Dormancy in Deinococcus sp. UDEC-P1 as a survival strategy to escape from deleterious effects of carbon starvation and temperature

Dormancy is characterized by low metabolism and absence of protein synthesis and cellular division enabling bacterial cells to survive under stress. The aim was to determine if carbon starvation and low temperature are factors that modify the proportion of dormant/active cells in Deinococcus sp. UDEC-P1. By flow cytometry, RedoxSensor Green (RSG) was used to quantify metabolic activity and Propidium Iodide (PI) to evaluate membrane integrity in order to determine the percentage of dormant cells. Cell size and morphology were determined using scanning electronic microscopy. Under carbon starvation at 30°C, Deinococcus sp. UDEC-P1 increased its proportion of dormant cells from 0.1% to 20%, decreased the count of culturable cells and average cell volume decreased 7.1 times. At 4°C, however, the proportion of dormant cells increased only to 6%, without a change in the count of culturable cells and an average cellular volume decrease of 4.1 times and 3% of the dormant cells were able to be awakened. Results indicate a greater proportion of dormant Deinococcus sp. UDEC-P1 cells at 30ºC and it suggests that carbon starvation is more deleterious condition at 30ºC than 4ºC. For this reason Deinococcus sp. UDEC-P1 cells are more likely to enter into dormancy at higher temperature as a strategy to survive. [Int Microbiol 18(3):189-194 (2015)]Keywords: Deinococcus · dormancy · metabolism · starvation · flow cytometr

Internacionalización de la pyme cartagenera : caso Servicios Máximos Ltda., Sicelub Colombia, Progral Medica Ltda

Las micros, pequeñas y medianas empresas (MIPYMES) colombianas 1 , al igual que en la mayoría de los países, son el motor de la economía. Generan más del 50% del empleo nacional, significan el 36% del valor agregado industrial, el 92% de los establecimientos comerciales y el 40% de la producción total del país, lo cual demuestra su importancia y su gran potencial de crecimiento (al comparar su participación en el PIB y el número de establecimientos). Muy a pesar de esto, la expansión exterior de la pequeña y mediana empresa en los últimos años es un dato de especial preocupación en el desarrollo reciente de la economía del país. Esta, se ha caracterizado por la puesta en práctica de estrategias empresariales orientadas fundamentalmente a la exportación, en donde a pesar de las diferentes iniciativas desarrolladas por el gobierno central y las agrupaciones gremiales2 , el aporte de las Pymes a la balanza comercial ha sido muy reducida, a diferencia del notable crecimiento que estas han aportado en los países del sudoeste asiático y europeos como Italia y España por su destacada participación en su comercio exterior. Mientras las exportaciones de las Pymes de Taiwán (US$12.547 millones) corresponden al 56exportaciones totales de la isla, las de Corea (US$18.241 millones) al 40% y las de Italia (US$ 110.552 millones) al 53%, en Colombia, el aporte de las Pymes corresponden a no más del 20% del total de las exportaciones 3 .Incluye bibliografía, anexo

Performance analysis of a hardware accelerator of dependence management for taskbased dataflow programming models

Along with the popularity of multicore and manycore, task-based dataflow programming models obtain great attention for being able to extract high parallelism from applications without exposing the complexity to programmers. One of these pioneers is the OpenMP Superscalar (OmpSs). By implementing dynamic task dependence analysis, dataflow scheduling and out-of-order execution in runtime, OmpSs achieves high performance using coarse and medium granularity tasks. In theory, for the same application, the more parallel tasks can be exposed, the higher possible speedup can be achieved. Yet this factor is limited by task granularity, up to a point where the runtime overhead outweighs the performance increase and slows down the application. To overcome this handicap, Picos was proposed to support task-based dataflow programming models like OmpSs as a fast hardware accelerator for fine-grained task and dependence management, and a simulator was developed to perform design space exploration. This paper presents the very first functional hardware prototype inspired by Picos. An embedded system based on a Zynq 7000 All-Programmable SoC is developed to study its capabilities and possible bottlenecks. Initial scalability and hardware consumption studies of different Picos designs are performed to find the one with the highest performance and lowest hardware cost. A further thorough performance study is employed on both the prototype with the most balanced configuration and the OmpSs software-only alternative. Results show that our OmpSs runtime hardware support significantly outperforms the software-only implementation currently available in the runtime system for finegrained tasks.This work is supported by the Spanish Government through Programa Severo Ochoa (SEV-2015-0493), by the Spanish Ministry of Science and Technology through TIN2015-65316-P project, by the Generalitat de Catalunya (contracts 2014-SGR-1051 and 2014-SGR-1272) and by the European Research Council RoMoL Grant Agreement number 321253. We also thank the Xilinx University Program for its hardware and software donations.Peer ReviewedPostprint (published version

Modelado de procesos y desarrollo de sistemas software: integración entre UML y EPC.

Los objetivos de UML (Unified Modeling Language – Lenguaje Unificado de Modelado) y de la EPC (Event-driven Process Chain - Cadena de Procesos guiada por Eventos), están bien diferenciados: mientras que UML se enfoca al diseño de sistemas de información (SI), las EPCs se emplean para el modelado de procesos de negocios (BPM) dentro de la metodología ARIS. No obstante, es evidente la relación entre ambas técnicas: por una parte, un correcto diseño de SI debe basarse en los requisitos definidos por el modelo de procesos de negocio. Por otra parte, las mejoras de los procesos existentes a menudo deben llevarse a cabo mediante el desarrollo o modificación de los SI que soportan dichos procesos. En esta comunicación se analizan las posibilidades de integración de ambas técnicas de modelad

Mejorar el manejo de lavazas con las que se alimenta a los cerdos de la granja porcicola de la carcel de Palmira

Figuras, tablasEl presente proyecto aplicado, se realiza con el fin de evaluar alternativas de solución al manejo de las lavazas utilizadas en la producción porcícola de la granja de la cárcel de Palmira Valle, las cuales se llevan con procedimientos inadecuados en cuanto a su manejo y suministro a los cerdos, conllevando esto a una alimentación deficiente, con bajos índices nutricionales y problemas sanitarios. El trabajo contempla la evaluación de métodos de manejo basados en el proceso, control, manipulación y suministro de lavazas a los cerdos de la granja porcícola en mención, mejorando los tiempos de producción, conseguir peso adecuado en menor tiempo, disminuir tratamientos correctivos, bajar al mínimo permitido la utilización de desparasitantes, conseguir una ganancia de carne con menor porcentaje de grasa, y por ende lograr mejores utilidades.Management of slop used in hog production farm Valle Palmira prison, which they take withinadequate procedures regarding handling and supply pigs, leading it to a poor diet, lownutritional levels and health problems. The work includes the evaluation of methods of process-based management, control, manipulation and supply slop the pigs of the pig farm in question, improving production times, getting proper weight in less time, reduce corrective treatments, down to minimum allowed use of deworming, make a profit of meat with less fat percentage, and thus achieve better profits

Task dependences management hardware acceleration for task-based dataflow programming models

Task-based programming models have gained a lot of attention for being able to explore high parallelism over multicore and manycore, while hiding the difficulties of parallel programming. For applications with moderate size tasks, performance gains are assured by using these programming models. While for more parallelism by using smaller and more tasks, the performance degrades as a result of runtime overheads. To speed up the runtime, we present a hardware accelerator, Picos Hardware to accelerate task dependence management and scheduling. In this work, we show the performance of the first Picos Hardware prototype realized in a Zynq 7000 All-Programmable SoC by using real benchmarks. Results show that our hardware support greatly outperforms the software-only implementation currentlyavailable in the runtime system for fine-grained tasks

Síndrome Febril Desconocido, Alta Probabilidad de Brucelosis, Reporte de Caso

La brucelosis, causada por la bacteria gram negativa Brucella spp, es una de las grandes imitadoras en el mundo de las enfermedades infecciosas, puede simular diversas enfermedades multisistémicas, exhibir un amplio polimorfismo clínico que frecuentemente lleva a la pérdida de diagnósticos y falla en el tratamiento, aumentando la tasa de complicaciones asociadas a la misma (1). Se considera la más común enfermedad zoonótica de distribución mundial, con más de 500 000 nuevos casos notificados anualmente, con una prevalencia mayor a 1/100000 habitantes en zonas endémicas como el Mediterráneo, la península Arábiga, India, México, Centro y Sur América, en los que la infección es adquirida principalmente a través del contacto directo con animales infectados (1,2).  El reporte de caso muestra un paciente masculino con diagnóstico final de síndrome febril con alta probabilidad de brucelosis, con diagnósticos relacionado de pielonefritis derecha, orquiepididimitis izquierda, epididimitis derecha. Por medio de IgM, IgG y Antígenos febriles se diagnostica Brucella spp, por lo cual se indica manejo antibiótico con Doxiciclina con resolución total del cuadro. Sobresale la importancia de realizar una historia clínica completa en el ingreso del paciente, con énfasis en antecedentes labores

Radial Osteochondroma in a Chilean Pure Breed Rodeo Horse: First Case Reported in this Breed

A 5 year-old Chilean pure breed rodeo gelding was evaluated for lameness in the right forelimb and effusion of the common carpal sheath of the digital flexor tendons. Radiographs revealed exostosis with rounded margins arising from the palmar cortex of the distal metaphysis of the radius. Ultrasonographic examination revealed a thickened and proliferative synovium, excessive anechoic fluid and a hiperechogenic mass protruding from the cortical bone. Tenoscopic exploration confirmed the presence of the mass, and removal was successfully performed through thecotomy. At 4 months postoperatively, the horsed was successfully competing although present mild right forelimb lameness and improving.

A hardware runtime for task-based programming models

© 2019 IEEE. Personal use of this material is permitted. Permission from IEEE must be obtained for all other uses, in any current or future media, including reprinting/republishing this material for advertising or promotional purposes,creating new collective works, for resale or redistribution to servers or lists, or reuse of any copyrighted component of this work in other works.Task-based programming models such as OpenMP 5.0 and OmpSs are simple to use and powerful enough to exploit task parallelism of applications over multicore, manycore and heterogeneous systems. However, their software-only runtimes introduce relevant overhead when targeting fine-grained tasks, resulting in performance losses. To overcome this drawback, we present a hardware runtime Picos++ that accelerates critical runtime functions such as task dependence analysis, nested task support, and heterogeneous task scheduling. As a proof-of-concept, the Picos++ hardware runtime has been integrated with a compiler infrastructure that supports parallel task-based programming models. A FPGA SoC running Linux OS has been used to implement the hardware accelerated part of Picos++, integrated with a heterogeneous system composed of 4 symmetric multiprocessor (SMP) cores and several hardware functional accelerators (HwAccs) for task execution. Results show significant improvements on energy and performance compared to state-of-the-art parallel software-only runtimes. With Picos++, applications can achieve up to 7.6x speedup and save up to 90 percent of energy, when using 4 threads and up to 4 HwAccs, and even reach a speedup of 16x over the software alternative when using 12 HwAccs and small tasks.Peer ReviewedPostprint (author's final draft

Magnetic effect in viscosity of magnetorheological fluids

ABSTRACT: In this work the study of viscosity is presented for a magnetorheological fluid made from iron oxides micrometre, under an external magnetic field. The material was characterized by magnetic loops in a vibrating sample magnetometer and its crystal structure by X-ray diffraction. The results show that saturation magnetization and coercive field have dependence with the powder size. The material has different crystal structure which lattice parameters were determined by Rietveld refinement. The viscosity of the magnetorheological fluid was measured by a viscometer with rotational symmetry with and without external field. This result evidence a dependency on the size, percentage iron oxide and the applied magnetic field, it is due to the hydrodynamic volume of iron oxide interacts with the external magnetic field, increasing the flow resistance