938 research outputs found
Multinational Comparisons of Health Systems Data, 2008
Updates international comparison graphs and charts of 2008 health data among OECD countries, including healthcare spending by source and service, length of hospital stay, supply of physicians and nurses, drug coverage, medical technology, and mortality
Multinational Comparisons of Health Systems Data, 2009
Provides charts and graphs of international comparisons of health data among OECD countries, including spending on health care, length of hospital stay, number of physician visits, drug prices, prevalence of smoking and of obesity, and life expectancy
Influence of Di erent Sieving Methods on Estimation of Sand Size Parameters
Sieving is one of the most used operational methods to determine sand size parameters
which are essential to analyze coastal dynamics. However, the influence of hand versus mechanical
shaking methods has not yet been studied. Herein, samples were taken from inside the hopper of
a trailing suction dredger and sieved by hand with sieves of 10 and 20 cm diameters on board the
dredger. Afterwards, these same samples were sieved with a mechanical shaker in the laboratory on
land. The results showed di erences for the main size parameters D50, standard deviation, skewness,
and kurtosis. Amongst the main results, it should be noted that the highest values for D50 and
kurtosis were given by the small sieves method. On the other hand, the lowest values were given by
the mechanical shaker method in the laboratory. Furthermore, standard deviation and skewness did
not seem to be a ected by the sieving method which means that all the grainsize distribution was
shifted but the shape remained unchanged. The few samples that do not follow these patterns have a
higher percentage of shells. Finally and definitely, the small sieves should be rejected as a sieving
method aboard
Low molecular weight gelators (LMWGs) for ionic liquids: the role of hydrogen bonding and sterics in the formation of stable low molecular weight ionic liquid gels
3 sugar based low molecular weight gelators are shown to form ionic liquid gels with a diverse range of ionic liquids.</p
Leishmaniosis causing chronic diarrhoea in a dog
A 10-year-old, male, neutered Podenco Canario was presented for investigation of chronic mixed intestinal diarrhoea and weight loss. The dog was imported from Spain seven years earlier and had not subsequently travelled outside of the UK. Clinical investigations also revealed a lingual mass, right hindlimb lameness, splenomegaly, a non-regenerative anaemia and hyperglobulinaemia. Histopathology of endoscopic gastrointestinal biopsies revealed neutrophilic and histiocytic enteritis and colitis with high numbers of intracytoplasmic organisms suggestive of Leishmania. Similar organisms were identified on cytology from the spleen, bone marrow aspirate and lingual mass. Leishmania PCR was positive on a bone marrow aspirate. Clinical signs resolved with miltefosine and allopurinol treatment. This case describes an atypical presentation of leishmaniosis with chronic diarrhoea which presented for veterinary investigation and treatment, seven years after moving from a Leishmania endemic area to the UK
Implications of a Community-Based Learning Faculty Fellows Program to Facilitate Teaching and Learning in the Jesuit Tradition
The University of Scranton is one of the 28 Jesuit institutions of higher education located in the United States. Committed to community engagement and the development of Ignatian educators, a Community-Based Learning (CBL) Faculty Fellows Program was implemented academic year 2022-2023. The Ignatian Pedagogical Paradigm and the Engagement of Hope framework were used as models to develop, implement, and assess a CBL faculty development program. Program activities were designed to build faculty skills, capacities, and their identity as community-engaged practitioners. Lessons learned through program assessment on the impact on faculty’s transformation to Ignatian educators and their ability to imagine new possibilities and a hope-filled future through community-engaged work are discussed. The purpose of this paper is to contribute to the ongoing discussion on best practices to engage faculty in the use of Ignatian pedagogy at Jesuit universities using a CBL Faculty Fellows Program
The Telehealth Skills, Training, and Implementation Project: An evaluation protocol
External stabilization is reported to improve reliability of hand held dynamometry, yet this has not been tested in burns. We aimed to assess the reliability of dynamometry using an external system of stabilization in people with moderate burn injury and explore construct validity of strength assessment using dynamometry.
Participants were assessed on muscle and grip strength three times on each side. Assessment occurred three times per week for up to four weeks. Within session reliability was assessed using intraclass correlations calculated for within session data grouped prior to surgery, immediately after surgery and in the sub-acute phase of injury. Minimum detectable differences were also calculated. In the same timeframe categories, construct validity was explored using regression analysis incorporating burn severity and demographic characteristics.
Thirty-eight participants with total burn surface area 5 – 40% were recruited. Reliability was determined to be clinically applicable for the assessment method (intraclass correlation coefficient \u3e0.75) at all phases after injury. Muscle strength was associated with sex and burn location during injury and wound healing. Burn size in the immediate period after surgery and age in the sub-acute phase of injury were also associated with muscle strength assessment results.
Hand held dynamometry is a reliable assessment tool for evaluating within session muscle strength in the acute and sub-acute phase of injury in burns up to 40% total burn surface area. External stabilization may assist to eliminate reliability issues related to patient and assessor strength
Description of the Protocols for Randomized Controlled Trials on Cancer Drugs Conducted in Spain (1999-2003)
To describe the characteristics of randomized controlled clinical trials (RCT) on cancer drugs conducted in Spain between 1999 and 2003 based on their protocols. We conducted an observational retrospective cohort study to identify the protocols of RCTs on cancer drugs authorized by the Agencia Española del Medicamento y Productos Sanitarios (AEMPS) (Spanish Agency for Medicines and Medical Devices) during 1999-2003. A descriptive analysis was completed and the association between variables based on the study setting and sponsorship were assessed. We identified a total of 303 protocols, which included 176,835 potentially eligible patients. Three-quarter of the studies were internationally-based, 61.7% were phase III, and 76.2% were sponsored by pharmaceutical companies. The most frequently assessed outcomes were response rate (24.7%), overall survival (20.7%), and progression-free survival (14.5%). Of all protocols, 10.6% intended to include more than 1000 patients (mean: 2442, SD: 2724). Compared with their national counterparts, internationally-based studies were significantly larger (p<0.001) and were more likely to implement centralized randomization (p<0.001), blinding of the intervention (p<0.001), and survival as primary outcome (p<0.001). Additionally, most internationally-based studies were sponsored by pharmaceutical companies (p<0.01). In a high percentage of protocols, the available information was not explicit enough to assess the validity of each trial. Compared to other European countries, the proportion of Spanish cancer drugs protocols registered at (7%) was lower. RCTs on cancer drugs conducted in Spain between 1999 and 2003 were more likely to be promoted by pharmaceutical companies rather than by non-profit national groups. The former were more often part of international studies, which generally had better methodological quality than national ones. There are some worldwide on-going initiatives that aim to increase the transparency and quality of future research
Erythritol-enriched powder and oral biofilm regrowth on dental implants: an in vitro study.
BACKGROUND: Peri-implant mucositis and peri-implantitis are the main biological complications associated with dental implants. Since most authors agree that bacteria play a major etiological role, the main aims of this study were to determine if a formulation of erythritol and chlorhexidine applied with an air polishing system inhibits biofilm regrowth over dental implants and to compare the decontamination capacity of this therapy with that of mechanical removal by saline and gauze. MATERIAL AND METHODS: A multispecies biofilm (P. gingivalis, A. actinomycetemcomitans, F. nucleatum, A. naeslundii, V. parvula and S. oralis) was grown for 14 days on 52 dental implants in an artificial mouth. These implants were divided into three groups according to the applied treatment: 14 negative control (CON), 19 erythritol-chlorhexidine (ERY) and 19 gauze with saline (GAU) samples. Twelve dental implants from the ERY and GAU groups and 8 implants from the CON group were re-incubated for 7 additional days after treatment. The bacterial count was performed by quantitative polymerase chain reaction (qPCR) using propidium monoazide (PMA). A descriptive and bivariate analysis of the data was performed. RESULTS: The erythritol and chlorhexidine formulation significantly inhibited biofilm regrowth in comparison with the mechanical treatment (GAU), since a significant decrease in all the species was observed in the ERY group (except for Aggregatibacter actinomycetemcomitans). The antibiofilm and antibacterial capacity of the two active treatment groups (ERY and GAU) was similar for a 14 days multispecies in vitro biofilm, except for the lower count of A. naeslundii in the GAU group. CONCLUSIONS: The use of erythritol powder with chlorhexidine applied with an air polishing system reduces biofilm regrowth over dental implants when compared with mechanical removal by saline and gauze. This effect might be beneficial for patients included in peri-implant maintenance programs
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