Pleistocene-Holocene P. nigra traces on tufa archives in the Northern Meseta of the Iberian Peninsula

Molds preserved on travertines constitute exceptional species-informative material to reconstruct past vegetation. These are common on the High Ebro region. Here, the fluvial system erosion and karstification of the Mesozoic limestone since the Late Tertiary, origins extensive travertine complexes like the one studied in Tubilla del Agua (Burgos). In this site, three different travertine complexes are observed. The older one is represented by two disconnected edifices incised by the Valoria river. The age of this structure is established between > 300,000 and 240,000 yr BP, as from the U/Th dating on its base and top. The subsequent incision lasted until at least 90,000 yr BP, when another edifice erected upstream on the older one. The second travertine group comprises three platforms aged 60,000 yr BP the lower one, and 18,000 yr BP the middle one. The third travertine group is a lake-barrier complex 12,000 yr BP old, on which Tubilla del Agua was built, and a stratified travertine body that covers the valley bottom 10,000 to 2700 cal yr BP old. Some of the ages of the oldest travertines, and the most modern ones, coincide with the principal travertine formation cycles described by Durán (1996) for Spain. The matrix of precipitated calcium carbonate of all these complexes are rich in plant remain molds (mosses, stems, leaves, cones) of the surrounding flora. Pinus nigra Arnold cone molds have been localized and identified by comparative morphology studies. These remains are of high valuable information about the Pleistocene and Holocene presence of this taxon, in a site where no natural presence can be found today. This work was funded by project CGL2008-06005

Electrical and magnetic properties of FM/MgO/FM (FM = Co90Fe10, Fe20Ni80) heterostructures

In this paper we present the development and characterization of FM/MgO/FM (FM = Co90Fe10, Fe20Ni80) heterostructures. The magnetic order of the structures, magnetic anisotropy and interlayer exchange coupling were characterized by magnetization measurements. The influence of the substrate temperature during growth on the magnetic properties and topographical features of the bottom electrode was also explored. Higher values of the coercive field were achieved increasing the substrate temperature during deposition of the bottom electrode. Patterned magnetic tunnel junctions were grown on Si(1 0 0) and MgO(1 0 0). The junctions consist of square pillars with different areas (1600, 625, 100 and 25 μm2) fabricated by optical lithography. I(V) curves obtained with conducting atomic force microscopy of the patterned junctions were performed at room temperature in order to explore the reproducibility of the transport properties of the insulating barrier. The results show a more insulating behavior of the junctions grown on Si(1 0 0), with very good control and a high reproducibility of the transport properties of the MgO insulating barrier.Fil: Aviles Felix, Luis Steven. Consejo Nacional de Investigaciones Científicas y Técnicas. Centro Científico Tecnológico Conicet - Patagonia Norte; Argentina. Comisión Nacional de Energía Atómica. Centro Atómico Bariloche; Argentina. Comisión Nacional de Energía Atómica. Gerencia del Área de Energía Nuclear. Instituto Balseiro; ArgentinaFil: Gonzalez Sutter, Jesus Ignacio. Consejo Nacional de Investigaciones Científicas y Técnicas. Centro Científico Tecnológico Conicet - Patagonia Norte; Argentina. Comisión Nacional de Energía Atómica. Centro Atómico Bariloche; Argentina. Comisión Nacional de Energía Atómica. Gerencia del Área de Energía Nuclear. Instituto Balseiro; ArgentinaFil: Gomez, Javier Enrique. Consejo Nacional de Investigaciones Científicas y Técnicas. Centro Científico Tecnológico Conicet - Patagonia Norte; Argentina. Comisión Nacional de Energía Atómica. Centro Atómico Bariloche; Argentina. Comisión Nacional de Energía Atómica. Gerencia del Área de Energía Nuclear. Instituto Balseiro; ArgentinaFil: Sirena, Martin. Consejo Nacional de Investigaciones Científicas y Técnicas. Centro Científico Tecnológico Conicet - Patagonia Norte; Argentina. Comisión Nacional de Energía Atómica. Centro Atómico Bariloche; Argentina. Comisión Nacional de Energía Atómica. Gerencia del Área de Energía Nuclear. Instituto Balseiro; Argentin

Macrorremains evidence of anthropogenic recession of Pinus nigra Aiton in Northern Spain

The natural forest landscape of the Duero Basin in Spain¿s Northern Meseta is now reduced to small masses, its demise largely owed to the intense agricultural and stock-raising use made of its lands. The composition of the scant natural masses suggests that formations dominated by broadleaved species once occupied a much greater area. This idea has led to the believe that pine trees have few place within the natural dynamics of this area (Carrión and Fernández, 2009). However, P. pinaster Aiton and P.pinea L. on low-land sandy areas, P. sylvestris L. and P.uncinata Ramond ex DC on mountain high areas have been demonstrated to have played an important role during the Holocene (Franco et al., 2005; Rubiales et al., 2010). The abundant plant remains and moulds of pine wood and cones found on Northern Meseta peat bogs and travertines, now demonstrate its presence on mid-lands during the Quaternary until the last millenni

In vitro caecal fermentation in Cuino Mexican and Hairless Mexican pigs supplemented with chromium

Los cerdos Pelón Mexicano (CPM) y Cuino Mexicano (CCM) son nativos de México. El cromo (Cr) es un nutriente esencial en el metabolismo de carbohidratos, lípidos y aminoácidos, pero su efecto en cerdos a nivel de la fermentación cecal se desconoce. El objetivo fue evaluar la fermentación cecal in vitro y el nitrógeno (N) digestible en el intestino del CPM y CCM, mediante la adición de Cr en la dieta. Se sacri caron 48 cerdas con peso vivo de 104 0.5 kg, 24 por cada genotipo, de las cuales se colectó contenido cecal e ileal. Las muestras de contenido ileal se incubaron in vitro y se evalúo la fermentación (ml gas g1 MS) a las 3, 6, 9, 12, 24 y 36 h y la composición química. El diseño experimental fue completamente al azar con arreglo factorial 2 x 2. No hubo diferencias entre genotipos (P>0.1), la dieta sin cromo mostró mayor fermentación (p 0.1) por efecto del genotipo o dieta. Hubo mayor contenido de N total y N-NH3 en íleon para el genotipo CCM (p 0.05) en el contenido de N-total, N-NH3 y N aminoacidico a nivel cecal. Se concluye que los CCM mostraron un mayor contenido de N-Total y N-NH3 en íleon que los CPM; el Cr dietario no in uyó en el contenido de nitrógeno en intestinos delgado y grueso, ni en la fermentación cecal microbiana de los cerdos

Characteristics of 107 Spanish healthcare registries and evaluation of the utilization thereof

BACKGROUND: The information concerning the currently existing healthcare registries in our country is not readily accessible, is scarce and some are not well-known, possibly being underused in comparison to their many potential uses. This study is aimed at evaluating the characteristics of the Spanish Healthcare registries and the utilization thereof, especially in Healthcare technology assessment. METHODS: Descriptive, cross-sectional study of the Spanish Healthcare registries within the 1997-2002 period. These registries were identified by means ofa bibliographic databases search and by way of a survey of Scientific Societies and Central and Autonomic Healthcare Administration. Another bibliographic databases search was conducted of the publications which use data from the healthcare registries included and have been evaluated by applying the scientific evidence quality criteria. RESULTS: A total of 107 healthcare registries were identified, most of which of local or regional coverage (71%), preferably were under Autonomic government authority (64.5%). The areas showing the largest number of registries identified were those related to death statistics (16.8%) and cancer (15.9%). A total of 298 publications were retrieved which analyze data produced by the registries identified, most of which are devoted to the study of the frequency and distribution of the events recorded (58.1%) and less frequently to the conducting of healthcare technology assessment studies (24.4%). CONCLUSIONS: The critical evaluation of the publications made it possible to identify some elements related to the analysis methodology and design which would heighten the quality of the healthcare technology assessment. Healthcare registries in Spain have developed recently and to differing degrees. Important areas without any records and improvement elements related to the use of healthcare registries for healthcare technology assessment were detected. It would be advisable to avail of a register of registries which would provide relevant, up-dated information thereon. Fundamento:La información sobre los registros sanitarios exis-tentes en nuestro país es poco accesible y escasa y algunos son pococonocidos, pudiendo estar infrautilizados en relación con sus múlti-ples usos potenciales. El objetivo de este trabajo es evaluar las carac-terísticas de los Registros Sanitarios españoles y su utilización, espe-cialmente en Evaluación de Tecnologías Sanitarias.Métodos:Estudio descriptivo transversal de los Registros Sanita-rios españoles entre 1997 y 2002. La identificación de los registros serealizó a través de búsqueda bibliográfica y mediante encuesta a Socie-dades Científicas y Administración sanitaria central y autonómica. Seha realizado una búsqueda bibliográfica específica de las publicacio-nes que utilizan datos de los registros sanitarios incluidos y se han eva-luado aplicando los criterios de calidad de la evidencia científica.Resultados:Se han identificado 107 registros sanitarios, prefe-rentemente de cobertura local o regional (71%) y dependientes en sumayoría de la Administración autonómica (64,5%). Las áreas conmayor número de registros identificados corresponden a la mortali-dad (16,8%) y al cáncer (15,9%). Se han recuperado 298 publicacio-nes que analizan datos producidos por los registros identificados, delas que la mayoría se dedican al estudio de la frecuencia y distribuciónde los eventos registrados (58,1%) y con menor frecuencia a la reali-zación de estudios de evaluación de tecnologías sanitarias (24,4%).Conclusiones: La evaluación crítica de las publicaciones ha per-mitido identificar algunos elementos relacionados con el diseño y lametodología de análisis que incrementarían la calidad de los estudiosde evaluación de tecnologías sanitarias.Los registros sanitarios enEspaña han tenido un desarrollo desigual y reciente. Se han detecta-do áreas relevantes sin registros y elementos de mejora relacionadoscon la utilización de los registros sanitarios para estudios de evalua-ción de tecnologías sanitarias. Sería recomendable contar con unregistro de registros que proporcionara información relevante yactualizada sobre los mismo

New Evidence on Regucalcin, Body Composition, and Walking Ability Adaptations to Multicomponent Exercise Training in Functionally Limited and Frail Older Adults

Background: Regucalcin, or senescence marker protein-30 (SMP30), is a Ca2+-binding protein with multiple functions reported in the literature. Physical exercise has been shown to improve aging markers; nevertheless, SMP30 in humans has not been extensively researched. Older adults experience a decline in functional capacity and body composition. The purpose of this study was to examine the effects of a multicomponent training (MCT) program on SMP30 and its regulation of walking ability and body composition in functionally limited, frail, and pre-frail older adults. Methods: A total of 34 older adults (aged 80.3 +/- 6.1 years) were divided into an intervention group (IG = 20) and control group (CG = 14). The IG performed a supervised MCT (strength, endurance, balance, coordination, and flexibility) program for 6 months, 3 days per week, whereas the CG continued their normal lives without any specific physical training. SMP30 was analyzed in plasma after 3 and 6 months of MCT, while some physical fitness variables (Timed Up and Go (TUG) and 6-min walk test (6MWT)) and body composition (fat mass and lean mass) were measured at baseline, as well as after 3 months and 6 months of MCT. Results: No significant changes were observed in SPM30 between the IG (877.5 a.u. to 940.5 a.u., respectively) and CG (790.4 a.u. to 763.8 a.u., respectively). Moreover, no SMP30 differences were found between groups after 3 and 6 months of MCT. The IG improved significantly in the 6MWT after 3 months (472.2 +/- 84.2 m) compared to baseline (411.2 +/- 75.2 m). The IG also significantly enhanced their TUG performance after 3 months (7.6 +/- 1.6 s) and 6 months (7.3 +/- 1.8 s) of training compared to baseline (9.3 +/- 3.2 s) (all, p < 0.001). There were no significant differences in body composition between the IG and CG through the 6 months of MCT. Conclusions: The present study suggests that MCT did not change SMP30 levels from 3 to 6 months, where there were changes in neither walking ability nor body composition; however, MCT was effective in improving 6MWT and TUG performance from baseline to 3 months

Huellas de la presencia pasada de pinares montanos en la submeseta norte de la Península Ibérica: Tubilla del Lago y Tubilla del Agua

Se presentan los resultados de los estudios de macrorrestos e impresiones vegetales hallados en dos localidades de la submeseta norte de la Península Ibérica. Los troncos y piñas subfósiles extraídos en las obras de la turbera de Tubilla del Lago (Burgos), así como el molde de piña encontrado en los travertinos de Tubilla del Agua (Burgos), han sido identificados mediante morfología comparada con apoyo de la microtomía en el caso de las maderas. Los restos subfósiles han sido datados mediante 14 C mientras que la antigüedad del molde ha sido deducida por su posición en el edificio travertínico y la edad del mismo, en base al conocimiento de la cronología de la génesis de este tipo de estructuras. Los resultados indican la presencia holocena de Pinus nigra Arnold en ambas localidades. Estas evidencias se suman a otras paleobotánicas, históricas y toponímicas ya existentes, que reflejan una mayor extensión de esta especie en la submeseta norte anterior a la generalización de la alteración antrópica del paisaj

Simodont: Creación de biblioteca virtual mediante la incorporación de nuevos casos de cariology en entorno simulado

Depto. de Odontología Conservadora y PrótesisFac. de OdontologíaFALSEsubmitte

Agrárpiaci Jelentések, Baromfi

Amerikai Egyesült Államok agrárminisztériumának (USDA) májusban megjelent jelentése szerint az USA csirkehústermelése 4,6 millió tonna körül alakult 2017 első negyedévében, ami 2 százalékkal haladta meg az előző év azonos időszakának kibocsátását. Az Európai Bizottság adatai alapján 2017 első 20 hetében 178 euró/100 kilogramm volt az egész csirke uniós átlagára, kismértékben csökkent az előző év hasonló időszakának átlagárához viszonyítva. Magyarországon a vágócsirke élősúlyos termelői ára (245,9 forint/kilogramm) 4,3 százalékkal volt alacsonyabb 2017 20. hetében az egy évvel korábbinál

Nuclear factor IA is expressed in astrocytomas and is associated with improved survival

Nuclear factor IA (NFIA) is a transcription factor that specifies glial cell identity and promotes astrocyte differentiation during embryonic development. Its expression and function in gliomas are not known. Here, we examined NFIA protein expression in gliomas and its association with clinical outcome in pediatric malignant astrocytomas. We analyzed expression of NFIA by immunohistochemistry in 88 existing glioma specimens from Childrens Hospital Los Angeles and the University of Southern California. Association between NFIA expression and progression-free survival (PFS) was examined in high-grade astrocytomas for which clinical data were available (n = 23, all children). NFIA was highly expressed in astrocytomas of all grades, but only in a minority of cells in oligodendroglial tumors. NFIA was expressed on a higher percentage of tumor cells in low-grade astrocytomas (91 ± 5% and 77 ± 14% in World Health Organization [WHO] I and II, respectively) compared with high-grade astrocytomas (48 ± 18% and 37 ± 16% in WHO III and IV, respectively; P < .001, low- vs high-grade astrocytomas). There was a significant association between NFIA expression and PFS in children with astrocytoma WHO grade III or IV (Cox regression P = .019; logrank trend test for NFIA tertiles P = .0040 and NFIA quartiles P = .014). The association was not consistently significant in this small series of patients after adjustment was made for WHO grade III or IV. This is the first study to demonstrate expression of NFIA protein in astrocytomas and its association with grades of astrocytoma and PFS, suggesting that NFIA may play a role in astrocytoma biology