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A Phase III open-label, randomized, multicenter study of imprime pgg in combination with cetuximab in patients with kras wild type metastatic colorectal cancer
Characterization and performance of the ASIC (CITIROC) front-end of the ASTRI camera
The Cherenkov Imaging Telescope Integrated Read Out Chip, CITIROC, is a chip adopted as the front-end of the camera at the focal plane of the imaging Cherenkov ASTRI dual-mirror small size telescope (ASTRI SST-2M) prototype. This paper presents the results of the measurements performed to characterize CITIROC tailored for the ASTRI SST-2M focal plane requirements. In particular, we investigated the trigger linearity and efficiency, as a function of the pulse amplitude. Moreover, we tested its response by performing a set of measurements using a silicon photomultiplier (SiPM) in dark conditions and under light pulse illumination. The CITIROC output signal is found to vary linearly as a function of the input pulse amplitude. Our results show that it is suitable for the ASTRI SST-2M camera. <P /
Civiltà della Campania. Anno I, n. 1 (dicembre 1974)
A.I, n. 1 (dicembre 1974): M. Parrilli, Editoriale, P. 3 ; R. Virtuoso, Civiltà della Campania, P. 3 ; G. Galasso, Fisionomìa storica della regione, P. 6 ; Natale in Campania, P. 11, R. Causa, Cinque secoli di Presepe di, P. 12 ; M. Stefanile, I presepi d’una volta di, P. 20 ; D. Rea, L’universo mangereccio del Presepe di, P. 28 ; M. Prisco, Il presepe in provincia di, P. 34 ; B. Gatta, Una storia che non fu, P. 42 ; A. Mozzillo, Stendhal a Napoli, P. 47 ; E. Perrin, Viaggio a Cava d’un abate francese, P. 52 ; A.P. Carbone, Ravello: Villa Rufolo un paradiso per tutti, 54 ; D. Fernandez, Lettera d’amore a Napoli, P. 60 ; A. Gatto, Un mazzetto di poesie con la mia mano, 54 ; M. Parrilli, Vocazione turistica e culturale del Salernitano, P. 60 ; E. Comito, Poesia di Casertantica, P. 64 ; A. Fratta, Majorca e le Sirene, P. 67 ; V. Ricciuti, De Sica addio, P. 72 ; M. Perrotta, Il motoscafo spazzino del mare di Capri, P. 76 ; F. Canessa, Ritorna l’« opera buffa », P. 78 ; P. Gargano, Archeologia in villa, P. 83 ; E. Corsi, Per un nuovo equilibrio alberghiero, P. 86 ; F. Garbaccio, Un termalismo per tutte le stagioni, P. 88; G. Blasi, Amalfi by night, P. 90 ; A. Scelzo, La maratona Paestum-Salerno, P. 91 ; Notiziario, P. 92 ; F. De Ciuceis, Segnalazioni bibliografiche, P. 95
Dental Health and Mortality in People With End-Stage Kidney Disease Treated With Hemodialysis: A Multinational Cohort Study
Background Dental disease is more extensive in adults with chronic kidney disease, but whether dental health and behaviors are associated with survival in the setting of hemodialysis is unknown. Study Design Prospective multinational cohort. Setting & Participants 4,205 adults treated with long-term hemodialysis, 2010 to 2012 (Oral Diseases in Hemodialysis [ORAL-D] Study). Predictors Dental health as assessed by a standardized dental examination using World Health Organization guidelines and personal oral care, including edentulousness; decayed, missing, and filled teeth index; teeth brushing and flossing; and dental health consultation. Outcomes All-cause and cardiovascular mortality at 12 months after dental assessment. Measurements Multivariable-adjusted Cox proportional hazards regression models fitted with shared frailty to account for clustering of mortality risk within countries. Results During a mean follow-up of 22.1 months, 942 deaths occurred, including 477 cardiovascular deaths. Edentulousness (adjusted HR, 1.29; 95% CI, 1.10-1.51) and decayed, missing, or filled teeth score ≥ 14 (adjusted HR, 1.70; 95% CI, 1.33-2.17) were associated with early all-cause mortality, while dental flossing, using mouthwash, brushing teeth daily, spending at least 2 minutes on oral hygiene daily, changing a toothbrush at least every 3 months, and visiting a dentist within the past 6 months (adjusted HRs of 0.52 [95% CI, 0.32-0.85], 0.79 [95% CI, 0.64-0.97], 0.76 [95% CI, 0.58-0.99], 0.84 [95% CI, 0.71-0.99], 0.79 [95% CI, 0.65-0.95], and 0.79 [95% CI, 0.65-0.96], respectively) were associated with better survival. Results for cardiovascular mortality were similar. Limitations Convenience sample of clinics. Conclusions In adults treated with hemodialysis, poorer dental health was associated with early death, whereas preventive dental health practices were associated with longer survival
The Third Fermi Large Area Telescope Catalog of Gamma-ray Pulsars
We present 294 pulsars found in GeV data from the Large Area Telescope (LAT)
on the Fermi Gamma-ray Space Telescope. Another 33 millisecond pulsars (MSPs)
discovered in deep radio searches of LAT sources will likely reveal pulsations
once phase-connected rotation ephemerides are achieved. A further dozen optical
and/or X-ray binary systems co-located with LAT sources also likely harbor
gamma-ray MSPs. This catalog thus reports roughly 340 gamma-ray pulsars and
candidates, 10% of all known pulsars, compared to known before Fermi.
Half of the gamma-ray pulsars are young. Of these, the half that are undetected
in radio have a broader Galactic latitude distribution than the young
radio-loud pulsars. The others are MSPs, with 6 undetected in radio. Overall,
>235 are bright enough above 50 MeV to fit the pulse profile, the energy
spectrum, or both. For the common two-peaked profiles, the gamma-ray peak
closest to the magnetic pole crossing generally has a softer spectrum. The
spectral energy distributions tend to narrow as the spindown power
decreases to its observed minimum near erg s, approaching the
shape for synchrotron radiation from monoenergetic electrons. We calculate
gamma-ray luminosities when distances are available. Our all-sky gamma-ray
sensitivity map is useful for population syntheses. The electronic catalog
version provides gamma-ray pulsar ephemerides, properties and fit results to
guide and be compared with modeling results.Comment: 142 pages. Accepted by the Astrophysical Journal Supplemen
Evidence for Circulation of Bovine Viral Diarrhoea Virus Type 2c in Ruminants in Southern Italy
Recently, bovine viral diarrhoea virus type 2c (BVDV-2c) was responsible for a severe outbreak in cattle in northern Europe. Here, we present the results of an epidemiological survey for pestiviruses in ruminants in southern Italy. Pooled serum samples were obtained from 997 bovine, 800 ovine, 431 caprine and eight bubaline farms, and pestiviral RNA was detected by molecular methods in 44 farms consisting of 16 cattle and one buffalo herds and of 21 sheep and six goat flocks. Twenty-nine and 15 farms were infected by BVDV-1 and BVDV-2 strains, respectively. BVDV-1 strains were recovered mainly from cattle and were heterogeneous, belonging to the subtypes 1b, 1u, 1e, 1g and 1h. In contrast, all BVDV-2 viruses but two were detected in sheep or goats and were characterized as BVDV-2c by sequence analysis of 5′UTR. These strains displayed high genetic identity to BVDV-2c circulating in cattle in northern Europe and were more distantly related to a BVDV-2c isolate recovered from a cattle herd in southern Italy more than 10 years before. The circulation of a BVDV-2c in small ruminants suggests the need for a continuous surveillance for the emergence of pestivirus-induced clinical signs in southern Italian farms
Testing the predictive power of realistic shell model calculations via lifetime measurement of the 11/2+ state in 131Sb
info:eu-repo/semantics/publishe
Are Red Lists really useful for plant conservation? The New Red List of the Italian Flora in the perspective of national conservation policies.
“The New Red List of the Italian Flora” includes all the Italian policy species and other species of known conservation concerns for a total of 400 taxa, 65% of which are threatened with extinction. The Red List is based on a huge georeferenced data-set useful for conservation purposes