Guías Argentinas para el diagnóstico, la prevención y el tratamiento de la osteoporosis 2015

La osteoporosis es una enfermedad en constante crecimiento y que afecta a más de 200 millones de personas en todo el mundo. Nuestras recomendaciones son guías para el diagnóstico, la prevención y tratamiento, pero no normas para las decisiones clínicas en casos individuales. El médico debe adaptarlas a situaciones en la práctica clínica cotidiana, incorporando factores personales que trascienden los límites de estas guías y hacen al saber y al arte de la práctica médica. Como todo conocimiento científico, deben ser actualizadas periódicamente a medida que se adquieran nuevas, mejores y más efectivas herramientas diagnósticas y terapéuticas.Osteoporosis is an evolving disease which affects over 200 million people worldwide. Our recommendations are guidelines for its diagnosis, prevention and treatment, but they do not constitute standards for clinical decisions in individual cases. The physician must adapt them to individual special situations, incorporating personal factors that transcend the limits of these guidelines and are dependent on the knowledge and art of the practice of Medicine. These guidelines should be reviewed and updated periodically as new, better and more effective diagnostic and therapeutic tools become available

Averaging Generalized Scalar Field Cosmologies II: Locally Rotationally Symmetric Bianchi I and flat Friedmann-Lema\^itre-Robertson-Walker models

Scalar field cosmologies with a generalized harmonic potential and a matter fluid with a barotropic Equation of State (EoS) with barotropic index $\gamma$ for the Locally Rotationally Symmetric (LRS) Bianchi I and flat Friedmann-Lema\^itre-Robertson-Walker (FLRW) metrics are investigated. Methods from the theory of averaging of nonlinear dynamical systems are used to prove that time-dependent systems and their corresponding time-averaged versions have the same late-time dynamics. Therefore, the simplest time-averaged system determines the future asymptotic behavior. Depending on the values of $\gamma$, the late-time attractors of physical interests are flat quintessence dominated FLRW universe and Einstein-de Sitter solution. With this approach, the oscillations entering the system through the Klein-Gordon (KG) equation can be controlled and smoothed out as the Hubble parameter $H$ - acting as time-dependent perturbation parameter - tends monotonically to zero. Numerical simulations are presented as evidence of such behavior.Comment: Research Program Averaging Generalized Scalar Field Cosmologies, part II. 27 pages, 7 compound figures. Minor revision. References updated. Discussion improve

Averaging Generalized Scalar Field Cosmologies I: Locally Rotationally Symmetric Bianchi III and open Friedmann-Lema\^itre-Robertson-Walker models

Scalar field cosmologies with a generalized harmonic potential and a matter fluid with a barotropic Equation of State (EoS) with barotropic index $\gamma$ for Locally Rotationally Symmetric (LRS) Bianchi III metric and open Friedmann-Lema\^itre-Robertson-Walker (FLRW) metric are investigated. Methods from the theory of averaging of nonlinear dynamical systems are used to prove that time-dependent systems and their corresponding time-averaged versions have the same late-time dynamics. Therefore, simple time-averaged systems determine the future asymptotic behavior. Depending on values of barotropic index $\gamma$ late-time attractors of physical interests for LRS Bianchi III metric are Bianchi III flat spacetime, matter dominated FLRW universe (mimicking de Sitter, quintessence or zero acceleration solutions) and matter-curvature scaling solution. For open FLRW metric late-time attractors are a matter dominated FLRW universe and Milne solution. With this approach, oscillations entering nonlinear system through Klein-Gordon (KG) equation can be controlled and smoothed out as the Hubble factor $H$ - acting as a time-dependent perturbation parameter - tends monotonically to zero. Numerical simulations are presented as evidence of such behaviour.Comment: Research Program Averaging Generalized Scalar Field Cosmologies, part I. 48 pages, 24 compound figures. Minor revision. References adde

Educational interventions to improve maternal‐foetal outcomes in women with gestational diabetes

To evaluate improvement in gestational diabetes (GDM) outcomes for mothers and their offspring induced by education provided to the healthcare team (HCTM) and women with GDM, plus coordination between primary care units (PCU) and highly complex maternity (HCM) facilities.Fil: Gorbán de Lapertosa, Silvia. Universidad Nacional del Nordeste; ArgentinaFil: Elgart, Jorge Federico. Consejo Nacional de Investigaciones Científicas y Técnicas. Centro Científico Tecnológico Conicet - La Plata. Centro de Endocrinología Experimental y Aplicada. Universidad Nacional de La Plata. Facultad de Ciencias Médicas. Centro de Endocrinología Experimental y Aplicada; ArgentinaFil: González, Claudio D.. Centro de Educación Médica e Investigaciones Clínicas "Norberto Quirno"; ArgentinaFil: Alvariñas, Jorge. Gobierno de la Ciudad Autónoma de Buenos Aires. Hospital General de Agudos Enrique Tornú; ArgentinaFil: Camin, Paula. Gobierno de la Ciudad Autonoma de Buenos Aires. Hospital General de Agudos Doctor Cosme Argerich.; ArgentinaFil: Mezzabotta, Leonardo. Gobierno de la Ciudad Autonoma de Buenos Aires. Hospital General de Agudos Doctor Cosme Argerich.; ArgentinaFil: Salzberg, Susana. Instituto Centenario, Department Of Medical Research; Argentina. Instituto Centenario, Salud y Calidad de Vida; ArgentinaFil: Gagliardino, Juan Jose. Consejo Nacional de Investigaciones Científicas y Técnicas. Centro Científico Tecnológico Conicet - La Plata. Centro de Endocrinología Experimental y Aplicada. Universidad Nacional de La Plata. Facultad de Ciencias Médicas. Centro de Endocrinología Experimental y Aplicada; Argentin

Cost-effectiveness of a hypertension management programme in an elderly population: a Markov model

<p>Abstract</p> <p>Background</p> <p>Mounting evidence shows that multi-intervention programmes for hypertension treatment are more effective than an isolated pharmacological strategy. Full economic evaluations of hypertension management programmes are scarce and contain methodological limitations. The aim of the study was to evaluate if a hypertension management programme for elderly patients is cost-effective compared to usual care from the perspective of a third-party payer.</p> <p>Methods</p> <p>We built a cost-effectiveness model using published evidence of effectiveness of a comprehensive hypertension programme vs. usual care for patients 65 years or older at a community hospital in Buenos Aires, Argentina. We explored incremental cost-effectiveness between groups. The model used a life-time framework adopting a third-party payer's perspective. Incremental cost-effectiveness ratio (ICER) was calculated in International Dollars per life-year gained. We performed a probabilistic sensitivity analysis (PSA) to explore variable uncertainty.</p> <p>Results</p> <p>The ICER for the base-case of the "Hypertension Programme" versus the "Usual care" approach was 1,124 International Dollars per life-year gained. PSA did not significantly influence results. The programme had a probability of 43% of being dominant (more effective and less costly) and, overall, 95% chance of being cost-effective.</p> <p>Discussion</p> <p>Results showed that "Hypertension Programme" had high probabilities of being cost-effective under a wide range of scenarios. This is the first sound cost-effectiveness study to assess a comprehensive hypertension programme versus usual care. This study measures hard outcomes and explores robustness through a probabilistic sensitivity analysis.</p> <p>Conclusions</p> <p>The comprehensive hypertension programme had high probabilities of being cost-effective versus usual care. This study supports the idea that similar programmes could be the preferred strategy in countries and within health care systems where hypertension treatment for elderly patients is a standard practice.</p

Argentine guidelines for the diagnosis, prevention and treatment of osteoporosis, 2015

La osteoporosis es una enfermedad en constante crecimiento y que afecta a más de 200 millones de personas en todo el mundo. Nuestras recomendaciones son guías para el diagnóstico, la prevención y tratamiento, pero no normas para las decisiones clínicas en casos individuales. El médico debe adaptarlas a situaciones en la práctica clínica cotidiana, incorporando factores personales que trascienden los límites de estas guías y hacen al saber y al arte de la práctica médica. Como todo conocimiento científico, deben ser actualizadas periódicamente a medida que se adquieran nuevas, mejores y más efectivas herramientas diagnósticas y terapéuticas.Osteoporosis is an evolving disease which affects over 200 million people worldwide. Our recommendations are guidelines for its diagnosis, prevention and treatment, but they do not constitute standards for clinical decisions in individual cases. The physician must adapt them to individual special situations, incorporating personal factors that transcend the limits of these guidelines and are dependent on the knowledge and art of the practice of Medicine. These guidelines should be reviewed and updated periodically as new, better and more effective diagnostic and therapeutic tools become available.Laboratorio de Investigación en Osteopatías y Metabolismo Minera

Correlation energy and spin polarization in the 2D electron gas

The ground state energy of the two--dimensional uniform electron gas has been calculated with fixed--node diffusion Monte Carlo, including backflow correlations, for a wide range of electron densities as a function of spin polarization. We give a simple analytic representation of the correlation energy which fits the density and polarization dependence of the simulation data and includes several known high- and low-density limits. This parametrization provides a reliable local spin density energy functional for two-dimensional systems and an estimate for the spin susceptibility. Within the proposed model for the correlation energy, a weakly first--order polarization transition occurs shortly before Wigner crystallization as the density is lowered.Comment: Minor typos corrected, see erratum: Phys. Rev. Lett. 91, 109902(E) (2003

Prevalencia de anemia en Estudiantes de la Facultad de Ciencias Químicas de la UANL

Objetivo: La anemia es una entidad clínica que, al estar vinculada a sensaciones de cansancio y debilidad, puede dificultar el desempeño académico. El objetivo del trabajo fue determinar la prevalencia de anemia en estudiantes universitarios y su relación con el IMC. Métodos: Se diseñó una investigación de tipo observacional de corte transversal, constituida por 187 estudiantes de la FCQ, UANL en el periodo Enero-Junio 2017. La toma de muestras sanguíneas se realizó por punción venosa utilizando el sistema de extracción al vacío con EDTA como anticoagulante y se determinó la hemoglobina, recuento de hematíes e índices eritrocitarios. Resultados: El promedio de edad de los estudiantes evaluados fue de 18.59 ±1.21. Se observó que el 3.7% de la población resulto con un estado de anemia, 4 casos con anemia normocítica normocrómica (57%), 2 casos con anemia normocitica hipocrómica (29%) y un caso de anemia microcitica normocrómica (14%); el 1.08% de los hombres presento anemia mientras que el 6.31% de las mujeres la padece. Con relación al IMC, se determinó el porcentaje de estudiantes con bajo peso, peso normal, sobrepeso y obesidad, siendo estos de 20.81, 44.96, 17.45 y 16.78% respectivamente. No se encontró asociación estadísticamente significativa entre el IMC y la anemia (p= 0.41). Conclusiones: La prevalencia de anemia en estudiantes de la facultad de Ciencias Químicas de la UANL es de 3.7%

Guidelines for the diagnosis, prevention and treatment of osteoporosis, 2012

La osteoporosis es una patología en constante crecimiento y que afecta a más de 200 millones de personas a nivel mundial. Las recomendaciones presentes son guías para el diagnóstico, la prevención y tratamiento pero no normas para las decisiones clínicas en pacientes individuales. El médico debe adaptarlas a situaciones y pacientes deferentes, incorporando factores personales que trascienden los límites de estas guías y hacen al saber y al arte del médico. Como todo conocimiento médico científico deben ser revisadas y actualizadas periódicamente a medida que se adquieran nuevas, mejores y más efectivas herramientas diagnósticas y terapéuticas.Osteoporosis is a constantly growing disease which affects over 200 million people worldwide. The present recommendations are guidelines for its diagnosis, prevention and treatment, but they do not constitute standards for clinical decisions in individual patients. The physician must adapt them to individual patients and special situations, incorporating personal factors that transcend the limits of these guidelines and are dependent on the knowledge and art of the physician. These guidelines should be reviewed and updated periodically as new, better and more effective diagnostic and therapeutic tools become available.Fil: Schurman, Leon. Grupo de Investigación en Osteopatías y Metabolismo Mineral; ArgentinaFil: Bagur, Alicia. Centro de Osteopatías Médicas; ArgentinaFil: Claus Hermberg, Heraldo. Hospital Alemán; ArgentinaFil: Messina, Osvaldo D.. Ministerio de Defensa. Ejercito Argentino. Hospital Militar Central Cirujano Mayor "Cosme Argerich"; ArgentinaFil: Negri, Armando L.. Universidad del Salvador; ArgentinaFil: Sánchez, Ariel. Centro de Endocrinología; ArgentinaFil: González, Claudio. Centro de Educación Médica e Investigaciones Clínicas; ArgentinaFil: Diehl, María. Hospital Italiano de Buenos Aires; ArgentinaFil: Rey, Paula. Universidad del Salvador; ArgentinaFil: Gamba, Julieta. Ministerio de Defensa. Ejercito Argentino. Hospital Militar Central Cirujano Mayor "Cosme Argerich"; ArgentinaFil: Chiarpenello, Javier. Universidad Nacional de Rosario; ArgentinaFil: Moggia, María Susana. Universidad de Buenos Aires. Facultad de Medicina. Hospital de Clínicas General San Martín; ArgentinaFil: Mastaglia, Silvina Rosana. Consejo Nacional de Investigaciones Científicas y Técnicas. Oficina de Coordinación Administrativa Houssay. Instituto de Inmunología, Genética y Metabolismo; Argentin

Morphosedimentary characterization of sublittoral beds of San Andres beach (Malaga Bay) using side scan sonar

The present work contributes to the characterization and mapping of sublittoral seabed located in the nearshore of the San Andrés Beach in Malaga. This zone extends between the outer dock of the Malaga harbor and the Guadalhorce river mouth. The study was done using the description of the acoustic reflection patterns obtained with Side Scan Sonar thechniques. These patterns have been identified with lithological changes, morphological features, dimension and orientation of bedforms, underwater patrimony and evidences of the human activity on the seabe