Late results of embolization of a portal hepatic vein branches in patients, suffering extended hepatic tumors

Objective. To analyze late results of preoperative  embolization of the portal hepatic vein branches (EPHVB) in patients, suffering extended hepatic tumors and extremely border-like small calculated residual hepatic volume(CRHV). Маterials and methods. From 2004 to 2014 yr the extended hepatic resection (HER) was performed in 285 patients, to whom EPHVB was applied (the main group), аnd in 353 patients as well, but without endovascular preparation (control group). In both groups dynamics of laboratory indices, structure of complications and lethality, late survival were studied. Results. In the main group a trustworthily lower rate of an acute hepatic insufficiency and connected with a lower postoperative lethality - accordingly 2.3 and 4.6%, comparing with a control group - 9.3 and 8.8%, were suggested. The laboratory data dynamics have witnessed a lesser intensiveness of postoperative hepatocytolysis and lesser degree of the hepatic synthetic function lowering in the main group, what have confirmed a better functional adaptation of hepatic residual in patients, to whom preoperative EPHVB was applied. Conclusion. Preoperative EPHVB permits to lower the postoperative complications and lethality rate in patients, suffering hepatic tumors, due to better functional adaptation of hepatic residual

Theory and Applications of X-ray Standing Waves in Real Crystals

Theoretical aspects of x-ray standing wave method for investigation of the real structure of crystals are considered in this review paper. Starting from the general approach of the secondary radiation yield from deformed crystals this theory is applied to different concreat cases. Various models of deformed crystals like: bicrystal model, multilayer model, crystals with extended deformation field are considered in detailes. Peculiarities of x-ray standing wave behavior in different scattering geometries (Bragg, Laue) are analysed in detailes. New possibilities to solve the phase problem with x-ray standing wave method are discussed in the review. General theoretical approaches are illustrated with a big number of experimental results.Comment: 101 pages, 43 figures, 3 table

Morphological features of the uterus in women at different time intervals of the postmortem period as diagnostic criteria for establishing the postmortem interval

The aim is to identify the morphological features of the uterus layers in women at different time intervals of the postmortem period as diagnostic criteria for establishing the postmortem interval. Materials and methods: In the study we used surgical and autopsy material – uterine tissue fragments. All materials were divided into two groups. The 1st group (G 1) included surgical material from women (n=6) who underwent removal of the uterus, or uterus with the appendages due to leiomyoma, uterine prolapse. The 2nd group (G 2) included autopsy material from 42 women with known causes of death and postmortem period (from 24 to 48 hours – 6 cases, from 49 to 72 hours – 7 cases, from 73 to 96 hours – 8 cases, from 97 to 120 hours – 6 cases, from 121 to 144 hours – 8 cases, more than 144 hours – 7 cases). Histological and immunohistochemical study methods were used. Results: A comprehensive morphological study of the women uterus revealed a time-dependent increase of postmortem changes in this organ linked with the increase of postmortem period. In cases of postmortem period duration up to 144 hours, the structural elements of the uterine layers were identified. In cases where the duration of the postmortem period was more than 145 hours, microscopically the uterus was represented by eosinophilic fibrous or dusty masses, the histogenesis of which could not be determined. The processes of autolysis occurred more intensely and faster in the mucous membrane of the uterus, in comparison with the muscular and serous membranes, and in the vessels – in their inner membrane, in comparison with the middle and outer membranes. Autolytic changes in the muscular membrane of the uterus and vascular walls occurred more intensely in muscle fibers compared to connective tissue fibers. Conclusions: The histological and immunohistochemical features of the women uterus at different postmortem periods have a certain forensic medical significance and can be used for establishing the postmortem interval

Final results of the tests on the resistive plate chambers for the ALICE muon arm

Abstract The trigger for the ALICE muon spectrometer will be issued by single-gap, low resistivity bakelite resistive plate chambers (RPCs). The trigger system consists of four 5.5 × 6.5 m 2 RPC planes arranged in two stations, for a total of 72 detectors. One hundred and sixteen detectors have been assembled and tested in Torino. The tests have been performed with the streamer mixture developed for heavy ion data-taking. The tests include: the detection of gas leaks and parasitic currents; the measurement of the efficiency with cosmic rays, with particular regard to the uniformity of the efficiency throughout the whole active surface, with a granularity of about 2 × 2 cm 2 ; the measurement of the dark current and of the mean and localised noise rate. All the RPCs produced have been characterised. Among them, the detectors to be finally installed in ALICE and some spare have been selected; 17% of all the produced detectors have been discarded. A short description of the test set-up is given. The results of the tests are presented, with particular regard to the performance of the selected detectors

Хірургічне лікування гепатобластоми

Objective. To study and improve the results of surgical treatment of children with hepatoblastoma.Materials and methods. The experience of surgical treatment of 90 children with hepatoblastoma is presented: 81 patients who underwent liver resection,and in 9 cases with a nonresectable hepatoblastoma a living-donor liver transplantation was performed.Results. More severe postoperative complications (from ІІІ-b to V degree according to Dindo–Clavien) were observed in the resection group of patients. Postoperative mortality after liver resection was 5% (n=4), and there were no lethal cases after liver transplantation. The 5-year relapse-free survival rate in the transplant group was 69.2% versus 62.5% in the resection group, and the overall survival rate was 75% versus 71%, respectively.Conclusions. Resection and transplantation technologies are effective methods of surgical treatment of hepatoblastoma in children, and in combination with chemotherapy, they can produce a good long-term results. The immediate and long-term results after liver transplantation are better than after liver resection, even though transplantation group patients have a larger tumor lesion in the liver. Liver transplantation is a good treatment option for children with unresectable hepatoblastoma.Цель: исследовать и улучшить результаты хирургического лечения детей с гепатобластомой.Материалы и методы. Проведено хирургическое лечение 90 детей с гепатобластомой: 81 пациенту выполнена резекция печени, а 9 детям с нерезектабельной формой гепатобластомы выполнена трансплантация части печени от живого семейного донора.Результаты. Более тяжелые послеоперационные осложнения (от ІІІ-b до V степени по Dindo–Clavien) наблюдались в резекционной группе пациентов. Послеоперационная летальность после резекции печени составила 5% (n=4), а после трансплантации печени летальных случаев не было. 5-летняя безрецидивная выживаемость в трансплантационной группе составила 69,2% против 62,5% в резекционной группе, а общая выживаемость – 75% против 71% соответственно.Выводы. Резекционные и трансплантационные технологии являются эффективными методами хирургического лечения гепатобластомы у детей и в сочетании с химиотерапией позволяют получить хороший долгосрочный результат. Ближайшие и отдаленные результаты после трансплантации печени лучше, чем после резекции печени, даже несмотря на больший объем опухолевого поражения печени у пациентов трансплантационной группы. Трансплантация печени является единственным эффективным методом хирургического лечения у детей с нерезектабельной гепатобластомой.Мета: дослідити і покращити результати хірургічного лікування дітей з гепатобластомою.Матеріали і методи. Проведено хірургічне лікування 90 дітей з гепатобластомою: 81 пацієнту виконана резекція печінки, а 9 дітям з нерезектабельною формою гепатобластоми виконана трансплантація частини печінки від живого родинного донора.Результати. Більш важкі післяопераційні ускладнення (від ІІІ-b до V ступеня за Dindo–Clavien) спостерігалися у резекційній групі пацієнтів. Післяопераційна летальність після резекції печінки склала 5% (n=4), а після трансплантації печінки летальних випадків не було. 5-річна безрецидивна виживаність у трансплантаційній групі склала 69,2% проти 62,5% у резекційній групі, а загальна виживаність – 75% проти 71% відповідно.Висновки. Резекційні та трансплантаційні технології є ефективними методами хірургічного лікування гепатобластоми у дітей та у поєднанні з хіміотерапією дозволяють отримати хороший довгостроковий результат. Найближчі та віддалені результати після трансплантації печінки кращі, ніж після резекції печінки, незважаючи на більший об’єм пухлинного ураження печінки у пацієнтів трансплантаційної групи. Трансплантація печінки є єдиним ефективним методом хірургічного лікування у дітей з нерезектабельною гепатобластомою

Ageing test of RPC for the Muon Trigger System for the ALICE experiment

The trigger detectors for the Muon Forward Spectrometer of the ALICE experiment will be single gap RPCs with low-resistivity bakelite electrodes. The detector will take data for different colliding systems resulting in a wide range of working conditions and requirements, especially concerning position resolution and lifetime. To this aim we have investigated the possibility to operate the RPCs both in streamer and in saturated avalanche mode with the same FE electronics. The study of the detector performance after long irradiation periods has been carried out at the Gamma Irradiation Facility at CERN with different gas mixtures: a quenched streamer gas mixture (51.5% Ar, 41.3% forane, 7.2% C/sub 2/H/sub 10/ and 1% SF/sub 6/) and a saturated avalanche mixture (88% forane, 10% C/sub 2/H/sub 10/ and 2% SF/sub 6/). We present the results of the ageing test of a final RPC in "ALICE-like" irradiation conditions using the streamer gas mixture and the results of the ageing test of a small prototype with the avalanche gas mixture

R&D on RPC for the Muon Trigger System for the ALICE experiment in view of p-p data taking

présentation F. YermiaALICE (A Large Ion Collider Experiment) is the heavy-ion dedicated experiment at LHC. The Resistive Plate Chamber detector (RPC) with low-resistivity bakelite electrodes was selected for the trigger system of the muon spectrometer. Although the main goal of ALICE is the study of nucleus-nucleus collisions, reference data in p-p interactions will be collected as well. According to the specific aspects of p-p data taking for ALICE and in particular to the ageing requirements, a running mode, referred as highly-saturated avalanche using the same FEE as the one we use for streamer mode was investigated. A detailed study of signal properties was carried out with cosmics rays to get a more precise view of its intrinsic properties (among others the streamer fraction vs. HV). The possibility of detecting avalanche signals with our FEE designed for the streamer mode was successful. Furthermore, tests with muon beam at CERN were carried out with good results: good efficiency, time resolution and cluster size. An analysis of the exhaust gas showed a low HF content: this is an encouraging result in view of long term stability of the detector which is under tes

Final results of the tests on the resistive plate chambers for the ALICE muon arm

The trigger for the ALICE muon spectrometer will be issued by single-gap, low resistivity bakelite resistive plate chambers (RPCs). The trigger system consists of four 5.5 x 6.5 m(2) RPC planes arranged in two stations, for a total of 72 detectors. One hundred and sixteen detectors have been assembled and tested in Torino. The tests have been performed with the streamer mixture developed for heavy ion data-taking. The tests include: the detection of gas leaks and parasitic currents; the measurement of the efficiency with cosmic rays, with particular regard to the uniformity of the efficiency throughout the whole active surface, with a granularity of about 2 x 2 cm(2); the measurement of the dark current and of the mean and localised noise rate. All the RPCs produced have been characterised. Among them, the detectors to be finally installed in ALICE and some spare have been selected; 17% of all the produced detectors have been discarded. A short description of the test set-up is given. The results of the tests are presented, with particular regard to the performance of the selected detectors. (C) 2008 Elsevier B.V. All rights reserved

Final results of the tests on the resistive plate chambers for the ALICE muon arm

International audienceThe trigger for the ALICE muon spectrometer will be issued by single-gap, low resistivity bakelite resistive plate chambers (RPCs). The trigger system consists of four 5.5x6.5 m2 RPC planes arranged in two stations, for a total of 72 detectors. One hundred and sixteen detectors have been assembled and tested in Torino. The tests have been performed with the streamer mixture developed for heavy ion data-taking. The tests include: the detection of gas leaks and parasitic currents; the measurement of the efficiency with cosmic rays, with particular regard to the uniformity of the efficiency throughout the whole active surface, with a granularity of about 2x2 cm2; the measurement of the dark current and of the mean and localised noise rate. All the RPCs produced have been characterised. Among them, the detectors to be finally installed in ALICE and some spare have been selected; 17% of all the produced detectors have been discarded. A short description of the test set-up is given. The results of the tests are presented, with particular regard to the performance of the selected detectors