Dynamics of doublon-holon pairs in Hubbard two-leg ladders

The dynamics of holon-doublon pairs is studied in Hubbard two-leg ladders using the time-dependent Density Matrix Renormalization Group method. We find that the geometry of the two-leg ladder, that is qualitatively different from a one-dimensional chain due to the presence of a spin-gap, strongly affects the propagation of a doublon-holon pair. Two distinct regimes are identified. For weak inter-leg coupling, the results are qualitatively similar to the case of the propagation previously reported in Hubbard chains, with only a renormalization of parameters. More interesting is the case of strong inter-leg coupling where substantial differences arise, particularly regarding the double occupancy and properties of the excitations such as the doublon speed. Our results suggest a connection between the presence of a spin gap and qualitative changes in the doublon speed, indicating a weak coupling between the doublon to magnetic excitations.Comment: 8 pages, 9 figures. Published versio

Large-Scale Monte Carlo Study of a Realistic Lattice Model for Ga_(1-x)Mn_xAs

The properties of Mn-doped GaAs are studied at several doping levels and hole compensations, using a real-space Hamiltonian on an fcc lattice that reproduces the valence bands of undoped GaAs. Large-scale Monte Carlo (MC) simulations on a Cray XT3 supercomputer, using up to a thousand nodes, were needed to make this effort possible. Our analysis considers both the spin-orbit interaction and the random distribution of the Mn ions. The hopping amplitudes are functions of the GaAs Luttinger parameters. At the coupling J~1.2eV deduced from photoemission experiments, the MC Curie temperature and the shape of the magnetization curves are in agreement with experimental results for annealed samples. Although there are sizable differences with mean-field predictions, the system is found to be closer to a hole-fluid regime than to localized carriers

Inaccuracy of Death Certificate Diagnosis of Tuberculosis and Potential Underdiagnosis of TB in a Region of High HIV Prevalence

Despite the South African antiretroviral therapy rollout, which should reduce the incidence of HIV-associated tuberculosis (TB), the number of TB-attributable deaths in KwaZuluNatal (KZN) remains high. TB is often diagnosed clinically, without microbiologic confirmation, leading to inaccurate estimates of TB-attributed deaths. This may contribute to avoidable deaths, and impact population-based TB mortality estimates. Objectives. (1) To measure the number of cases with microbiologically confirmed TB in a retrospective cohort of deceased inpatients with TB-attributed hospital deaths. (2) To estimate the rates of multi-drug resistant (MDR) and extensively drug resistant (XDR) TB in this cohort. Results. Of 2752 deaths at EDH between September 2006 and March 2007, 403 (15%) were attributed to TB on the death certificate. 176 of the TB-attributed deaths (44%) had a specimen sent for smear or culture; only 64 (36%) had a TB diagnosis confirmed by either test. Of the 39 culture-confirmed cases, 27/39 (69%) had fully susceptible TB and 27/39 (69%) had smear-negative culture-positive TB (SNTB). Two patients had drug monoresistance, three patients had MDR-TB, and one had XDR-TB. Conclusions. Most TB-attributed deaths in this cohort were not microbiologically confirmed. Of confirmed cases, most were smear-negative, culture positive and were susceptible to all first line drugs

Hydrothermal Unit Commitment with Deterministic Optimization : Generation and Transmission Including Pumped Storage Units

This work presents a novel approach for solving the short-therm scheduling of hydro-thermal power generation, including pumped storage systemsand transmission constraints. The problem addressed is known as Security Constrained Unit Commitment (SCUC). Pumped Storage Units (PSUs) are importantin electric systems during the off-peak and the peak demand periods, providing economic and technical benefits. Linear aproximations are applied to nonlinear equations of this kind of mathematical problems which are: fuel cost functions, generation-discharge curves of PSUs and transmission constraints modeled with Alternating Current power flow model. Thus, MILP models are presented for the problem addessed. To prove the efficiency of the proposed models, two systems with PSUs will be tested: a modified 6-bus and the IEEE 31-bus power system. Results show that the proposed MILP models allow: modeling the SCUC problem more realistically, obtaining feasible solutions within efficient computational times, and reaching production cost savings up to almost 20% compared to power systems that lack capacities to pumping water. Several indicators obtained from results are presented through graphs, as a tool for improving operation and maintenance of power systems. The analysis of these indicators and the graphic interpretation allow to identify and classify critical parts of systems as well as to make recommendations about future system improvements.Sociedad Argentina de Informática e Investigación Operativ

Cryptographic requirements for chaotic secure communications

In recent years, a great amount of secure communications systems based on chaotic synchronization have been published. Most of the proposed schemes fail to explain a number of features of fundamental importance to all cryptosystems, such as key definition, characterization, and generation. As a consequence, the proposed ciphers are difficult to realize in practice with a reasonable degree of security. Likewise, they are seldom accompanied by a security analysis. Thus, it is hard for the reader to have a hint about their security. In this work we provide a set of guidelines that every new cryptosystems would benefit from adhering to. The proposed guidelines address these two main gaps, i.e., correct key management and security analysis, to help new cryptosystems be presented in a more rigorous cryptographic way. Also some recommendations are offered regarding some practical aspects of communications, such as channel noise, limited bandwith, and attenuation.Comment: 13 pages, 3 figure

Estudio del mojado y caracterización superficial por microscopía de barrido laser confocal de chapas de madera obtenidas por desenrollo

El objetivo de este trabajo fue estudiar las propiedades superficiales de chapas obtenidas por desenrollo de cinco especies de maderas duras: okume, ayous, chopo, fromager y eucalipto, y comparar el comportamiento de ambas caras de las chapas. Se han determinado los ángulos de contacto de equilibrio y se ha determinado la energía libre superficial de la madera así como sus componentes polar y dispersa. Asimismo, mediante microscopía de barrido láser confocal se ha evaluado la rugosidad superficial. La energía libre superficial osciló entre 49-64 mJ/m2 y disminuyó en el orden okume > fromager > chopo > ayous ~ eucalipto, lo que indica un descenso de la capacidad de mojado en ese orden. El okume con el mayor valor de la energía libre superficial y los menores valores del ángulo de contacto de equilibrio se confirmó como la especie con las mejores propiedades de mojado, siendo además la que presentó los mayores valores de los parámetros de rugosidad superficial. Comparando las propiedades superficiales para las dos caras de las chapas se encontró que dependieron de la especie, pero en general, con la excepción de la rugosidad, las diferencias no fueron muy significativas siendo los mayores cambios para las chapas de okume que presentaron un mejor mojado en su cara interior. AbstractThe aim of this work was to study the surface properties of rotary-peeled veneers of five species of hardwoods: okume, ayous, poplar, fromager and eucalyptus and to compare the behavior of both sides of the veneers. The equilibrium contact angles were determined together with the wood surface free energy and its polar and disperse components. Additionally, surface roughness was evaluated using confocal laser scanning microscopy. Surface free energy ranged from 49-64 mJ/m2 and decreased in the order okume> fromager> poplar> eucalyptus ~ ayous, indicating a decrease in wettability in that order. Okume wood with the highest value of the surface free energy and the lowest values of the equilibrium contact angle was confirmed as the species with the best wetting properties, and also presented the highest values of surface roughness parameters. In general, there were not significant differences between the properties of both sides of the veneers, except for roughness. The largest differences were obtained for okume veneers whose interior side showed higher wettability

Risk of unintentional injuries in children and adolescents with ADHD and the impact of ADHD medications: protocol for a systematic review and meta-analysis

Introduction Attention-deficit hyperactivity disorder (ADHD) has been related to increased rates of unintentional injuries. However, the magnitude of the effect and to which extent variables such as sex, age or comorbidity can influence this relationship is unknown. Additionally, and importantly, it is unclear if, and to which degree, ADHD medications can decrease the number of unintentional injuries. Due to the amount of economic and social resources invested in the treatment of injuries, filling these gaps in the literature is highly relevant from a public health standpoint. Here, we present a protocol for a systematic review and meta-analysis to estimate the relationship between ADHD and unintentional injuries and assess the impact of pharmacological treatment for ADHD Methods and analysis We will combine results from 114 bibliographic databases for studies relating ADHD and risk of injuries. Bibliographic searches and data extraction will be carried out independently by two researchers. The studies’ risk of bias will be assessed using the Newcastle-Ottawa Scale. Articles reporting ORs or HRs of suffering an injury in ADHD compared with controls (or enough data to calculate them) will be combined using Robust Variance Estimation, a method that permits to include multiple non-independent outcomes in the analysis. All analyses will be carried out in Stata. Age, sex and comorbid conduct disorders will be considered as potential causes of variance and their effect analysed through meta-regression and subgroup analysis. Sensitivity analyses will exclude articles with longer follow-ups, non-stringent definitions of ADHD or controls and statistically uncontrolled/controlled outcomes. Studies implementing a self-controlled case series methodology to investigate if ADHD drugs reduce the risk of injuries will be combined with a generalised linear mixed model using the Poisson distribution and a log link function

Risk of unintentional injuries in children and adolescents with ADHD and the impact of ADHD medications: A systematic review and meta-analysis

A systematic review with meta-analyses was performed to: 1) quantify the association between ADHD and risk of unintentional physical injuries in children/adolescents (¿risk analysis¿); 2) assess the effect of ADHD medications on this risk (¿medication analysis¿). We searched 114 databases through June 2017. For the risk analysis, studies reporting sex-controlled odds ratios (ORs) or hazard ratios (HRs) estimating the association between ADHD and injuries were combined. Pooled ORs (28 studies, 4,055,620 individuals without and 350,938 with ADHD) and HRs (4 studies, 901,891 individuals without and 20,363 with ADHD) were 1.53 (95% CI = 1.40,1.67) and 1.39 (95% CI = 1.06,1.83), respectively. For the medication analysis, we meta-analysed studies that avoided the confounding-by-indication bias [four studies with a self-controlled methodology and another comparing risk over time and groups (a ¿difference in differences¿ methodology)]. The pooled effect size was 0.879 (95% CI = 0.838,0.922) (13,254 individuals with ADHD). ADHD is significantly associated with an increased risk of unintentional injuries and ADHD medications have a protective effect, at least in the short term, as indicated by self-controlled studies

Polyfunctional T cell responses in children in early stages of chronic Trypanosoma cruzi infection contrast with monofunctional responses of long-term infected adults

Background: Adults with chronic Trypanosoma cruzi exhibit a poorly functional T cell compartment, characterized by monofunctional (IFN-γ-only secreting) parasite-specific T cells and increased levels of terminally differentiated T cells. It is possible that persistent infection and/or sustained exposure to parasites antigens may lead to a progressive loss of function of the immune T cells. Methodology/Principal Findings: To test this hypothesis, the quality and magnitude of T. cruzi-specific T cell responses were evaluated in T. cruzi-infected children and compared with long-term T. cruzi-infected adults with no evidence of heart failure. The phenotype of CD4+ T cells was also assessed in T. cruzi-infected children and uninfected controls. Simultaneous secretion of IFN-γ and IL-2 measured by ELISPOT assays in response to T. cruzi antigens was prevalent among T. cruzi-infected children. Flow cytometric analysis of co-expression profiles of CD4+ T cells with the ability to produce IFN-γ, TNF-α, or to express the co-stimulatory molecule CD154 in response to T. cruzi showed polyfunctional T cell responses in most T. cruzi-infected children. Monofunctional T cell responses and an absence of CD4+TNF-α+-secreting T cells were observed in T. cruzi-infected adults. A relatively high degree of activation and differentiation of CD4+ T cells was evident in T. cruzi-infected children. Conclusions/Significance: Our observations are compatible with our initial hypothesis that persistent T. cruzi infection promotes eventual exhaustion of immune system, which might contribute to disease progression in long-term infected subjects.Fil: Albareda, María Cecilia. Dirección Nacional de Instituto de Investigación. Administración Nacional de Laboratorio e Instituto de Salud. Instituto Nacional de Parasitología; Argentina. Consejo Nacional de Investigaciones Científicas y Técnicas; Argentina. Provincia de Buenos Aires. Ministerio de Salud. Hospital Interzonal de Agudos "Eva Perón"; ArgentinaFil: de Rissio, Ana María. Dirección Nacional de Instituto de Investigación. Administración Nacional de Laboratorio e Instituto de Salud. Instituto Nacional de Parasitología; ArgentinaFil: Tomas, Gonzalo. Dirección Nacional de Instituto de Investigación. Administración Nacional de Laboratorio e Instituto de Salud. Instituto Nacional de Parasitología; ArgentinaFil: Serjan, Alicia. Gobierno de la Ciudad de Buenos Aires. Hospital General de Agudos "Juan A. Fernández"; ArgentinaFil: Alvarez, María Gabriela. Provincia de Buenos Aires. Ministerio de Salud. Hospital Interzonal de Agudos "Eva Perón"; ArgentinaFil: Viotti, Rodolfo Jorge. Provincia de Buenos Aires. Ministerio de Salud. Hospital Interzonal de Agudos "Eva Perón"; ArgentinaFil: Fichera, Laura Edith. Dirección Nacional de Instituto de Investigación. Administración Nacional de Laboratorio e Instituto de Salud. Instituto Nacional de Parasitología; Argentina. Consejo Nacional de Investigaciones Científicas y Técnicas; ArgentinaFil: Esteva, Mónica Inés. Dirección Nacional de Instituto de Investigación. Administración Nacional de Laboratorio e Instituto de Salud. Instituto Nacional de Parasitología; ArgentinaFil: Potente, Daniel Fernando. Provincia de Buenos Aires. Ministerio de Salud. Hospital Interzonal de Agudos "Eva Perón"; ArgentinaFil: Armenti, Alejandro. Provincia de Buenos Aires. Ministerio de Salud. Hospital Interzonal de Agudos "Eva Perón"; ArgentinaFil: Tarleton, Rick L.. University of Georgia; Estados UnidosFil: Laucella, Susana Adriana. Dirección Nacional de Instituto de Investigación. Administración Nacional de Laboratorio e Instituto de Salud. Instituto Nacional de Parasitología; Argentina. Consejo Nacional de Investigaciones Científicas y Técnicas; Argentin