3 research outputs found

    Assessing Sustainable Value Creation in Social Enterprises

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    This research explored how ten social enterprises (SEs) in the Philippines create environmental, economic, and social value in the short and long term. This analysis of sustainable value creation (SVC) was the basis for the development of an assessment tool using the sustainable value framework of Hart and Milstein (2003). The resulting assessment tool, referred to as the SVC-SE Assessment Tool, allows SEs to do a rapid assessment on how they generate environmental, economic, and social effectiveness, efficiency and resilience. A portfolio balance indicates if the SE is creating sustainable value and the resulting scores per aspect and quadrant can help the SE get a sense of performance in the different aspects of SVC. The tool that can give a quick overview of the current SVC of the SE and can also provide assistance in planning for future activities

    8th IAS Conference on HIV Pathogenesis, Treatment and Prevention (IAS 2015).

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    The impact of surgical delay on resectability of colorectal cancer: An international prospective cohort study

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    AimThe SARS-CoV-2 pandemic has provided a unique opportunity to explore the impact of surgical delays on cancer resectability. This study aimed to compare resectability for colorectal cancer patients undergoing delayed versus non-delayed surgery.MethodsThis was an international prospective cohort study of consecutive colorectal cancer patients with a decision for curative surgery (January-April 2020). Surgical delay was defined as an operation taking place more than 4 weeks after treatment decision, in a patient who did not receive neoadjuvant therapy. A subgroup analysis explored the effects of delay in elective patients only. The impact of longer delays was explored in a sensitivity analysis. The primary outcome was complete resection, defined as curative resection with an R0 margin.ResultsOverall, 5453 patients from 304 hospitals in 47 countries were included, of whom 6.6% (358/5453) did not receive their planned operation. Of the 4304 operated patients without neoadjuvant therapy, 40.5% (1744/4304) were delayed beyond 4 weeks. Delayed patients were more likely to be older, men, more comorbid, have higher body mass index and have rectal cancer and early stage disease. Delayed patients had higher unadjusted rates of complete resection (93.7% vs. 91.9%, P = 0.032) and lower rates of emergency surgery (4.5% vs. 22.5%, P ConclusionOne in 15 colorectal cancer patients did not receive their planned operation during the first wave of COVID-19. Surgical delay did not appear to compromise resectability, raising the hypothesis that any reduction in long-term survival attributable to delays is likely to be due to micro-metastatic disease
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