La bioremédiation in situ des parcs conchylicoles par les éponges marines est-elle envisageable ?

The conservation of waters quality and the fight against pollution due to human activities havebecome global issues. Many biological contaminants and chemical pollutants are found in sea water, therefore in aquaculture products. This context fact sea professional are looking for solutions to preserve or even improve the quality of their waters. Among marine biodiversity, marine sponges filter 10 000 times their volume of water per day and retain 80 % of suspended particles such as organic matter, minerals, bacteria and viruses. In addition, sponges are therefore considered as bio-accumulators of metallic trace element such as lead, cadmium or copper. In collaboration with the Comité Régional de Conchyliculture de Bretagne Sud, REMEDBIO project proposes to exploite potential of marine sponges of the Brittany coast. One of the main priorities of this project is to reduce the impact of chemicals (heavy metals) and of biological contaminants (bacteria, viruses) on shellfish breeding. The marine sponges Hymeniacidon perlevis (Demospongiae) was chosen as the model for this study. Having demonstrated the feasibility of the culture of marine sponges on the foreshore, our work has shown, when tested in vitro, reduced contamination of oysters by two bacteria, Escherichia coli and Vibrio aestuarianus, and lead, a metal trace element, in the presence of sponges. The last phase of this work has been to enhance the results. The company LECOMER project began with the START'UBS contest (winner) proposed by the Université de Bretagne Sud in 2014. Thereafter, LECOMER was elected winner of the Innovation Awards of Morbihan in 2014.La préservation de la qualité des eaux marines et la lutte contre les pollutions liées à l'activité humaine sont devenues des enjeux mondiaux. De nombreux contaminants biologiques et polluants chimiques se retrouvent dans l’eau de mer, par conséquent dans les produits aquacoles. Ce contexte fait qu’aujourd’hui, les professionnels de la mer sont à la recherche de solutions pour préserver voire améliorer la qualité de leurs eaux. Au sein de notre biodiversité, les éponges marines sont des animaux capables de filtrer 10 000 fois leur volume en eau par jour et de retenir 80% des particules en suspension comme la matière organique, les minéraux, les bactéries et les virus. Par la même occasion, elles accumulent certains éléments traces métalliques comme le plomb, le cadmium ou le cuivre. En collaboration avec le Comité Régional de Conchyliculture de Bretagne Sud, le projet REMEDBIO dans lequel s’inscrit cette thèse se propose d'exploiter le potentiel de filtration des éponges marines du littoral breton. Les objectifs sont de contrôler le développement de bactéries pathogènes et de réduire la présence de polluants chimiques. L’éponge marine Hymeniacidon perlevis (Demospongiae) a été choisie comme modèle pour cette étude. Après avoir mis en évidence la faisabilité de la culture d’éponges marines sur l’estran, notre travail a montré, lors d’essais in vitro, une diminution de la contamination des huîtres par deux bactéries, Escherichia coli et Vibrio aestuarianus, et par le plomb, un élément trace métallique, en présence d’éponges. La dernière phase de ce travail a consisté à valoriser les résultats obtenus. Le projet d’entreprise LECOMER a débuté par le concours START’UBS (lauréat) proposé par l’Université de Bretagne Sud en 2014. Par la suite, LECOMER a été élu lauréat des Trophées de l’Innovation du Morbihan 2014

Is bioremediation of shellfish farms by marine sponges possible ?

La préservation de la qualité des eaux marines et la lutte contre les pollutions liées à l'activité humaine sont devenues des enjeux mondiaux. De nombreux contaminants biologiques et polluants chimiques se retrouvent dans l’eau de mer, par conséquent dans les produits aquacoles. Ce contexte fait qu’aujourd’hui, les professionnels de la mer sont à la recherche de solutions pour préserver voire améliorer la qualité de leurs eaux. Au sein de notre biodiversité, les éponges marines sont des animaux capables de filtrer 10 000 fois leur volume en eau par jour et de retenir 80% des particules en suspension comme la matière organique, les minéraux, les bactéries et les virus. Par la même occasion, elles accumulent certains éléments traces métalliques comme le plomb, le cadmium ou le cuivre. En collaboration avec le Comité Régional de Conchyliculture de Bretagne Sud, le projet REMEDBIO dans lequel s’inscrit cette thèse se propose d'exploiter le potentiel de filtration des éponges marines du littoral breton. Les objectifs sont de contrôler le développement de bactéries pathogènes et de réduire la présence de polluants chimiques. L’éponge marine Hymeniacidon perlevis (Demospongiae) a été choisie comme modèle pour cette étude. Après avoir mis en évidence la faisabilité de la culture d’éponges marines sur l’estran, notre travail a montré, lors d’essais in vitro, une diminution de la contamination des huîtres par deux bactéries, Escherichia coli et Vibrio aestuarianus, et par le plomb, un élément trace métallique, en présence d’éponges. La dernière phase de ce travail a consisté à valoriser les résultats obtenus. Le projet d’entreprise LECOMER a débuté par le concours START’UBS (lauréat) proposé par l’Université de Bretagne Sud en 2014. Par la suite, LECOMER a été élu lauréat des Trophées de l’Innovation du Morbihan 2014.The conservation of waters quality and the fight against pollution due to human activities havebecome global issues. Many biological contaminants and chemical pollutants are found in sea water, therefore in aquaculture products. This context fact sea professional are looking for solutions to preserve or even improve the quality of their waters. Among marine biodiversity, marine sponges filter 10 000 times their volume of water per day and retain 80 % of suspended particles such as organic matter, minerals, bacteria and viruses. In addition, sponges are therefore considered as bio-accumulators of metallic trace element such as lead, cadmium or copper. In collaboration with the Comité Régional de Conchyliculture de Bretagne Sud, REMEDBIO project proposes to exploite potential of marine sponges of the Brittany coast. One of the main priorities of this project is to reduce the impact of chemicals (heavy metals) and of biological contaminants (bacteria, viruses) on shellfish breeding. The marine sponges Hymeniacidon perlevis (Demospongiae) was chosen as the model for this study. Having demonstrated the feasibility of the culture of marine sponges on the foreshore, our work has shown, when tested in vitro, reduced contamination of oysters by two bacteria, Escherichia coli and Vibrio aestuarianus, and lead, a metal trace element, in the presence of sponges. The last phase of this work has been to enhance the results. The company LECOMER project began with the START'UBS contest (winner) proposed by the Université de Bretagne Sud in 2014. Thereafter, LECOMER was elected winner of the Innovation Awards of Morbihan in 2014

An eco-friendly strategy using flax/polylactide composite to tackle the marine invasive sponge Celtodoryx ciocalyptoides (Burton, 1935)

Summary: Discovered in the 1990s in the river of Etel (Morbihan, France), the marine invasive sponge Celtodoryx ciocalyptoides originating from the Chinese Yellow Sea is now well implanted on concrete pilings inside the Etel marina (Morbihan, France). Novel eco-friendly strategies are urgently needed in order to limit its adhesion on concrete and the risk of dispersal outside the marina. In this study, the anti-settlement and anti-attachment properties of flax/PLA, a biocomposite made of polylactide reinforced with flax fibres, were evaluated on sponge propagules’ behaviour. First, flax/PLA panels were immersed into the Etel marina for six years. The coverage onto PLA panels of marine invertebrates was estimated twice a year. In a second step, PLA panels were used as artificial support for invasive sponge transplants. In comparison, specimens were transplanted in mesh bags. Sponge weight increase was measured twice a year. Results indicated that the occurrence of the invasive sponge was delayed for two years on biocomposite in comparison with concrete. At the end of the six-year study, macrofouling by marine invertebrates did not exceed 70% of the surface of the panels and no C. ciocalyptoides specimens were observed. Once transplanted on PLA panels, sponge specimens were able to survive the first year without growing. After two years, none of the transplants survived while specimens in mesh bags increased their weight by 100%. These findings highlight the potential interest of biocomposite in the development of coastal and marine infrastructures. Keywords: Artificial substrate, Biocomposite, Celtodoryx ciocalyptoides, Marine invaders, Polylactid

Bioaccumulation of metallic trace elements and organic pollutants in marine sponges from the South Brittany Coast, France

International audienc

Successful Thrombectomy Improves Functional Outcome in Tandem Occlusions with a Large Ischemic Core

International audienceBackground: Emergent stenting in tandem occlusions and mechanical thrombectomy (MT) of acute ischemic stroke related to large vessel occlusion (LVO-AIS) with a large core are tested independently. We aim to assess the impact of reperfusion with MT in patients with LVO-AIS with a large core and a tandem occlusion and to compare the safety of reperfusion between large core with tandem and nontandem occlusions in current practice. Methods: We analyzed data of all consecutive patients included in the prospective Endovascular Treatment in Ischemic Stroke Registry in France between January 2015 and March 2023 who presented with a pretreatment ASPECTS (Alberta Stroke Program Early CT Score) of 0–5 and angiographically proven tandem occlusion. The primary end point was a favorable outcome defined by a modified Rankin Scale (mRS) score of 0–3 at 90 days. Results: Among 262 included patients with a tandem occlusion and ASPECTS 0–5, 203 patients (77.5%) had a successful reperfusion (modified Thrombolysis in Cerebral Infarction grade 2b-3). Reperfused patients had a favorable shift in the overall mRS score distribution (adjusted odds ratio [aOR], 1.57 [1.22–2.03]; P < 0.001), higher rates of mRS score 0–3 (aOR, 7.03 [2.60–19.01]; P < 0.001) and mRS score 0–2 at 90 days (aOR, 3.85 [1.39–10.68]; P = 0.009) compared with nonreperfused. There was a trend between the occurrence of successful reperfusion and a decreased rate of symptomatic intracranial hemorrhage (aOR, 0.5 [0.22–1.13]; P = 0.096). Similar safety outcomes were observed after large core reperfusion in tandem and nontandem occlusions. Conclusions: Successful reperfusion was associated with a higher rate of favorable outcome in large core LVO-AIS with a tandem occlusion, with a safety profile similar to nontandem occlusion