Regional development strategies of a new regional government: The Junta de Andalucia, 1984-90.

The creation of the 'State of the Autonomies', embodied in the 1978 Spanish Constitution, brought to Andalucia the devolution of wide political powers and administrative functions, and with this, the possibility for the newly created Junta de Andalucia of implementing a development policy wholly different from that of the central government and from those of other autonomous communities. Different from other historical regions, such as Catalonia or the Basque Country, run by conservative and nationalist parties, the Socialist party in Andalucia from the first moment linked political autonomy and regional economic development. Underdeveloped, marginal from main national and international economic circuits, and run by a socialist regional government that wanted to repair the comparative wrongs suffered historically by the region, Andalucia enjoyed at the beginning of the 1980's optimal conditions for implementing a self-reliant strategy of regional development. In order to identify, interpret, and analyse the evolution of the strategy of development of the Junta de Andalucia during the 1984-90 period, the thesis reviews policy and resource allocation in three policy-sectors: road, railway, and industrial promotion. In each case, a genuine self-reliant philosophy appears at the beginning of the period, which is, however, abandoned in the middle 1980's and substituted by a development strategy based on functional integration into larger-scale systems. Using policy documents and interviews with decision-makers and researchers, the thesis attempts to explain the observed shift and to interpret the logic of the regional development strategies pursued by the Junta de Andalucia during its first decade. Political legitimation, during the period of economic recession, and economic accumulation, when pressures to support the internationalization process of capital appeared, guided regional planning policy of the Junta during its first decade. The thesis ends by relating the evolution followed by the regional planning policy of the Junta to wider debate about decentralization and regional theory and policy

Habilidades directivas y la motivación laboral en las instituciones educativas de la red 8 del nivel inicial, Ugel 05, San Juan de Lurigancho – 2018

La indagación titulada Habilidades directivas y la motivación laboral en las Instituciones Educativas de la Red 8 del nivel inicial, UGEL 05, San Juan de Lurigancho – 2018, tuvo como objetivo determinar la relación que existe entre las habilidades directivas y la motivación laboral en las instituciones educativas de la RED 08 del nivel inicial, UGEL 05, San Juan de Lurigancho – 2018. La metodología en encuadra en el paradigma cuantitativo, método hipotético deductivo, de nivel descriptivo – correlacional. Diseño no experimental, con corte transversal sustentado por Hernández, Fernández y Baptista (2010). La población quedó conformada por 76 docentes. Se trabajó con una muestra censal. La técnica utilizada fue la encuesta y como instrumento el cuestionario que se aplico para recolectar datos de ambas variables. Para la confiabilidad de los instrumentos se usó Alpha de Cronbach para ambos instrumentos. Los datos obtenidos han sido procesadas en el SPSS versión 25.0, y finalmente fueron presentadas mediante tablas y gráficos. La indagación concluye existe relación significativa entre las variables habilidades directivas y motivación laboral. La muestra estadística indicó que es significativo al nivel de 0,01, con una p=0,00 (p < 0,05); por lo que rechaza la hipótesis nula y se acepta la hipótesis alterna. Se obtuvo un coeficiente de correlación de Rho de Spearman = 0,749** interpretándose como una alta relación positiva entre las variables, Por lo tanto, el investigador sostiene que: la correlación entre las variables habilidades directivas y motivación laboral es positiva y alta

The X-ray nature of the LINER nuclear sources

The analysis of the X-ray data for a sample of 51 LINER nuclei with available X-ray Chandra imaging is reported. Our aim was to investigate the physical mechanisms which power LINER nuclear activity. The use of multiwavelenght information at radio, UV, optical HST and X-ray lead us to conclude that at least 60% of the LINERs are hosting a low luminosity AGN in their nuclei. This percentage may be even higher if the Compton-thickness of some nuclei (mostly with SB-like hard X-ray morphology) is confirmed.Comment: Conference proceedings to appear in "The Central Engine of Active Galactic Nuclei", ed. L.C. Ho and J.-M. Wang (San Francisco: ASP

Gelation properties of calcium-inulin gels

Inulin is a prebiotic ingredient that is being increasingly used in food formulations as fat replacer. The present manuscript focuses on the formation of gels formed from inulin aqueous dispersions, observing the effect of inulin content, ranging from 25 to 50 wt%, and of the presence of calcium salts (chloride, lactate) at different concentrations up to 5 wt% Gels are observed to be stronger and formed in a shorter time as the polysaccharide content is higher. Both backscattering and rheological techniques can be used to follow the gelation, being able to detect a significant initial setting stage at 25 wt% inulin content. When calcium salts are added, weakening of gels takes place, resulting in lower values of the storage and loss moduli, G′ and G″, respectively, as well as in a reduction of the linear viscoelastic range. Moreover, gelation seems to be retarded on a large scale of time due to the presence of salt. Prebiotic gels containing calcium are of special interest for the development of functional foods, always considering the effect they exert on the rheology when formulating these products.Fil: Bengoechea, Carlos. Universidad de Sevilla; EspañaFil: López-Castejón, María Luisa. Universidad de Sevilla; EspañaFil: Marquez, Sandra Margarita. Universidad de Sevilla; EspañaFil: Salinas, Maria Victoria. Provincia de Buenos Aires. Gobernación. Comisión de Investigaciones Científicas. Centro de Investigación y Desarrollo en Criotecnología de Alimentos. Consejo Nacional de Investigaciones Científicas y Técnicas. Centro Científico Tecnológico Conicet - La Plata. Centro de Investigación y Desarrollo en Criotecnología de Alimentos. Universidad Nacional de la Plata. Facultad de Ciencias Exactas. Centro de Investigación y Desarrollo en Criotecnología de Alimentos; ArgentinaFil: Puppo, Maria Cecilia. Provincia de Buenos Aires. Gobernación. Comisión de Investigaciones Científicas. Centro de Investigación y Desarrollo en Criotecnología de Alimentos. Consejo Nacional de Investigaciones Científicas y Técnicas. Centro Científico Tecnológico Conicet - La Plata. Centro de Investigación y Desarrollo en Criotecnología de Alimentos. Universidad Nacional de la Plata. Facultad de Ciencias Exactas. Centro de Investigación y Desarrollo en Criotecnología de Alimentos; ArgentinaFil: Guerrero, Antonio. Universidad de Sevilla; Españ

SEOM-GEM clinical guidelines for cutaneous melanoma (2023)

Melanoma; Staging; Targeted therapyMelanoma; Estadificación; Terapia dirigidaMelanoma; Estadificació; Teràpia dirigidaCutaneous melanoma incidence is rising. Early diagnosis and treatment administration are key for increasing the chances of survival. For patients with locoregional advanced melanoma that can be treated with complete resection, adjuvant—and more recently neoadjuvant—with targeted therapy—BRAF and MEK inhibitors—and immunotherapy—anti-PD-1-based therapies—offer opportunities to reduce the risk of relapse and distant metastases. For patients with advanced disease not amenable to radical treatment, these treatments offer an unprecedented increase in overall survival. A group of medical oncologists from the Spanish Society of Medical Oncology (SEOM) and Spanish Multidisciplinary Melanoma Group (GEM) has designed these guidelines, based on a thorough review of the best evidence available. The following guidelines try to cover all the aspects from the diagnosis—clinical, pathological, and molecular—staging, risk stratification, adjuvant therapy, advanced disease therapy, and survivor follow-up, including special situations, such as brain metastases, refractory disease, and treatment sequencing. We aim help clinicians in the decision-making process

TRACKING LEAD (Pb) IN THE ENVIRONMENT OF JAKARA, KANO STATE, NIGERIA

Lead is considered a toxic substance that is already available in environment and has health impacts. The objective of the present study is to track the availability of lead in the environment of Jakara, Kano State, Nigeria. Lead was tracked in water, soil, and vegetables including lettuce, spinach, and onion. Study methodology involved taking random samples from water, soil, and vegetables at Jakara. Samples were prepared and assayed by atomic absorption spectrometry. Study findings showed that the mean concentration of lead in water was 0.115±0.023 mg/l, while it was in soil 2.46 ±0.95 μg/g. The mean concentration of lead in both lettuce and spinach was the same (22.95+ 3.28 mg/kg), and in onion was 19.67 ±3.28 mg/kg . Conclusions: the present study showed that there is a lead contamination of Jakara region by heavy metal (lead). This contamination is evident in water, soil, and vegetables

Intensive care adult patients with severe respiratory failure caused by Influenza A (H1N1)v in Spain

Introduction: Patients with influenza A (H1N1)v infection have developed rapidly progressive lower respiratory tract disease resulting in respiratory failure. We describe the clinical and epidemiologic characteristics of the first 32 persons reported to be admitted to the intensive care unit (ICU) due to influenza A (H1N1)v infection in Spain. Methods: We used medical chart reviews to collect data on ICU adult patients reported in a standardized form. Influenza A (H1N1)v infection was confirmed in specimens using real-time reverse transcriptase-polymerase-chain-reaction (RT PCR) assay. Results: Illness onset of the 32 patients occurred between 23 June and 31 July, 2009. The median age was 36 years (IQR = 31 - 52). Ten (31.2%) were obese, 2 (6.3%) pregnant and 16 (50%) had pre-existing medical complications. Twenty-nine (90.6%) had primary viral pneumonitis, 2 (6.3%) exacerbation of structural respiratory disease and 1 (3.1%) secondary bacterial pneumonia. Twenty-four patients (75.0%) developed multiorgan dysfunction, 7 (21.9%) received renal replacement techniques and 24 (75.0%) required mechanical ventilation. Six patients died within 28 days, with two additional late deaths. Oseltamivir administration delay ranged from 2 to 8 days after illness onset, 31.2% received high-dose (300 mg/day), and treatment duration ranged from 5 to 10 days (mean 8.0 +/- 3.3). Conclusions: Over a 5-week period, influenza A (H1N1)v infection led to ICU admission in 32 adult patients, with frequently observed severe hypoxemia and a relatively high case-fatality rate. Clinicians should be aware of pulmonary complications of influenza A (H1N1)v infection, particularly in pregnant and young obese but previously healthy persons

A histologic scoring system for prognosis of patients with Alcoholic hepatitis

BACKGROUND & AIMS: There is no histologic classification system to determine prognoses of patients with alcoholic hepatitis (AH). We identified histologic features associated with disease severity and created a histologic scoring system to predict short-term (90-day) mortality. METHODS: We analyzed data from 121 patients admitted to the Liver Unit (Hospital Clinic, Barcelona, Spain) from January 2000 to January 2008 with features of AH and developed a histologic scoring system to determine the risk of death using logistic regression. The system was tested and updated in a test set of 96 patients from 5 academic centers in the United States and Europe, and a semiquantitative scoring system called the Alcoholic Hepatitis Histologic Score (AHHS) was developed. The system was validated in an independent set of 109 patients. Interobserver agreement was evaluated by weighted κ statistical analysis. RESULTS: The degree of fibrosis, degree of neutrophil infiltration, type of bilirubinostasis, and presence of megamitochondria were independently associated with 90-day mortality. We used these 4 parameters to develop the AHHS to identify patients with a low (0-3 points), moderate (4-5 points), or high (6-9 points) risk of death within 90 days (3%, 19%, and 51%, respectively; P < .0001). The AHHS estimated 90-day mortality in the training and test sets with an area under the receiver operating characteristic value of 0.77 (95% confidence interval, 0.71-0.83). Interrater agreement values were 0.65 for fibrosis, 0.86 for bilirubinostasis, 0.60 for neutrophil infiltration, and 0.46 for megamitochondria. Interestingly, the type of bilirubinostasis predicted the development of bacterial infections. CONCLUSIONS: We identified histologic features associated with the severity of AH and developed a patient classification system that might be used in clinical decision making