Implementing Emergency Bedside Backpacks in the NICU to Improve Patient Outcomes

Abstract Planning for a disaster, by implementing a unit specific disaster plan, has become an essential recommendation for Neonatal Intensive Care Units. Emergent situations have resulted from past natural disasters proving the need for additional planning when it comes to units with fragile populations. Research has shown instituting a specialized disaster plan, increases patient safety resulting in improved patient outcomes. This prospectus aims to implement emergency bedside backpacks as the first step in the development of a NICU specific disaster plan. These backpacks are meant to be an addition to the current hospital emergency plan, with the goal being to have similar success as other facilities that already have them in use. Our unit’s past experience with an evacuation demonstrated the need for additional disaster planning to improve our patient’s safety, staff coordination, and communication. Data was conducted via a SWOT analysis, and a fishbone diagram was created to determine what steps needed improvement. A Gantt chart was formulated to provide an anticipated time guideline, and process mapping was then completed to act as another planning guideline. A survey of the staff showed conflicting knowledge of what the current emergency protocol entails indicating a need for further disaster training. The prospected outcome is that this will be a successful, cost-effective project that will garner approval from all of the required hospital administration members, and become a standardized protocol

Adolescent Health Literacy: The Importance of Credible Sources for Online Health Information

Peer Reviewedhttp://deepblue.lib.umich.edu/bitstream/2027.42/89464/1/j.1746-1561.2011.00664.x.pd

Too Much of a Good Thing? Overexertion of Self-Control and Dietary Adherence in Individuals with Type 2 Diabetes

Objectives The resource model of self‐control posits that self‐control is a finite resource that can be depleted. Individuals with diabetes must continually restrict their diet, requiring self‐control. As a result, dietary adherence is difficult, and lapses are common. People with diabetes who overexert self‐control following a lapse may be especially likely to experience a subsequent relapse, as suggested by the resource model. This investigation used the resource model of self‐control to test whether overexertion of dietary self‐control following a lapse would be predictive of a subsequent relapse in dietary control. Design We tested this prediction in a daily diary study of 128 individuals with diabetes (Mage = 66.12). Methods Participants\u27 reports of their daily dietary adherence were used to define lapses in adherence, post‐lapse adherence, and relapses. Results Individuals who overexerted self‐control after a lapse were more likely to experience a subsequent relapse (OR = 3.276, p = .016) and to do so sooner (HR = 2.12, p = .023). Conclusions People with diabetes may seek to compensate for a lapse in adherence by overexerting self‐control, but doing so may deplete their self‐control and increase the risk of a future relapse

NASA Environmentally Responsible Aviation Hybrid Wing Body Flow-Through Nacelle Wind Tunnel CFD

Wind tunnel tests of a 5.75% scale model of the Boeing Hybrid Wing Body (HWB) configuration were conducted in the NASA Langley Research Center (LaRC) 14'x22' and NASA Ames Research Center (ARC) 40'x80' low speed wind tunnels as part of the NASA Environmentally Responsible Aviation (ERA) Project. Computational fluid dynamics (CFD) simulations of the flow-through nacelle (FTN) configuration of this model were performed before and after the testing. This paper presents a summary of the experimental and CFD results for the model in the cruise and landing configurations

ChIP-less analysis of chromatin states

BACKGROUND: Histone post-translational modifications (PTMs) are key epigenetic regulators in chromatin-based processes. Increasing evidence suggests that vast combinations of PTMs exist within chromatin histones. These complex patterns, rather than individual PTMs, are thought to define functional chromatin states. However, the ability to interrogate combinatorial histone PTM patterns at the nucleosome level has been limited by the lack of direct molecular tools. RESULTS: Here we demonstrate an efficient, quantitative, antibody-free, chromatin immunoprecipitation-less (ChIP-less) method for interrogating diverse epigenetic states. At the heart of the workflow are recombinant chromatin reader domains, which target distinct chromatin states with combinatorial PTM patterns. Utilizing a newly designed combinatorial histone peptide microarray, we showed that three reader domains (ATRX-ADD, ING2-PHD and AIRE-PHD) displayed greater specificity towards combinatorial PTM patterns than corresponding commercial histone antibodies. Such specific recognitions were employed to develop a chromatin reader-based affinity enrichment platform (matrix-assisted reader chromatin capture, or MARCC). We successfully applied the reader-based platform to capture unique chromatin states, which were quantitatively profiled by mass spectrometry to reveal interconnections between nucleosomal histone PTMs. Specifically, a highly enriched signature that harbored H3K4me0, H3K9me2/3, H3K79me0 and H4K20me2/3 within the same nucleosome was identified from chromatin enriched by ATRX-ADD. This newly reported PTM combination was enriched in heterochromatin, as revealed by the associated DNA. CONCLUSIONS: Our results suggest the broad utility of recombinant reader domains as an enrichment tool specific to combinatorial PTM patterns, which are difficult to probe directly by antibody-based approaches. The reader affinity platform is compatible with several downstream analyses to investigate the physical coexistence of nucleosomal PTM states associated with specific genomic loci. Collectively, the reader-based workflow will greatly facilitate our understanding of how distinct chromatin states and reader domains function in gene regulatory mechanisms

“Your Body Feels Better When You Drink Water”: Parent and School-Age Children’s Sugar- Sweetened Beverage Cognitions

Sugar-sweetened beverages (SSBs) are a leading source of added sugar in the American diet. Further, ingestion of added sugars from SSBs exceeds recommendations. Thus, interventions that effectively reduce SSB consumption are needed. Focus group discussions with parents (n = 37) and school-aged children between the ages of 6 and 11 years (n = 41) from Florida, New Jersey, and West Virginia were led by trained moderators using Social Cognitive Theory as a guide. Trends and themes that emerged from the content analysis of the focus group data indicated that both parents and children felt that limiting SSBs was important to health and weight control. However, parents and children reported consuming an average of 1.85 ± 2.38 SD and 2.13 ± 2.52 SD SSB servings/week, respectively. Parents and children were aware that parent behaviors influenced kids, but parents reported modeling healthy SSB behaviors was difficult. Busy schedules, including more frequent parties and events as children get older, were another barrier to limiting SSBs. Parents were most successful at limiting SSBs when they were not in the house. This qualitative research provides novel insights into parents’ and children’s cognitions (e.g., beliefs, attitudes), barriers, and facilitators related to SSB ingestion. Consideration of these insights during nutrition intervention development has the potential to improve intervention effectiveness in reducing SSB intake

Are prayer-based Interventions effective pain management options? A systematic review and meta-analysis of randomized controlled trials

This review examined the efects of private and communal participatory prayer on pain. Nine databases were searched. Six randomized controlled trials were included. For private prayer, medium to large efects emerged for 67% to 69% of betweengroup comparisons; participants in the prayer condition reported lower pain intensity (0.59<d<26.17; 4 studies) and higher pain tolerance (0.70<d<1.05; 1 study). Preto post-intervention comparisons yielded medium to large efects (0.76<d<1.67; 2 studies); pain intensity decreased. Although frm conclusions cannot be made because meta-analysis was based on only two studies, the analysis suggested prayer might reduce pain intensity (SMD=−2.63, 95% CI [−3.11, −2.14], I=0%). (PROSPERO: CRD42020221733)Fundação para a Ciência e Tecnologia - FCTinfo:eu-repo/semantics/publishedVersio

Francisella tularensis Transmission by Solid Organ Transplantation, 20171.

In July 2017, fever and sepsis developed in 3 recipients of solid organs (1 heart and 2 kidneys) from a common donor in the United States; 1 of the kidney recipients died. Tularemia was suspected only after blood cultures from the surviving kidney recipient grew Francisella species. The organ donor, a middle-aged man from the southwestern United States, had been hospitalized for acute alcohol withdrawal syndrome, pneumonia, and multiorgan failure. F. tularensis subsp. tularensis (clade A2) was cultured from archived spleen tissue from the donor and blood from both kidney recipients. Whole-genome multilocus sequence typing indicated that the isolated strains were indistinguishable. The heart recipient remained seronegative with negative blood cultures but had been receiving antimicrobial drugs for a medical device infection before transplant. Two lagomorph carcasses collected near the donor's residence were positive by PCR for F. tularensis subsp. tularensis (clade A2). This investigation documents F. tularensis transmission by solid organ transplantation