Nanoestructuras magnéticas multifuncionales para aplicaciones biomédicas

Recientemente, la nanomedicina ha surgido de la interfaz entre la nanotecnología y la biotecnología, dando lugar a la aparición de importantes avances en el sector biomédico. Esta nueva vertiente de la biomedicina, requiere el desarrollo de materiales que incorporen nanoestructuras multifuncionales que integren en una única estructura materiales con propiedades específicas con actividad teragnóstica, como son las nanopartículas magnéticas, para diversas aplicaciones biomédicas in vitro o in vivo. En el presente trabajo, se ha llevado a cabo la síntesis de nanoestructuras magnéticas por diferentes rutas sintéticas optimizadas y su posterior evaluación en aplicaciones biomédicas de actual interés tales como la detección de biomarcadores de enfermedades neurodegenerativas, terapias celulares o el diagnóstico por imagen multimodal

Standardization Framework for Sustainability from Circular Economy 4.0

The circular economy (CE) is widely known as a way to implement and achieve sustainability, mainly due to its contribution towards the separation of biological and technical nutrients under cyclic industrial metabolism. The incorporation of the principles of the CE in the links of the value chain of the various sectors of the economy strives to ensure circularity, safety, and efficiency. The framework proposed is aligned with the goals of the 2030 Agenda for Sustainable Development regarding the orientation towards the mitigation and regeneration of the metabolic rift by considering a double perspective. Firstly, it strives to conceptualize the CE as a paradigm of sustainability. Its principles are established, and its techniques and tools are organized into two frameworks oriented towards causes (cradle to cradle) and effects (life cycle assessment), and these are structured under the three pillars of sustainability, for their projection within the proposed framework. Secondly, a framework is established to facilitate the implementation of the CE with the use of standards, which constitute the requirements, tools, and indicators to control each life cycle phase, and of key enabling technologies (KETs) that add circular value 4.0 to the socio-ecological transition

Perfectionism Profiles and Anger Responses: The Relevant Role of Self-Esteem in Athletes of Professional Quarries

Perfectionism is a multidimensional personality trait characterized by effort and rigidity in setting high personal standards, accompanied by an excessive tendency toward critical assessments, which plays an important role in cognitive, behavioral, and emotional functioning. During adolescence, personality is built on a fundamental pillar—self-esteem—which plays an important role in sports practice when it comes to achieving the best possible performance. Anger has an emotional component that, interpreted in an unadaptive way, interferes with sports performance. The aim of this study is to assess differences according to self-esteem and perfectionism indicators and anger expression and management in young athletes. The sample included 229 male athletes to the quarries of professional sports with ages between 13 and 17 years. They were administered the Multidimensional Perfectionism Scale, the State-Trait Anger Expression Inventory for Children and Adolescents, the Rosenberg Self-esteem Scale, and a socio-demographic questionnaire. Predictive analysis showed that low personal standards and high levels of organization (indicators of adaptive perfectionism) acted as predictors of state anger, while those showing high personal standards predicted high anger management in athletes with high self-esteem. High personal standards predicted lower indicators of trait anger in athletes with low self-esteem. The results revealed the influence of high self-esteem as a protective factor in the predictive relationship among anger traits and personal standards. The study describes the relationship of these variables in the belongings of young male footballers (under high sport pressure), showing the need to take care of the athletes’ self-esteem in sport environments through prevention programs that include psychological and social resources training systems

Analysis of uncertainty in a middle-cost device for 3D measurements in BIM perspective

Medium-cost devices equipped with sensors are being developed to get 3D measurements. Some allow for generating geometric models and point clouds. Nevertheless, the accuracy of these measurements should be evaluated, taking into account the requirements of the Building Information Model (BIM). This paper analyzes the uncertainty in outdoor/indoor three-dimensional coordinate measures and point clouds (using Spherical Accuracy Standard (SAS) methods) for Eyes Map, a medium-cost tablet manufactured by e-Capture Research & Development Company, Mérida, Spain. To achieve it, in outdoor tests, by means of this device, the coordinates of targets were measured from 1 to 6 m and cloud points were obtained. Subsequently, these were compared to the coordinates of the same targets measured by a Total Station. The Euclidean average distance error was 0.005–0.027 m for measurements by Photogrammetry and 0.013–0.021 m for the point clouds. All of them satisfy the tolerance for point cloud acquisition (0.051 m) according to the BIM Guide for 3D Imaging (General Services Administration); similar results are obtained in the indoor tests, with values of 0.022 m. In this paper, we establish the optimal distances for the observations in both, Photogrammetry and 3D Photomodeling modes (outdoor) and point out some working conditions to avoid in indoor environments. Finally, the authors discuss some recommendations for improving the performance and working methods of the device.peerReviewe

ITERL: A Wireless Adaptive System for Efficient Road Lighting

This work presents the development and construction of an adaptive street lighting system that improves safety at intersections, which is the result of applying low-power Internet of Things (IoT) techniques to intelligent transportation systems. A set of wireless sensor nodes using the Institute of Electrical and Electronics Engineers (IEEE) 802.15.4 standard with additional internet protocol (IP) connectivity measures both ambient conditions and vehicle transit. These measurements are sent to a coordinator node that collects and passes them to a local controller, which then makes decisions leading to the streetlight being turned on and its illumination level controlled. Streetlights are autonomous, powered by photovoltaic energy, and wirelessly connected, achieving a high degree of energy efficiency. Relevant data are also sent to the highway conservation center, allowing it to maintain up-to-date information for the system, enabling preventive maintenance.Consejería de Fomento y Vivienda Junta de Andalucía G-GI3002 / IDIOFondo Europeo de Desarrollo Regional G-GI3002 / IDI

Emotions Detection based on a Single-electrode EEG Device

The study of emotions using multiple channels of EEG represents a widespread practice in the field of research related to brain computer interfaces (Brain Computer Interfaces). To date, few studies have been reported in the literature with a reduced number of channels, which when used in the detection of emotions present results that are less accurate than the rest. To detect emotions using an EEG channel and the data obtained is useful for classifying emotions with an accuracy comparable to studies in which there is a high number of channels, is of particular interest in this research framework. This article uses the Neurosky Maindwave device; which has a single electrode to acquire the EEG signal, Matlab software and IBM SPSS Modeler; which process and classify the signals respectively. The accuracy obtained in the detection of emotions in relation to the economic resources of the hardware dedicated to the acquisition of EEG signal is remarkable

Indoor Position System based on BitCloud Stack for Ambient Living and Smart Buildings

Nowadays there is a research on ambient living and smart building applications to make people life more confortable. This kind of applications, in general, requires the position where a person is in a building to act according it and to any physical parameters that are measured from the person, to determine, for instance, if the air condition has to be switched on or off, the room temperature has to be put up or down or the music has to be changed from classical to pop, or vice versa. This paper presents an indoor position solution based on BitCloud Stack, a full-featured, second generation embedded software stack from Atmel.Junta de Andalucía p08-TIC-363

Modelo dinámico para la gestión integrada de proyectos de construcción

Los avances que se vienen desarrollando en las tecnologías de la información han sido rápidamente aprovechados e integrados en las grandes corporaciones productivas en los diferentes ámbitos de actuación. Sin embargo, por sus particularidades, la explotación de las posibilidades que ofrecen las nuevas tecnologías en la industria de la construcción presenta dificultades. Se propone el análisis de la implantación de un modelo de dirección de proyectos en el ámbito de la construcción (PMBOK), en un entorno colaborativo entre empresas, socios y stakeholders, considerando especialmente la perspectiva informacional y el impacto en la satisfacción del cliente, usando como indicadores la información generada desde el área de calidad, evaluando las oportunidades que ofrece la gestión integrada mediante nuevas tecnologías de la información. Primeramente se describen los elementos fundamentales del modelo propuesto, identificando los flujos de información, según el estándar que propone la guía del PMBOK. A continuación se muestra la tecnología de implementación desde la perspectiva informacional para la calidad, soportada mediante una plataforma de agentes inteligentes distribuidos. Finalmente se detallan los resultados obtenidos mediante simulación con Dinámica de Sistemas en los casos de aplicación del modelo de gestión integrada de proyectos usando nuevas tecnologías de información distribuida y sin ellas, respectivamente.The advances are been developing about information technologies have been improved and integrated by big productive corporations in the different ways of work so quickly. However the possibilities of the operation that new technologies in construction industry offer give some difficulties due to its peculiarities. A model of introduction analysis project management in construction field is proposed at companies, partnership and stakeholders collaborative environments, with the consideration of the informational view and the impact in customer satisfaction, being used as indicators the generated information from the quality area, to assess the opportunities that offers the integrated management through new information technologies. Firstly the fundamental parts of the proposed model are described, being identified the information flows, according to the standard that PMBOK guide proposes. Next, the implementation technology is shown from the information perspective view for the quality, being supported by distributed intelligent agents platform. Finally, the achievement results through the simulation with Dynamic Systems in the different ways of application of the integrated project management model is detailed, being used new distributed information technologies or without them

Redox-dependent and redox-independent functions of Caenorhabditis elegans thioredoxin 1

Thioredoxins (TRX) are traditionally considered as enzymes catalyzing redox reactions. However, redox-independent functions of thioredoxins have been described in different organisms, although the underlying molecular mechanisms are yet unknown. We report here the characterization of the first generated endogenous redox-inactive thioredoxin in an animal model, the TRX-1 in the nematode Caenorhabditis elegans. We find that TRX-1 dually regulates the formation of an endurance larval stage (dauer) by interacting with the insulin pathway in a redox-independent manner and the cGMP pathway in a redox-dependent manner. Moreover, the requirement of TRX-1 for the extended longevity of worms with compromised insulin signalling or under calorie restriction relies on TRX-1 redox activity. In contrast, the nuclear translocation of the SKN-1 transcription factor and increased LIPS-6 protein levels in the intestine upon trx-1 deficiency are strictly redox-independent. Finally, we identify a novel function of C. elegans TRX-1 in male food-leaving behaviour that is redox-dependent. Taken together, our results position C. elegans as an ideal model to gain mechanistic insight into the redox-independent functions of metazoan thioredoxins, overcoming the limitations imposed by the embryonic lethal phenotypes of thioredoxin mutants in higher organisms.NIH Office of Research Infrastructure P40 OD010440Spanish Ministry of Economy and Competitiveness BFU2015- 64408-PFondo Social Europeo BFU2015- 64408-PNational Institute of Allergy and Infectious Diseases of the National Institutes of Health R01AI07640