Resource partitioning revisited: evidence from Italian television broadcasting

The theory of resource partitioning proposes that competition among generalists in the center of a market can trigger a process of resource release that engenders a proliferation of specialist producers outside the center. Previous research has generally examined the relationship between this proliferation and market concentration—a correlate of competitive intensity in the center of the market. In this paper, we extend the theory by arguing that resource release also occurs as the degree of competitive overlap among producers in the center intensifies, even when concentration or other structural features do not vary; we expand its implications by demonstrating that increased competitive overlap in the market center can enhance the viability of producers positioned near the center more than those in the periphery; and we enrich and complete it by specifying the additional assumptions needed to extend the theory of resource partitioning to entry processes. Consistent with our expectations, an empirical examination of the Italian broadcast television industry, from 1992 to 2003, finds that the failure rates of both near-center and peripheral stations decline with greater competitive overlap in the programming of the national broadcasters, with the failure rates of the near-center stations falling more than those of peripheral stations. Greater competitive overlap similarly stimulates the entry of near-center stations more than peripheral one

Numerical modelling of the behavior os ties under tension in brick veneer walls

Com o objetivo de avaliar o comportamento da ligação de paredes de tijolo face à vista a paredes de alvenaria de enchimento, foi definida uma campanha de ensaios para a caracterização do comportamento de diferentes tipos de ligadores sujeitos a diferentes configurações de carga (ações monotónicas e cíclicas de tração). Adicionalmente, com o objetivo de compreender em detalhe os fatores que afetam o comportamento da ligação parede de tijolo face à vista e parede de tijolo de enchimento através de ligadores metálicos, procedeu-se à calibração de um modelo numérico com base nos resultados experimentais obtidos nos ensaios de tração. Neste trabalho pretende-se apresentar os resultados da calibração do modelo numérico e de uma análise paramétrica para avaliação dos parâmetros mecânicos que mais influenciam o comportamento da ligação a ações de tração.Aiming at assessing the mechanical behavior of the connection of brick veneer walls to the backing system (brick infill walls), an experimental campaign was defined for the experimental characterization of the behavior of distinct types of ties subjected to distinct loading configurations, namely monotonic and cyclic tension and compression loading. Additionally, with the goal of completing the experimental results and achieve a better insight on the main parameters influencing the connection, a numerical model was built and validated based on monotonic tension experimental tests. In this work, it is intended to show the results of the numerical model calibration and analyze the results of a sensitivity analyses on the influence of the mechanical properties on the tensile behavior of the tie

Generation of ultrashort pulses by four wave mixing in a gas-filled hollow core fiber

The four wave mixing (FWM) process is widely exploited for the generation of tunable ultrashort light pulses. Usually this process is driven in bulk materials, which are however prone to optical damage at high pump laser intensities. A tunable source of ultrashort 10 mu J level pulses in the visible spectral region is described here. In particular, we report on the implementation of FWM driven by a two-color ultrafast laser pulse inside a gas-filled hollow core fiber (HCF). Due to the high-damage threshold and the long interaction distance, the HCF-based FWM configuration proves to be suitable for high-energy applications. Moreover, this technique can be potentially used for ultrashort pulses generation within a wide range of spectral regions; a discussion on the possibility to extend our scheme to the generation of few-cycle mid-IR pulse is provided

The 2020 Italian Society of Arterial Hypertension (SIIA) practical guidelines for the management of primary aldosteronism

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SARS-CoV-2 Breakthrough Infections: Incidence and Risk Factors in a Large European Multicentric Cohort of Health Workers

The research aimed to investigate the incidence of SARS-CoV-2 breakthrough infections and their determinants in a large European cohort of more than 60,000 health workers

Antidiabetic Drug Prescription Pattern in Hospitalized Older Patients with Diabetes

Objective: To describe the prescription pattern of antidiabetic and cardiovascular drugs in a cohort of hospitalized older patients with diabetes. Methods: Patients with diabetes aged 65 years or older hospitalized in internal medicine and/or geriatric wards throughout Italy and enrolled in the REPOSI (REgistro POliterapuie SIMI—Società Italiana di Medicina Interna) registry from 2010 to 2019 and discharged alive were included. Results: Among 1703 patients with diabetes, 1433 (84.2%) were on treatment with at least one antidiabetic drug at hospital admission, mainly prescribed as monotherapy with insulin (28.3%) or metformin (19.2%). The proportion of treated patients decreased at discharge (N = 1309, 76.9%), with a significant reduction over time. Among those prescribed, the proportion of those with insulin alone increased over time (p = 0.0066), while the proportion of those prescribed sulfonylureas decreased (p < 0.0001). Among patients receiving antidiabetic therapy at discharge, 1063 (81.2%) were also prescribed cardiovascular drugs, mainly with an antihypertensive drug alone or in combination (N = 777, 73.1%). Conclusion: The management of older patients with diabetes in a hospital setting is often sub-optimal, as shown by the increasing trend in insulin at discharge, even if an overall improvement has been highlighted by the prevalent decrease in sulfonylureas prescription

The “Diabetes Comorbidome”: A Different Way for Health Professionals to Approach the Comorbidity Burden of Diabetes

(1) Background: The disease burden related to diabetes is increasing greatly, particularly in older subjects. A more comprehensive approach towards the assessment and management of diabetes’ comorbidities is necessary. The aim of this study was to implement our previous data identifying and representing the prevalence of the comorbidities, their association with mortality, and the strength of their relationship in hospitalized elderly patients with diabetes, developing, at the same time, a new graphic representation model of the comorbidome called “Diabetes Comorbidome”. (2) Methods: Data were collected from the RePoSi register. Comorbidities, socio-demographic data, severity and comorbidity indexes (Cumulative Illness rating Scale CIRS-SI and CIRS-CI), and functional status (Barthel Index), were recorded. Mortality rates were assessed in hospital and 3 and 12 months after discharge. (3) Results: Of the 4714 hospitalized elderly patients, 1378 had diabetes. The comorbidities distribution showed that arterial hypertension (57.1%), ischemic heart disease (31.4%), chronic renal failure (28.8%), atrial fibrillation (25.6%), and COPD (22.7%), were the more frequent in subjects with diabetes. The graphic comorbidome showed that the strongest predictors of death at in hospital and at the 3-month follow-up were dementia and cancer. At the 1-year follow-up, cancer was the first comorbidity independently associated with mortality. (4) Conclusions: The “Diabetes Comorbidome” represents the perfect instrument for determining the prevalence of comorbidities and the strength of their relationship with risk of death, as well as the need for an effective treatment for improving clinical outcomes

Polarized blazar X-rays imply particle acceleration in shocks

Most of the light from blazars, active galactic nuclei with jets of magnetized plasma that point nearly along the line of sight, is produced by high-energy particles, up to around 1 TeV. Although the jets are known to be ultimately powered by a supermassive black hole, how the particles are accelerated to such high energies has been an unanswered question. The process must be related to the magnetic field, which can be probed by observations of the polarization of light from the jets. Measurements of the radio to optical polarization—the only range available until now—probe extended regions of the jet containing particles that left the acceleration site days to years earlier1,2,3, and hence do not directly explore the acceleration mechanism, as could X-ray measurements. Here we report the detection of X-ray polarization from the blazar Markarian 501 (Mrk 501). We measure an X-ray linear polarization degree ΠX of around 10%, which is a factor of around 2 higher than the value at optical wavelengths, with a polarization angle parallel to the radio jet. This points to a shock front as the source of particle acceleration and also implies that the plasma becomes increasingly turbulent with distance from the shock