973 research outputs found
Intrinsic gap and exciton condensation in the nu_T=1 bilayer system
We investigate the quasiparticle excitation of the bilayer quantum Hall (QH)
system at total filling factor in the limit of
negligible interlayer tunneling under tilted magnetic field. We show that the
intrinsic quasiparticle excitation is of purely pseudospin origin and solely
governed by the inter- and intra-layer electron interactions. A model based on
exciton formation successfully explains the quantitative behavior of the
quasiparticle excitation gap, demonstrating the existence of a link between the
excitonic QH state and the composite fermion liquid. Our results provide a new
insight into the nature of the phase transition between the two states.Comment: 4 pages, 3 figure
Oral information in orthopaedics: How should the patient's understanding be assessed?
AbstractIntroductionPatient information is governed by recommendations of best practices required from any healthcare professional. The aim of this study was to design a tool to measure patient comprehension of the information provided during a surgical consultation before a scheduled surgery.Material and methodsThis was a single-center prospective study of 21 patients using a rating scale-type visual analog scale. Each patient was interviewed and asked to score his or her understanding of the information provided. The investigator checked the external validity of the tool using questions to assess patient's understanding level.ResultsThe results show that there is a tendency to overvalue some information (reasons for the intervention and alternatives to surgery) and that certain information is not understood (risks and complications) or not provided (postoperative follow-up).ConclusionThis study confirms that a rating scale can measure the understanding of information and there is a variation between perceived and actual understanding
Evidence of breakdown of the spin symmetry in diluted 2D electron gases
Recent claims of an experimental demonstration of spontaneous spin
polarisation in dilute electron gases \cite{young99} revived long standing
theoretical discussions \cite{ceper99,bloch}. In two dimensions, the
stabilisation of a ferromagnetic fluid might be hindered by the occurrence of
the metal-insulator transition at low densities \cite{abra79}. To circumvent
localisation in the two-dimensional electron gas (2DEG) we investigated the low
populated second electron subband, where the disorder potential is mainly
screened by the high density of the first subband. This letter reports on the
breakdown of the spin symmetry in a 2DEG, revealed by the abrupt enhancement of
the exchange and correlation terms of the Coulomb interaction, as determined
from the energies of the collective charge and spin excitations. Inelastic
light scattering experiments and calculations within the time-dependent local
spin-density approximation give strong evidence for the existence of a
ferromagnetic ground state in the diluted regime.Comment: 4 pages, 4 figures, Revte
Stability of the Excitonic Phase in Bilayer Quantum Hall Systems at Total Filling One -- Effects of Finite Well Width and Pseudopotentials --
The ground state of a bilayer quantum Hall system at with
model pseudopotential is investigated by the DMRG method. Firstly,
pseudopotential parameters appropriate for the system with finite layer
thickness are derived, and it is found that the finite thickness makes the
excitonic phase more stable. Secondly, a model, where only a few
pseudopotentials with small relative angular momentum have finite values, is
studied, and it is clarified how the excitonic phase is destroyed as
intra-layer pseudopotential becomes larger. The importance of the intra-layer
repulsive interaction at distance twice of the magnetic length for the
destruction of the excitonic phase is found.Comment: 7 pages, 7 figure
Estimating bank default with generalised extreme value regression models
The paper proposes a novel model for the prediction of bank failures, on the basis of both macroeconomic and bank-specific microeconomic factors. As bank failures are rare, in the paper we apply a regression method for binary data based on extreme value theory, which turns out to be more effective than classical logistic regression models, as it better leverages the information in the tail of the default distribution. The application of this model to the occurrence of bank defaults in a highly bank dependent economy (Italy) shows that, while microeconomic factors as well as regulatory capital are significant to explain proper failures, macroeconomic factors are relevant only when failures are defined not only in terms of actual defaults but also in terms of mergers and acquisitions. In terms of predictive accuracy, the model based on extreme value theory outperforms classical logistic regression models
The BIOMASS level 2 prototype processor : design and experimental results of above-ground biomass estimation
BIOMASS is ESA’s seventh Earth Explorer mission, scheduled for launch in 2022. The satellite will be the first P-band SAR sensor in space and will be operated in fully polarimetric interferometric and tomographic modes. The mission aim is to map forest above-ground biomass (AGB), forest height (FH) and severe forest disturbance (FD) globally with a particular focus on tropical forests. This paper presents the algorithms developed to estimate these biophysical parameters from the BIOMASS level 1 SAR measurements and their implementation in the BIOMASS level 2 prototype processor with a focus on the AGB product. The AGB product retrieval uses a physically-based inversion model, using ground-canceled level 1 data as input. The FH product retrieval applies a classical PolInSAR inversion, based on the Random Volume over Ground Model (RVOG). The FD product will provide an indication of where significant changes occurred within the forest, based on the statistical properties of SAR data. We test the AGB retrieval using modified airborne P-Band data from the AfriSAR and TropiSAR campaigns together with reference data from LiDAR-based AGB maps and plot-based ground measurements. For AGB estimation based on data from a single heading, comparison with reference data yields relative Root Mean Square Difference (RMSD) values mostly between 20% and 30%. Combining different headings in the estimation process significantly improves the AGB retrieval to slightly less than 20%. The experimental results indicate that the implemented retrieval scheme provides robust results that are within mission requirements
Effect of a 1-Year Nutritional Blend Supplementation on Plasma p-tau181 and GFAP Levels among Community-Dwelling Older Adults: A Secondary Analysis of the Nolan Trial
BACKGROUND: Observational studies and some randomized controlled trials have suggested that nutritional supplementation could be a possible intervention pathway to prevent cognitive decline and Alzheimer's disease (AD). As measuring amyloid-β and tau pathophysiology by positron emission tomography (PET) or cerebrospinal fluid (CSF) analyses may be perceived as complex, plasma versions of such biomarkers have emerged as more accessible alternatives with comparable capacity of predicting cognitive impairment. OBJECTIVES: This study aimed to evaluate the effect of a 1-year intervention with a nutritional blend on plasma p-tau181 and glial fibrillary acidic protein (GFAP) levels in community-dwelling older adults. Effects were further assessed in exploratory analyses within sub-cohorts stratified according to p-tau status (with the third tertile considered as high: ≥15.1 pg/ mL) and to apolipoprotein E (APOE) ε4 allele status. METHODS: A total of 289 participants ≥70 years (56.4% female, mean age 78.1 years, SD=4.7) of the randomized, double-blind, multicenter, placebo-controlled Nolan trial had their plasma p-tau181 assessed, and daily took either a nutritional blend (composed of thiamin, riboflavin, niacin, pantothenic acid, pyridoxine, biotin, folic acid, cobalamin, vitamin E, vitamin C, vitamin D, choline, selenium, citrulline, eicosapentaenoic acid - EPA, and docosahexaenoic acid - DHA) or placebo for 1 year. RESULTS: After 1-year, both groups presented a significant increase in plasma p-tau181 and GFAP values, with no effect of the intervention (p-tau181 between-group difference: 0.27pg/mL, 95%CI: -0.95, 1.48; p=0.665; GFAP between-group difference: -3.28 pg/mL, 95%CI: -17.25, 10.69; p=0.644). P-tau-and APOE ε4-stratified analyses provided similar findings. CONCLUSIONS: In community-dwelling older adults, we observed an increase in plasma p-tau181 and GFAP levels that was not different between the supplementation groups after one year
Effect of External Noise Correlation in Optical Coherence Resonance
Coherence resonance occurring in semiconductor lasers with optical feedback
is studied via the Lang-Kobayashi model with external non-white noise in the
pumping current. The temporal correlation and the amplitude of the noise have a
highly relevant influence in the system, leading to an optimal coherent
response for suitable values of both the noise amplitude and correlation time.
This phenomenon is quantitatively characterized by means of several statistical
measures.Comment: RevTeX, 4 pages, 7 figure
Can We Distinguish Age-Related Frailty from Frailty Related to Diseases? Data from the MAPT Study
Abstract
Background
No study has tried to distinguish subjects that become frail due to diseases (frailty related to diseases) or in the absence of specific medical events; in this latter case, it is possible that aging process would act as the main frailty driver (age-related frailty).
Objectives
To classify subjects according to the origin of physical frailty: age-related frailty, frailty related to diseases, frailty of uncertain origin, and to compare their clinical characteristics.
Materials and methods
We performed a secondary analysis of the Multidomain Alzheimer Preventive Trial (MAPT), including 195 subjects ≥70 years non-frail at baseline who became frail during a 5-year follow-up (mean age 77.8 years ± 4.7; 70% female). Physical frailty was defined as presenting ≥3 of the 5 Fried criteria: weight loss, exhaustion, weakness, slowness, low physical activity. Clinical files were independently reviewed by two different clinicians using a standardized assessment method in order to classify subjects as: "age-related frailty", "frailty related to diseases" or "frailty of uncertain origin". Inconsistencies among the two raters and cases of uncertain frailty were further assessed by two other experienced clinicians.
Results
From the 195 included subjects, 82 (42%) were classified as age-related frailty, 53 (27%) as frailty related to diseases, and 60 (31%) as frailty of uncertain origin. Patients who became frail due to diseases did not differ from the others groups in terms of functional, cognitive, psychological status and age at baseline, however they presented a higher burden of comorbidity as measured by the Cumulative Illness Rating Scale (CIRS) (8.20 ± 2.69; vs 6.22 ± 2.02 frailty of uncertain origin; vs. 3.25 ± 1.65 age-related frailty). Time to incident frailty (23.4 months ± 12.1 vs. 39.2 ± 19.3 months) and time spent in a pre-frailty condition (17.1 ± 11.4 vs 26.6 ± 16.6 months) were shorter in the group of frailty related to diseases compared to age-related frailty. Orthopedic diseases (n=14, 26%) were the most common pathologies leading to frailty related to diseases, followed by cardiovascular diseases (n=9, 17%) and neurological diseases (n = 8, 15%).
Conclusion
People classified as age-related frailty and frailty related to diseases presented different frailty-associated indicators. Future research should target the underlying biological cascades leading to these two frailty classifications, since they could ask for distinct strategies of prevention and management
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