Analytische Modellierung des Zeitverhaltens und der Verlustleistung von CMOS-Gattern

In modernen CMOS-Technologien werden die Verzögerungszeit, die Ausgangsflankensteilheit und der Querstrom eines Gatters sowohl durch die Lastkapazität als auch durch die Steilheit des Eingangssignals beeinflusst. Die heute verwendeten Technologiebibliotheken beinhalten Tabellenmodelle mit 25 oder mehr Stützpunkten dieser Abhängigkeiten, woraus durch Interpolation die benötigten Zwischenwerte berechnet werden. Bisherige Versuche, analytische Modelle abzuleiten beruhten darauf, den Querstrom zu vernachlässigen oder Transistorströme als stückweise linear anzunähern. Der hier gezeigte Ansatz beruht auf einer näherungsweisen Lösung der Differentialgleichung, die aus den beiden Transistorströmen und einer Lastkapazität besteht und damit das Schaltverhalten eines Inverters beschreibt. Mit wenigen Technologieparametern können daraus für einen beliebig dimensionierten Inverter die für eine Timing- und Verlustleistungsanalyse notwendigen Größen berechnet werden. Das Modell erreicht bei einem Vergleich zu Referenzwerten aus SPICE Simulationen eine Genauigkeit von typischerweise 5%.</p><p style=&quot;line-height: 20px;&quot;>In modern CMOS-technologies the gate delay, output transition time and the short-circuit current depend on the capacitive load as well as on the input transition time. Today’s technology libraries use table models with 25 or more samples for these dependencies. Intermediate values have to be calculated through interpolation. Attempts to derive analytical models are based on neglecting the short-circuit current or approximating it by piecewise linear functions. The approach shown in this paper provides an approximate solution for the differential equation describing the dynamic behavor of an inverter circuit. It includes the influence of both transistor currents and a single load capacitance. The required values for timing and power analysis can be calculated with a small set of technology parameters for an arbitrary designed inverter. Compared to reference values extracted from SPICE simulations, the model achieves a typical precision of 5%

Recommended procedure for the IR spectroscopic determination of water in soda-lime-silica glass : Report of the International Commission on Glass (ICG) Technical Committee 14 "Gases in Glass"

The paper illustrates a procedure recommended by Technical Committee 14 (TC14 "Gases in Glass") of the International Commission on Glass (ICG) for the determination of the water content of soda-lime-silica glass by infrared transmittance spectroscopy, based on the two bands at 2.8 and 3.6 μm using as extincdon coefficients 70 and 150 l/(mol · cm), respectively As shown by the result of two intercomparisons, the agreement on the determined water concentration values can be quite satisfactory, within ±20 ppm, provided the procedure to evaluate the spectral curves is closely specified. The selected extinction coefficients are in reasonable agreement with recent evidence obtained using Nuclear Reaction Analysis

The influence of tDCS on perceived bouncing/streaming

Processing ambiguous situations is a constant challenge in everyday life and sensory input from different modalities needs to be integrated to form a coherent mental representation on the environment. The bouncing/streaming illusion can be studied to provide insights into the ambiguous perception and processing of multi-modal environments. In short, the likelihood of reporting bouncing rather than streaming impressions increases when a sound coincides with the moment of overlap between two moving disks. Neuroimaging studies revealed that the right posterior parietal cortex is crucial in cross-modal integration and is active during the bouncing/streaming illusion. Consequently, in the present study, we used transcranial direct current stimulation to stimulate this brain area. In the active stimulation conditions, a 9 cm2 electrode was positioned over the P4-EEG position and the 35 cm2 reference positioned over the left upper arm. The stimulation lasted 15 min. Each participant did the bouncing/streaming task three times: before, during and after anodal or sham stimulation. In a sample of N = 60 healthy, young adults, we found no influence of anodal tDCS. Bayesian analysis showed strong evidence against tDCS effects. There are two possible explanations for the finding that anodal tDCS over perceptual areas did not modulate multimodal integration. First, upregulation of multimodal integration is not possible using tDCS over the PPC as the integration process already functions at maximum capacity. Second, prefrontal decision-making areas may have overruled any modulated input from the PPC as it may not have matched their decision-making criterion and compensated for the modulation

Induced osteogenic differentiation of human smooth muscle cells as a model of vascular calcification

Vascular calcification is a severe pathological event in the manifestation of atherosclerosis. Pathogenic triggers mediating osteogenic differentiation of arterial smooth muscle cells (SMC) in humans remain insufficiently understood and are to a large extent investigated in animal models or cells derived thereof. Here, we describe an in vitro model based on SMC derived from healthy and diseased humans that allows to comprehensively investigate vascular calcification mechanisms. Comparing the impact of the commonly used SMC culture media VascuLife, DMEM, and M199, cells were characterised by immunofluorescence, flow cytometry, qPCR, and regarding their contractility and proliferative capacity. Irrespective of the arterial origin, the clinical background and the expansion medium used, all cells expressed typical molecular SMC marker while contractility varied between donors. Interestingly, the ability to induce an osteogenic differentiation strongly depended on the culture medium, with only SMC cultured in DMEM depositing calcified matrix upon osteogenic stimulation, which correlated with increased alkaline phosphatase activity, increased inorganic phosphate level and upregulation of osteogenic gene markers. Our optimized model is suitable for donor-oriented as well as broader screening of potential pathogenic mediators triggering vascular calcification. Translational studies aiming to identify and to evaluate therapeutic targets in a personalized fashion would be feasible

Resolving the L/T transition binary SDSS J2052-1609 AB

Binaries provide empirical key constraints for star formation theories, like the overall binary fraction, mass ratio distribution and the separation distribution. They play a crucial role to calibrate the output of theoretical models, like absolute magnitudes, colors and effective temperature depending on mass, metallicity and age. We present first results of our on-going high-resolution imaging survey of late type brown dwarfs. The survey aims at resolving tight brown dwarf binary systems to better constrain the T dwarf binary fraction. We intent to follow-up the individual binaries to determine orbital parameters. Using NACO at the VLT we performed AO-assisted near-infrared observations of SDSS J2052-1609. High-spatial resolution images of the T1 dwarf were obtained in H and Ks filters. We resolved SDSS J2052-1609 into a binary system with a separation of 0.101" \pm 0.001". Archival data from HST/NICMOS taken one year previous to our observations proves the components to be co-moving. Using the flux ratio between the components we infer J, H and Ks magnitudes for the resolved system. From the near-IR colors we estimate spectral types of T1 +1 -4 and T2.5 \pm 1 for component A and B, respectively. A first estimate of the total system mass yields Mtot > 78 Mjup, assuming a circular orbit.Comment: 5 pages, 3 figures, 3 tables, accepted for publication by A&

Terbium to Quantum Dot FRET Bioconjugates for Clinical Diagnostics: Influence of Human Plasma on Optical and Assembly Properties

Förster resonance energy transfer (FRET) from luminescent terbium complexes (LTC) as donors to semiconductor quantum dots (QDs) as acceptors allows extraordinary large FRET efficiencies due to the long Förster distances afforded. Moreover, time-gated detection permits an efficient suppression of autofluorescent background leading to sub-picomolar detection limits even within multiplexed detection formats. These characteristics make FRET-systems with LTC and QDs excellent candidates for clinical diagnostics. So far, such proofs of principle for highly sensitive multiplexed biosensing have only been performed under optimized buffer conditions and interactions between real-life clinical media such as human serum or plasma and LTC-QD-FRET-systems have not yet been taken into account. Here we present an extensive spectroscopic analysis of absorption, excitation and emission spectra along with the luminescence decay times of both the single components as well as the assembled FRET-systems in TRIS-buffer, TRIS-buffer with 2% bovine serum albumin, and fresh human plasma. Moreover, we evaluated homogeneous LTC-QD FRET assays in QD conjugates assembled with either the well-known, specific biotin-streptavidin biological interaction or, alternatively, the metal-affinity coordination of histidine to zinc. In the case of conjugates assembled with biotin-streptavidin no significant interference with the optical and binding properties occurs whereas the histidine-zinc system appears to be affected by human plasma

Concepts of health and well-being in managers: An organizational study

Global changes and new managerial challenges require new concepts of health and well-being in organizational contexts. In the South African context, health and well-being of managers have gained relevance in organizations and in management sciences. International organizations, in particular, attempt to address the increasing demand for health care and the delivery of health services to their managers. Careful and appropriate health management requires research to evaluate context-specific health concepts and strategies. The purpose and aim of this article is to assess managerial concepts on health and well-being that could be used by the organization to contribute to managerial well-being by implementing health promotion according to managerial needs. At the same time, this article contributes to salutogenetic health research that is very rare with regard to the South African organizational management research

Economic predictors of differences in interview faking between countries : economic inequality matters, not the state of economy

Many companies recruit employees from different parts of the globe, and faking behavior by potential employees is a ubiquitous phenomenon. It seems that applicants from some countries are more prone to faking compared to others, but the reasons for these differences are largely unexplored. This study relates country-level economic variables to faking behavior in hiring processes. In a cross-national study across 20 countries, participants (N = 3839) reported their faking behavior in their last job interview. This study used the random response technique (RRT) to ensure participants anonymity and to foster honest answers regarding faking behavior. Results indicate that general economic indicators (gross domestic product per capita [GDP] and unemployment rate) show negligible correlations with faking across the countries, whereas economic inequality is positively related to the extent of applicant faking to a substantial extent. These findings imply that people are sensitive to inequality within countries and that inequality relates to faking, because inequality might actuate other psychological processes (e.g., envy) which in turn increase the probability for unethical behavior in many forms