A taxonomical framework of socio-cultural hazards in transport hubs

This article presents a taxonomical framework that supports the considerations of socio-cultural hazards that may affect crowd management in transport hubs, i.e. airports, ports, underground and train stations, both in normal and emergency situations. Such hazards include communication breakdowns with passengers due, for instance, to language barriers; increased potential for revolts, as in stranded passenger situations; misreporting of security threats; and uncooperative behaviour in case of emergencies. Such socio-cultural hazards are not normally considered from the integrated perspective of transport hub operators, e.g. security staff, first responders and service assistants as well as safety and security managers. The present study provides an integrated perspective of these hazards as a means to increase the performance of transport staff members that interact with the public and with passengers on a daily basis. The methodology used to develop the framework comprises: (i) a focus group with relevant experts, (ii) semi-structured interviews at operational facilities with front-end practitioners, and (iii) a review of academic literature and media reports. The framework has also been qualitatively corroborated with transport operators in dedicated interviews and a focus group session. The study identified 10 socio-cultural hazards that were combined into a single framework comprising three high-level sub-categories: (i) crowd–staff interactions, (ii) crowd–crowd interactions, and (iii) crowd–environment interactions. The framework of socio-cultural factors can increase staff’s awareness of relevant socio-cultural hazards, their potential consequences in both normal and emergency situations, and the associated mitigation strategies. In turn, this can increase the quality and continuity of service, safety and security in the management of members of the public and passengers in transport hubs

Heart Rate Variability In Athletes And Nonathletes At Rest And During Head-up Tilt.

The purpose of the present study was to determine if autonomic heart rate modulation, indicated by heart rate variability (HRV), differs during supine rest and head-up tilt (HUT) when sedentary and endurance-trained cyclists are compared. Eleven sedentary young men (S) and 10 trained cyclists (C) were studied. The volunteers were submitted to a dynamic ECG Holter to calculate HRV at rest and during a 70 masculine HUT. The major aerobic capacity of athletes was expressed by higher values of VO2 at anaerobic threshold and peak conditions (P < 0.05). At rest the athletes had lower heart rates (P < 0.05) and higher values in the time domain of HRV compared with controls (SD of normal RR interval, SDNN, medians): 59.1 ms (S) vs 89.9 ms (C), P < 0.05. During tilt athletes also had higher values in the time domain of HRV compared with controls (SDNN, medians): 55.7 ms (S) vs 69.7 ms (C), P < 0.05. No differences in power spectral components of HRV at rest or during HUT were detected between groups. Based on the analysis of data by the frequency domain method, we conclude that in athletes the resting bradycardia seems to be much more related to changes in intrinsic mechanisms than to modifications in autonomic control. Also, HUT caused comparable changes in sympathetic and parasympathetic modulation of the sinus node in both groups.38639-4

Catálogo Taxonômico da Fauna do Brasil: setting the baseline knowledge on the animal diversity in Brazil

The limited temporal completeness and taxonomic accuracy of species lists, made available in a traditional manner in scientific publications, has always represented a problem. These lists are invariably limited to a few taxonomic groups and do not represent up-to-date knowledge of all species and classifications. In this context, the Brazilian megadiverse fauna is no exception, and the Catálogo Taxonômico da Fauna do Brasil (CTFB) (http://fauna.jbrj.gov.br/), made public in 2015, represents a database on biodiversity anchored on a list of valid and expertly recognized scientific names of animals in Brazil. The CTFB is updated in near real time by a team of more than 800 specialists. By January 1, 2024, the CTFB compiled 133,691 nominal species, with 125,138 that were considered valid. Most of the valid species were arthropods (82.3%, with more than 102,000 species) and chordates (7.69%, with over 11,000 species). These taxa were followed by a cluster composed of Mollusca (3,567 species), Platyhelminthes (2,292 species), Annelida (1,833 species), and Nematoda (1,447 species). All remaining groups had less than 1,000 species reported in Brazil, with Cnidaria (831 species), Porifera (628 species), Rotifera (606 species), and Bryozoa (520 species) representing those with more than 500 species. Analysis of the CTFB database can facilitate and direct efforts towards the discovery of new species in Brazil, but it is also fundamental in providing the best available list of valid nominal species to users, including those in science, health, conservation efforts, and any initiative involving animals. The importance of the CTFB is evidenced by the elevated number of citations in the scientific literature in diverse areas of biology, law, anthropology, education, forensic science, and veterinary science, among others

Baroreceptor reflex and integrative stress responses in chronic fatigue syndrome

Objective: Altered cardiovascular responses to mental and postural stressors have been reported in chronic fatigue syndrome (CFS). This study examined whether those findings may involve changes in baroreceptor reflex functioning. Methods: Chronotropic baroreceptor reflex (by sequential analysis) and cardiovascular stress responses were recorded during postural (5-minute of active standing) and cognitive (speech task) stress testing in patients with CFS grouped into cases with severe (N = 21) or less severe (N = 22) illness, and in 29 matched control subjects. Results: Patients with CFS had a greater decline in baroreceptor reflex sensitivity (BRS) during standing, although only those with severe CFS were significantly different from the controls. Systolic blood pressure declined during standing in the control group but was maintained in the CFS patients. In contrast, the patients with less severe CFS had blunted increases in blood pressure during the speech task, which could not, however, be explained by inadequate inhibition of the baroreceptor reflex, with all groups showing an appropriate reduction in BRS during the task. Conclusions: These results indicate that in CFS, deficiencies in orthostatic regulation, but not in centrally mediated stress responses, may involve the baroreceptor reflex. This study also suggests that classifying patients with CFS on illness severity may discriminate between patients with abnormalities in peripheral vs. central mechanisms of cardiovascular stress responses.65588989

La pasta Fresca, ripiena e gli gnocchi nella cucina della tradizione regionale.

La pasta fresca, ripiena e gli gnocchi rappresentano un'eccelleza della cucina regionale italiana. La storia, e la tecnica di produzione di fettuccine, lasagne, trofie, bigoli, maltagliati, pici, cavatelli, orecchiette,gnocchi di patate, zucca e semolino, tanto per citare alcuni esempi, costituiscono un grande patrimonio della nostra gastronomi

Acetaminophen inhibits hemoprotein-catalyzed lipid peroxidation and attenuates rhabdomyolysis-induced renal failure

Hemoproteins, hemoglobin and myoglobin, once released from cells can cause severe oxidative damage as a consequence of heme redox cycling between ferric and ferryl states that generates radical species that induce lipid peroxidation. We demonstrate in vitro that acetaminophen inhibits hemoprotein-induced lipid peroxidation by reducing ferryl heme to its ferric state and quenching globin radicals. Severe muscle injury (rhabdomyolysis) is accompanied by the release of myoglobin that becomes deposited in the kidney, causing renal injury. We previously showed in a rat model of rhabdomyolysis that redox cycling between ferric and ferryl myoglobin yields radical species that cause severe oxidative damage to the kidney. In this model, acetaminophen at therapeutic plasma concentrations significantly decreased oxidant injury in the kidney, improved renal function, and reduced renal damage. These findings also provide a hypothesis for potential therapeutic applications for acetaminophen in diseases involving hemoprotein-mediated oxidative injury