Computational thinking and robotics in education

After the computational thinking sessions in the previous 2016-2018 editions of TEEM Conference, the fourth edition of this track has been organized in the current 2019 edition. Computational thinking is still a very significant topic, especially, but not only, in pre-university education. In this edition, the robotic has a special role in the track, with a strength relationship with the STEM and STEAM education of children at the pre-university levels, seeding the future of our society

Extracellular cysteine in connexins: Role as redox sensors

Indexación: Scopus.Connexin-based channels comprise hemichannels and gap junction channels. The opening of hemichannels allow for the flux of ions and molecules from the extracellular space into the cell and vice versa. Similarly, the opening of gap junction channels permits the diffusional exchange of ions and molecules between the cytoplasm and contacting cells. The controlled opening of hemichannels has been associated with several physiological cellular processes; thereby unregulated hemichannel activity may induce loss of cellular homeostasis and cell death. Hemichannel activity can be regulated through several mechanisms, such as phosphorylation, divalent cations and changes in membrane potential. Additionally, it was recently postulated that redox molecules could modify hemichannels properties in vitro. However, the molecular mechanism by which redox molecules interact with hemichannels is poorly understood. In this work, we discuss the current knowledge on connexin redox regulation and we propose the hypothesis that extracellular cysteines could be important for sensing changes in redox potential. Future studies on this topic will offer new insight into hemichannel function, thereby expanding the understanding of the contribution of hemichannels to disease progression.http://journal.frontiersin.org/article/10.3389/fphys.2016.00001/ful

Blended transdiagnostic group CBT for emotional disorders: A feasibility trial protocol

Introduction: Emotional disorders (anxiety and depressive disorders) are a relevant public health concern associated with high prevalence, high costs, and important disability. Therefore, research priorities include designing and testing cost-effective interventions to reach everyone in need. Internet-delivered interventions for emotional disorders are effective and can help to disseminate and implement evidence-based treatments. However, although these treatments are generally effective, not all patients benefit from this treatment format equally. Blended treatments are a new form of intervention that combines the strengths of face-to-face and Internet approaches. Nevertheless, research on blended interventions has focused primarily on individual therapy, and less attention has been paid to the potential of using this format in group psychotherapy. This study aims to analyze the feasibility of blended transdiagnostic group CBT for emotional disorders. The current article describes the study protocol for this trial. Method and analysis: A one-armed pilot trial will be conducted. Participants will be 30 adults suffering from DSM-5 anxiety and/or depressive disorders. The treatment consists of a blended transdiagnostic group intervention delivered during a period of 24 weeks. Groups of 6 to 10 patients will attend a total of eight 2-hour, face-to-face sessions, alternated with the use of an online platform where they will find the contents of the treatment protocol. The intervention has four core components: present-focused awareness, cognitive flexibility, identification and modification of behavioral and cognitive patterns of emotional avoidance, and interoceptive and situational exposure. These components are delivered in 16 modules. Assessments will be performed at baseline, during the treatment, at post-treatment, and at 3-month follow-up. Clinical and treatment acceptability outcomes will be included. Quantitative and qualitative data (participants’ views about blended group psychotherapy) will be analyzed. Ethics and dissemination: The trial has received ethical approval from the Ethics Committee of Universitat Jaume I (September 2019) and will be conducted in accordance with the study protocol, the Declaration of Helsinki, and good clinical practice. The results of this study will be disseminated by presentation at conferences and will be submitted for publication in a peer-reviewed journal. Trial registration: ClinicalTrials.gov Identifier: NCT04008576. Registered 05 July 2019, https://clinicaltrials.gov/ct2/show/NCT0400857

S wave velocity structure below central Mexico using high-resolution surface wave tomography

Shear wave velocity of the crust below central Mexico is estimated using surface wave dispersion measurements from regional earthquakes recorded on a dense, 500 km long linear seismic network. Vertical components of regional records from 90 well-located earthquakes were used to compute Rayleigh-wave group-velocity dispersion curves. A tomographic inversion, with high resolution in a zone close to the array, obtained for periods between 5 and 50 s reveals significant differences relative to a reference model, especially at larger periods (>30 s). A 2-D S wave velocity model is obtained from the inversion of local dispersion curves that were reconstructed from the tomographic solutions. The results show large differences, especially in the lower crust, among back-arc, volcanic arc, and fore-arc regions; they also show a well-resolved low-velocity zone just below the active part of the Trans Mexican Volcanic Belt (TMVB) suggesting the presence of a mantle wedge. Low densities in the back arc, inferred from the low shear wave velocities, can provide isostatic support for the TMVB

An infinite family of magnetized Morgan-Morgan relativistic thin disks

Applying the Horsk\'y-Mitskievitch conjecture to the empty space solutions of Morgan and Morgan due to the gravitational field of a finite disk, we have obtained the corresponding solutions of the Einstein-Maxwell equations. The resulting expressions are simply written in terms of oblate spheroidal coordinates and the solutions represent fields due to magnetized static thin disk of finite extension. Now, although the solutions are not asymptotically flat, the masses of the disks are finite and the energy-momentum tensor agrees with the energy conditions. Furthermore, the magnetic field and the circular velocity show an acceptable physical behavior.Comment: Submitted to IJTP. This paper is a revised and extended version of a paper that was presented at arXiv:1006.203