670 research outputs found
Optical fibers to measure temperature vertical profile at sea
The paper is focus in the use the optical fiber to measure the temperature
in various heigh at the same time to get a temperature vertical variation. The
temperature measurements are puntual while the Bragg gratings located in the
fiber.Peer Reviewe
Blurred Lines Between Competition and Parasitism
Accurately describing the ecological relationships between species is more than mere semantics-doing so has profound practical and applied implications, not the least of which is that inaccurate descriptions can lead to fundamentally incorrect predicted outcomes of community composition and functioning. Accurate ecological classifications are particularly important in the context of global change, where species interactions can change rapidly following shifts in species composition. Here, we argue that many common ecological interactions-particularly competition and parasitism-can be easily confused and that we often lack empirical evidence for the full reciprocal interaction among species. To make our case and to propose a theoretical framework for addressing this problem, we use the interactions between lianas and trees, whose outcomes have myriad implications for the ecology and conservation of tropical forests (e.g., Schnitzer et al. 2015)
Left-right symmetric model with symmetry
We analyze the leptonic sector in the left-right symmetric model dressed with
a discrete symmetry which realizes, after weak spontaneous
breaking, a small broken \mu\lra\tau symmetry that is suggested to explain
observable neutrino oscillation data. \mu\lra\tau symmetry is broken at tree
level in the effective neutrino mass matrix due to the mass difference
in the diagonal Dirac mass
terms, whereas all lepton mixings arise from a Majorana mass matrix. In the
limit of a small breaking we determined , and the deviation from
the maximal value of , in terms of the light neutrino hierarchy
scale, , and a single free parameter of the model.Comment: 9 pages, 4 figures. Title changed and we have added one new section:
CP phase contribution. Minor corrections and references updated. Published
versio
On the semiclassical mass of -kinks
One-loop mass shifts to the classical masses of stable kinks arising in a
massive non-linear -sigma model are computed. Ultraviolet
divergences are controlled using the heat kernel/zeta function regularization
method. A comparison between the results achieved from exact and
high-temperature asymptotic heat traces is analyzed in depth.Comment: RevTex file, 15 pages, 2 figures. Version to appear in Journal of
Physics
Dynamic regulation of serum aryl hydrocarbon receptor agonists in MS
Objective: Several factors influence the clinical course of autoimmune inflammatory diseases
such as MS and inflammatory bowel disease. Only recently, the complex interaction between
the gut microbiome, dietary factors, and metabolism has started to be appreciated with regard
to its potential to modulate acute and chronic inflammation. One of the molecular sensors that
mediates the effects of these environmental signals on the immune response is the aryl hydrocarbon receptor (AHR), a ligand-activated transcription factor with key functions in immune cells.
Methods: In this study, we analyzed the levels of AHR agonists in serum samples from patients
with MS and healthy controls in a case-control study.
Results: We detected a global decrease of circulating AHR agonists in relapsing-remitting MS patients as compared to controls. However, during acute CNS inflammation in clinically isolated syndrome or active MS, we measured increased AHR agonistic activity. Moreover, AHR ligand levels
in patients with benign MS with relatively mild clinical impairment despite longstanding disease
were unaltered as compared to healthy controls.
Conclusions: Collectively, these data suggest that AHR agonists in serum are dynamically modulated during the course of MS. These findings may guide the development of biomarkers to monitor disease activity as well as the design of novel therapeutic interventions for MSInstituto de Salud Carlos III, Unión Europea PT13/0010/004
Golexanolone improves fatigue, motor incoordination and gait and memory in rats with bile duct ligation
\ua9 2023 The Authors. Liver International published by John Wiley & Sons Ltd.Background and Aims: Many patients with the chronic cholestatic liver disease primary biliary cholangitis (PBC) show fatigue and cognitive impairment that reduces their quality of life. Likewise, rats with bile duct ligation (BDL) are a model of cholestatic liver disease. Current PBC treatments do not improve symptomatic alterations such as fatigue or cognitive impairment and new, more effective treatments are therefore required. Golexanolone reduces the potentiation of GABAA receptors activation by neurosteroids. Golexanolone reduces peripheral inflammation and neuroinflammation and improves cognitive and motor function in rats with chronic hyperammonemia. The aims of the present study were to assess if golexanolone treatment improves fatigue and cognitive and motor function in cholestatic BDL rats and if this is associated with improvement of peripheral inflammation, neuroinflammation, and GABAergic neurotransmission in the cerebellum. Methods: Rats were subjected to bile duct ligation. One week after surgery, oral golexanolone was administered daily to BDL and sham-operated controls. Fatigue was analysed in the treadmill, motor coordination in the motorater, locomotor gait in the Catwalk, and short-term memory in the Y-maze. We also analysed peripheral inflammation, neuroinflammation, and GABAergic neurotransmission markers by immunohistochemistry and Western blot. Results: BDL induces fatigue, impairs memory and motor coordination, and alters locomotor gait in cholestatic rats. Golexanolone improves these alterations, and this was associated with improvement of peripheral inflammation, neuroinflammation, and GABAergic neurotransmission in the cerebellum. Conclusion: Golexanolone may have beneficial effects to treat fatigue, and motor and cognitive impairment in patients with the chronic cholestatic liver disease PBC
Ideal cardiovascular health, handgrip strength, and muscle mass among college students: The fuprecol adults study
The American Heart Association established the 2020 Strategic Impact Goals to define the concept of ideal cardiovascular health (CVH) and the metrics needed to monitor it across populations. The purpose of this study was to investigate the relationship between handgrip strength, muscle mass, and ideal CVH among Colombian college students. Data from 1,835 college students were analyzed (1,128 female). Muscular strength was estimated using a hand-held dynamometer and normalized to body mass (normalized grip strength [NGS]). The percentage of body fat was determined for bioelectrical impedance analysis using tetrapolar whole-body impedance. Ideal CVH was defined as meeting the ideal levels of 4 behaviors (smoking, body mass index, physical activity, and diet adherence) and 3 factors (total cholesterol, fasting glucose, and blood pressure). Higher levels of NGS and muscle mass (relative to body mass) were associated with a higher number of ideal CVH metrics in both sexes (p for trend less than 0.001). For the total ideal CVH metrics scored on a continuous scale from 0 (all 7 poor) to 7 (all 7 ideal), a 1-metric increase was associated with reduced odds of weak NGS (33 and 36%) and low-medium muscle mass (28 and 34%) mass in men and women, respectively (all p less than 0.001). This study indicates that in Colombian college students, both handgrip strength and muscle mass are positively associated with the ideal CVH metrics. To reduce the possible future public health burden of muscular weakness, health professionals need to encourage the public to optimize lifestyle-related risk factors during the young adult stage. © 2019 National Strength and Conditioning Association
Improving our own knowledge through analysing an episode from teachers’ practice – different focuses of analysis
Una de las formas esenciales para lograr una mejor comprensión del contenido del conocimiento
del profesor está ligada al análisis de su práctica. Esa práctica puede ser encarada de una forma
amplia que no se limite sólo a la práctica de clase. Por otro lado, una discusión y reflexión sobre
una misma situación de la práctica desde diferentes perspectivas teóricas y metodológicas puede
contribuir también a una mejor comprensión no solo de la práctica sino también de los
instrumentos metodológicos y teóricos en los que se sustenta el análisis. En esta comunicación
presentamos y discutimos parte del trabajo desarrollado en la reunión intermedia del grupo de
investigación sobre el conocimiento y desarrollo profesional del profesor de la SEIEM y cuyo foco
de atención fue la discusión de las potencialidades del análisis de un mismo episodio desde cinco
focos teóricos distintos.One of the core ways allowing obtain an ampler and deeper understanding on the content of
teachers’ knowledge concerns analysing teachers’ practices. Such practice can be perceived in a
broader way, not limited to classroom practice. On the other side, discussing and reflecting on the
same situation with different theoretical and methodological approaches seems to contribute also
for obtaining a deeper understanding not only on such practice but also on the used approaches for
such analysis. In this paper we present and discuss part of the work developed in the intermeeting
of the group research teachers’ knowledge and development of SEIEM concerning the potentialities
of analyzing one episode using five different theoretical approaches
Dissecting zero modes and bound states on BPS vortices in Ginzburg-Landau superconductors
Local pig breeds: Nutritional requirements, innovative practices and local feeding resources as challenges in project TREASURE
TREASURE is a research and innovation project of European Union’s Horizon 2020 programme which is devoted to traditional genetic resources in pig production with aim to improve their potentials for enhanced use. Studying and improving management of local pig breeds in their production systems is one of the challenges in which we address their performances and nutrition with special attention on locally available feeding resources and innovative practices aiming to improved welfare. For that purpose 15 experiments on 12 breeds were designed in the project, which are hereafter shortly presented. Their concepts and main objectives with some highlights on already available results are described. © 2017, University of Zagreb. All rights reserved
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