La importación de productos plásticos a la Argentina

Desde el mes de febrero del año 2012, las importaciones argentinas se han visto afectadas por un nuevo régimen plasmado en la Resolución N° 3255-12 AFIP la cual establece la presentación de una declaración jurada anticipada de importación (DJAI), documento único y de uso común, que implica cumplir con ciertos requisitos a la hora de ingresar productos (entre ellos productos plásticos) a la Argentina, constituyendo un verdadero obstáculo para las empresas nacionales. En 2013 este sistema de trabas a las importaciones sigue mostrando tantas desprolijidades como en el inicio de su aplicación. La única norma existente es la declaración jurada que constituye el marco del sistema, pero el resto de su reglamentación se maneja de manera informal, es decir, verbalmente, por parte de la Secretaria de Comercio ya sea mediante consultas telefónicas o personalmente. Luego de casi dos años de funcionamiento del mencionado régimen, hemos podido visualizar el impacto negativo que ha generado en importadores/distribuidores que han visto decaer sus operaciones, en empresas que han tenido que invertir recursos en buscar alternativas para sustituir importaciones con altos costos económicos y de tiempo, en industrias locales en las que se ha producido un notable desabastecimiento de insumos necesarios para proveer al mercado local y que cumpliendo las exigencias de Gobierno intentan exportar lo que fabrican, en mayoristas internacionales que han tenido que retirarse del país además de realización de cierres de sucursales y pérdidas de puestos de trabajo. En por ello que el objetivo principal de nuestro trabajo es el desarrollo del régimen de Declaraciones Juradas Anticipadas de Importaciones para el desenvolvimiento de Pequeñas y Medianas Empresas argentinas vinculadas al sector del plástico ( fabricación, importaciones, exportaciones) y también a aquellas personas interesadas en tomar conocimientos de este régimen impuesto por el Gobierno Nacional.Fil: Blanco, Vanesa Giselle. Universidad Nacional de Cuyo. Facultad de Ciencias Económicas.Fil: Gil, Germán Ricardo. Universidad Nacional de Cuyo. Facultad de Ciencias Económicas.Fil: Fayad, Mariana. Universidad Nacional de Cuyo. Facultad de Ciencias Económicas

Healthcare workers hospitalized due to COVID-19 have no higher risk of death than general population. Data from the Spanish SEMI-COVID-19 Registry

Aim To determine whether healthcare workers (HCW) hospitalized in Spain due to COVID-19 have a worse prognosis than non-healthcare workers (NHCW). Methods Observational cohort study based on the SEMI-COVID-19 Registry, a nationwide registry that collects sociodemographic, clinical, laboratory, and treatment data on patients hospitalised with COVID-19 in Spain. Patients aged 20-65 years were selected. A multivariate logistic regression model was performed to identify factors associated with mortality. Results As of 22 May 2020, 4393 patients were included, of whom 419 (9.5%) were HCW. Median (interquartile range) age of HCW was 52 (15) years and 62.4% were women. Prevalence of comorbidities and severe radiological findings upon admission were less frequent in HCW. There were no difference in need of respiratory support and admission to intensive care unit, but occurrence of sepsis and in-hospital mortality was lower in HCW (1.7% vs. 3.9%; p = 0.024 and 0.7% vs. 4.8%; p<0.001 respectively). Age, male sex and comorbidity, were independently associated with higher in-hospital mortality and healthcare working with lower mortality (OR 0.211, 95%CI 0.067-0.667, p = 0.008). 30-days survival was higher in HCW (0.968 vs. 0.851 p<0.001). Conclusions Hospitalized COVID-19 HCW had fewer comorbidities and a better prognosis than NHCW. Our results suggest that professional exposure to COVID-19 in HCW does not carry more clinical severity nor mortality

Clonal chromosomal mosaicism and loss of chromosome Y in elderly men increase vulnerability for SARS-CoV-2

The pandemic caused by severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2, COVID-19) had an estimated overall case fatality ratio of 1.38% (pre-vaccination), being 53% higher in males and increasing exponentially with age. Among 9578 individuals diagnosed with COVID-19 in the SCOURGE study, we found 133 cases (1.42%) with detectable clonal mosaicism for chromosome alterations (mCA) and 226 males (5.08%) with acquired loss of chromosome Y (LOY). Individuals with clonal mosaic events (mCA and/or LOY) showed a 54% increase in the risk of COVID-19 lethality. LOY is associated with transcriptomic biomarkers of immune dysfunction, pro-coagulation activity and cardiovascular risk. Interferon-induced genes involved in the initial immune response to SARS-CoV-2 are also down-regulated in LOY. Thus, mCA and LOY underlie at least part of the sex-biased severity and mortality of COVID-19 in aging patients. Given its potential therapeutic and prognostic relevance, evaluation of clonal mosaicism should be implemented as biomarker of COVID-19 severity in elderly people. Among 9578 individuals diagnosed with COVID-19 in the SCOURGE study, individuals with clonal mosaic events (clonal mosaicism for chromosome alterations and/or loss of chromosome Y) showed an increased risk of COVID-19 lethality

Gestión del conocimiento: perspectiva multidisciplinaria. Volumen 11

El libro “Gestión del Conocimiento. Perspectiva Multidisciplinaria”, Volumen 11, de la Colección Unión Global, es resultado de investigaciones. Los capítulos del libro, son resultados de investigaciones desarrolladas por sus autores. El libro cuenta con el apoyo de los grupos de investigación: Universidad Sur del Lago “Jesús María Semprúm” (UNESUR), Zulia – Venezuela; Universidad Politécnica Territorial de Falcón Alonso Gamero (UPTAG), Falcón – Venezuela; Universidad Politécnica Territorial de Mérida Kleber Ramírez (UPTM), Mérida – Venezuela; Universidad Guanajuato (UG) - Campus Celaya - Salvatierra - Cuerpo Académico de Biodesarrollo y Bioeconomía en las Organizaciones y Políticas Públicas (C.A.B.B.O.P.P), Guanajuato – México; Centro de Altos Estudios de Venezuela (CEALEVE), Zulia – Venezuela, Centro Integral de Formación Educativa Especializada del Sur (CIFE - SUR) - Zulia - Venezuela, Centro de Investigaciones Internacionales SAS (CIN), Antioquia - Colombia.y diferentes grupos de investigación del ámbito nacional e internacional que hoy se unen para estrechar vínculos investigativos, para que sus aportes científicos formen parte de los libros que se publiquen en formatos digital e impreso

Low cost middle infrared sensor for the characterization of alcohol and gasoline blends

This study is focuses on the use of a MID Infrared low cost and uncooled sensor in gasolines, improved to classify and quantify blends with ethanol, methanol and butanol in percentages that range from 10 to 30 % of alcohol (most frequently used for blending or adulteration). This application is a prospective for detecting adulteration qualitatively and also to quantify that the additive ratio

Virtual MWIR spectra for improved quantification of fuel mixtures

Previous research of the authors has demonstrated that uncooled low-cost MWIR Spectroscopy is a fast and non-invasive method for the qualitative and quantitative evaluation of fuels and their blending with alcohols: methanol, ethanol and propanol among others. However impressive, the preliminary tests have failed to reach the minimum required accuracy + 1%. A main difficulty, in order to reach the expected estimation performance, lays on the generation of very narrow volume of mixture, of ever decreasing additive concentration. This paper proposes a new chemometric procedure, as an in-silico experimental procedure that would help the generation of stable virtual spectra of ultra-low additive concentration. To do so, a previous MANOVA model is used to generate noiseless points in the canonical plane of binary mixtures of fuel and alcohols. Afterwards the Cartesian coordinates of each mixture are de-projected into the estimated original spectra, which shall be onwards called virtual. The so called virtual spectra are then fed into a PLS model for the identification of the additive and corresponding estimation of the concentration, which is validated with regard to the experimental samples

Fatty Acid Binding Proteins 3 and 4 Predict Both All-Cause and Cardiovascular Mortality in Subjects with Chronic Heart Failure and Type 2 Diabetes Mellitus

Subjects with type 2 diabetes mellitus (T2D) are at increased risk for heart failure (HF). The cardiac-specific (FABP3) and adipose-tissue-specific (FABP4) types of the fatty acid binding proteins have been associated with both all-cause and cardiovascular (CV) mortality. The aim of this study was to explore the prognosis value of FABP3 and FABP4 in ambulatory subjects with chronic HF (CHF), with and without T2D. A prospective study involving 240 ambulatory CHF subjects was performed. Patients were followed-up for a mean of 5.78 ± 3.30 years and cause of death (if any) was recorded. Primary endpoints were defined as all-cause and CV death, and a composite endpoint that included CV death or hospitalization for HF was included as a secondary endpoint. Baseline serum samples were obtained and the serum FABP3 and FABP4 concentrations were assessed by sandwich enzyme-linked immunosorbent assay. Survival analysis was performed with multivariable Cox regressions, using Fine and Gray competing risks models when needed, to explore the prognostic value of FABP3 and FABP4 concentrations, adjusting for potential confounders. Type 2 diabetes mellitus was highly prevalent, accounting for 47.5% for total subjects with CHF. Subjects with T2D showed higher mortality rates (T2D: 69.30%; non-T2D: 50.79%, p = 0.004) and higher serum FABP3 (1829.3 (1104.9-3440.5) pg/mL vs. 1396.05 (820.3-2362.16) pg/mL, p = 0.007) and FABP4 (45.5 (27.6-79.8) ng/mL vs. 34.1 (24.09-55.3) ng/mL, p = 0.006) concentrations compared with non-T2D CHF subjects. In the whole study cohort, FABP3 was independently associated with all-cause death, and both FABP3 and FABP4 concentrations were associated with CV mortality. The predictive values of these two molecules for all-cause (FABP3: HR 1.25, 95% CI 1.09-1.44; p = 0.002. FABP4: HR 2.21, 95% CI 1.12-4.36; p = 0.023) and CV mortality (FABP3: HR 1.28, 95% CI 1.09-1.50; p = 0.002. FABP4: HR 4.19, 95% CI 2.21-7.95; p < 0.001) were only statistically significant in the subgroup of subjects with T2D. Notably, FABP4 (HR 2.07, 95% CI 1.11-3.87; p = 0.022), but not FABP3, also predicted the occurrence of the composite endpoint (death or hospitalization for HF) only in subjects with T2D. All these associations were not found in CHF subjects without T2D. Our findings support the usefulness of serum FABP3 and FABP4 concentrations as independent predictors for the occurrence of all-cause and CV mortality in ambulatory subjects with CHF with T2D

Laboratorio de creación poética: un espacio colaborativo de escritura en la universidad

Este proyecto de innovación docente consiste en la creación de un Laboratorio poético: un espacio colaborativo de escritura de poesía dirigido a estudiantes de distintos grados y másteres de Filología de la Universidad Complutense de Madrid. Se ha llevado a cabo un trabajo colectivo de taller, y este se ha acompañado de seminarios de formación práctica, encuentros con poetas y otras actividades de creación, en cuya organización han intervenido los propios estudiantes, como recitales y publicaciones.Depto. de Lengua Española y Teoría de la LiteraturaFac. de FilologíaFALSEsubmitte