60 research outputs found
Relato e análise das atividades desenvolvidas na Biblioteca Monteiro Lobato, da Escola Desdobrada da Lagoa, de 2005 a 2009
TCC (graduação em Biblioteconomia) - Universidade Federal de Santa Catarina, FlorianópolisA presente pesquisa é uma descrição e análise das atividades desenvolvidas pela bibliotecária Raquel Pacheco na Biblioteca Monteiro Lobato, que faz parte da Escola Desdobrada Retiro da Lagoa, em Florianópolis/SC. Neste trabalho de conclusão de curso foi realizada uma pesquisa qualitativa, descritiva, de estudo de caso e o ponto de partida foi uma pesquisa bibliográfica. Registrou-se as seguintes atividades realizadas pela bibliotecária: A biblioteca de Emília; o Dia do Folclore; Contando a história; Semana da Saúde Dentária; Aprendendo o significado das cores da nossa bandeira; Onde mora o livro; Higienização do acervo da nossa biblioteca; Um dia de bibliotecário e Transformações da escrita e seus suportes. Algumas destas atividades fomentaram o incentivo à leitura, a prática de bons hábitos, o conhecimento e a aprendizagem e foram premiadas pela sua importância como uma ação educativa desenvolvida. Isso demonstra que o profissional da informação pode aliar informação e ludicidade no espaço da biblioteca. Pode-se dizer que os objetivos propostos neste trabalho de conclusão de curso foram alcançados, pois todas as atividades desempenhadas pela bibliotecária Raquel e disponibilizadas pela mesma foram descritas e analisadas pela formanda. A bibliotecária demonstrou, pelas atividades desenvolvidas que a biblioteca pode ser um espaço onde as crianças aprendem se divertindo. Destacando a importância e necessidade de uma atuação criativa e dinâmica dos bibliotecários frente às suas unidade
Clusters in Various Cosmological Models: Abundance and Evolution
The combination of measurements of the local abundance of rich clusters of
galaxies and its evolution to higher redshift offers the possibility of a
direct measurement of with little contribution from other
cosmological parameters. We investigate the significance of recent claims that
this evolution indicates that must be small. The most recent cluster
velocity dispersion function from a compilation including the ESO Northern
Abell Cluster Survey (ENACS) results in a significantly higher normalization
for models, corresponding to for , compared
to the Eke, Cole, & Frenk result of . Using the ENACS
data for a calibration results in strong evolution in the abundance of
clusters, and we find that the velocity dispersion function is consistent with
. The results are dependent upon the choice and analysis of
low-redshift and high-redshift data, so at present, the data is not good enough
to determine unambiguously.Comment: 4 pages Latex using sprocl.sty, 1 figure. To appear in Proceedings of
12th Potsdam Cosmology Workshop, "Large-Scale Structure: Tracks and Traces"
Sept. 15-19, 199
Lesão por pressão em unidade de terapia intensiva: prevalência e fatores associados em pacientes COVID-19
Objetivo: Determinar a ocorrência de lesões por pressão e identificar fatores de risco associados em pacientes acometidos pela COVID-19 internados em unidade de terapia intensiva.Método: Estudo transversal, retrospectivo com abordagem quantitativa realizado por meio pesquisa documental. Para a amostra selecionou-se 393 prontuários que contemplaram os critérios de inclusão, no período de março de 2020 a março de 2021, de um hospital da região sul brasileira. Os dados foram analisados por meio de análise estatística descritiva, utilizou-se o programa estatístico Bioestat 5.0.Resultados: A prevalência de lesões por pressão em pacientes com COVID-19 foi de 42%, os fatores de riscos associados a lesões foram o tempo de internação, terapia ventilatória e a posição prona com significância (p<0,05).Conclusão: Pacientes com COVID-19 estão sujeitos a diversos fatores não modificáveis que são determinantes no surgimento de lesões por pressão. Portanto, infere-se que as medidas de prevenção devem ser rigorosamente aplicadas nessa população.
Palavras-chave: COVID-19. Lesão por pressão. Cuidados críticos. Enfermagem. Unidades de terapia intensiva
The epidemiology of malignant mesothelioma in women: gender differences and modalities of asbestos exposure
INTRODUCTION: The epidemiology of gender differences for mesothelioma incidence has been rarely discussed in national case lists. In Italy an epidemiological surveillance system (ReNaM) is working by the means of a national register. METHODS: Incident malignant mesothelioma (MM) cases in the period 1993 to 2012 were retrieved from ReNaM. Gender ratio by age class, period of diagnosis, diagnostic certainty, morphology and modalities of asbestos exposure has been analysed using exact tests for proportion. Economic activity sectors, jobs and territorial distribution of mesothelioma cases in women have been described and discussed. To perform international comparative analyses, the gender ratio of mesothelioma deaths was calculated by country from the WHO database and the correlation with the mortality rates estimated. RESULTS: In the period of study a case list of 21 463 MMs has been registered and the modalities of asbestos exposure have been investigated for 16 458 (76.7%) of them. The gender ratio (F/M) was 0.38 and 0.70 (0.14 and 0.30 for occupationally exposed subjects only) for pleural and peritoneal cases respectively. Occupational exposures for female MM cases occurred in the chemical and plastic industry, and mainly in the non-asbestos textile sector. Gender ratio proved to be inversely correlated with mortality rate among countries. CONCLUSIONS: The consistent proportion of mesothelioma cases in women in Italy is mainly due to the relevant role of non-occupational asbestos exposures and the historical presence of the female workforce in several industrial settings. Enhancing the awareness of mesothelioma aetiology in women could support the effectiveness of welfare system and prevention policies
The epidemiology of malignant mesothelioma in women: gender differences and modalities of asbestos exposure
ntroduction The epidemiology of gender differences
for mesothelioma incidence has been rarely discussed in
national case lists. In Italy an epidemiological surveillance
system (ReNaM) is working by the means of a national
register.
Methods Incident malignant mesothelioma (MM)
cases in the period 1993 to 2012 were retrieved from
ReNaM. Gender ratio by age class, period of diagnosis,
diagnostic certainty, morphology and modalities of
asbestos exposure has been analysed using exact
tests for proportion. Economic activity sectors, jobs
and territorial distribution of mesothelioma cases in
women have been described and discussed. To perform
international comparative analyses, the gender ratio of
mesothelioma deaths was calculated by country from the
WHO database and the correlation with the mortality
rates estimated.
Results In the period of study a case list of 21 463
MMs has been registered and the modalities of asbestos
exposure have been investigated for 16 458 (76.7%) of
them. The gender ratio (F/M) was 0.38 and 0.70 (0.14
and 0.30 for occupationally exposed subjects only) for
pleural and peritoneal cases respectively. Occupational
exposures for female MM cases occurred in the chemical
and plastic industry, and mainly in the non-asbestos
textile sector. Gender ratio proved to be inversely
correlated with mortality rate among countries.
Conclusions The consistent proportion of
mesothelioma cases in women in Italy is mainly due to
the relevant role of non-occupational asbestos exposures
and the historical presence of the female workforce in
several industrial settings. Enhancing the awareness of
mesothelioma aetiology in women could support the
effectiveness of welfare system and prevention policie
Letter concerning:‘Response to:‘The epidemiology of malignant mesothelioma in women: gender differences and modalities of asbestos exposure’by Marinaccio et al’
Finkelstein1 invited physicians and researchers interested in mesothelioma to investigate on past usage of talcum powders by affected people. In Italy, asbestos contamination in talc for industrial use has been documented,2 and, as he underlines tremolite contamination at low levels of cosmetic and pharmaceutical talc has been reported in USA by Blount3 and Gordon and colleagues.4
In the Italian National Mesothelioma Register (ReNaM), the analysis of intensive exposure to talc has been evaluated with respect to occupational and environmental history. The catalogue of possible asbestos exposure circumstances (a tool for the interviewers) reports the potential presence of industrial talcs in quarries or mines working activities, in leather tanning and in rubber industries. The use of intensive cosmetic talc for personal use is evaluated by means of a structured questionnaire,5 as reported in the ReNaM guidelines (see https://www.inail.it/cs/internet/docs/all-linee-guida-renam.pdf?section=attivita, p82, p98, in Italian).
In our paper regarding gender differences in mesothelioma epidemiology,6 we have presented figures referring to 21 463 MM cases detected by ReNaM with a diagnosis between 1993 and 2012. Among female case list (6087 cases), 4374 cases (71.9%) have been interviewed for defining exposure. During the interview, 30 MM female cases referred an intensive use of talc in the context of occupational or life habits. For five of them, the regional centre has identified an exposure to asbestos due to intensive talc use, classifying such modality of exposure as ‘leisure activities’ (see ReNaM guidelines5). For the remaining 25 cases, an occupational exposure to asbestos in other working (or familiar or environmental) circumstances has been identified and coded.
Registry data such as those provided by ReNaM cannot provide estimates of the mesothelioma risk associated with any particular exposure circumstance. We plan to include talc exposure at work and cosmetic talc usage in the analyses of a case–control study on pleural mesothelioma currently under way. A specific survey to compare and discuss how the modalities of exposure to talc have been evaluated in patients with mesothelioma in countries where epidemiological surveillance systems are active could improve knowledge and support prevention policies
Observational Mass-to-Light Ratio of Galaxy Systems: from Poor Groups to Rich Clusters
We study the mass-to-light ratio of galaxy systems from poor groups to rich
clusters, and present for the first time a large database for useful
comparisons with theoretical predictions. We extend a previous work, where B_j
band luminosities and optical virial masses were analyzed for a sample of 89
clusters. Here we also consider a sample of 52 more clusters, 36 poor clusters,
7 rich groups, and two catalogs, of about 500 groups each, recently identified
in the Nearby Optical Galaxy sample by using two different algorithms. We
obtain the blue luminosity and virial mass for all systems considered. We
devote a large effort to establishing the homogeneity of the resulting values,
as well as to considering comparable physical regions, i.e. those included
within the virial radius. By analyzing a fiducial, combined sample of 294
systems we find that the mass increases faster than the luminosity: the linear
fit gives M\propto L_B^{1.34 \pm 0.03}, with a tendency for a steeper increase
in the low--mass range. In agreement with the previous work, our present
results are superior owing to the much higher statistical significance and the
wider dynamical range covered (about 10^{12}-10^{15} M_solar). We present a
comparison between our results and the theoretical predictions on the relation
between M/L_B and halo mass, obtained by combining cosmological numerical
simulations and semianalytic modeling of galaxy formation.Comment: 25 pages, 12 eps figures, accepted for publication in Ap
Puzzling large-scale polarization in the galaxy cluster Abell 523
Large-scale magnetic fields reveal themselves through diffuse synchrotron
sources observed in galaxy clusters such as radio halos. Total intensity
filaments of these sources have been observed in polarization as well, but only
in three radio halos out of about one hundred currently known. In this paper we
analyze new polarimetric Very Large Array data of the diffuse emission in the
galaxy cluster Abell 523 in the frequency range 1-2 GHz. We find for the first
time evidence of polarized emission on scales of ~ 2.5 Mpc. Total intensity
emission is observed only in the central part of the source, likely due to
observational limitations. To look for total intensity emission beyond the
central region, we combine these data with single-dish observations from the
Sardinia Radio Telescope and we compare them with multi-frequency total
intensity observations obtained with different instruments, including the LOw
Frequency ARray and the Murchison Widefield Array. By analysing the rotation
measure properties of the system and utilizing numerical simulations, we infer
that this polarized emission is associated with filaments of the radio halo
located in the outskirts of the system, in the peripheral region closest to the
observer.Comment: 14 pages, 12 figures, accepted for publication on MNRA
Os efeitos de dois modelos de treino de ginástica localizada sobre a composição corporal, a força e a resistência muscular
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Neutralizing activity and T Cell response after bivalent fifth dose of mRNA vaccine in person living with HIV
OBJECTIVES: To investigate immunogenicity of SARS-CoV-2 vaccine third booster (3BD; fifth dose) with bivalent vaccine original/BA4/5 vaccine in people living with HIV (PLWH). STUDY DESIGN: This is an observational cohort study to evaluate the outcomes of SARS-CoV-2 vaccination (HIV-VAC study). We analyzed microneutralization assay and IFN-γ production in 48 PLWH on ART with CD4 count <200 cell/mm3 and/or previous AIDS according to immunization status: vaccinated PLWH who had a previous SARS-CoV-2 infection (hybrid immunization, HI) vs. those only vaccinated (non-hybrid immunization, nHI) and current CD4 count RESULTS: After 15 days from its administration (T1), the 3BD bivalent mRNA vaccine elicited a statistically significant increase of neutralizing antibodies (nAbs) geometric mean titers (GMTs) from T0 to T1 against W-D614G (fold-increase 4.8; p<0.0001), BA.5 (8.6 p<0.0001), BQ.1.1 (6.4, p<0.0001) and XBB.1 (6.5, p<0.0001). When compared to BA.5, nAbs GMTs against BQ.1.1 and XBB.1 decreased by 3.5 and 4.1-fold, respectively. After controlling for age, years from AIDS diagnosis, CD4 count at administration and CD4 count nadir, the fold change reduction in nAbs response to other VoCs as compared to BA.1, was larger in participants with HI vs. those nHI: 0.59 lower (95%CI 0.36, 0.97, p=0.04) for BQ.1.1 and 0.67 lower (95% CI: 0.47, 0.96, p=0.03) for XBB.1.In contrast, the analysis carried little evidence for an association between current CD4 count and response to the fifth dose of bivalent vaccine. Furthermore, cell-mediated immunity remained stable. CONCLUSIONS: Our data support the current recommendation of offering bivalent mRNA vaccine booster doses to PLWH with low CD4 count or previous AIDS at first vaccination, especially in those who never previously acquired SARS CoV2 and regardless of current CD4 count
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