A comparative study of the management of pediatric femoral shaft fractures treated conservatively with traction or spica casting

Background: Femoral shaft fractures, though not very common, are of major concern for orthopedic surgeons. the management for infants and older children is generally universal but the young patients still offer a management dilemma.Methods: We present a prospective study conducted at a tertiary care hospital in India of 37 children between 1 year and 6 years to compare the two conservative methods most commonly used i.e. spica casting and traction application.Results: We found that though both the methods are similar in the time for union, shortening was better controlled with traction and angulation with spica casting. The frequency of other complications was also comparable.Conclusions: Both the methods give acceptable results and given the feasibility of such procedures in developing countries, both may be recommended. However, the choice thus depends on the surgeon treating the patient keeping in mind the drawbacks and limitations of each

Losing Focus: Can It Be Useful in Robotic Laser Surgery?

This paper proposes a method to regulate the tissue temperature during laser surgery by robotically controlling the laser focus. Laser-tissue interactions are generally considered hard to control due to the inherent inhomogeneity of biological tissue, which can create significant variability in its thermal response to laser irradiation. In this study, we use methods from nonlinear control theory to synthesize a temperature controller capable of working on virtually any tissue type without any prior knowledge of its physical properties. The performance of the controller is evaluated in ex-vivo experiments.Comment: Provisionally Accepted at the Hamlyn Symposium on Medical Robotics 202

To study the efficacy of Mustadi Churna in Pandu Roga w.s.r. Haemoglobin percentage

Pandu is the disease which is described by all major classical texts of Ayurveda. As per Ayurvedic text in Pandu Roga the color of body look like polen grain of Ketki flower. Due to its similarity we can correlate Pandu Roga with modern science anaemia disease. Rasavaha and Raktavaha Strotasa are commonly involved in pathogenesis of Pandu Roga. Pandu if not treated properly can bring serious consequences to our health. Different Kalpas were described in Ayurved Samhitas for the treatment of Pandu Roga. In present study we use Mustadi Churna in the treatment of Pandu Roga and assess its efficacy

USE OF RECYCLED PLASTIC AS REPLACEMENT OF FINE AGGREGATE IN STRUCTURAL CONCRETE

Now a days disposal of dissipate plastic is one of the major green problem all above the world. The objective of this review paper is to examine the usefulness of using waste plastic as fine aggregate substitute in concrete mixtures. The compressive and tensile strength of a variety of concrete specimens were tested to establish how the amalgamation of recycled plastic as a replacement of fine aggregate would affect the expansion of strength in the mixes. In this reading plastic waste was mixed with cement concrete in a variety of scope such as 0%-15% and the M20 grade test specimen were casted to learning the behavior of plastic mixed concrete. All stages of plastic replacement show a perceptible diminish in compressive strength and tensile strength. https://journalnx.com/journal-article/2015071

Probiotics, their Health Benefits and Applications for Development of Human Health: A Review

Gastrointestinal microbial flora plays a major role in health of host. The person with the healthy digestive system is the indication of proper health. Probiotics bacteria are live nonpathogenic microorganism which has beneficial effects on host gastrointestinal tract which is mentioned in articles viz. Recent Advances in Pharmaceutical Approaches to Colon Specific Drug Delivery. Optimum population of probiotics bacteria are essential for the maintenance and effective functioning of the digestive system. Hence probiotics are the good therapeutic agents for the various abnormal conditions of gastrointestinal tract such as inflammatory bowel disease, chrohn’s disease, colon cancer etc. Probiotic micro biota also fights against pathogenic infections of GIT such as H. pylori infection by production of some antimicrobial chemical secretions such as bacteriocin. Recent studies and innovations and studies found that the probiotic bacteria are beneficial in the prevention and curative treatment of various disease and disorders like colorectal cancer, infection of urinary tract (UTI), allergic condition, cardiovascular disorders and depressive disorders. Probiotics are administered as nutraceutical products in the form of both conventional pharmaceutical dosage forms and traditional non-conventional food products, inclusion complexes with cyclodextrins effectively, sustained release tablets by solid dispersion technology etc. Probiotics are significantly gaining popularity due their wide application and safety. This paper presents the comprehensive review on the probiotics profile along with its some therapeutic applications, delivery approaches and current aspects.  Keywords: Probiotics, mechanisms, Health benefits, cardiovascular disorders, safety, colon targeted drug delivery system

In vitro absorption studies of acyclovir using natural permeation enhancers

Gastroretentive Delivery Systems are employed to improve the bioavailability of drugs which are absorbed through upper part of GIT, by increasing their retention time. Incorporation of permeability enhancers in the formulations of such drugs can further increase their bioavailability; however their use in the formulations is questionable due to the toxicity exhibited by them. Acyclovir is a class III drug having low oral bioavailability due to improper absorption. Mucoadhesive tablets of acyclovir containing natural permeation enhancers were prepared by direct compression and evaluated for mucoadhesion strength, in-vitro dissolution parameters and in-vitro absorption studies. The formulations containing Aloe vera extract showed increase in the mucoadhesion strength and retarded the drug release. The in-vitro absorption studies revealed that the formulations containing Aloe vera extract (Enhancement Ratio 1.94) and chausath prahar pippal (Enhancement Ratio 1.87) showed significant increase in the permeation of the drug. The studies led to the conclusion that by formulating mucoadhesive tablets of acyclovir containing natural permeation enhancers increased the permeability, thus proving to be the cheaper and easily available alternative to the other permeation enhancers.Colegio de Farmacéuticos de la Provincia de Buenos Aire

The Effects of Two Thick Film Deposition Methods on Tin Dioxide Gas Sensor Performance

This work demonstrates the variability in performance between SnO2 thick film gas sensors prepared using two types of film deposition methods. SnO2 powders were deposited on sensor platforms with and without the use of binders. Three commonly utilized binder recipes were investigated, and a new binder-less deposition procedure was developed and characterized. The binder recipes yielded sensors with poor film uniformity and poor structural integrity, compared to the binder-less deposition method. Sensor performance at a fixed operating temperature of 330 °C for the different film deposition methods was evaluated by exposure to 500 ppm of the target gas carbon monoxide. A consequence of the poor film structure, large variability and poor signal properties were observed with the sensors fabricated using binders. Specifically, the sensors created using the binder recipes yielded sensor responses that varied widely (e.g., S = 5 – 20), often with hysteresis in the sensor signal. Repeatable and high quality performance was observed for the sensors prepared using the binder-less dispersion-drop method with good sensor response upon exposure to 500 ppm CO (S = 4.0) at an operating temperature of 330 °C, low standard deviation to the sensor response (±0.35) and no signal hysteresis

Compositionally tunable ternary Bi2(Se1-xTex)3 and (Bi1-ySby)2Te3 thin films via low pressure chemical vapor deposition

The inherently rapid ligand substitution kinetics associated with the novel and chemically compatible precursors, [MCl3(EnBu2)3] (M = Sb, Bi; E = Se, Te), enable CVD growth of ternary Bi2(Se1−xTex)3 and (Bi1−ySby)2Te3 thin films with very good compositional, structural and morphological control, for the first time. X-ray diffraction data follow Vegard's law and Raman bands shift linearly with the atom substitutions, indicating very well-distributed solid solutions