60 research outputs found
Geometric local epsilon-factors in higher dimensions
We prove a product formula for the determinant of the cohomology of an Ă©tale sheaf with -adic coefficients over an arbitrary proper scheme over a perfect field of positive characteristic p distinct from. The local contributions are constructed by iterating vanishing cycle functors as well as certain exact additive functors that can be considered as linearised versions of Artin conductors and local -factors. We provide several applications of our higher dimensional product formula, such as twist formulas for global -factors
On the slopes of the lattice of sections of hermitian line bundles
In this paper we apply Arakelov theory to study the distribution of the Petersson norms of classical cusp forms as well as the distribution of the sup norms of rational functions on adelic subsets of curves. The method in both cases is to study the limiting distribution of the successive minima of norms of global sections of powers of a metrized ample line bundle as one takes increasing powers of the bundle. We develop a general method for computing the measure associated to this distribution. We also study measures associated to the zeros of sections which have small norm
Critical Role of Constitutive Type I Interferon Response in Bronchial Epithelial Cell to Influenza Infection
Innate antiviral responses in bronchial epithelial cells (BECs) provide the first line of defense against respiratory viral infection and the effectiveness of this response is critically dependent on the type I interferons (IFNs). However the importance of the antiviral responses in BECs during influenza infection is not well understood. We profiled the innate immune response to infection with H3N2 and H5N1 virus using Calu-3 cells and primary BECs to model proximal airway cells. The susceptibility of BECs to influenza infection was not solely dependent on the sialic acid-bearing glycoprotein, and antiviral responses that occurred after viral endocytosis was more important in limiting viral replication. The early antiviral response and apoptosis correlated with the ability to limit viral replication. Both viruses reduced RIG-I associated antiviral responses and subsequent induction of IFN-β. However it was found that there was constitutive release of IFN-β by BECs and this was critical in inducing late antiviral signaling via type I IFN receptors, and was crucial in limiting viral infection. This study characterizes anti-influenza virus responses in airway epithelial cells and shows that constitutive IFN-β release plays a more important role in initiating protective late IFN-stimulated responses during human influenza infection in bronchial epithelial cells
Large-scale unit commitment under uncertainty: an updated literature survey
The Unit Commitment problem in energy management aims at finding the optimal production schedule of a set of generation units, while meeting various system-wide constraints. It has always been a large-scale, non-convex, difficult problem, especially in view of the fact that, due to operational requirements, it has to be solved in an unreasonably small time for its size. Recently, growing renewable energy shares have strongly increased the level of uncertainty in the system, making the (ideal) Unit Commitment model a large-scale, non-convex and uncertain (stochastic, robust, chance-constrained) program. We provide a survey of the literature on methods for the Uncertain Unit Commitment problem, in all its variants. We start with a review of the main contributions on solution methods for the deterministic versions of the problem, focussing on those based on mathematical programming techniques that are more relevant for the uncertain versions of the problem. We then present and categorize the approaches to the latter, while providing entry points to the relevant literature on optimization under uncertainty. This is an updated version of the paper "Large-scale Unit Commitment under uncertainty: a literature survey" that appeared in 4OR 13(2), 115--171 (2015); this version has over 170 more citations, most of which appeared in the last three years, proving how fast the literature on uncertain Unit Commitment evolves, and therefore the interest in this subject
Multiple-reaction monitoring liquid chromatography mass spectrometry for monosaccharide compositional analysis of glycoproteins
IR Li2Ga2GeS6 nanocrystallized GeS2-Ga2S3-Li2S electroconductive chalcogenide glass with good nonlinearity
The Forest Rights Act: A major driver of Forest Landscape Changes in Southern India?
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Multilevel multi-leader multiple-follower games with nonseparable objectives and shared constraints
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