1,057 research outputs found
Automated implementation of rule-based expert systems with neural networks for time-critical applications
In fault diagnosis, control and real-time monitoring, both timing and accuracy are critical for operators or machines to reach proper solutions or appropriate actions. Expert systems are becoming more popular in the manufacturing community for dealing with such problems. In recent years, neural networks have revived and their applications have spread to many areas of science and engineering. A method of using neural networks to implement rule-based expert systems for time-critical applications is discussed here. This method can convert a given rule-based system into a neural network with fixed weights and thresholds. The rules governing the translation are presented along with some examples. We also present the results of automated machine implementation of such networks from the given rule-base. This significantly simplifies the translation process to neural network expert systems from conventional rule-based systems. Results comparing the performance of the proposed approach based on neural networks vs. the classical approach are given. The possibility of very large scale integration (VLSI) realization of such neural network expert systems is also discussed
Zero-Voltage and Zero-Current Switching Buck-Boost Converter for PV Applications
A ZVS and ZCS buck boost converter is presented for PV panel applications. The salient points are that all the switching devices are under zero-current switching during turn-on and zero-voltage switching during turn-off. The active switches in the converter undergo zero-capacitive turn-on losses unlike switches in other soft-switched topologies. The switches do not experience any over voltage/over current stress proportional to load as in resonant converters. This soft-switching technique can also be applied to other classical switched mode power converters. A detailed analysis of the converter under steady state is discussed and simulation results obtained are presented
Modeling a IF double sampling bandpass switched capacitor ΣΔ ADC with a symmetric noise transfer function for WiMAX/WLAN
4G technology aims to revolutionize private and professional communication with its ubiquity and high-speed transmission (averaging 100Mbps). WiMAX and WLAN are two of the high speed access technologies to be used in the 4G mobile communication. Apropos to their high bandwidths, oversampling converters, e.g.ΣΔ ADCs, used for these standards would entail high levels of power consumption. Double sampling technique used in ΣΔ ADCs help in reducing the power consumption, since the actual sampling rate is only half the sampling frequency required to achieve a target resolution. But for conventional modulators, with low pass noise transfer functions (NTF), this benefit is hampered by the introduction of folded noise due to the mismatch of sampling capacitances. This paper presents a novel method of designing IF bandpass switched capacitor (SC)ΣΔ modulators with symmetric NTFs. Such a bandpass NTF is formulated with its center frequency at one-fourth the effective sampling frequency. The symmetricity ensures that the folded noise is `noise-shaped' along with the quantization noise. The idea is verified with a discrete time bandpass ΣΔ modulator modeled using Simulink®, including various nonlinearities, viz. clock jitter, opampnonidealities, and capacitive mismatch effects owing to double sampling and use of a multibitquantizer. Behavioral simulations of the proposed non-ideal model for WiMAX and WLAN, with a bandwith of 10MHz and 11MHz, respectively, achieved a peak resolution greater than 10 bits for each of the standards
Ab initio molecular dynamics using density based energy functionals: application to ground state geometries of some small clusters
The ground state geometries of some small clusters have been obtained via ab
initio molecular dynamical simulations by employing density based energy
functionals. The approximate kinetic energy functionals that have been employed
are the standard Thomas-Fermi along with the Weizsacker correction
and a combination . It is shown that the functional
involving gives superior charge densities and bondlengths over the
standard functional. Apart from dimers and trimers of Na, Mg, Al, Li, Si,
equilibrium geometries for and clusters have also
been reported. For all the clusters investigated, the method yields the ground
state geometries with the correct symmetries with bondlengths within 5\% when
compared with the corresponding results obtained via full orbital based
Kohn-Sham method. The method is fast and a promising one to study the ground
state geometries of large clusters.Comment: 15 pages, 3 PS figure
Possible large-N fixed-points and naturalness for O(N) scalar fields
We try to use scale-invariance and the large-N limit to find a non-trivial 4d
O(N) scalar field model with controlled UV behavior and naturally light scalar
excitations. The principle is to fix interactions by requiring the effective
action for space-time dependent background fields to be finite and
scale-invariant when regulators are removed. We find a line of non-trivial UV
fixed-points in the large-N limit, parameterized by a dimensionless coupling.
They reduce to classical la phi^4 theory when hbar -> 0. For hbar non-zero,
neither action nor measure is scale-invariant, but the effective action is.
Scale invariance makes it natural to set a mass deformation to zero. The model
has phases where O(N) invariance is unbroken or spontaneously broken. Masses of
the lightest excitations above the unbroken vacuum are found. We derive a
non-linear equation for oscillations about the broken vacuum. The interaction
potential is shown to have a locality property at large-N. In 3d, our
construction reduces to the line of large-N fixed-points in |phi|^6 theory.Comment: 23 page
An orbital-free molecular dynamics study of melting in K_20, K_55, K_92, K_142, Rb_55 and Cs_55 clusters
The melting-like transition in potasium clusters K_N, with N=20, 55, 92 and
142, is studied by using an orbital-free density-functional constant-energy
molecular dynamics simulation method, and compared to previous theoretical
results on the melting-like transition in sodium clusters of the same sizes.
Melting in potasium and sodium clusters proceeds in a similar way: a surface
melting stage develops upon heating before the homogeneous melting temperature
is reached. Premelting effects are nevertheless more important and more easily
established in potasium clusters, and the transition regions spread over
temperature intervals which are wider than in the case of sodium. For all the
sizes considered, the percentage melting temperature reduction when passing
from Na to K clusters is substantially larger than in the bulk. Once those two
materials have been compared for a number of different cluster sizes, we study
the melting-like transition in Rb_55 and Cs_55 clusters and make a comparison
with the melting behavior of Na_55 and K_55. As the atomic number increases,
the height of the specific heat peaks decreases, their width increases, and the
melting temperature decreases as in bulk melting, but in a more pronounced way.Comment: LaTeX file. 6 pages with 17 pictures. Final version with minor
change
Effect of tcdR Mutation on Sporulation in the Epidemic Clostridium difficile Strain R20291
Citation: Girinathan, B. P., Monot, M., Boyle, D., McAllister, K. N., Sorg, J. A., Dupuy, B., & Govind, R. (2017). Effect of tcdR Mutation on Sporulation in the Epidemic Clostridium difficile Strain R20291. Msphere, 2(1), 14. doi:10.1128/mSphere.00383-16Clostridium difficile is an important nosocomial pathogen and the leading cause of hospital-acquired diarrhea. Antibiotic use is the primary risk factor for the development of C. difficile-associated disease because it disrupts normally protective gut flora and enables C. difficile to colonize the colon. C. difficile damages host tissue by secreting toxins and disseminates by forming spores. The toxin-encoding genes, tcdA and tcdB, are part of a pathogenicity locus, which also includes the tcdR gene that codes for TcdR, an alternate sigma factor that initiates transcription of tcdA and tcdB genes. We created a tcdR mutant in epidemic-type C. difficile strain R20291 in an attempt to identify the global role of tcdR. A site-directed mutation in tcdR affected both toxin production and sporulation in C. difficile R20291. Spores of the tcdR mutant were more heat sensitive than the wild type (WT). Nearly 3-fold more taurocholate was needed to germinate spores from the tcdR mutant than to germinate the spores prepared from the WT strain. Transmission electron microscopic analysis of the spores also revealed a weakly assembled exosporium on the tcdR mutant spores. Accordingly, comparative transcriptome analysis showed many differentially expressed sporulation genes in the tcdR mutant compared to the WT strain. These data suggest that regulatory networks of toxin production and sporulation in C. difficile strain R20291 are linked with each other. IMPORTANCE C. difficile infects thousands of hospitalized patients every year, causing significant morbidity and mortality. C. difficile spores play a pivotal role in the transmission of the pathogen in the hospital environment. During infection, the spores germinate, and the vegetative bacterial cells produce toxins that damage host tissue. Thus, sporulation and toxin production are two important traits of C. difficile. In this study, we showed that a mutation in tcdR, the toxin gene regulator, affects both toxin production and sporulation in epidemic-type C. difficile strain R20291
The Cone Phase of Liquid Crystals: Triangular Lattice of Double-Tilt Cylinders
We predict the existence of a new defect-lattice phase near the nematic -
smectic-C (NC) transition. This tilt- analogue of the blue phase is a lattice
of double-tilt cylinders. We discuss the structure and stability of the cone
phase. We suggest that many `nematics' exhibiting short range layering and tilt
order may in fact be in the molten cone phase, which is a line liquid.Comment: 4 Pages, 3 Figure
Two-soliton solution for the derivative nonlinear Schr\"odinger equation with nonvanishing boundary conditions
An explicit two-soliton solution for the derivative nonlinear Schr\"odinger
equation with nonvanishing boundary conditions is derived, demonstrating
details of interactions between two bright solitons, two dark solitons, as well
as one bright soliton and one dark soliton. Shifts of soliton positions due to
collisions are analytically obtained, which are irrespective of the bright or
dark characters of the participating solitons.Comment: 11 pages, 4 figures. Phys. Lett. A 2006 (in press
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