Epidemiology of classic psychedelic substances: results from a Norwegian internet convenience sample

ObjectiveIn recent years, there has been a renewed interest in investigating the use of classic psychedelics such as psilocybin and lysergic acid diethylamide (LSD) in the treatment of mental disorders and substance use disorders. However, knowledge about the epidemiology of classic psychedelics in the Nordic countries is limited.MethodsWe recruited adult, Norwegian participants who have had a memorable experience after taking a classic psychedelic substance. They filled in an anonymous internet survey with 119 items covering matters related to recreational use of psychedelics using a secure, web-based application. Data are presented by using descriptive statistics (frequencies, means, and standard deviations).ResultsWe recruited 841 participants, 770 (72% male; 88% 45 years or younger) of which were included in the data analysis. The intentions behind taking the psychedelic substance were mainly recreational (46.1%) or therapeutic (42.3%). Most participants reported that their most memorable experience was with psilocybin. As in modern era clinical trials, most participants were well-prepared before, did processing during, and did integration work after the experience, whereas only a minority were supported by a therapist. Self-perceived symptoms of various mental disorders and substance use disorders were prevalent in the sample. Most subjects reported improvements in their condition. Although adverse reactions were usually mild and short-lived, 4.2% lasted for 1 year or more. Persisting flashbacks were present for a year or more among 2.9% of the participants.ConclusionIn this cross-sectional sample of Norwegian, self-selecting adults, we shed light on what characterizes the most memorable experience with a classic psychedelic substance, including short- and long-term risks and benefits. For the most part, the psychedelic experience led to improvements in self-perceived symptoms of mental disorders and substance use disorders. However, a small subset experienced persisting adverse reactions

Characterisation of barley resistance to rhynchosporium on chromosome 6HS

Key Message: Major resistance gene to rhynchosporium, Rrs18, maps close to the telomere on the short arm of chromosome 6H in barley. Rhynchosporium or barley scald caused by a fungal pathogen Rhynchosporium commune is one of the most destructive and economically important diseases of barley in the world. Testing of Steptoe × Morex and CIho 3515 × Alexis doubled haploid populations has revealed a large effect QTL for resistance to R. commune close to the telomere on the short arm of chromosome 6H, present in both populations. Mapping markers flanking the QTL from both populations onto the 2017 Morex genome assembly revealed a rhynchosporium resistance locus independent of Rrs13 that we named Rrs18. The causal gene was fine mapped to an interval of 660 Kb using Steptoe × Morex backcross 1 S₂ and S₃ lines with molecular markers developed from Steptoe exome capture variant calling. Sequencing RNA from CIho 3515 and Alexis revealed that only 4 genes within the Rrs18 interval were transcribed in leaf tissue with a serine/threonine protein kinase being the most likely candidate for Rrs18.Max Coulter, Bianca Büttner, Kerstin Hofmann, Micha Bayer, Luke Ramsay, Günther Schweizer, Robbie Waugh, Mark E. Looseley, Anna Avrov

Downhole cutting tool design concept for use with the AWS “Driller”

Master's thesis in Offshore technologyProduction tubing cutting operations is getting more and more common in the North Sea; this is a product of an increasing number of Plug and Abandonment operations and re-completions of old wells. The most common method of cutting production tubing has for a long time been explosive cutters. These cutters are relatively simple in use, cheap to produce and quite reliable. However, explosive cutters are as the name implies containing explosives. Explosive handling offshore should be kept to a minimum since the consequence of an explosion during handling of these types of cutters would most likely be fatal. Together with the other disadvantages of explosive cutters a non-explosive cutter should always be considered for the job. The goal with this thesis was to design a non-explosive cutting tool that could be powered by an already existing Electro-Mechanical AWS tool. A part of this task it has been to present some of the already existing cutting tools on the market. Further basic well design is described to give a better understanding of why downhole cutting tools are needed. Different completion parts are described together with some examples of why the production tubing needs to be cut and removed. An interview with 3 different oil companies has also been conducted. This interview indicates that these three operator companies are positive with running Electro-Mechanical cutting tools in the future. There is also a chapter in this thesis where it is discussed how condition monitoring can be implemented in the between-job maintenance of the cutting concept. These techniques could be used by any other tool suitable for condition monitoring. It is in this thesis concluded that this design concept can be a developed into a functioning cutting tool, if an appropriate centralization mechanism is developed. It does also conclude that condition monitoring should be implemented in the between run maintenance of downhole tools suitable for condition monitoring

Øvelseshefte : våre viktigste grasarter i eng, beiter og plener

PK 23/24. Eng- og beitedyrking. Øvelseshefte - beskrivelse av morfologiske karakterer til hjelp ved artsbestemmelse under øvelsene i kurset. Opptrykk 198

Forelesninger om grasarter

For kurset i engvekster. Utgave fra januar 1976

Frøblandinger til eng og beite

Notater til forelesninger om eng- og beitedyrking, PK23/24. Utgitt 1981, revidert 199

HoNOS in Quality Development Processes in Mental Health Care

This is a project collection header for various studies examining the use of HoNOS in mental health car