5,474 research outputs found

    Evaluation of methods of reducing community noise impact around San Jose municipal airport

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    A computer simulation of the airport noise impact on the surrounding communities was used to evaluate alternate operational procedures, improved technology, and land use conversion as methods of reducing community noise impact in the airport vicinity. In addition, a constant density population distribution was analyzed for possible application to other airport communities with fairly uniform population densities and similar aircraft operational patterns. The introduction of sound absorption material (SAM) was found to reduce community noise annoyance by over 25 percent, and the introduction of refan was found to reduce community annoyance by over 60 percent. Replacing the present aircraft was found to reduce the noise problem to very small proportions, and the introduction of an advanced technology twin was found to essentially eliminate the community noise problem

    The Mechanisms of Vesicle Budding and Fusion

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    AbstractGenetic and biochemical analyses of the secretory pathway have produced a detailed picture of the molecular mechanisms involved in selective cargo transport between organelles. This transport occurs by means of vesicular intermediates that bud from a donor compartment and fuse with an acceptor compartment. Vesicle budding and cargo selection are mediated by protein coats, while vesicle targeting and fusion depend on a machinery that includes the SNARE proteins. Precise regulation of these two aspects of vesicular transport ensures efficient cargo transfer while preserving organelle identity

    Tests on the efficiency of the power plant at the Kansas State Agricultural College

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    Citation: Fockele, Glick and Cole, Murray S. Tests on the efficiency of the power plant at the Kansas State Agricultural College. Senior thesis, Kansas State Agricultural College, 1902.Morse Department of Special CollectionsIntroduction: The plant is designed to furnish heat and power for the various departments at the Kansas State Agricultural College of Manhattan, Kansas. It was originally intended by the writers to include in their work, tests on the heating power of the plant, but the arrangement of their other college work during the year, made it impossible for them to conduct the experiments at a time when the heating plant was in operation. Another drawback was the absence of suitable apparatus for the determination of the calorific power of the coal. The heating plant consists of six externally fired, horizontal, multitubular boilers, designated as No. 1, 2, 3, 4, 5 and 6. Five are of 60 nominal horsepower and one, No. 6, is of 100 nominal horsepower. The tests were conducted upon No. 1, for the reason that it was the only high pressure boiler which was piped for individual feed water, and with this boiler is our interest concerned. None of the connections with other boilers could possibly affect results of these tests except in the test on April 28th, when No. 3 was turned in on account of the heavy load on the engine. In this case neither boiler made more steam than the engine could use, so the pressure in neither one was affected in the least and the conditions of the test were kept uniform. The boiler itself is 54” diameter, with 34 flues 3-3/4 inches in diameter and 16 feet long. The grates are 4-1/2’ by 4-1/2’. The boiler was built by Joseph Bromich of Topeka, Kansas. It was installed in 1896. It was in very good condition for all tests. The fuel used was the coal furnished by the state for use in the institution, and was of very poor quality. It comes from the state mines near Leavenworth, and is mined by the prisoners from the state penitentiary

    Multi-decade changes in pollen season onset, duration, and intensity: a concern for public health?

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    Longitudinal shifts in pollen onset, duration, and intensity are public health concerns for the growing number of individuals with pollen sensitization. National analyses of long-term pollen changes are influenced by how a plant's main pollen season (MPS) is defined. Prior Swiss studies have inconsistently applied MPS definitions, leading to heterogeneous conclusions regarding the magnitude, directionality, and significance of multi-decade pollen trends. We examined national pollen data in Switzerland between 1990 and 2020, applying six MPS definitions (2 percentage-based and 4 threshold-based) to twelve relevant allergenic plants. We analyzed changes in pollen season using both linear regression and locally estimated scatterplot smoothing (LOESS). For 4 of the 12 plant species, there is unanimity between definitions regarding earlier onset of pollen season (p < 0.05), with magnitude of 31-year change dependent on specific MPS definition (hazel: 9-18 days; oak: 5-13 days; grasses: 8-25 days; and nettle/hemp: 6-25 days). There is also consensus (p < 0.05) for modified MPS duration among hazel (21-104% longer), nettle/hemp (8-52% longer), and ash (18-38% shorter). Between-definition agreement is highest for MPS intensity analysis, with consensus for significant increases in seasonal pollen quantity (p < 0.05) among hazel, birch, oak, beech, and nettle/hemp. The largest relative intensification is noted for hazel (110-146%) and beech (162-237%). LOESS analysis indicates that these multi-decade pollen changes are typically nonlinear. The robustness of MPS definitions is highly dependent on annual pollen accumulation, with definition choice particularly influential for long-term analysis of low-pollen plants such as ragweed. We identify systematic differences between MPS definitions and suggest future aerobiologic studies apply multiple definitions to minimize bias. In summary, national pollen onset, duration, and intensity have shifted for some plants in Switzerland, with MPS definition choice affecting magnitude and significance of these variations. Future public health research can determine whether these temporal and quantitative pollen changes correlate with longitudinal differences in population pollen sensitization

    Bartholin's gland cyst and abscess treatment

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    This issue of eMedRef provides information to clinicians on resolving Bartholin's gland cysts and treatment of Bartholin's gland abscess

    A Role for Actin, Cdc1p, and Myo2p in the Inheritance of Late Golgi Elements in \u3cem\u3eSaccharomyces cerevisiae\u3c/em\u3e

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    In Saccharomyces cerevisiae, Golgi elements are present in the bud very early in the cell cycle. We have analyzed this Golgi inheritance process using fluorescence microscopy and genetics. In rapidly growing cells, late Golgi elements show an actin-dependent concentration at sites of polarized growth. Late Golgi elements are apparently transported into the bud along actin cables and are also retained in the bud by a mechanism that may involve actin. A visual screen for mutants defective in the inheritance of late Golgi elements yielded multiple alleles of CDC1. Mutations in CDC1 severely depolarize the actin cytoskeleton, and these mutations prevent late Golgi elements from being retained in the bud. The efficient localization of late Golgi elements to the bud requires the type V myosin Myo2p, further suggesting that actin plays a role in Golgi inheritance. Surprisingly, early and late Golgi elements are inherited by different pathways, with early Golgi elements localizing to the bud in a Cdc1p- and Myo2p-independent manner. We propose that early Golgi elements arise from ER membranes that are present in the bud. These two pathways of Golgi inheritance in S. cerevisiae resemble Golgi inheritance pathways in vertebrate cells
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