Parametric instabilities in the LCGT arm cavity

We evaluated the parametric instabilities of LCGT (Japanese interferometric gravitational wave detector project) arm cavity. The number of unstable modes of LCGT is 10-times smaller than that of Advanced LIGO (U.S.A.). Since the strength of the instabilities of LCGT depends on the mirror curvature more weakly than that of Advanced LIGO, the requirement of the mirror curvature accuracy is easier to be achieved. The difference in the parametric instabilities between LCGT and Advanced LIGO is because of the thermal noise reduction methods (LCGT, cooling sapphire mirrors; Advanced LIGO, fused silica mirrors with larger laser beams), which are the main strategies of the projects. Elastic Q reduction by the barrel surface (0.2 mm thickness Ta$_2$O$_5$) coating is effective to suppress instabilities in the LCGT arm cavity. Therefore, the cryogenic interferometer is a smart solution for the parametric instabilities in addition to thermal noise and thermal lensing.Comment: 6 pages,3 figures. Amaldi7 proceedings, J. Phys.: Conf. Ser. (accepted

Parametric instabilities and their control in advanced interferometer GW detectors

A detailed simulation of Advanced LIGO test mass optical cavities shows that parametric instabilities will excite acoustic modes in the test masses in the frequency range 28-35 kHz and 64-72 kHz. Using nominal Advanced LIGO optical cavity parameters with fused silica test masses, parametric instability excites 7 acoustic modes in each test mass, with parametric gain R up to 7. For the alternative sapphire test masses only 1 acoustic mode is excited in each test mass with R ~ 2. Fine tuning of the test mass radii of curvature cause the instabilities to sweep through various modes with R as high as ~2000. Sapphire test mass cavities can be tuned to completely eliminate instabilities using thermal g-factor tuning with negligible degradation of the noise performance. In the case of fused silica test mass, instabilities can be minimized but not eliminated.Comment: 5 pages, 4 figure

Beam Scraping for LHC Injection

Operation of the LHC will require injection of very high intensity beams from the SPS to the LHC. Fast scrapers have been installed and will be used in the SPS to detect and remove any existing halo before beams are extracted, to minimize the probability for quenching of superconducting magnets at injection in the LHC. We briefly review the functionality of the scraper system and report about measurements that have recently been performed in the SPS on halo scraping and re-population of tails

Distribution of Salmonella enterica isolates from human cases in Italy, 1980 to 2011

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Treatment of ongoing autoimmune encephalomyelitis with activated B-cell progenitors maturing into regulatory B cells.

The influence of signals perceived by immature B cells during their development in bone marrow on their subsequent functions as mature cells are poorly defined. Here, we show that bone marrow cells transiently stimulated in vivo or in vitro through the Toll-like receptor 9 generate proB cells (CpG-proBs) that interrupt experimental autoimmune encephalomyelitis (EAE) when transferred at the onset of clinical symptoms. Protection requires differentiation of CpG-proBs into mature B cells that home to reactive lymph nodes, where they trap T cells by releasing the CCR7 ligand, CCL19, and to inflamed central nervous system, where they locally limit immunopathogenesis through interleukin-10 production, thereby cooperatively inhibiting ongoing EAE. These data demonstrate that a transient inflammation at the environment, where proB cells develop, is sufficient to confer regulatory functions onto their mature B-cell progeny. In addition, these properties of CpG-proBs open interesting perspectives for cell therapy of autoimmune diseases

Three-mode opto-acoustic parametric interactions with coupled cavity

We theoretically analyze three-mode opto-acoustic parametric interactions in a coupled Fabry-Perot cavity, where one acoustic mode interacts with two optical modes. We show explicitly that extra degrees of freedom in a coupled cavity allow explorations of both parametric instability and cooling regimes with high parametric gain in a single table top experiment. This work can motivate experimental realizations of the three-mode parametric instability which might be an issue in next-generation gravitational-wave detectors with high optical-power cavities, helping in the development of better models, and in developing techniques for controls. In addition, we show that the same scheme can be implemented in the resolved-sideband acoustic-mode cooling.Comment: 15 pages, 7 figure

Real time- and control software for the new orbit measurement system for the CERN SPS

The 240 channel SPS Orbit acquisition system is implemented on a PowerPC under the LynxOS operating system, making use of multi threaded real-time capabilities. The acquired data is transferred efficiently by DMA via the PCI bus into the main memory. System configuration aspects were implemented in a Broker architecture, where individual threads communicate with an Oracle database and the acquisition systems. This Broker hides the implementation details of the front-end systems. A versatile configuration client is provided in Java, to provide both local graphical user interfaces and remote WWW access using a dedicated gateway to the SL equipment layer. The timing diagnostics of the acquisition system are provided in a LabView application integrating oscilloscope control and channel multiplex control. This paper describes in detail the technical solutions implemented and reports on the arguments, which have led to particular choices