710 research outputs found
Prospects for the prevention of free radical disease, regarding cancer and cardiovascular disease
Free radicals may be involved in the aetiology of cancer and cardiovascular diseases. In epidemiological studies poor plasma levels of all essential antioxidants are associated with increased relative risks; in particular, low levels of carotene and vitamin E with the risk of cancer and ischemic heart disease, respectively. The studies suggest that for optimal synergistic protection the plasma antioxidant levels should simultaneously exceed the threshold values of 28-30 μmol/l lipid-standardized vitamin E, 40-50 μmol/l vitamin C, 0.4-0.5 (μmol/l carotene and 2.2-2.8 μmol/l lipid-standardized vitamin A. However the preventive efficacy of an optional antioxidant status is still to be proven in randomized intervention trials. Although these antioxidant micronutrients may be the primary protective components of vegetable-rich ‘preventive' diets, the potentials of other plant components await exploration, eg carotenoids other than β-carotene, bioflavonoids and oxygen-sensitive B-vitamin
An evaluation resource for geographic information retrieval
In this paper we present an evaluation resource for geographic information retrieval developed within the Cross Language Evaluation
Forum (CLEF). The GeoCLEF track is dedicated to the evaluation of geographic information retrieval systems. The resource
encompasses more than 600,000 documents, 75 topics so far, and more than 100,000 relevance judgments for these topics. Geographic
information retrieval requires an evaluation resource which represents realistic information needs and which is geographically
challenging. Some experimental results and analysis are reported
GeoCLEF 2007: the CLEF 2007 cross-language geographic information retrieval track overview
GeoCLEF ran as a regular track for the second time within the Cross
Language Evaluation Forum (CLEF) 2007. The purpose of GeoCLEF is to test
and evaluate cross-language geographic information retrieval (GIR): retrieval
for topics with a geographic specification. GeoCLEF 2007 consisted of two sub
tasks. A search task ran for the third time and a query classification task was
organized for the first. For the GeoCLEF 2007 search task, twenty-five search
topics were defined by the organizing groups for searching English, German,
Portuguese and Spanish document collections. All topics were translated into
English, Indonesian, Portuguese, Spanish and German. Several topics in 2007
were geographically challenging. Thirteen groups submitted 108 runs. The
groups used a variety of approaches. For the classification task, a query log
from a search engine was provided and the groups needed to identify the
queries with a geographic scope and the geographic components within the
local queries
Challenges to evaluation of multilingual geographic information retrieval in GeoCLEF
This is the third year of the evaluation of
geographic information retrieval (GeoCLEF)
within the Cross-Language Evaluation Forum
(CLEF). GeoCLEF 2006 presented topics and
documents in four languages (English,
German, Portuguese and Spanish). After two
years of evaluation we are beginning to
understand the challenges to both Geographic
Information Retrieval from text and of
evaluation of the results of geographic
information retrieval. This poster enumerates
some of these challenges to evaluation and
comments on the limitations encountered in the
first two evaluations
GeoCLEF 2006: the CLEF 2006 Ccross-language geographic information retrieval track overview
After being a pilot track in 2005, GeoCLEF advanced to be a regular track within CLEF 2006. The
purpose of GeoCLEF is to test and evaluate cross-language geographic information retrieval (GIR): retrieval for
topics with a geographic specification. For GeoCLEF 2006, twenty-five search topics were defined by the
organizing groups for searching English, German, Portuguese and Spanish document collections. Topics were
translated into English, German, Portuguese, Spanish and Japanese. Several topics in 2006 were significantly
more geographically challenging than in 2005. Seventeen groups submitted 149 runs (up from eleven groups and
117 runs in GeoCLEF 2005). The groups used a variety of approaches, including geographic bounding boxes,
named entity extraction and external knowledge bases (geographic thesauri and ontologies and gazetteers)
Enhanced protein synthesis and secretion using a rational signal-peptide library approach as a tailored tool
publishedVersio
Enhanced protein synthesis and secretion using a rational signal-peptide library approach as a tailored tool
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