Public-private partnership in the Russian educational system

The article grounds the need for private-public partnership development in the Russian educational system. Authors highlighted the issues of state, educational, and business institutions’ interaction considering the best foreign experience. Authors suggest more attention to the funding of innovational infrastructure of universities in the context of public-private partnership providing economic stability and increase in budget revenues as well as in social expenditures.peer-reviewe

Feasibility Study for a Neutron-Based Investigation of Polymer Cement Concretes

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Dynamics of energetic spectrum of solar-diurnal variations of cosmic rays in 19-24 solar activity cycles

The anisotropic angular distribution of cosmic rays (CR) in the interplanetary medium manifests itself on Earth as periodic diurnal intensity variations. Ground-based detectors of CRs have different energy sensitivity to the primary CR radiation and, therefore, the amplitude and phase recorded by them are also different. This fact makes it possible to study the energy spectrum of the variations when using a sufficient number of detectors. In this work, the results of the investigation of the energy spectrum of solar-diurnal variations of CRs obtained by a network of neutron monitors and muon telescopes are presented. The network allows measuring CRs with median energies from units to hundreds of GeV. The expected values of the amplitude and phase of the daily CR variations at the selected ground-based stations for different types of the energy spectrum are shown. The calculated data are compared with experimental data for 19-24 solar activity cycles

Nanoscale investigation of polymer cement concretes by small angle neutron scattering

An analysis of dense cements, such as polymer cement concrete, is made to produce original innovative components for different types of constructing materials. These materials present good functional properties (ageing resistance, crack formation resistance, hardness, and stability of mechanical modules) and can be used for various applications. In this paper, experimental tests on Portland cement with added γ-Al 2 O 3 and redispersible dry polymer performed using small angle neutron scattering are reported. The objective of the investigation was to assess the key parameters of the material (e.g., porosity, fractal dimensions, and size distribution) at the nanoscale level as well as to obtain useful structural information for expanding the possibility of applications. The results obtained can contribute to the optimisation of the consistency of the material, the design of operating conditions of elements of structures and facilities, and the design of the procedures that support ecological criteria and enhance quality and safety levels. © 2017 Walter de Gruyter GmbH, Berlin/Boston

COVID-19 and Other Challenges: A Case Study of Certified Organic Green Tea Producers in China

Funder: Renmin University of China; FundRef: https://doi.org/10.13039/501100004260 This article explores how the western concept of “organic agriculture” has been applied in the traditional Chinese tea industry and how it has been tested during the COVID-19 pandemic. Using in-depth interviews and observations made during 2017–2020, we analyzed different meanings of organic agriculture and values that were given by Chinese farmers who are certified organic producers. Although organic agriculture, particular certified by international certification standards, is a foreign concept, producers invested efforts that go beyond the commercial pursuit for profit. Most importantly, the combination of the reiterated cultural meaning and health benefits of the certified organic tea with the visionary strategy has allowed these producers to shift in a timely manner from export to domestic markets and adapt to the pandemic’s barriers presented to the global trade. </jats:p

Cosmic ray angular distribution dynamics during Forbush decrease in 3-4 November 2021

On November 3-4, 2021, there was a coronal ejection of the solar mass into the interplanetary medium. According to direct observations of the interplanetary magnetic field and the solar wind, the ejection was accompanied by a magnetic cloud. During the event, neutron monitors of the NMDB network registered a two-stage Forbush decrease with a total amplitude of up to 15%. A preliminary analysis of the NMDB data shows that the first step was due to the cosmic ray decrease behind the shock wave front, while the second step was due to the cosmic ray anisotropy formed in the magnetic cloud. This work was undertaken to study the dynamics of the angular distribution of cosmic rays in this event. The cosmic ray distribution was determined using the global survey method developed at the ShICRA in the 1960s. The method makes it possible to use the worldwide network of neutron monitors as a single multidirectional instrument and to determine the hourly dynamics of CR distribution. It is shown that unidirectional and bidirectional anisotropies of significant amplitude are observed inside the magnetic cloud. The results obtained are discussed in the framework of modern theories of the formation of magnetic clouds. The temporal dynamics of the spatial-angular distribution of cosmic rays during the Forbush decrease on November 3–4, 2021 was determined. The presence of cosmic ray anisotropy with an amplitude comparable to the magnitude of the density decrease itself was found

THE BIOSYNTHESIS REGULATION OF POTATO STEROIDAL GLYCOALKALOIDS

Potato steroidal glycoalkaloids (SGAs) compose a part of plant immunity. Some of their modified variants are toxic to humans. In the course of potato domestication, plants with a lower SGA level were selected. The advent of approaches for manipulation with the regulation of metabolic pathways provides an opportunity to overcome the undesirable direct relationship between the potato resistance to pests and the toxicity of its tubers. However, for such a fine regulation, a deep knowledge of the regulatory network of potato SGA biosynthesis is required. The purpose of this review is to summarize the information on the known SGA biosynthesis genes in plants and the results of the investigation of these genes in potato, as well as to consider the mechanisms of the SGA protective toxic action against pathogens and pests. The SGA biosynthesis is realized via the cytosolic mevalonate pathway and consists of three stages. The first two stages are required for the synthesis of primary metabolites, and lead to cycloartanol and cholesterol, respectively. Twelve enzymes are involved in the biosynthesis, and the half of them are involved in the biosynthesis of phytosterols, which is a branch of the first stage of this metabolic pathway. In the potato leaves with an excess of phytosterols, the synthesis switches to SGAs, increasing the content of the latter. In tubers, with an excess of SGA precursors, they are involved in the synthesis of lanosterol, supporting in this way the stable level of SGA. The importance of structural genes encoding the enzymes of the first two stages of biosynthesis does not allow us to consider them as a target for knockout in order to reduce the level of SGAs. However, information about the tissue-specific mechanisms of switching between the pathways of synthesis of SGA and other compounds having common precursors with SGAs can be used to manipulate the tissue-specific level of steroidal glycoalkaloids. At the third stage (the synthesis of glycoalkaloids from cholesterol), about 20 enzymes participate. In the potato genome, 14 corresponding genes were identified, 8 of which were studied in detail using reverse genetics approaches. As a promising target for reducing SGA levels in tubers, the genes encoding PGA enzymes (belonging to the CYP72 subfamily cytochrome-P450-dependent monooxygenases catalyzing the conversion of hydrocholesterol to trihydrocholesterol) and SGT (SGA glycosyltransferases that catalyze the conversion of solanidine to its toxic glycosylated derivatives α-solanine and α-chaconine) are considered. Cis-regulatory elements in the promoter regions of some glycoalkaloid biosynthesis genes, including elements responsible for tissue-specific expression, are described. The accumulated information provides the base for creating potato genotypes with tissue-specific regulation of SGAs, in which high levels of SGAs in leaves will remain to protect against pathogens and pests and, at the same time, the synthesis of toxic substances in tubers will be suppresse

Current achievements in modifying crop genes using CRISPR/Cas system

With the advent of the new genome editing tool of target-specifically customizable endonucleases, a huge variety of novel opportunities have become feasible. The crop improvement is one of the main applications of genome editing in plant science and plant biotechnology. The amount of publications referring to genome editing and CRISPR/Cas system based molecular tools application in crops is permanently growing. The aim of this study is the systematization and cataloging of these data. Earlier we published the first catalog of targeted crop genome modifications as of February 10, 2017. The current review is an update of the catalog; it covers research papers on crop genome modifications from February 10, 2017 to August 17, 2018, found by searching 47 crop names in the Scopus database. Over one year and a half, 377 articles mentioning CRISPR/Cas and crop names have been published, of which 131 articles describe an experimental application of this tool for editing 193 genes in 19 crops, including rice with the largest number of genes modified (109 genes). Editing 50 of 193 genes was aimed at crop improvement. The catalog presented here includes these 50 genes, specifying the cultivars, each gene and gene product function, modification type and delivery method used. The current full list of genes modified with CRISPR/Cas with the aim of crop improvement is 81 in 16 crops (for 5 years from August 2013 to August 2018). In this paper, we also summarize data on different modifications types in different crops and provide a brief review of some novel methods and approaches that have appeared in crop genome editing research over the reviewed period. Taken together, these data provide a clear view on current progress in crop genome modifications and traits improvement using CRISPR/Cas based genome editing technology

Budgetary instruments of public finance management

In the context of global changes, Russia faces the challenges of not only countering the economic sanctions of the West, but also fulfilling its obligations to implement the Sustainable Development Goals, legislated in 2018. The purpose of the study is to critically examine the content of budget instruments, and their role in modern conditions, problems of functioning and areas of improvement. The key instrument of state financial policy is the federal budget, the resource capabilities of which make it possible to finance national projects, measures to implement the Messages of the President of the Russian Federation, 42 government initiatives. The conclusions are based on the analysis of open data of the Ministry of Finance of the Russian Federation. The study substantiates the need to transform the institute of state programs and related tax expenditures and budget expenditure reviews. It is revealed that they provide objective evidence of managerial decision-making in the field of public finance. Their further improvement is connected with the expansion of the tax independence of the sub-federal government, as well as the consolidation in the budget legislation of provisions on the formation of tax expenditures and conducting reviews of budget expenditures. The results of the study can be used by legislative and executive authorities in developing proposals for improving budget legislation, the implementation of which will contribute to the selection of relevant areas of financing, effective use of budget funds, and increased transparency of budget information