40 research outputs found
AN ANALYSIS OF CONSUMER PERCEPTIONS OF FRESH FISH AND SEAFOOD IN THE DELMARVA REGION
Consumer/Household Economics,
In and around: identifying predictors of theft within and near to major mass underground transit systems
This article identifies factors that encourage or reduce pick-pocketing at underground rail stations through a case study analysis of the London Underground. Negative binomial Poisson regression models found predictor variables of pick-pocketing selected from the internal characteristics of stations and features of their nearby surroundings. Factors that increased risk were those associated with greater congestion inside stations including lifts, waiting rooms and fewer platforms; and increased levels of accessibility near stations, more paths and roads. Features that reduced risk were those likely to encourage detection and guardianship; stations with more personal validators, staffing levels and shop rentals; and the presence of more domestic buildings nearby. Station type was also influential; those that were âattractorsâ of crime and those frequently used by tourists were at greater risk. The findings suggest a transmission of theft risk between the internal settings of underground stations and their nearby surroundings
Psip1/p52 regulates posterior Hoxa genes through activation of lncRNA Hottip
Long noncoding RNAs (lncRNAs) have been implicated in various biological functions including the regulation of gene expression, however, the functionality of lncRNAs is not clearly understood and conflicting conclusions have often been reached when comparing different methods to investigate them. Moreover, little is known about the upstream regulation of lncRNAs. Here we show that the short isoform (p52) of a transcriptional co-activatorâPC4 and SF2 interacting protein (Psip1), which is known to be involved in linking transcription to RNA processing, specifically regulates the expression of the lncRNA Hottipâlocated at the 5â end of the Hoxa locus. Using both knockdown and knockout approaches we show that Hottip expression is required for activation of the 5â Hoxa genes (Hoxa13 and Hoxa10/11) and for retaining Mll1 at the 5â end of Hoxa. Moreover, we demonstrate that artificially inducing Hottip expression is sufficient to activate the 5â Hoxa genes and that Hottip RNA binds to the 5â end of Hoxa. By engineering premature transcription termination, we show that it is the Hottip lncRNA molecule itself, not just Hottip transcription that is required to maintains active expression of posterior Hox genes. Our data show a direct role for a lncRNA molecule in regulating the expression of developmentally-regulated mRNA genes in cis
NEW FOOD PRODUCTS: INNOVATION, IMPROVEMENT, OR IMITATION?
Researchers have little understanding of what lies beneath the increased numbers and declining "innovativeness" of new food products. This paper investigates product innovation by focusing on both market- and firm-level relationships. Structural data is compared with innovation trends to determine possible associations. A mail questionnaire of 27 food manufacturing firms investigates the issues of strategy, practices and performance. The food manufacturing industries reflect the conventional wisdom that larger firms in concentrated markets invest more in product innovation efforts, but do not contribute proportionately more to innovative output. The declining "innovativeness" of food products results from emphasis on developing product improvements and imitations
NEW FOOD PRODUCTS: INNOVATION, IMPROVEMENT, OR IMITATION?
Researchers have little understanding of what lies beneath the increased numbers and declining "innovativeness" of new food products. This paper investigates product innovation by focusing on both market- and firm-level relationships. Structural data is compared with innovation trends to determine possible associations. A mail questionnaire of 27 food manufacturing firms investigates the issues of strategy, practices and performance. The food manufacturing industries reflect the conventional wisdom that larger firms in concentrated markets invest more in product innovation efforts, but do not contribute proportionately more to innovative output. The declining "innovativeness" of food products results from emphasis on developing product improvements and imitations.Research and Development/Tech Change/Emerging Technologies,