7 research outputs found

    Factors determining DNA double-strand break repair pathway choice in G2 phase

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    Double-strand breaks in replicated genomes are repaired by non-homologous end joining (NHEJ) or homologous recombination (HR). NHEJ gets the first attempt, while HR takes over after its failure at more complex lesions or chromatin environments. These results imply repair speed as a decisive factor in pathway choice

    Tapering Canakinumab Monotherapy in Patients with Systemic Juvenile Idiopathic Arthritis in Clinical Remission: Results from an Open\u2010label, Randomized Phase IIIb/IV Study

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    Words derived from Old Norse in Sir Gawain and the Green Knight

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