing to per 100g nutritive value of these contents and their cost effectiveness, this combination has a potential to be a perfect staple dietary option for nutrition deficit individuals. It needs to be further established at large scale through RCTs so that large population can be benefitted

Nations within a nation: variations in epidemiological transition across the states of India, 1990–2016 in the Global Burden of Disease Study

18% of the world's population lives in India, and many states of India have populations similar to those of large countries. Action to effectively improve population health in India requires availability of reliable and comprehensive state-level estimates of disease burden and risk factors over time. Such comprehensive estimates have not been available so far for all major diseases and risk factors. Thus, we aimed to estimate the disease burden and risk factors in every state of India as part of the Global Burden of Disease (GBD) Study 2016

Neck massage induced dural sinus thrombosis

Thrombosis of the intracranial dural sinuses and internal jugular veins may occur as a complication of head and neck infections, surgery, central venous access, local malignancy, polycythemia, hyperhomocysteinemia, neck massage and intravenous drug abuse. A high degree of clinical suspicion followed by adequate imaging is prerequisite to early diagnosis and management. We report a young man who had dural sinus thrombosis with jugular venous thrombosis following neck massage

Detection of Promoter DNA Methylation of <i>APC</i>, <i>DAPK</i>, and <i>GSTP1</i> Genes in tissue Biopsy and Matched Serum of Advanced-Stage Lung Cancer Patients

<p>Promoter DNA hypermethylation of <i>APC, DAPK</i>, and <i>GSTP1</i> genes was evaluated in biopsy and matched serum of 160 lung cancer patients and 70 controls. In biopsy, 83.1, 83.1, and 78.1% of lung cancer patients and 72.9, 70, and 70% of controls, while in serum, 52.5, 30.6, and 65.6% of lung cancer patients and 14.3, 18.6, and 30% of controls were positive for <i>APC, DAPK</i>, and <i>GSTP1</i> hypermethylation respectively. We couldn't find any significant role of DNA hypermethylation in lung cancer. However, long follow-up of methylation positive controls will be required to confirm its role for the prediction of lung cancer.</p

NOTTO COVID-19 vaccine guidelines for transplant recipients

In December 2019, novel coronavirus (SARS-CoV-2) infection started in Wuhan and resulted in a pandemic within a few weeks' time. Organ transplant recipients being at a risk for more severe COVID-19 if they get SARS CoV-2 viral infection, COVID-19 vaccine has a significant role in these patients. The vaccine is a safer way to help build protection and would either prevent COVID-19 infection or at least diminish the severity of the disease. It would also reduce the risk of the continuing transmission and enhance herd immunity. Immuno-compromised patients should not receive live vaccines as they can cause vaccine-related disease and hence the guidelines suggest that all transplant recipients should receive age-appropriate 'inactivated vaccine' as recommended for general population. Though trials have not been undertaken on transplant recipients, efficacy and safety of COVID-19 vaccine have been scientifically documented for few vaccines among the general population