PERCEPTIONS OF MOOSE-HUMAN CONFLICTS IN AN URBAN ENVIRONMENT

Urban expansion produces obvious and deleterious ecological effects on wildlife habitat. Land development plans continue to be approved in Prince George, British Columbia, both within and on proximate land that is occupied by moose (Alces alces). We surveyed 100 residents of Prince George to determine how they perceive potential conflicts with moose and compared those perceptions with available local data. The majority (~75%) indicated that there were <50 moose-human encounterswithin Prince George in any given year; however, 222 moose-related reports occurred from April 2007-March 2008. This discrepancy indicates that the public probably underestimates both the presence of moose and moose-human conflicts in Prince George. We did not find that outdoor enthusiasts were more knowledgeable than others about managing moose-human conflicts, suggesting that broad public education and awareness programs are warranted. Understanding how to respond to moose and developing a “Moose Aware” program were two suggested strategies to reduce conflict. The vast majority of residents (92%) enjoy moose and want moose to remain part of the Prince George environment; only 9% were in favour of euthanasia or sharp-shooting to resolve conflicts. Because 40% indicated that the best option was leaving moose alone, managers will need to develop more effective strategies to minimize and manage moose-human conflicts

PERCEPTIONS OF MOOSE-HUMAN CONFLICTS IN AN URBAN ENVIRONMENT

Urban expansion produces obvious and deleterious ecological effects on wildlife habitat. Land development plans continue to be approved in Prince George, British Columbia, both within and on proximate land that is occupied by moose (Alces alces). We surveyed 100 residents of Prince George to determine how they perceive potential conflicts with moose and compared those perceptions with available local data. The majority (~75%) indicated that there were <50 moose-human encounterswithin Prince George in any given year; however, 222 moose-related reports occurred from April 2007-March 2008. This discrepancy indicates that the public probably underestimates both the presence of moose and moose-human conflicts in Prince George. We did not find that outdoor enthusiasts were more knowledgeable than others about managing moose-human conflicts, suggesting that broad public education and awareness programs are warranted. Understanding how to respond to moose and developing a “Moose Aware” program were two suggested strategies to reduce conflict. The vast majority of residents (92%) enjoy moose and want moose to remain part of the Prince George environment; only 9% were in favour of euthanasia or sharp-shooting to resolve conflicts. Because 40% indicated that the best option was leaving moose alone, managers will need to develop more effective strategies to minimize and manage moose-human conflicts

How COVID-19 has reshaped library services

ALIA Darling Downs is a regional professional community in its infancy. It exists to provide a platform for library practitioners in the regional Darling Downs area to network with other library professionals, stay up-to-date with library practices and attend professional development events. This group has members from a wide geographically dispersed area where the librarians are usually the only information professionals in their local communities. Our focus is to facilitate discussions and build our community. We aim to ensure the continuing involvement of Darling Downs library staff in matters pertaining to the profession. One of the biggest issues impacting the industry at the moment is COVID-19

Physiological roles for ecto-5’-nucleotidase (CD73)

Nucleotides and nucleosides influence nearly every aspect of physiology and pathophysiology. Extracellular nucleotides are metabolized through regulated phosphohydrolysis by a series of ecto-nucleotidases. The formation of extracellular adenosine from adenosine 5’-monophosphate is accomplished primarily through ecto-5’-nucleotidase (CD73), a glycosyl phosphatidylinositol-linked membrane protein found on the surface of a variety of cell types. Recent in vivo studies implicating CD73 in a number of tissue protective mechanisms have provided new insight into its regulation and function and have generated considerable interest. Here, we review contributions of CD73 to cell and tissue stress responses, with a particular emphasis on physiologic responses to regulated CD73 expression and function, as well as new findings utilizing Cd73-deficient animals

Dynamic purine signaling and metabolism during neutrophil–endothelial interactions

During episodes of hypoxia and inflammation, polymorphonuclear leukocytes (PMN) move into underlying tissues by initially passing between endothelial cells that line the inner surface of blood vessels (transendothelial migration, TEM). TEM creates the potential for disturbances in vascular barrier and concomitant loss of extravascular fluid and resultant edema. Recent studies have demonstrated a crucial role for nucleotide metabolism and nucleoside signaling during inflammation. These studies have implicated multiple adenine nucleotides as endogenous tissue protective mechanisms invivo. Here, we review the functional components of vascular barrier, identify strategies for increasing nucleotide generation and nucleoside signaling, and discuss potential therapeutic targets to regulate the vascular barrier during inflammation

International genome-wide meta-analysis identifies new primary biliary cirrhosis risk loci and targetable pathogenic pathways.

Primary biliary cirrhosis (PBC) is a classical autoimmune liver disease for which effective immunomodulatory therapy is lacking. Here we perform meta-analyses of discovery data sets from genome-wide association studies of European subjects (n=2,764 cases and 10,475 controls) followed by validation genotyping in an independent cohort (n=3,716 cases and 4,261 controls). We discover and validate six previously unknown risk loci for PBC (Pcombined<5 × 10(-8)) and used pathway analysis to identify JAK-STAT/IL12/IL27 signalling and cytokine-cytokine pathways, for which relevant therapies exist