Connectivity-Enforcing Hough Transform for the Robust Extraction of Line Segments

Global voting schemes based on the Hough transform (HT) have been widely used to robustly detect lines in images. However, since the votes do not take line connectivity into account, these methods do not deal well with cluttered images. In opposition, the so-called local methods enforce connectivity but lack robustness to deal with challenging situations that occur in many realistic scenarios, e.g., when line segments cross or when long segments are corrupted. In this paper, we address the critical limitations of the HT as a line segment extractor by incorporating connectivity in the voting process. This is done by only accounting for the contributions of edge points lying in increasingly larger neighborhoods and whose position and directional content agree with potential line segments. As a result, our method, which we call STRAIGHT (Segment exTRAction by connectivity-enforcInG HT), extracts the longest connected segments in each location of the image, thus also integrating into the HT voting process the usually separate step of individual segment extraction. The usage of the Hough space mapping and a corresponding hierarchical implementation make our approach computationally feasible. We present experiments that illustrate, with synthetic and real images, how STRAIGHT succeeds in extracting complete segments in several situations where current methods fail.Comment: Submitted for publicatio

Tuned liquid dampers simulation for earthquake response control of buildings

This paper is focused on the study of an earthquake protection system, the Tuned Liquid Damper (TLD), which can, if adequately designed, reduce earthquake demands on buildings. This positive effect is accomplished taking into account the oscillation of the free surface of a fluid inside a tank (sloshing). The behaviour of an isolated Tuned Liquid Damper, subjected to a sinusoidal excitation at its base, with different displacement amplitudes, was studied by finite element analysis. The efficiency of the TLD in improving the seismic response of an existing building, representative of modern architecture buildings in southern European countries was also evaluated based on linear dynamic analyses

Automatic truecasing of video subtitles using BERT: a multilingual adaptable approach

This paper describes an approach for automatic capitalization of text without case information, such as spoken transcripts of video subtitles, produced by automatic speech recognition systems. Our approach is based on pre-trained contextualized word embeddings, requires only a small portion of data for training when compared with traditional approaches, and is able to achieve state-of-the-art results. The paper reports experiments both on general written data from the European Parliament, and on video subtitles, revealing that the proposed approach is suitable for performing capitalization, not only in each one of the domains, but also in a cross-domain scenario. We have also created a versatile multilingual model, and the conducted experiments show that good results can be achieved both for monolingual and multilingual data. Finally, we applied domain adaptation by finetuning models, initially trained on general written data, on video subtitles, revealing gains over other approaches not only in performance but also in terms of computational cost.info:eu-repo/semantics/publishedVersio

Late Onset Temporal Lobe Epilepsy With Mri Evidence Of Mesial Temporal Sclerosis Following Acute Neurocysticercosis: Case Report.

The objective of this case report is to describe magnetic resonance imaging (MRI) evidence of mesial temporal sclerosis (MTS) in a patient with new onset temporal lobe epilepsy (TLE) and acute neurocysticercosis with multiple cysts. A 56 years old man with new onset headache, Simple Partial Seizures and Complex Partial Seizures underwent CT scan and lumbar puncture as diagnose proceeding. Multiple cysts and meningitis were identified, with a positive immunology for cysticercosis. Seizures were recorded over the left temporal region in a routine EEG. Treatment with albendazole was performed for 21 days, with clinical improvement and seizure remission after 4 months. An MRI scan 11 months after treatment, showed complete resolution of those cystic lesions and a left hippocampal atrophy (HA) with hyperintense T2 signal. The presence of HA and hyperintense T2 signal in this patient has not, to date, been associated with a poor seizure control. This patient presented with MRI evidence of left MTS after new onset partial seizures of left temporal lobe origin. Although we did not have a previous MRI scan, it is likely that this hippocampal abnormality was due to the acute inflammatory response to cysticercosis associated to repeated partial seizures. This suggests that acute neurocysticercosis associated with repeated seizures may cause MTS and late onset TLE.59255-

The spectraplakin Dystonin antagonizes YAP activity and suppresses tumourigenesis

Aberrant expression of the Spectraplakin Dystonin (DST) has been observed in various cancers, including those of the breast. However, little is known about its role in carcinogenesis. In this report, we demonstrate that Dystonin is a candidate tumour suppressor in breast cancer and provide an underlying molecular mechanism. We show that in MCF10A cells, Dystonin is necessary to restrain cell growth, anchorage-independent growth, self-renewal properties and resistance to doxorubicin. Strikingly, while Dystonin maintains focal adhesion integrity, promotes cell spreading and cell-substratum adhesion, it prevents Zyxin accumulation, stabilizes LATS and restricts YAP activation. Moreover, treating DST-depleted MCF10A cells with the YAP inhibitor Verteporfin prevents their growth. In vivo, the Drosophila Dystonin Short stop also restricts tissue growth by limiting Yorkie activity. As the two Dystonin isoforms BPAG1eA and BPAG1e are necessary to inhibit the acquisition of transformed features and are both downregulated in breast tumour samples and in MCF10A cells with conditional induction of the Src proto-oncogene, they could function as the predominant Dystonin tumour suppressor variants in breast epithelial cells. Thus, their loss could deem as promising prognostic biomarkers for breast cancer.The authors acknowledge the support of the Bloomington Drosophila Stock Centre, the National Institute of Genetics (NIG-Fly) the services of the Animal, Imaging and Cytometry and Genomics facilities at Instituto Gulbenkian de Ciência, and of the i3S Scientific Platforms, including the Cell Culture and Genotyping (CCGen) and the Genomics (GenCore) platforms, as well as the Bioimaging and the Advanced Light Microscopy platforms. We are also grateful to M. J. Amorim and N. Tapon for reagents and to A. Monteiro for fly food preparation. We specially thank K. Struhl for providing the TAM-inducible ER-Src and PBabe cell lines and Rafeeq Mir, Eurico Morais-de-Sá, Archana Pawar and Carla Oliveira for comments on the manuscript. This work was supported by funds from Fundação para a Ciência e Tecnologia (FCT), co-financed by Fundo Europeu de Desenvolvimento Regional (FEDER) through Programa Operacional Competitividade e Internacionalização (POCI) (POCI-01-0145-FEDER-016390) and the Laço Grant in breast cancer 2015 to F.J. The i3S Bioimaging and Advanced Light Microscopy scientific platforms are both member of the national infrastructure PPBI-Portuguese Platform of BioImaging, supported by POCI-01-0145-FEDER-022122. P.J. was the recipient of fellowships from FCT (PD/ BD/52439/2013). F.J. was the recipient of IF/01031/2012

Simple ears inspire frequency agility in an engineered acoustic sensor system

Standard microphones and ultrasonic devices are generally designed with a static and flat frequency response in order to address multiple acoustic applications. However, they may not be flexible or adaptable enough to deal with some requirements. For instance, when operated in noisy environments such devices may be vulnerable to wideband background noise which will require further signal processing techniques to remove it, generally relying on digital processor units. In this work, we consider if microphones and ultrasonic devices could be designed to be sensitive only at selected frequencies of interest, whilst also providing flexibility in order to adapt to different signals of interest and to deal with environmental demands. This research exploits the concept where the “transducer becomes part of the signal processing chain” by exploring feedback processes between mechanical and electrical mechanisms that together can enhance peripheral sound processing. This capability is present within a biological acoustic system, namely in the ears of certain moths. That was used as the model of inspiration for a smart acoustic sensor system which provides dynamic adaptation of its frequency response with amplitude and time dependency according to the input signal of interest