Our Accumulation Addiction: The Harm of Overconsumption and Rehabilitation Treatments for our Minds and the Environment

In the same way an addict rationalizes using their substance, environmental degradation has been framed as an unfortunate side effect of our inevitable progress towards a predetermined future. These tendencies are justified using a constructed narrative built on cultural techniques and global systems of oppression, conditioning our minds to be in a constant state of desire. By framing consumerism as an addiction, this analysis questions the source of our unbridled dysregulated desire, investigates potential harm reduction addiction interventions and applies them on a global scale as a treatment for our consumption craving. This path away from consumption dependency engages the difficulties of living simply, our fear of scarcity, and a critical long-term approach to pleasure in an attempt to imagine a future in which we consciously rehabilitate our relationship with the environment by healing our bodies and minds.https://digitalcommons.slc.edu/undergrad_selectedworks/1014/thumbnail.jp

Global Delivery of Human Papillomavirus Vaccines

Worldwide, cervical cancer is the fourth most common cancer among women, with over half a million women diagnosed with cervical cancer in 2012. Human papillomavirus (HPV) vaccination, if broadly implemented, has the potential to significantly reduce global rates of morbidity and mortality associated with cervical and other HPV-related cancers. Over 100 countries around the world have licensed HPV vaccines. As of February, 2015, there were an estimated 80 national HPV immunization programs and 37 pilot programs, including many implemented in low- and middle-income countries. In this article, global implementation of HPV vaccination programs is discussed, including successes and ongoing challenges. Issues such as vaccine financing and different approaches to HPV vaccine delivery are presented

NASA/MOD Operations Impacts from Shuttle Program

Operations plays a pivotal role in the success of any human spaceflight program. This paper will highlight some of the core tenets of spaceflight operations from a systems perspective and use several examples from the Space Shuttle Program to highlight where the success and safety of a mission can hinge upon the preparedness and competency of the operations team. Further, awareness of the types of operations scenarios and impacts that can arise during human crewed space missions can help inform design and mission planning decisions long before a vehicle gets into orbit. A strong operations team is crucial to the development of future programs; capturing the lessons learned from the successes and failures of a past program will allow for safer, more efficient, and better designed programs in the future. No matter how well a vehicle is designed and constructed, there are always unexpected events or failures that occur during space flight missions. Preparation, training, real-time execution, and troubleshooting are skills and values of the Mission Operations Directorate (MOD) flight controller; these operational standards have proven invaluable to the Space Shuttle Program. Understanding and mastery of these same skills will be required of any operations team as technology advances and new vehicles are developed. This paper will focus on individual Space Shuttle mission case studies where specific operational skills, techniques, and preparedness allowed for mission safety and success. It will detail the events leading up to the scenario or failure, how the operations team identified and dealt with the failure and its downstream impacts. The various options for real-time troubleshooting will be discussed along with the operations team final recommendation, execution, and outcome. Finally, the lessons learned will be summarized along with an explanation of how these lessons were used to improve the operational preparedness of future flight control teams

Diversified Long-term Growth: A Winning Portfolio for Mountain Research

The diversity of membership in the Mountain Research Initiative (MRI) is one of its principal assets. This diversity is now exemplified in MRI's Science Leadership Council, composed of active mountain researchers from around the world and charged with leading the MRI. The first major task of the Science Leadership Council was the development of MRI's Strategic Plan, a document that makes explicit what has been implicit for years in MRI's activities. The Strategic Plan provides a common vision, a focused mission, a set of guiding principles, long-term goals, and more specific and measurable objectives. It provides the framework for MRI's most recent grant application to the Swiss National Science Foundation and similarly guides the progress of the MRI toward its vision

Accounting for changing temperature patterns increases historical estimates of climate sensitivity

Eight atmospheric general circulation models (AGCMs) are forced with observed historical (1871–2010) monthly sea surface temperature and sea ice variations using the Atmospheric Model Intercomparison Project II data set. The AGCMs therefore have a similar temperature pattern and trend to that of observed historical climate change. The AGCMs simulate a spread in climate feedback similar to that seen in coupled simulations of the response to CO2 quadrupling. However, the feedbacks are robustly more stabilizing and the effective climate sensitivity (EffCS) smaller. This is due to a pattern effect, whereby the pattern of observed historical sea surface temperature change gives rise to more negative cloud and longwave clear‐sky feedbacks. Assuming the patterns of long‐term temperature change simulated by models, and the radiative response to them, are credible; this implies that existing constraints on EffCS from historical energy budget variations give values that are too low and overly constrained, particularly at the upper end. For example, the pattern effect increases the long‐term Otto et al. (2013, https://doi.org/10.1038/ngeo1836) EffCS median and 5–95% confidence interval from 1.9 K (0.9–5.0 K) to 3.2 K (1.5–8.1 K

Electrospun aligned tacrolimus-loaded polycaprolactone biomaterials for peripheral nerve repair

Background: Efficacious repair of peripheral nerve injury is an unmet clinical need. The implantation of biomaterials containing neurotrophic drugs at the injury site could promote nerve regeneration and improve outcomes for patients. Materials & methods: Random and aligned electrospun poly-ε-caprolactone scaffolds containing encapsulated tacrolimus were fabricated, and the gene expression profile of Schwann cells (SCs) cultured on the surface was elucidated. On aligned fibers, the morphology of SCs and primary rat neurons was investigated. Results: Both scaffold types exhibited sustained release of drug, and the gene expression of SCs was modulated by both nanofibrous topography and the presence of tacrolimus. Aligned fibers promoted the alignment of SCs and orientated outgrowth from neurons. Conclusion: Electrospun PCL scaffolds with tacrolimus hold promise for the repair of peripheral nerve injury

Everything You Need to Know about Grants: Beginning, Middle and End

“Everything You Need to Know about Grants: Beginning, Middle and End” was a 90-minute session presented at the Society of California Archivists Annual General Meeting in Berkeley, CA, on April 13, 2013. As a part of the archival community, many of us know that grants are an excellent way to reduce backlogs or accomplish projects we don\u27t have the resources to tackle. However, what many of us may not know is how much work goes into successfully implementing and completing a grant. The purpose of this session was to assemble a group of individuals who have been involved in various aspects of the grant application and implementation process to share their expertise with the archival community. The session utilized a question and answer format with a moderator asking pre-arranged questions. This article provides excerpts from the panelists’ responses

Development and preliminary testing of the psychosocial adjustment to hereditary diseases scale

Background: The presence of Lynch syndrome (LS) can bring a lifetime of uncertainty to an entire family as members adjust to living with a high lifetime cancer risk. The research base on how individuals and families adjust to genetic-linked diseases following predictive genetic testing has increased our understanding of short-term impacts but gaps continue to exist in knowledge of important factors that facilitate or impede long-term adjustment. The failure of existing scales to detect psychosocial adjustment challenges in this population has led researchers to question the adequate sensitivity of these instruments. Furthermore, we have limited insight into the role of the family in promoting adjustment. Methods: The purpose of this study was to develop and initially validate the Psychosocial Adjustment to Hereditary Diseases (PAHD) scale. This scale consists of two subscales, the Burden of Knowing (BK) and Family Connectedness (FC). Items for the two subscales were generated from a qualitative data base and tested in a sample of 243 participants from families with LS. Results: The Multitrait/Multi-Item Analysis Program-Revised (MAP-R) was used to evaluate the psychometric properties of the PAHD. The findings support the convergent and discriminant validity of the subscales. Construct validity was confirmed by factor analysis and Cronbach’s alpha supported a strong internal consistency for BK (0.83) and FC (0.84). Conclusion: Preliminary testing suggests that the PAHD is a psychometrically sound scale capable of assessing psychosocial adjustment. We conclude that the PAHD may be a valuable monitoring tool to identify individuals and families who may require therapeutic interventions