181 research outputs found
Robust fault decision : Contribution to Omni directional Mobile Robot
Fault diagnosis is crucial for ensuring the safe operation of complex engineering systems and avoiding the execution of an unsafe behaviour. This chapter deals with Robust Decision Making (RDM) for fault detection of electromechanical systems by combining the advantages of Bond Graph (BG) modeling and Fuzzy logic reasoning. A fault diagnosis method implemented in two stages is proposed. In the first stage, the residuals are deduced from the BG model allowing the building of a Fault Signature Matrix (FSM) according to the sensitivity of residuals to different parameters. In the second stage, the result of FSM and the robust residual thresholds are used by the fuzzy reasoning mechanism in order to evaluate a degree of detectability for each set of components. Finally, in order to make robust decision according to the detected fault component, an analysis is done between the output variables of the fuzzy system and components having the same signature in the FSM. The performance of the proposed fault diagnosis methodology is demonstrated through experimental data of an omni directional robot. - See more at: http://www.eurekaselect.com/102039/chapter/robust-fault-decision%3A-appl...
SBG for Health Monitoring of Fuel Cell System
To guarantee the safe operation of the Fuel Cell (FC) systems, it is necessary to use systematic techniques to detect and isolate faults for diagnosis purposes. The problematic for Fault Detection and Isolation (FDI) model-based of fuel cell consists in that such system is bad instrumented, its model is complex (because of coupling of multi-physical phenomena such as electrochemical, electrical, thermo fluidicâŠ) and the numerical values related to it are not always known. This is why qualitative model (based on existence or not of the links between variables and the relations) is well suited for fuel cell diagnosis. In this paper, we propose a new graphical model (named Signed Bond Graph) allowing to combine both qualitative and quantitative features for health monitoring (in terms of diagnosis and prognosis) of the fuel cell. The innovative interest of the presented paper is the use of only one representation for not only structural model but also diagnosis of faults which may affect the fuel cell. The developed theory is illustrated by an application to a Proton Exchange Membrane Fuel Cell (PEMFC).
Addressing decision making for remanufacturing operations and design-for-remanufacture
Remanufacturing is a process of returning a used product to at least original equipment manufacturer original performance specification from the customers' perspective and giving the resultant product a warranty that is at least equal to that of a newly manufactured equivalent. This paper explains the need to combine ecological concerns and economic growth and the significance of remanufacturing in this. Using the experience of an international aero-engine manufacturer it discusses the impact of the need for sustainable manufacturing on organisational business models. It explains some key decision-making issues that hinder remanufacturing and suggests effective solutions. It presents a peer-validated, high-level design guideline to assist decision-making in design in order to support remanufacturing. The design guide was developed in the UK through the analysis of selections of products during case studies and workshops involving remanufacturing and conventional manufacturing practitioners as well as academics. It is one of the initial stages in the development of a robust design for remanufacture guideline
Functional and Behavior Models for the Supervision of an Intelligent and Autonomous System
The graphical approaches often have different backgrounds and view a system or an algebraic model from different perspectives in order to facilitate the communication and the understanding. These graphical approaches satisfy the modeling needs and give a clear and easily understandable overview of the behavioral and functional models and make easier to see what the process is, which vulnerabilities and asset that are involved and how the system works. The main goal of this paper is to develop and implement a methodology which combines the functional analysis and the bond graph (BG) tool for intelligent and autonomous systems. As a result, a supervisory interface is obtained, given under a finite automaton, displaying to the operators the possibilities the system has to achieve or not, its objectives. Each operating mode, corresponding to a vertex of the automaton, is associated with a set of services from a functional point-of-view and is defined accurately by a behavioral BG model. Furthermore, the service availability (associated to the BG elements) and the conditions for switching from one mode to another one are analyzed by fault detection and isolation algorithms generated on the basis of the structural and causal properties of the BG tool. Moreover, when a fault is not completely isolable some results can nevertheless be expressed in terms of available or unavailable services
The association between real-life markers of phone use and cognitive performance, health-related quality of life and sleep
INTRODUCTION: The real-life short-term implications of electromagnetic fields (RF-EMF) on cognitive performance and health-related quality of life have not been well studied. The SPUTNIC study (Study Panel on Upcoming Technologies to study Non-Ionizing radiation and Cognition) aimed to investigate possible correlations between mobile phone radiation and human health, including cognition, health-related quality of life and sleep. METHODS: Adult participants tracked various daily markers of RF-EMF exposures (cordless calls, mobile calls, and mobile screen time 4 h prior to each assessment) as well as three health outcomes over ten study days: 1) cognitive performance, 2) health-related quality of life (HRQoL), and 3) sleep duration and quality. Cognitive performance was measured through six "game-like" tests, assessing verbal and visuo-spatial performance repeatedly. HRQoL was assessed as fatigue, mood and stress on a Likert-scale (1-10). Sleep duration and efficiency was measured using activity trackers. We fitted mixed models with random intercepts per participant on cognitive, HRQoL and sleep scores. Possible time-varying confounders were assessed at daily intervals by questionnaire and used for model adjustment. RESULTS: A total of 121 participants ultimately took part in the SPUTNIC study, including 63 from Besancon and 58 from Basel. Self-reported wireless phone use and screen time were sporadically associated with visuo-spatial and verbal cognitive performance, compatible with chance findings. We found a small but robust significant increase in stress 0.03 (0.00-0.06; on a 1-10 Likert-scale) in relation to a 10-min increase in mobile phone screen time. Sleep duration and quality were not associated with either cordless or mobile phone calls, or with screen time. DISCUSSION: The study did not find associations between short-term RF-EMF markers and cognitive performance, HRQoL, or sleep duration and quality. The most consistent finding was increased stress in relation to more screen time, but no association with cordless or mobile phone call time
Human Endogenous Retrovirus and Neuroinflammation in Chronic Inflammatory Demyelinating Polyradiculoneuropathy.
Human endogenous retroviruses HERV-W encode a pro-inflammatory protein, named MSRV-Env from its original identification in Multiple Sclerosis. Though not detected in various neurological controls, MSRV-Env was found in patients with chronic inflammatory demyelinating polyradiculoneuropathies (CIDPs). This study investigated the expression of MSRV in CIDP and evaluated relevant MSRV-Env pathogenic effects.
50 CIDP patients, 19 other neurological controls (ONDs) and 65 healthy blood donors (HBDs) were recruited from two different countries. MSRV-env and -pol transcripts, IL6 and CXCL10 levels were quantified from blood samples. MSRV-Env immunohistology was performed in distal sensory nerves from CIDP and neurological controls biopsies. MSRV-Env pathogenic effects and mode of action were assayed in cultured primary human Schwann cells (HSCs).
In both cohorts, MSRV-env and -pol transcripts, IL6 positivity prevalence and CXCL10 levels were significantly elevated in CIDP patients when compared to HBDs and ONDs (statistically significant in all comparisons). MSRV-Env protein was detected in Schwann cells in 5/7 CIDP biopsies. HSC exposed to or transfected with MSRV-env presented a strong increase of IL6 and CXCL10 transcripts and protein secretion. These pathogenic effects on HSC were inhibited by GNbAC1, a highly specific and neutralizing humanized monoclonal antibody targeting MSRV-Env.
The present study showed that MSRV-Env may trigger the release of critical immune mediators proposed as instrumental factors involved in the pathophysiology of CIDP. Significant MSRV-Env expression was detected in a significant proportion of patients with CIDP, in which it may play a role according to its presently observed effects on Schwann cells along with previously known effects on immune cells. Experimental results also suggest that a biomarker-driven therapeutic strategy targeting this protein with a neutralizing antibody such as GNbAC1 may offer new perspectives for treating CIDP patients with positive detection of MSRV-Env expression.
Geneuro-Innovation, France
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Reactor physics methods, models, and applications used to support the conceptual design of the Advanced Neutron Source
This report summarizes the neutronics analysis performed during 1991 and 1992 in support of characterization of the conceptual design of the Advanced Neutron Source (ANS). The methods used in the analysis, parametric studies, and key results supporting the design and safety evaluations of the conceptual design are presented. The analysis approach used during the conceptual design phase followed the same approach used in early ANS evaluations: (1) a strong reliance on Monte Carlo theory for beginning-of-cycle reactor performance calculations and (2) a reliance on few-group diffusion theory for reactor fuel cycle analysis and for evaluation of reactor performance at specific time steps over the fuel cycle. The Monte Carlo analysis was carried out using the MCNP continuous-energy code, and the few- group diffusion theory calculations were performed using the VENTURE and PDQ code systems. The MCNP code was used primarily for its capability to model the reflector components in realistic geometries as well as the inherent circumvention of cross-section processing requirements and use of energy-collapsed cross sections. The MCNP code was used for evaluations of reflector component reactivity effects and of heat loads in these components. The code was also used as a benchmark comparison against the diffusion-theory estimates of key reactor parameters such as region fluxes, control rod worths, reactivity coefficients, and material worths. The VENTURE and PDQ codes were used to provide independent evaluations of burnup effects, power distributions, and small perturbation worths. The performance and safety calculations performed over the subject time period are summarized, and key results are provided. The key results include flux and power distributions over the fuel cycle, silicon production rates, fuel burnup rates, component reactivities, control rod worths, component heat loads, shutdown reactivity margins, reactivity coefficients, and isotope production rates
Future of IR: Emerging Techniques, Looking to the FutureâŠand Learning from the Past
Innovation has been the cornerstone of interventional radiology since the early years of the founders, with a multitude of new therapeutic approaches developed over the last 50 years. What is the future holding for us? This article presents an overview of the in-coming developments that are catching on at this moment, particularly focusing on three items: the new applications of existing techniques, particularly embolotherapy and interventional oncology; the cutting-edge devices; the imaging technologies at the forefront of the image-guidance. Besides this, clinical vision and patient relation remain crucial for the future of the discipline
A lanthanum picrate complex of a 1,2-bisamide substituted calix[4]arene
The synthesis and structural characterization of a lanthanum picrate complex of the proximally-substituted calix[4]arene bisamide, 5,11,17,23-tetra-tert-butyl-25,26- bis(diethylcarbamoylmethoxy)-27,28-dihydroxycalix[4] arene (L), is reported. The complex is formulated as [La(L-H)(picrate)2]2.75CH2Cl2 and crystallises with two inequivalent metal complexes in the unit cell. The differing dispositions of the picrate anions in the two complexes suggest that intramolecular interactions between the aromatic rings of the picrate and calixarene are less significant than the forces involved in the crystal packing of the complexes
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