Dealing With Incomplete Household Panel Data in Inequality Research

Dieser Beitrag ist mit Zustimmung des Rechteinhabers aufgrund einer (DFG geförderten) Allianz- bzw. Nationallizenz frei zugänglich.This publication is with permission of the rights owner freely accessible due to an Alliance licence and a national licence (funded by the DFG, German Research Foundation) respectively.In trying to capture complete within-household heterogeneity, household panel surveys typically try to interview all adult household members. Following from this, such surveys tend to suffer from partial unit nonresponse (PUNR), that is, the nonresponse of at least one member of an otherwise participating household, most likely yielding an underestimation of aggregate household income. Using data from the German Socio-Economic Panel (SOEP), the authors evaluate four different strategies to deal with this phenomenon: (a) ignorance, that is, assuming the missing individual’s income to be zero; (b) adjustment of the equivalence scale to account for differences in household size and composition; (c) elimination of all households observed to suffer PUNR and reweighting of households observed to be at risk of but not affected by PUNR; and (d) longitudinal imputation of the missing income components. The aim of this article is to show how the choice of technique affects substantive results in inequality research. The authors find indications of substantial bias on income inequality and poverty as well as on income mobility

Constraints on decreases in Eta Carinae's mass loss from 3D hydrodynamic simulations of its binary colliding winds

Recent work suggests that the mass-loss rate of the primary star (Eta A) in the massive colliding wind binary Eta Carinae dropped by a factor of 2-3 between 1999 and 2010. We present results from large- (r=1545au) and small- (r=155au) domain, 3D smoothed particle hydrodynamic (SPH) simulations of Eta Car's colliding winds for 3 Eta A mass-loss rates (2.4, 4.8, and 8.5 x 10^-4 M_sun/yr), investigating the effects on the dynamics of the binary wind-wind collision (WWC). These simulations include orbital motion, optically thin radiative cooling, and radiative forces. We find that Eta A's mass-loss rate greatly affects the time-dependent hydrodynamics at all spatial scales investigated. The simulations also show that the post-shock wind of the companion star (Eta B) switches from the adiabatic to the radiative-cooling regime during periastron passage. The SPH simulations together with 1D radiative transfer models of Eta A's spectra reveal that a factor of 2 or more drop in Eta A's mass-loss rate should lead to substantial changes in numerous multiwavelength observables. Recent observations are not fully consistent with the model predictions, indicating that any drop in Eta A's mass-loss rate was likely by a factor < 2 and occurred after 2004. We speculate that most of the recent observed changes in Eta Car are due to a small increase in the WWC opening angle that produces significant effects because our line-of-sight to the system lies close to the dense walls of the WWC zone. A modest decrease in Eta A's mass-loss rate may be responsible, but changes in the wind/stellar parameters of Eta B cannot yet be fully ruled out. We suggest observations during Eta Car's next periastron in 2014 to further test for decreases in Eta A's mass-loss rate. If Eta A's mass-loss rate is declining and continues to do so, the 2014 X-ray minimum should be even shorter than that of 2009.Comment: 38 pages, 25 figures, 1 table. Accepted for publication in MNRA

The Prevalence and Volumetry of Pituitary Cysts in Children with Growth Hormone Deficiency and Idiopathic Short Stature

Background Pituitary cysts have been speculated to cause endocrinopathies. We sought to describe the prevalence and volumetry of pituitary cysts in patients with growth hormone deficiency (GHD) and idiopathic short stature (ISS). Methods Six hundred and eighteen children evaluated for growth failure at the Division of Pediatric Endocrinology at New York Medical College between the years 2002 and 2012, who underwent GH stimulation testing and had a brain magnetic resonance imaging (MRI) prior to initiating GH treatment were randomly selected to be a part of this study. High resolution MRI was used to evaluate the pituitary gland for size and the presence of a cyst. Cyst prevalence, cyst volume and percentage of the gland occupied by the cyst (POGO) were documented. Results Fifty-six patients had a cyst, giving an overall prevalence of 9.1%. The prevalence of cysts in GHD patients compared to ISS patients was not significant (13.5% vs. 5.7%, p=0.46). Mean cyst volume was greater in GHD patients than ISS patients (62.0 mm3 vs. 29.4 mm3, p=0.01). POGO for GHD patients was significantly greater (p=0.003) than for ISS patients (15.3%+/-12.8 vs. 7.1%+/-8.0). Observers were blinded to patient groups. Conclusions GHD patients had a significantly greater volume and POGO compared to ISS patients. This raises the question of whether cysts are implicated in the pathology of growth failure

Eta Carinae long-term variability

We present preliminary results of our analysis on the long-term variations observed in the optical spectrum of the LBV star Eta Carinae. Based on the hydrogen line profiles, we conclude that the physical parameters of the primary star did not change in the last 15 years.Comment: 2 pages, 1 figure, IAUS 272 - Active OB Stars: Structure, Evolution, Mass Loss and Critical Limit

Development of Joint Manufacturing and In-Line Metrology System for the Patterning of 3D Holographic Structures in Roll-to-Roll Processes

Roll-to-roll (R2R) fabrication at the micro and nano scales promises to increase manufacturing throughput and reduce unit cost while providing avenues for unique product applications. By exploring the potential of creating 3D structures with a single lithography step and being able to confirm success in-situ, existing multilayer patterning error can be mitigated, since 3D features would be created in one step rather than many. This paper demonstrates steps being taken to combine a R2R 3D nanolithography tool and an atomic force microscopy (AFM)- based in-line metrology tool into a functional system for patterning precise 3D structures. An existing manufacturing system will be adapted to pattern complex structures with a flexible PDMS mask currently being proven on stationary substrates. Modifications to the AFM system will include a focus on imaging patterns with varying mechanical properties and tailoring the system to include gathering mechanical information as well as imaging. By mapping surface features, the AFM tool will identify surface imperfections and predict failure modes occurring within the 3D structure.Mechanical Engineerin

Kassiopeia: A Modern, Extensible C++ Particle Tracking Package

The Kassiopeia particle tracking framework is an object-oriented software package using modern C++ techniques, written originally to meet the needs of the KATRIN collaboration. Kassiopeia features a new algorithmic paradigm for particle tracking simulations which targets experiments containing complex geometries and electromagnetic fields, with high priority put on calculation efficiency, customizability, extensibility, and ease of use for novice programmers. To solve Kassiopeia's target physics problem the software is capable of simulating particle trajectories governed by arbitrarily complex differential equations of motion, continuous physics processes that may in part be modeled as terms perturbing that equation of motion, stochastic processes that occur in flight such as bulk scattering and decay, and stochastic surface processes occuring at interfaces, including transmission and reflection effects. This entire set of computations takes place against the backdrop of a rich geometry package which serves a variety of roles, including initialization of electromagnetic field simulations and the support of state-dependent algorithm-swapping and behavioral changes as a particle's state evolves. Thanks to the very general approach taken by Kassiopeia it can be used by other experiments facing similar challenges when calculating particle trajectories in electromagnetic fields. It is publicly available at https://github.com/KATRIN-Experiment/Kassiopei

Microglia-mediated demyelination protects against CD8+ T cell-driven axon degeneration in mice carrying PLP defects

Axon degeneration and functional decline in myelin diseases are often attributed to loss of myelin but their relation is not fully understood. Perturbed myelinating glia can instigate chronic neuroinflammation and contribute to demyelination and axonal damage. Here we study mice with distinct defects in the proteolipid protein 1 gene that develop axonal damage which is driven by cytotoxic T cells targeting myelinating oligodendrocytes. We show that persistent ensheathment with perturbed myelin poses a risk for axon degeneration, neuron loss, and behavioral decline. We demonstrate that CD8(+) T cell-driven axonal damage is less likely to progress towards degeneration when axons are efficiently demyelinated by activated microglia. Mechanistically, we show that cytotoxic T cell effector molecules induce cytoskeletal alterations within myelinating glia and aberrant actomyosin constriction of axons at paranodal domains. Our study identifies detrimental axon-glia-immune interactions which promote neurodegeneration and possible therapeutic targets for disorders associated with myelin defects and neuroinflammation. Demyelination is often suggested to cause axonal degeneration. Here, the authors study mice carrying distinct PLP defects and reveal how persistent ensheathment with perturbed myelin poses a risk for CD8+T cell-driven axon loss and behavioral decline

Ablation of atrial fibrillation with the Epicor system: a prospective observational trial to evaluate safety and efficacy and predictors of success

<p>Abstract</p> <p>Background</p> <p>High intensity focused ultrasound (HIFU) energy has evolved as a new surgical tool to treat atrial fibrillation (AF). We evaluated safety and efficacy of AF ablation with HIFU and analyzed predictors of success in a prospective clinical study.</p> <p>Methods</p> <p>From January 2007 to June 2008, 110 patients with AF and concomitant open heart surgery were enrolled into the study. Main underlying heart diseases were aortic valve disease (50%), ischemic heart disease (48%), and mitral valve disease (18%). AF was paroxysmal in 29%, persistent in 31%, and long standing persistent in 40% of patients, lasting for 1 to 240 months (mean 24 months). Mean left atrial diameter was 50 ± 7 mm. Each patient underwent left atrial ablation with the Epicor system prior to open heart surgery. After surgery, the patients were treated with amiodarone and coumadin for 6 months. Follow-up studies including resting ECG, 24 h Holter ECG, and echocardiography were obtained at 6 and 12 months.</p> <p>Results</p> <p>All patients had successful application of the system on the beating heart prior to initiation of extracorporeal circulation. On average, 11 ± 1 ultrasound transducer elements were used to create the box lesion. The hand-held probe for additional linear lesions was employed in 83 cases. No device-related deaths occurred. Postoperative pacemaker insertion was necessary in 4 patients. At 6 months, 62% of patients presented with sinus rhythm. No significant changes were noted at 12 months. Type of AF and a left atrial diameter > 50 mm were predictors for failure of AF ablation.</p> <p>Conclusion</p> <p>AF ablation with the Epicor system as a concomitant procedure during open heart surgery is safe and acceptably effective. Our overall conversion rate was lower than in previously published reports, which may be related to the lower proportion of isolated mitral valve disease in our study population. Left atrial size may be useful to determine patients who are most likely to benefit from the procedure.</p