Numerical investigation on the cavitating wake flow around a cylinder based on proper orthogonal decomposition

The non-cavitating and cavitating wake flow of a circular cylinder, which contains multiscale vortices, is numerically investigated by Large Eddy Simulation combined with the Schnerr–Sauer cavitation model in this paper. In order to investigate the spatiotemporal evolution of cavitation vortex structures, the Proper Orthogonal Decomposition (POD) method is employed to perform spatiotemporal decomposition on the cylinder wake flow field obtained by numerical simulation. The results reveal that the low-order Proper Orthogonal Decomposition modes correspond to large-scale flow structures with relatively high energy and predominantly single frequencies in both non-cavitating and cavitating conditions. The presence of cavitation bubbles in the flow field leads to a more pronounced deformation of the vortex structures in the low-order modes compared to the non-cavitating case. The dissipation of pressure energy in the cylinder non-cavitating wake occurs faster than the kinetic energy. While in the cavitating wake, the kinetic energy dissipates more rapidly than the pressure energy

Numerical investigation of energy loss distribution in the cavitating wake flow around a cylinder using entropy production method

The wake flow of a circular cylinder is numerically investigated by Large Eddy Simulation (LES) combined with the Schnerr–Sauer cavitation model. By comparing entropy production in the presence or absence of cavitation, the energy loss distribution in the wake flow field of a cylinder is explored, shedding light on the interactions between multiscale vortex systems and cavitation. The comparative results reveal that, under non-cavitating conditions, the energy loss region in the near-wake area is more concentrated and relatively larger. Energy dissipation in the wake flow field occurs in regions characterized by very high velocity gradients, primarily near the upper and lower surfaces of the cylinder near the leading edge. The influence of cavitation bubbles on entropy production is predominantly observed in the trailing-edge region (W1) and the near-wake region (W2). The distribution trends of wall entropy production on the cylinder’s surface are generally consistent in both conditions, with wall entropy production primarily concentrated in regions exhibiting high velocity gradients

Experimental and Numerical Investigation on the Transient Cavitating Flows in a Mixed Flow Pump With Different Number of Blades at Startup

The objective of this paper is to experimentally and numerically investigate the transient cavitation flow during the startup process of mixed flow pump with emphasis on studying the influence of blade numbers. The transient cavitation simulation was studied based on the improved SST k–x turbulence model and the Zwart cavitation model. Firstly, in order to obtain the relationship between transient flow rate and the variation of rotational speed at startup, a theoretical analysis based on the fast transients of centrifugal pump was first applied to mixed flow pump and was verified by the current experiment study. Subsequently, the influence of blade number on the cavitation flow in the startup was studied. It is found that the transient cavitation could be classified into four stages regardless of the number of blades: no cavitation stage, the cavitation growth stage, the cavitation reduction stage and the cavitation stabilization stage. However, the blade number does have an impact on the spatial-temporal evolution of cavitation. More specifically, when the blade number increases, the initial cavitation appeared lately, the coverage area of the triangular cavitation cloud and sheet cavitation both decreased, and the increase in blade number has a better inhibitory effect on the sheet cavitation at the cavitation growth stage and can make sheet cavitation disappear more quickly at the cavitation reduction stage

Research and Design of Fixed Photovoltaic Support Structure Based on SAP2000

In the solar photovoltaic power station project, PV support is one of the main structures, and fixed photovoltaic PV support is one of the most commonly used stents. For the the actual demand in a Japanese photovoltaic power, SAP2000 finite element analysis software is used in this paper, based on Japanese Industrial Standard (JIS C 8955-2011), describing the system of fixed photovoltaic support structure design and calculation method and process. The results show that: (1) according to the general requirements of 4 rows and 5 columns fixed photovoltaic support, the typical permanent load of the PV support is 4679.4 N, the wind load being 1.05 kN/m2, the snow load being 0.89 kN/m2 and the seismic load is 5877.51 N; (2) by theoretical calculation of the two ends extended beam model, the beam span under the rail is determined 2200 mm; (3) by the way of using the single factor experiment, through the calculation and analysis of SAP2000, the three best supporting points of the support of the W stent are determined; (4) by comprehensive simulation, the optimal parameters for the rail, beam, support and bolt are 60× 60× 1.0, 60× 60× 1.0, 40× 50× 2.0, and M10 respectively

Research and Design of Fixed Photovoltaic Support Structure Based on SAP2000

In the solar photovoltaic power station project, PV support is one of the main structures, and fixed photovoltaic PV support is one of the most commonly used stents. For the the actual demand in a Japanese photovoltaic power, SAP2000 finite element analysis software is used in this paper, based on Japanese Industrial Standard (JIS C 8955-2011), describing the system of fixed photovoltaic support structure design and calculation method and process. The results show that: (1) according to the general requirements of 4 rows and 5 columns fixed photovoltaic support, the typical permanent load of the PV support is 4679.4 N, the wind load being 1.05 kN/m2, the snow load being 0.89 kN/m2 and the seismic load is 5877.51 N; (2) by theoretical calculation of the two ends extended beam model, the beam span under the rail is determined 2200 mm; (3) by the way of using the single factor experiment, through the calculation and analysis of SAP2000, the three best supporting points of the support of the W stent are determined; (4) by comprehensive simulation, the optimal parameters for the rail, beam, support and bolt are 60× 60× 1.0, 60× 60× 1.0, 40× 50× 2.0, and M10 respectively

Effect of Type I Diabetes on the Proteome of Mouse Oocytes

Background: Type I diabetes is a global public health concern that affects young people of reproductive age and can damage oocytes, reducing their maturation rate and blocking embryonic development. Understanding the effects of type I diabetes on oocytes is important to facilitate the maintenance of reproductive capacity in female diabetic patients. Methods: To analyze the effects of type I diabetes on mammalian oocytes, protein profile changes in mice with streptozotocin-induced type I diabetes were investigated using proteomic tools; non-diabetic mouse oocytes were used as controls. Immunofluorescence analysis for the spindle and mitochondria of oocytes. Results: We found that type I diabetes severely disturbed the metabolic processes of mouse oocytes. We also observed significant changes in levels of histone H1, H2A/B, and H3 variants in diabetic oocytes (fold change: > 0.4 or Conclusion: Our results indicate that type I diabetes disrupts metabolic processes, spindle formation, mitochondria distribution and modulates epigenetic code in oocytes. Such effects could have a major impact on the reproductive dynamics of female patients with type I diabetes

Data from: Curcumin improves glycolipid metabolism through regulating peroxisome proliferator activated receptor γ signalling pathway in high-fat diet-induced obese mice and 3T3-L1 adipocytes

Curcumin, an active component derived from the Curcuma longa L. which is a traditional Chinese medicine that is widely used for treating metabolic diseases through regulating different molecular pathway. Here, in this study, we aimed to comprehensively investigate the effects of curcumin on glycolipid metabolism in vivo and in vitro and then determine the underlying mechanism. Male C57BL/6J obese mice and 3T3-L1 adipocytes were used in vivo and in vitro study, respectively. Our results demonstrated that treatment with curcumin for 8 weeks decreased body weight, fat mass and serum lipid profiles. Meanwhile, it lowered fasting blood glucose and increased the insulin sensitivity in high-fat diet induced obese mice. In addition, curcumin stimulated lipolysis and improve glycolipid through upregulating the expressions of ATGL, HSL, PPARγ, C/EBPα and PPARα in adipose tissue of the mice. In differentiated 3T3-L1 cells, curcumin reduced glycerol release and increased glucose uptake via upregulating PPARγ and C/EBPα. We concluded that curcumin has potential to improve glycolipid metabolism disorders caused by obesity through regulating PPARγ signaling pathway