35,994 research outputs found
Eudaimonic Pathways of Activating Compassion Reduce Vulnerabilities to Paranoia
This study aimed to identify if compassion benefits paranoia and, if so what type of compassion. Following a series of different compassionate exercises in 104 participants it was found that mindfulness approaches were the most significant in reducing paranoia suggesting a new approach for psychological problems characterised by paranoia
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Mediated intimacy: Sex advice in media culture
The bold argument of Mediated Intimacy (Barker et al., 2018)1 is that media of various kinds play an increasingly important role in shaping people’s knowledge, desires, practices and expectations about intimate relationships. While arguments rage about the nature and content of sex and relationship education in schools, it is becoming clear that more and more of us – young and old – look not to formal education, or even to our friends, for information about sex, but to the media (Albury, 2016; Attwood et al., 2015). This is not simply a matter of media ‘advice’ in the form of self-help books, magazine problem pages, or online ‘agony’ columns – though these are all proliferating and are discussed at length in the book. It is also about the wider cultural habitat of images, ideas and discourses about intimacy that circulate through and across media: the ‘happy endings’ of romantic comedies; the ‘money shots’ of pornography; the celebrity gossip about who is seeing whom, who is ‘cheating’, and who is looking ‘hot’; the lifestyle TV about ‘embarrassing bodies’ or being ‘undateable’; the newspaper features on how to have a ‘good’ divorce or ‘ten things never to say on a first date’; the new apps that incite us to quantify and rate our sex lives, and so forth. These constitute the ‘taken for granted’ of everyday understandings of intimacy, and they are at the heart of Mediated Intimacy
Precursor ion scanning for detection and structural characterization of heterogeneous glycopeptide mixtures
AbstractThe structure of N-linked glycans is determined by a complex, anabolic, intracellular pathway but the exact role of individual glycans is not always clear. Characterization of carbohydrates attached to glycoproteins is essential to aid understanding of this complex area of biology. Specific mass spectral detection of glycopeptides from protein digests may be achieved by on-line HPLC-MS, with selected ion monitoring (SIM) for diagnostic product ions generated by cone voltage fragmentation, or by precursor ion scanning for terminal saccharide product ions, which can yield the same information more rapidly. When glycosylation is heterogeneous, however, these approaches can result in spectra that are complex and poorly resolved. We have developed methodology, based around precursor ion scanning for ions of high m/z, that allows site specific detection and structural characterization of glycans at high sensitivity and resolution. These methods have been developed using the standard glycoprotein, fetuin, and subsequently applied to the analysis of the N-linked glycans attached to the scrapie-associated prion protein, PrPSc. These glycans are highly heterogeneous and over 30 structures have been identified and characterized site specifically. Product ion spectra have been obtained on many glycopeptides confirming structure assignments. The glycans are highly fucosylated and carry Lewis X or sialyl Lewis X epitopes and the structures are in-line with previous results. [Abbreviations: Hex–Hexose, C6H12O6 carbohydrates, including mannnose and galactose; HexNAc—N-acetylhexosamine, C8H15NO6 carbohydrates, including N-acetylglucosamine and N-acetylgalactosamine; GlcNAc—N-acetylglucosamine; GalNAc—N-acetylgalactosamine; Fuc–Fucose; NeuAC—N-acetylneuraminic acid or sialic acid; TSE—Transmissible Spongiform Encephalopathy.
Correlation energy of two electrons in the high-density limit
We consider the high-density-limit correlation energy \Ec in
dimensions for the ground states of three two-electron systems: helium
(in which the electrons move in a Coulombic field), spherium (in which they
move on the surface of a sphere), and hookium (in which they move in a
quadratic potential). We find that the \Ec values are strikingly similar,
depending strongly on but only weakly on the external potential. We
conjecture that, for large , the limiting correlation energy \Ec \sim
-\delta^2/8 in any confining external potential, where .Comment: 4 pages, 0 figur
Chemistry in One Dimension
We report benchmark results for one-dimensional (1D) atomic and molecular
systems interacting via the Coulomb operator . Using various
wavefunction-type approaches, such as Hartree-Fock theory, second- and
third-order M{\o}ller-Plesset perturbation theory and explicitly correlated
calculations, we study the ground state of atoms with up to ten electrons as
well as small diatomic and triatomic molecules containing up to two electrons.
A detailed analysis of the 1D helium-like ions is given and the expression of
the high-density correlation energy is reported. We report the total energies,
ionization energies, electron affinities and other interesting properties of
the many-electron 1D atoms and, based on these results, we construct the 1D
analog of Mendeleev's periodic table. We find that the 1D periodic table
contains only two groups: the alkali metals and the noble gases. We also
calculate the dissociation curves of various 1D diatomics and study the
chemical bond in H, HeH, He, H, HeH and
He. We find that, unlike their 3D counterparts, 1D molecules are
primarily bound by one-electron bonds. Finally, we study the chemistry of
H and we discuss the stability of the 1D polymer resulting from an
infinite chain of hydrogen atoms.Comment: 27 pages, 7 figure
A new code for parameter estimation in searches for gravitational waves from known pulsars
We describe the consistency testing of a new code for gravitational wave
signal parameter estimation in known pulsar searches. The code uses an
implementation of nested sampling to explore the likelihood volume. Using fake
signals and simulated noise we compare this to a previous code that calculated
the signal parameter posterior distributions on both a grid and using a crude
Markov chain Monte Carlo (MCMC) method. We define a new parameterisation of two
orientation angles of neutron stars used in the signal model (the initial phase
and polarisation angle), which breaks a degeneracy between them and allows more
efficient exploration of those parameters. Finally, we briefly describe
potential areas for further study and the uses of this code in the future.Comment: Accepted for proceedings of Amaldi 9 meetin
Uniform Electron Gases. II. The Generalized Local Density Approximation in One Dimension
We introduce a generalization (gLDA) of the traditional Local Density
Approximation (LDA) within density functional theory. The gLDA uses both the
one-electron Seitz radius \rs and a two-electron hole curvature parameter
at each point in space. The gLDA reduces to the LDA when applied to the
infinite homogeneous electron gas but, unlike the LDA, is is also exact for
finite uniform electron gases on spheres. We present an explicit gLDA
functional for the correlation energy of electrons that are confined to a
one-dimensional space and compare its accuracy with LDA, second- and
third-order M{\o}ller-Plesset perturbation energies and exact calculations for
a variety of inhomogeneous systems.Comment: 26 pages, 2 figures, accepted for publication in Journal of Chemical
Physic
Is the transition redshift a new cosmological number?
Observations from Supernovae Type Ia (SNe Ia) provided strong evidence for an
expanding accelerating Universe at intermediate redshifts. This means that the
Universe underwent a transition from deceleration to acceleration phases at a
transition redshift of the order unity whose value in principle depends
on the cosmology as well as on the assumed gravitational theory. Since
cosmological accelerating models endowed with a transition redshift are
extremely degenerated, in principle, it is interesting to know whether the
value of itself can be observationally used as a new cosmic
discriminator. After a brief discussion of the potential dynamic role played by
the transition redshift, it is argued that future observations combining SNe
Ia, the line-of-sight (or "radial") baryon acoustic oscillations, the
differential age of galaxies, as well as the redshift drift of the spectral
lines may tightly constrain , thereby helping to narrow the parameter
space for the most realistic models describing the accelerating Universe.Comment: 12 pages, 5 figures. Some discussions about how to estimate the
transition redshift have been added. New data by Planck and H(z) data have
been mentioned. New references have been adde
Technology evaluation of heating, ventilation, and air conditioning for MIUS application
Potential ways of providing heating, ventilation, and air conditioning for a building complex serviced by a modular integrated utility system (MIUS) are examined. Literature surveys were conducted to investigate both conventional and unusual systems to serve this purpose. The advantages and disadvantages of the systems most compatible with MIUS are discussed
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