145 research outputs found

    Green Coastal Zones: Nodes and Connectors as Strategy of Urban Regeneration

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    [EN] The landscape of Valencian Community is a resource with great cultural and heritage value. The system of Green Infrastructure ensures a continuous network of unbuilt areas with high environmental, cultural and visual value that also serves as ecological and functional connectors. The ERAM research project `Strategies for sustainable regeneration of tourist settlements on the Mediterranean coast¿ (2012¿14) identifies and analyzes the different types of coastal tourist towns of the Valencian region considering their needs for urban regeneration. It proposes strategies for prospective actions that can serve as a model for the regeneration of coastal tourist resorts. The determination of Green Coastal Zones (GCZ) aims to define their potential for urban regeneration in order to establish criteria for regional planning and urban design processes that will foster innovation in mature tourist destinations. The results show the potential of the 11 ERAM areas whose nodal connectivity and multifunctional landscape defines the framework for adaptive design strategies that may present alternative scenarios for touristic settlements.The ERAM research project ‘Strategies for sustainable regeneration of tourist settlements on the Mediterranean coast’ (2012–14) identifies and analyzes the different types of coastal tourist towns of the Valencian region considering their needs for urban regeneration.Tuset Davó, JJ. (2017). Green Coastal Zones: Nodes and Connectors as Strategy of Urban Regeneration. International Journal of Sustainable Development and Planning. 12(3):488-497. https://doi.org/10.2495/SDP-V12-N3-488-497S48849712

    Alicante Coastal Management for Sustainable Development

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    Human intervention on the coast has been intense, due to the source of wealth that the coastal areas represent, especially in the form of tourism, which has resulted in a rapid erosion of its beaches. This paper discusses the current state of beach management in the various competent public administrations on the Costa Blanca (SE Spanish-Mediterranean), in relation to urban development and regression on the waterfront. To this end, an analysis has been carried out of the responses to a survey of those responsible for managing each of the 19 coastal municipalities of the Alicante coast, covering 244 km of coastline, 91 beaches and their personnel. Also, an investigation has been conducted as to whether this management’s aim is to protect the coastline and maintain the flora and fauna or just to manage recreation as the main economic activity is tourism. The analysis shows that the beach is simply regarded as a product or service offered to the user thereof. However, local authorities have not detected problems, possibly for two reasons: they do not have sufficient knowledge and this is understandable, given their lack of responsibilities in this area. This causes many beaches to have a high occupancy rate and there is a shift of users towards natural beaches. The study gives us information about the complex administrative process in the coastal system that often proves ineffective on this narrow strip of land

    Thin-film silicon detectors for particle detection

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    Integrated particle sensors have been developed using thin-film on ASIC technology. For this purpose, hydrogenated amorphous silicon diodes, in various configurations, have been optimized for particle detection. These devices were first deposited on glass substrates to optimize the material properties and the dark current of very thick diodes (with thickness up to 50 μm). Corresponding diodes were later directly deposited on CMOS readout chips. These integrated particle sensors have been characterized using light pulse illumination and beta particle irradiation from 63Ni and 90Sr sources. Direct detection of single low- and high-energy beta particles have been demonstrated. The application of this new integrated particle sensor concept for medical imaging is also discussed

    The role of a firm's absorptive capacity and the technology transfer process in clusters: How effective are technology centres in low-tech clusters?

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    This paper analyses how the internal resources of small- and medium-sized enterprises determine access (learning processes) to technology centres (TCs) or industrial research institutes (innovation infrastructure) in traditional low-tech clusters. These interactions basically represent traded (market-based) transactions, which constitute important sources of knowledge in clusters. The paper addresses the role of TCs in low-tech clusters, and uses semi-structured interviews with 80 firms in a manufacturing cluster. The results point out that producer–user interactions are the most frequent; thus, the higher the sector knowledge-intensive base, the more likely the utilization of the available research infrastructure becomes. Conversely, the sectors with less knowledge-intensive structures, i.e. less absorptive capacity (AC), present weak linkages to TCs, as they frequently prefer to interact with suppliers, who act as transceivers of knowledge. Therefore, not all the firms in a cluster can fully exploit the available research infrastructure, and their AC moderates this engagement. In addition, the existence of TCs is not sufficient since the active role of a firm's search strategies to undertake interactions and conduct openness to available sources of knowledge is also needed. The study has implications for policymakers and academia

    The kinome of Phytophthora infestans reveals oomycete-specific innovations and links to other taxonomic groups

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    <p>Abstract</p> <p>Background</p> <p>Oomycetes are a large group of economically and ecologically important species. Its most notorious member is <it>Phytophthora infestans</it>, the cause of the devastating potato late blight disease. The life cycle of <it>P. infestans </it>involves hyphae which differentiate into spores used for dispersal and host infection. Protein phosphorylation likely plays crucial roles in these stages, and to help understand this we present here a genome-wide analysis of the protein kinases of <it>P. infestans </it>and several relatives. The study also provides new insight into kinase evolution since oomycetes are taxonomically distant from organisms with well-characterized kinomes.</p> <p>Results</p> <p>Bioinformatic searches of the genomes of <it>P. infestans</it>, <it>P. ramorum</it>, and <it>P. sojae </it>reveal they have similar kinomes, which for <it>P. infestans </it>contains 354 eukaryotic protein kinases (ePKs) and 18 atypical kinases (aPKs), equaling 2% of total genes. After refining gene models, most were classifiable into families seen in other eukaryotes. Some ePK families are nevertheless unusual, especially the tyrosine kinase-like (TKL) group which includes large oomycete-specific subfamilies. Also identified were two tyrosine kinases, which are rare in non-metazoans. Several ePKs bear accessory domains not identified previously on kinases, such as cyclin-dependent kinases with integral cyclin domains. Most ePKs lack accessory domains, implying that many are regulated transcriptionally. This was confirmed by mRNA expression-profiling studies that showed that two-thirds vary significantly between hyphae, sporangia, and zoospores. Comparisons to neighboring taxa (apicomplexans, ciliates, diatoms) revealed both clade-specific and conserved features, and multiple connections to plant kinases were observed. The kinome of <it>Hyaloperonospora arabidopsidis</it>, an oomycete with a simpler life cycle than <it>P. infestans</it>, was found to be one-third smaller. Some differences may be attributable to gene clustering, which facilitates subfamily expansion (or loss) through unequal crossing-over.</p> <p>Conclusion</p> <p>The large sizes of the <it>Phytophthora </it>kinomes imply that phosphorylation plays major roles in their life cycles. Their kinomes also include many novel ePKs, some specific to oomycetes or shared with neighboring groups. Little experimentation to date has addressed the biological functions of oomycete kinases, but this should be stimulated by the structural, evolutionary, and expression data presented here. This may lead to targets for disease control.</p

    The economic geography of the meso-global spaces: integrating multinationals and clusters at the local-global level

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    This is an author's accepted manuscript of an article published in: “European Planning Studies"; Volume 21, Issue 7, 2013; copyright Taylor & Francis; available online at: http://dx.doi.org/10.1080/09654313.2013.733853[EN] The local global phenomenon literature is fragmented between the fields of international business and economic geography (EG). In the case of the latter, the literature, produced within the global production networks (GPNs) and global value chain frameworks, does not address the central role of firms, especially multinationals which co-locate and connect territories along GPNs. This paper develops a cross-field conceptual integration in order to enrich the EG perspective, using qualitative research methodology to test the framework. The results have important implications for scholars and policymakers.We are very thankful to the “Ministry of Economics” funding ECO2010:17318 and “Generalitat Valenciana” for its support in visiting the London School of Economics and Political Science (BEST 2011 grants)Hervás Oliver, JL.; Boix Domenech, R. (2012). The economic geography of the meso-global spaces: integrating multinationals and clusters at the local-global level. European Planning Studies. 21(7):1064-1080. https://doi.org/10.1080/09654313.2013.733853S1064108021

    Weak phenotypic reversion of ivermectin resistance in a field resistant isolate of Haemonchus contortus by verapamil

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    Recent advances in anthelmintic resistant phenotype reversion by Pgp modulating drugs in ruminant nematodes indicate that this can be a useful tool to helminth control. The aim of the present study was to evaluate the efficacy of ivermectin (IVM) in combination with verapamil (VRP), in oil or water-based vehicle, against an IVM-resistant field isolate of Haemonchus contortus through a larval migration assay and experimental infection trial. In the in vitro assay was observed a phenotypic reversion of H. contortus resistance to ivermectin at a high concentration of VRP, increasing IVM efficacy from 53.1% to 94.3. In the in vivo trial, IVM + VRP demonstrated 36.02% efficacy compared to the 7.75% of IVM alone. The vehicle formulation showed no influence in efficacy. These are the first results demonstrating the effect of VRP as a partial IVM-resistance phenotype reverser in a field isolate of IVM-resistant H. contortus experimentally inoculated in sheep

    Leakage, entrepreneurship, and satisfaction in hospitality

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    This is an Accepted Manuscript of an article published by Taylor & Francis in The Service Industries Journal on 2013, available online:http://www.tandfonline.com/10.1080/02642069.2013.740464Tourism is a very important tool for economic development. However, its economic effects are mainly conditioned by the level of leakage. This work defines leakage, provides an original evaluation of the entrepreneurial environment in showing that it is the one with the lowest level of leakage, and creates a new framework. It also measures leakage in an innovative way using a quantitative approach. In addition, the paper explores and shows how leakage can affect critical business factors, such as customer and employee satisfaction. The empirical study uses structural equations and data from hotels in the Valencian Region (Spain) to show how important leakage is in making businesses more competitive. 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