Modal expansion for the 2D Green's function in a non-orthogonal coordinates system.

We present an efficient modal method to calculate the two-dimensional Green's function for electromagnetics in curvilinear coordinates. For this purpose the coordinate transformation based differential method, introduced for the numerical analysis of surface-relief gratings, is directly used with perfectly matched layers (PMLs). The covariant formalism Maxwell's equations, very convenient for the non-orthogonal coordinates formulation, also gives an unified analysis of PMLs. Numerical results for a line source placed above a perfectly conducting corrugated surface are presented

Synthesis and cellular uptake of superparamagnetic dextran-nanoparticles with porphyrinic motifs grafted by esterification

International audienceThis paper describes new superparamagnetic nanoparticles bearing dextran-grafted porphyrins with effective cellular uptake properties. They average 110 nm in diameter and are composed of a 5 nm iron oxide core coated with protoporphyrin grafted dextrans. These particles show good magnetic properties, are avidly incorporated into cultured cancer cell lines, and thus present a great potential for cellular imaging and photodynamic therapy applications

One-Pot Silver Nanoring Synthesis

Silver colloidal nanorings have been synthesized by reducing silver ions with NaBH4 in trisodium citrate buffers. pH increase, by addition of NaOH, was used to speed up reduction reaction. The UV–vis absorption spectra of resulting silver nanorings showed two peaks accounting for transverse and longitudinal surface plasmon resonance, at ≈400 nm, and between 600 and 700 nm, respectively. The shapes of these silver nanoparticles (nanorings) depended on AgNO3/NaBH4 ratio, pH and reaction temperature. Particles were analysed by transmission electron microscopy, scanning electron microscopy and X-ray diffraction. A reaction pathway is proposed to explain silver nanoring formation

Alpi e patrimonio industriale : cultura e memoria, XIX-XX sec. = Alpes et patrimoine industriel : culture et mémoire, XIXe-XXe siècles = Alpen und industrielles Erbe : Kultur und Erinnerung, 19.-20. Jahrhundert

Cosa racconta il passato industriale delle Alpi? I vari studi contenuti in questo volume si interrogano su differenze e similitudini della patrimonializzazione dell’industria rispetto all’evoluzione della memoria e della costruzione patrimoniale promossa in questi ultimi decenni nel mondo alpino

Characterisation of Innate Fungal Recognition in the Lung

The innate recognition of fungi by leukocytes is mediated by pattern recognition receptors (PRR), such as Dectin-1, and is thought to occur at the cell surface triggering intracellular signalling cascades which lead to the induction of protective host responses. In the lung, this recognition is aided by surfactant which also serves to maintain the balance between inflammation and pulmonary function, although the underlying mechanisms are unknown. Here we have explored pulmonary innate recognition of a variety of fungal particles, including zymosan, Candida albicans and Aspergillus fumigatus, and demonstrate that opsonisation with surfactant components can limit inflammation by reducing host-cell fungal interactions. However, we found that this opsonisation does not contribute directly to innate fungal recognition and that this process is mediated through non-opsonic PRRs, including Dectin-1. Moreover, we found that pulmonary inflammatory responses to resting Aspergillus conidia were initiated by these PRRs in acidified phagolysosomes, following the uptake of fungal particles by leukocytes. Our data therefore provides crucial new insights into the mechanisms by which surfactant can maintain pulmonary function in the face of microbial challenge, and defines the phagolysosome as a novel intracellular compartment involved in the innate sensing of extracellular pathogens in the lung

Modélisation et étude numérique des transferts en milieux fissurés

L'ETUDE DES RESERVOIRS FISSURES REPRESENTE ACTUELLEMENT UN ASPECT FONDAMENTAL DE L'INDUSTRIE PETROLIERE. CES RESERVOIRS A HAUT RENDEMENT SE CARACTERISENT PAR L'EXTREME COMPLEXITE DE LEUR STRUCTURE INTERNE ET PAR LA COEXISTENCE DE MILIEUX DE CARACTERISTIQUES TRES DIFFERENTES. POUR SIMULER LES ECOULEMENTS DANS DE TELS MILIEUX, LES INGENIEURS UTILISENT DES MODELES PARTICULIERS BASES SUR UNE IDEALISATION (DITE DE WARREN & ROOT) ET UN MODELE DOUBLE-MILIEU. DANS CE MODELE, L'ECHANGE MATRICE-FISSURE EST REPRESENTEE PAR UNE EQUATION DE TRANSFERT QUASI-STATIONNAIRE FAISANT INTERVENIR UN COEFFICIENT D'ECHANGE. LE CHOIX DE CE FACTEUR D'ECHANGE EST ENCORE SUJET A CONTROVERSE. EN OUTRE, DE NOMBREUX PHENOMENES PHYSIQUES SONT NEGLIGES ET LES PROCESSUS RESTENT ENCORE MAL COMPRIS. AFIN D'AMELIORER CES MODELES, UN SIMULATEUR FOURNISSANT DES SOLUTIONS DE REFERENCE EST NECESSAIRE. C'EST POURQUOI NOUS PROPOSONS ICI DE SIMULER A L'ECHELLE FINE LES ECOULEMENTS MONOPHASIQUES ET DIPHASIQUES DANS LA MATRICE ET LES FISSURES. DANS CE BUT NOUS AVONS DEVELOPPE UNE METHODE PARTICULIERE APPELEE METHODE DES ELEMENTS FISSURES. CELLE-CI REPOSE SUR UN MAILLAGE PARTICULIER DU MILIEU (ELEMENTS LINEAIRES POUR LES FISSURES, TRIANGLES POUR LA MATRICE) ET SUR DES SCHEMAS DE TYPE VOLUMES FINIS APPROPRIES. CETTE THESE PRESENTE LE DEVELOPPEMENT DETAILLE DE CETTE NOUVELLE METHODE NUMERIQUE. A L'ISSU DE CE TRAVAIL, UN CODE DE CALCUL A ETE REALISE ET DES SIMULATIONS ONT PU ETRE EFFECTUEES. ELLES NOUS ONT PERMIS DE REALISER DES COMPARAISONS ENTRE DIVERS MODELES DOUBLE-MILIEU. L'EXPLOITATION DE CE CODE NOUS A AINSI CONDUIT A MENER UNE REFLEXION SUR LE CHOIX DU FACTEUR D'ECHANGE, DETERMINANT POUR LA FORMULATION DU MODELE DOUBLE-MILIEU.BORDEAUX1-BU Sciences-Talence (335222101) / SudocLILLE1-BU (590092102) / SudocSudocFranceF

La fatigue (conseils à l officine et cas particulier du Syndrome de Fatigue Chronique)

ANGERS-BU Médecine-Pharmacie (490072105) / SudocSudocFranceF