Modeling Functional Limitations, Gait Impairments, and Muscle Pathology in Alzheimer’s Disease: Studies in the 3xTg-AD Mice

Frailty; Muscular strength; Translational neuroscienceFragilidad; Fuerza muscular; Neurociencia traslacionalFragilitat; Força muscular; Neurociència translacionalGait impairments in Alzheimer’s disease (AD) result from structural and functional deficiencies that generate limitations in the performance of activities and restrictions in individual’s biopsychosocial participation. In a translational way, we have used the conceptual framework proposed by the International Classification of Disability and Health Functioning (ICF) to classify and describe the functioning and disability on gait and exploratory activity in the 3xTg-AD animal model. We developed a behavioral observation method that allows us to differentiate qualitative parameters of psychomotor performance in animals’ gait, similar to the behavioral patterns observed in humans. The functional psychomotor evaluation allows measuring various dimensions of gait and exploratory activity at different stages of disease progression in dichotomy with aging. We included male 3xTg-AD mice and their non-transgenic counterpart (NTg) of 6, 12, and 16 months of age (n = 45). Here, we present the preliminary results. The 3xTg-AD mice show more significant functional impairment in gait and exploratory activity quantitative variables. The presence of movement limitations and muscle weakness mark the functional decline related to the disease severity stages that intensify with increasing age. Motor performance in 3xTg-AD is accompanied by a series of bizarre behaviors that interfere with the trajectory, which allows us to infer poor neurological control. Additionally, signs of physical frailty accompany the functional deterioration of these animals. The use of the ICF as a conceptual framework allows the functional status to be described, facilitating its interpretation and application in the rehabilitation of people with AD.This work was funded by 2017-SGR-1468 and UAB-GE-260408 to L.G.-L. The colony of 3xTg-AD mice is sustained by ArrestAD H2020 Fet-OPEN-1-2016-2017-737390, European Union’s Horizon 2020 research and innovation program under grant agreement No 737390 to L.G.-L. It also received financial support from Memorial Mercedes Llort Sender 2021/80/09241941.8

Subjective assessment of university classroom environment

[EN] Research into the design of learning environments is warranted as the classroom space impacts on students' wellbeing and learning performance. Studies on subjective evaluation of classrooms usually focus on the influence of more objective aspects like temperature, light, sound, etc., based on concepts or attributes defined by experts. Thus, the attributes used to find relations with design parameters might not be recognised by users, thereby conditioning the evaluation process itself. This paper aims to analyse students' affective response to a university classroom in their own words, and then, after obtaining the semantic space, to identify the design elements that generate a positive affective response. This analysis was carried out implementing the Semantic Differential method in the framework of Kansei Engineering. A sample of 918 university students was assessed in situ in 30 university classrooms. The results show that students' affective structure in relation to their classroom comprises six independent factors: functionality and layout, cosy and pleasant, concentration and comfort, modern design, daylight and outward facing, and artificial lighting. From these factors, efforts to improve the classroom environment should be directed mainly towards two aspects: improving classroom functionality-layout, which is significantly related to the work space allocated to students; and the sensation of cosy-pleasant which is generated by all the classroom design parameters, but in particular, those that refer to the relationship of the classroom with the outdoor environment.This research was supported by Ministerio de Economia y Competitividad, Spain (project TIN2013-45736-R)Castilla-Cabanes, N.; Llinares Millán, MDC.; Bravo, JM.; Blanca Giménez, V. (2017). Subjective assessment of university classroom environment. Building and Environment. 122:72-81. https://doi.org/10.1016/j.buildenv.2017.06.004S728112

LLAMA Project

LLAMA, acronymum of Long Latin American Millimetre Array, is a joint scientific and technological undertaking of Argentina and Brazil whose main goal is to install and to operate a 12m dish capable of studyingthe Universe at millimetre and sub-millimetre wavelengths.This facility will be erected in the norwestern part of Argentina, some 20 km away from the town of San Antonio de los Cobres (Salta province), at a site located 4830m above sea level. In this presentation we would like to formally introduce this project to the Latin American astronomical community by briefly describing its current status.Besides working as a stand alone instrument (or single dish mode), this radiometer may also become part of a local network of Very Long Baseline Interferometry (VLBI) that may be integrated by existing telescopes like APEX, ASTE, Itapetinga and some of the ALMA dishes. In its way, this VLBI network may be able to increase the resolving power of ALMA by an order of magnitude.The construction phase of this facility is being financed by Ministerio de Ciencia, Tecnología e Innovación Productiva (MINCyT, Argentina) and Fundacao de Amparo á Pesquisa do Estado de Sao Paulo (FAPESP), on the basis of an equal investment share.Fil: Arnal, Edmundo Marcelo. Provincia de Buenos Aires. Gobernación. Comisión de Investigaciones Científicas. Instituto Argentino de Radioastronomía. Consejo Nacional de Investigaciones Científicas y Técnicas. Centro Científico Tecnológico Conicet - La Plata. Instituto Argentino de Radioastronomía; ArgentinaFil: Abraham, Zulema. Universidade do Sao Paulo. Instituto de Astronomia, Geofísica e Ciências Atmosféricas; BrasilFil: Giménez de Castro, Guillermo. Universidade Presbiteriana Mackenzie; BrasilFil: Gouveia dal Pino, E. M. de. Universidade do Sao Paulo. Instituto de Astronomia, Geofísica e Ciências Atmosféricas; BrasilFil: Larrarte, Juan Jose. Provincia de Buenos Aires. Gobernación. Comisión de Investigaciones Científicas. Instituto Argentino de Radioastronomía. Consejo Nacional de Investigaciones Científicas y Técnicas. Centro Científico Tecnológico Conicet - La Plata. Instituto Argentino de Radioastronomía; ArgentinaFil: Lepine, Jacques. Universidade do Sao Paulo. Instituto de Astronomia, Geofísica e Ciências Atmosféricas; BrasilFil: Morras, Ricardo. Provincia de Buenos Aires. Gobernación. Comisión de Investigaciones Científicas. Instituto Argentino de Radioastronomía. Consejo Nacional de Investigaciones Científicas y Técnicas. Centro Científico Tecnológico Conicet - La Plata. Instituto Argentino de Radioastronomía; ArgentinaFil: Viramonte, Jose Maria. Universidad Nacional de Salta. Facultad de Ciencias Naturales. Instituto Geonorte; ArgentinaXIV Latin American Regional IAU meetingFlorianapolisBrasilUniversidade Federal de Santa Catarin

The Long Latin American Millimeter Array: a new submillimeter facility to observe the Sun

The Long Latin American Millimeter Array (LLAMA), is an Argentinian - Brazilian project to build and operate a 12-m radiotelescope that may observe from 45 to 900 GHz and that will have VLBI capabilities. LLAMA will be installed in the Argentinian "Puna de Atacama" region at 4800 m above see level in the Salta Province, at less than 200 km distance from ALMA. The site has excellent sky transmission characteristics for submillimeter astronomy. LLAMA may observein single dish mode, or as VLBI station associated to ALMA at submillimeter wavelengths or to other telescopes at microwaves. Since it is a multipurpose observatory,it has within its objectives,observing the Sun. In VLBI mode it will have a resolution better than 0.001 arcsec at 1 mm wavelength, bringing unprecedented images of the solar atmosphere with a spatial resolution of the order of 1 km. In single dish mode, it will complement spectral observations already carry out by other telescopes. Key aspects to be addressed by solar LLAMA observations are: i) low atmosphere structure, ii) filaments, iii) dynamics of the chromosphere and its magnetic field and iv) flares. The project received full financial support from the Brazilian Agency FAPESP and the Argentinian Ministry of Science for the installation and operation of the antenna near thetown of San Antonio de los Cobres, and should have its first light by beginning 2015, expecting to start early science on middle 2016. We detail in this work the technical features of LLAMA, its state of advance and the science that may be done with its observations.Fil: Giménez de Castro, Guillermo C.. Universidade Presbiteriana Mackenzie; BrasilFil: Abraham, Zulema. Universidade do Sao Paulo. Instituto de Astronomia, Geofísica e Ciências Atmosféricas; BrasilFil: Arnal, Edmundo Marcelo. Provincia de Buenos Aires. Gobernación. Comisión de Investigaciones Científicas. Instituto Argentino de Radioastronomía. Consejo Nacional de Investigaciones Científicas y Técnicas. Centro Científico Tecnológico Conicet - La Plata. Instituto Argentino de Radioastronomía; ArgentinaFil: Gouveia Dal Pino, Elizabete de. Universidade do Sao Paulo. Instituto de Astronomia, Geofísica e Ciências Atmosféricas; BrasilFil: Larrarte, Juan Jose. Provincia de Buenos Aires. Gobernación. Comisión de Investigaciones Científicas. Instituto Argentino de Radioastronomía. Consejo Nacional de Investigaciones Científicas y Técnicas. Centro Científico Tecnológico Conicet - La Plata. Instituto Argentino de Radioastronomía; ArgentinaFil: Lepine, Jacques. Universidade do Sao Paulo. Instituto de Astronomia, Geofísica e Ciências Atmosféricas; BrasilFil: Morras, Ricardo. Provincia de Buenos Aires. Gobernación. Comisión de Investigaciones Científicas. Instituto Argentino de Radioastronomía. Consejo Nacional de Investigaciones Científicas y Técnicas. Centro Científico Tecnológico Conicet - La Plata. Instituto Argentino de Radioastronomía; ArgentinaFil: Viramonte, Jose Maria. Universidad Nacional de Salta. Facultad de Ciencias Naturales. Instituto Geonorte; Argentina2nd Solar ALMA WorkshopPragaRepública ChecaAcademy of Sciences of the Czech Republic. Astronomical Institut

Assessment of the potential value of plasma Torque Teno virus DNA load monitoring to predict cytomegalovirus DNAemia in patients with hematological malignancies treated with small molecule inhibitors: A proof-of-concept study

T-cells; Ibrutinib; DNA loadCélulas T; Ibrutinib; Carga de ADNCèl·lules T; Ibrutinib; Càrrega d'ADNIt is unknown whether Torque Teno virus (TTV) DNA load monitoring could anticipate the development of infectious events in hematological patients undergoing treatment with small molecular targeting agents. We characterized the kinetics of plasma TTV DNA in patients treated with ibrutinib or ruxolitinib and assessed whether TTV DNA load monitoring could predict the occurrence of Cytomegalovirus (CMV) DNAemia or the magnitude of CMV-specific T-cell responses. Multicenter, retrospective, observational study, recruiting 20 patients treated with ibrutinib and 21 with ruxolitinib. Plasma TTV and CMV DNA loads were quantified by real-time PCR at baseline and days +15, +30, +45, +60, +75, +90, +120, +150, and +180 after treatment inception. Enumeration of CMV-specific interferon-γ (IFN-γ)-producing CD8+ and CD4+ T-cells in whole blood was performed by flow cytometry. Median TTV DNA load in ibrutinib-treated patients increased significantly (p = 0.025) from baseline (median: 5.76 log10 copies/mL) to day +120 (median: 7.83 log10 copies/mL). A moderate inverse correlation (Rho = −0.46; p < 0.001) was found between TTV DNA load and absolute lymphocyte count. In ruxolitinib-treated patients, TTV DNA load quantified at baseline was not significantly different from that measured after treatment inception (p ≥ 0.12). TTV DNA load was not predictive of the subsequent occurrence of CMV DNAemia in either patient group. No correlation was observed between TTV DNA loads and CMV-specific IFN-γ-producing CD8+ and CD4+ T-cell counts in either patient group. The data did not support the hypothesis that TTV DNA load monitoring in hematological patients treated with ibrutinib or ruxolitinib could be useful to predict either the occurrence of CMV DNAemia or the level of CMV-specific T-cell reconstitution; nevertheless, due to the small sample size, further studies involving larger cohorts are warranted to elucidate this issue.Estela Giménez (Juan Rodés Contract, JR18/00053) and Eliseo Albert (Juan Rodés Contract; JR20/00011) hold contracts funded by the Carlos III Health Institute (co-financed by the European Regional Development Fund, ERDF/FEDER). This research was supported by a grant from FIS PI18/00127 (Fondo de Investigaciones Sanitarias), Ministerio de Sanidad y Consumo, Spain)

The influence of oxygen concentration during embryo culture on obstetric and neonatal outcomes: a secondary analysis of a randomized controlled trial.

STUDY DESIGN, SIZE, DURATION: A secondary analysis of a previous randomized controlled trial assessing clinical pregnancy outcomes was carried out. This analysis included 1125 consecutive oocyte donation cycles utilizing ICSI or IVF and Day 3 embryo transfers between November 2009 and April 2012. The whole cohort of donated oocytes from patients who agreed to participate in the study were randomly allocated (1:1 ratio) to a reduced O2 tension group (6% O2) or an air-exposed group (20% O2) based on a computergenerated randomization list. Fresh and vitrified oocytes were used for oocyte donation. Only those pregnancies with a live birth at or beyond 24 weeks of gestation were included. PARTICIPANTS/MATERIALS, SETTING, METHODS: Day 3 embryos were cultured in an atmosphere of 5.5% CO2, 6% O2, 88.5% N2 versus a dual gas system in air. MAIN RESULTS AND THE ROLE OF CHANCE: From the eligible 1125 cycles, 564 were allocated to the 6% O2 group and 561 cycles to the 20% O2 group. However, 50 and 62 cycles did not reach embryo transfer in the 6% and 20% O2 groups, respectively. No differences were found between 6% O2 and atmospheric O2 tension in the number of livebirths per embryo transfer (mean § SD, 0.5 § 0.7 versus 0.5 § 0.7), pregnancy complications or neonatal outcomes. Both groups (6% and atmospheric O2) had similar single and twin delivery rates (40.8% versus 38.1% and 10.7% versus 12.3%, respectively). Preterm delivery rates and very preterm delivery rates (10.80% versus 13.24% and 1.25% versus 2.94%, respectively), birthweight (3229 § 561 g versus 3154 § 731 g), low birthweight (2.92% versus 2.45%), birth height (50.18 § 2.41 cm versus 49.7 § 3.59 cm), head circumference (34.16 § 1.87 cm versus 33.09 § 1.85 cm) and 1 min Apgar scores (8.96 § 0.87 versus 8.89 § 0.96) were also similar between 6% and atmospheric O2 groups, respectively. LIMITATIONS, REASONS FOR CAUTION: The number of liveborns finally analyzed is still small and not all obstetric and neonatal variables could be evaluated. Furthermore, a small proportion of the obstetric and neonatal data was obtained through a questionnaire VC The Author(s) 2020. Published by Oxford University Press on behalf of European Society of Human Reproduction and Embryology. All rights reserved. For permissions, please email: [email protected] Human Reproduction, Vol.0, No.0, pp. 1-14, 2020 doi:10.1093/humrep/deaa152 One reason for the lack of effect of oxygen concentration on pregnancy outcome could be the absence of trophectoderm cells at cleavage stage, which may make Day 3 embryos less susceptible to hypoxic conditions. WIDER IMPLICATIONS OF THE FINDINGS: Nowadays many IVF laboratories use a more physiological oxygen concentration for embryo culture. However, the benefits of using low oxygen concentration on both laboratory and clinical outcomes during embryo culture are still under debate. Furthermore, long-term studies investigating the effect of using atmospheric O2 are also needed. Gathering these type of clinical data is indeed, quite relevant from the safety perspective. The present data show that, at least in egg donation cycles undergoing Day 3 embryo transfers, culturing embryos under atmospheric oxygen concentration seems not to affect perinatal outcome

Grain quality as Influenced by the structural properties of weed communities in Mediterranean wheat crops

Weed community structure, including composition, taxonomic and functional diversity, may explain variability in crop quality, adding to the variability accounted by management, climatic and genetic factors. Focusing on Mediterranean rainfed wheat crops, we sampled weed communities from 26 fields in Spain that were either organically or conventionally managed. Weed communities were characterized by their abundance and taxonomic, compositional and trait-based measures. Grain protein concentration and the glutenin to gliadin ratio were used as indicators of wheat grain quality. Linear mixed effects models were used to analyze the relationship between crop quality and weed community variables, while accounting for environmental factors. Nitrogen fertilization, previous crop and precipitation explained a large portion of the variation in wheat grain protein concentration (R2marginal = 0.39) and composition (R2marginal = 0.26). Weed community measures had limited effects on grain quality (increasing R2marginal of models by 1% on average). The weed effects were related to the composition and the functional structure of their communities, but not to their abundance. Environmental conditions promoting higher protein concentration were also selecting for weed species with competitive attributes, whereas the role of weed functional diversity depended on the functional trait and on the resource limiting crop grain quality. Understanding the mechanisms of weed effects on crop quality could aid on designing sustainable weed management practices.This research was supported by grants AGL2012-33736 and AGL2015-64130-R funded by MCIN/AEI/10.13039/501100011033 and by “ERDF A way of making Europe”. D.J.G. was partially supported by the United States National Science Foundation (DUE 1758497 and DUE 1949969)Postprint (published version

Impacto del cultivo de soja sobre tierras desmontadas en la provincia del Chaco

PósterEl proceso de agriculturización, en el oeste del Chaco, está reemplazando el bosque nativo por el monocultivo de soja bajo siembra directa (SD). Los objetivos de este trabajo fueron evaluar el impacto del monocultivo de soja sobre variables físicas, químicas y productivas de diferentes suelos recientemente desmontados en el Dpto. Almirante Brown, y crear un modelo de simulación experto para optimizar la toma de decisiones.EEA Sáenz PeñaFil: Lopez, Astor Emilio. Instituto Nacional de Tecnología Agropecuaria (INTA). Estación Experimental Agropecuaria Sáenz Peña; ArgentinaFil: Roldan, Maria Florencia. Instituto Nacional de Tecnología Agropecuaria (INTA). Estación Experimental Agropecuaria Sáenz Peña; ArgentinaFil: Zurita, Juan José. Instituto Nacional de Tecnología Agropecuaria (INTA). Estación Experimental Agropecuaria Sáenz Peña; ArgentinaFil: Brest, Elías Francisco. Instituto Nacional de Tecnología Agropecuaria (INTA). Estación Experimental Agropecuaria Sáenz Peña; ArgentinaFil: Giménez, Laura Itatí. Universidad Nacional del Nordeste. Facultad de Ciencias Agrarias; ArgentinaFil: Montico, Sergio. Universidad Nacional de Rosario. Facultad de Ciencias Agrarias; Argentin

Biopolímeros y Nanotecnología: Desde el Laboratorio a la Planta Piloto

El desarrollo de nuevas formulaciones basadas en nano-biocompuestosbiodegradables es una temática de actualidad en función del cuidado del medio ambiente. El trabajo comenzó con la solicitud de una empresa Pyme transformadora de plástico que produce envases para el agro y consistió en la fabricación de películas para bolsas biodegradables en tierra. A nivel laboratorio, se obtuvieron películas por medio de casting usando diferentes formulaciones a base de almidón mezclándolo con otro biopolímero y agregando a la mezcla diferentes porcentajes de nanocelulosa bacteriana (NCB) y de nanoarcilla (NA). Para la fabricación de prototipos de bolsas se elegían las que formaran película y se biodegradaran en tierra. En la etapa de Planta Piloto, se usó una extrusora de simple tornillo y un equipo de extrusión-soplado. Se estudiaron las condiciones óptimas de procesamiento para obtener una burbuja estable. Luego de lo cual, estas películas en forma de tubos fueron caracterizadas mecánicamente y por biodegradación en suelo. En cuanto a la fabricación de nanocelulosa bacteriana, que fue uno de los aditivos usados, también se trabajó con otra empresa Pyme Primero estudiando el proceso en el laboratorio: la materia prima de partida, tipos de fermentadores y las condiciones óptimas del proceso. Para luego pasar a la etapa de planta piloto y su transferencia a una empresa.En estos dos trabajos de transferencia de tecnología se utilizaron los conocimientos adquiridos luego de muchos años de investigación junto con los conocimientosfundamentales adquiridos en las carreras de Ingeniería.Fil: Vazquez, Analia. Universidad de Buenos Aires; ArgentinaFil: Foresti, Maria Laura. Consejo Nacional de Investigaciones Científicas y Técnicas. Oficina de Coordinación Administrativa Houssay. Instituto de Tecnología en Polímeros y Nanotecnología. Universidad de Buenos Aires. Facultad de Ingeniería. Instituto de Tecnología en Polímeros y Nanotecnología; ArgentinaFil: Cerrutti, Patricia. Universidad de Buenos Aires; ArgentinaFil: Melaj, Mariana. Consejo Nacional de Investigaciones Científicas y Técnicas. Oficina de Coordinación Administrativa Houssay. Instituto de Tecnología en Polímeros y Nanotecnología. Universidad de Buenos Aires. Facultad de Ingeniería. Instituto de Tecnología en Polímeros y Nanotecnología; ArgentinaFil: Leonardi, Luciano. Consejo Nacional de Investigaciones Científicas y Técnicas. Oficina de Coordinación Administrativa Houssay. Instituto de Tecnología en Polímeros y Nanotecnología. Universidad de Buenos Aires. Facultad de Ingeniería. Instituto de Tecnología en Polímeros y Nanotecnología; ArgentinaFil: Giménez, Rocío Belén. Consejo Nacional de Investigaciones Científicas y Técnicas. Oficina de Coordinación Administrativa Houssay. Instituto de Tecnología en Polímeros y Nanotecnología. Universidad de Buenos Aires. Facultad de Ingeniería. Instituto de Tecnología en Polímeros y Nanotecnología; ArgentinaFil: Principe Lopez, Nazareno. Consejo Nacional de Investigaciones Científicas y Técnicas. Oficina de Coordinación Administrativa Houssay. Instituto de Tecnología en Polímeros y Nanotecnología. Universidad de Buenos Aires. Facultad de Ingeniería. Instituto de Tecnología en Polímeros y Nanotecnología; ArgentinaFil: Rodriguez Batller, Maria Jose. Consejo Nacional de Investigaciones Científicas y Técnicas. Oficina de Coordinación Administrativa Houssay. Instituto de Tecnología en Polímeros y Nanotecnología. Universidad de Buenos Aires. Facultad de Ingeniería. Instituto de Tecnología en Polímeros y Nanotecnología; ArgentinaFil: Fernandez Corujo, Victoria. Consejo Nacional de Investigaciones Científicas y Técnicas. Oficina de Coordinación Administrativa Houssay. Instituto de Tecnología en Polímeros y Nanotecnología. Universidad de Buenos Aires. Facultad de Ingeniería. Instituto de Tecnología en Polímeros y Nanotecnología; ArgentinaFil: Bernal, Celina. Consejo Nacional de Investigaciones Científicas y Técnicas. Oficina de Coordinación Administrativa Houssay. Instituto de Tecnología en Polímeros y Nanotecnología. Universidad de Buenos Aires. Facultad de Ingeniería. Instituto de Tecnología en Polímeros y Nanotecnología; Argentina5° Congreso Argentino de Ingeniería; 11° Congreso Argentino de Enseñanza de la Ingeniería y 3° Congreso Latinoamericano de IngenieríaCiudad Autónoma de Buenos AiresArgentinaUniversidad de Buenos Aires. Facultad de IngenieríaConsejo Federal de Decanos de Ingeniería de la República Argentin

FGROUP in the social and healthcare market

[EN] As part of its diversification strategy, FGROUP intends to get into the social and health care market, which shows a very high growth potential due to demographic and social causes. To tackle this strategy, IBV proposed to define FGROUP¿s business model in this new market using the tools Business Model Canvas by Osterwalder et al and Business Model Tracker by IBV. These tools were used as a means of analysis of the evolution in firm¿s capabilities and the state of the environment to obtain sustainable competitive advantages. As a consequence of this analysis, a new product in line with the business model was developed to help in its implementation.[ES] FGROUP pretende entrar en el FGROUP en el mercado sociosanitario mercado sociosanitario como parte de su estrategia de diversificación. Este mercado presenta un potencial de crecimiento muy elevado a nivel mundial debido, entre otras, a causas demográficas y socioeconómicas. Para abordar esta estrategia, el Instituto de Biomecánica (IBV) propuso definir un modelo de negocio en este nuevo mercado empleando las herramientas Business Model Canvas de Osterwalder y Business Model Tracker del IBV. Estas herramientas se utilizaron como medios de análisis de la evolución de las capacidades de la empresa y del estado del entorno para obtener ventajas competitivas sostenibles. Como consecuencia de este análisis, se llevó a cabo el desarrollo de un producto coherente con el modelo de negocio diseñado, que ayudará a ponerlo en práctica.Proyecto financiado en el marco de la convocatoria de los II Planes Sectoriales de Competitividad 2009, dentro de la Actuación 2.6: Diseño, 2.6.2 Prestación de servicios de asesoramiento. Proyecto cofinanciado por los ÇFondos FEDER, dentro del Programa Operativo FEDER de la Comunidad Valenciana 2007-2013Giménez Pla, JF.; Aparisi Hermoso, P.; López Vicente, MA.; Sancho Mollá, M.; Navarro Garcia, FJ.; Gamón Sanz, A.; García Muñoz, N.... (2013). FGROUP en el mercado sociosanitario. Revista de biomecánica. 60:25-27. http://hdl.handle.net/10251/38673S25276