1,900 research outputs found
Distribution and genetic variability of Staphylinidae across a gradient of anthropogenically influenced insular landscapes
This paper describes the distribution and genetic variability of rove beetles (Coleoptera Staphylinidae) in anthropogenically influenced insular landscapes. The study was conducted in the Azores archipelago, characterized by high anthropogenic influence and landscape fragmentation. Collections were made in five islands, from eight habitats, along a gradient of anthropogenic influence. The species of Staphylinidae from the Azores collected for this study were widely distributed and showed low habitat fidelity. Rove beetle richness was associated with anthropogenic influence and habitat type, increasing from less to more anthropogenic impacted habitats. However, genetic diversity of profiled species (i.e. with three or more specimens per species/habitat) does not seem affected by anthropogenic influence in the different habitat types, isolation or landscape fragmentation. COI haplotypes were, as a rule, not exclusive to a given island or habitat. High level of genetic divergence and nucleotide saturation was found in closely related morphological designated species, demonstrating possible disparities between currently defined taxonomic units based on morphology and molecular phylogenies of Staphylinidae. This study found evidence of cryptic speciation in the Atheta fungi (Gravenhorst) species complex which had thus far remained undetected. Similar trends were found for Oligota parva Kraatz, Oxytelus sculptus Gravenhorst, Oligota pumilio Kiesenwetter. Previous studies with lower taxonomical resolution may have underestimated the biotic diversity reported in the Azores in comparison to other Macaronesian archipelagos.info:eu-repo/semantics/publishedVersio
Chiral spin textures creation and dynamics in a rectangular nanostructure
Controlled creation of stable chiral spin textures is required to use them as
an energy-efficient information carrier in spintronics. Here we have studied
the stable creation of isolated chiral spin texture (skyrmion and antiskyrmion)
and its pair through the magnetization reversal of a rectangular nanostructure
using spin-polarized currents. An isolated spin texture is created through a
negative current pulse. Dynamics of the stable spin texture are explored under
external magnetic fields, and the resonant frequencies are calculated. A stable
skyrmion pair is created using an asymmetric current pulse, and their
interaction is studied using the Thiele equation. The stability of isolated or
paired spin texture depends on the DMI strength, spin-polarized current
density, and pulse duration. In addition, the stability of the skyrmion pair
depends on their initial separation, and a threshold for the separation between
skyrmions of 78 nm is observed.Comment: 29 pages, 11 figures, 2 extra figure
Do vegetation patch spatial patterns disrupt the spatial organization of plant species?
Thelong-range spatial autocorrelationwasevaluated based on the dispersal abilities of the species.Among the 106 species evaluated, 39%of thewoody species, 17% of the forbs, and 12% of the grasses exhibited disrupted long-range spatial autocorrelation where patches were small. The species that are more vulnerable to the effects of fragmentation tended to be those that have restricted dispersal, such as those that have short-range ispersal (atelechoric), e.g., Phlomis purpurea, Cistus albidus, Teucrium pseudochamaepytis, Brachypodium retusum, and the ballistic species, Genista spartioides. Helianthemumalmeriense is another vulnerable species that has actively restricted dispersal (antitelechory), which is common in arid regions. Wind dispersers such as Launaea lanifera were less vulnerable to the effects of fragmentation. Long-distance dispersers whose persistence depends on facilitative interactions with other individuals, e.g., allogamous species such as Thymus hyemalis, Ballota hirsuta, and Anthyllis cytisoides, exhibit disrupted long-range spatial autocorrelation when patch size is reduce
Effect of Leaf Phosphorus and Potassium Concentration on Chlorophyll Meter Reading in Rice
Chlorophyll meter (SPAD) is a convenient tool to estimate leaf nitrogen (N) concentration of rice plants. There is no information on the effects of leaf phosphorus (P) and potassium (K) concentration on SP AD readings and on the relationship between SPAD values and leaf N concentration in the literature. In 1996 dry season, cv IR72 was grown at the International Rice Research Institute (IRRI) and the Philippine Rice Research Institute (PhilRice) under various N, P and K fertilizer combinations. SPAD measurements were made on the topmost fully expanded leaves at mid-tillering and panicle initiation. The leaves were then detached, dried and analyzed for N, P and K. The SPAD values were highly correlated with leaf N concentration (r = 0.93 to 0.96). Fertilizer-K application did not affect SP AD values, leaf N concentration, or the relationship between the two. Phosphorus deficiency reduced leaf N concentration at mid-tillering, but increased leaf N concentration at panicle initiation when the same amount of N was applied. The SPAD values were 1 to 2 units greater for zero-P plants than P-treated plants at a given leaf N concentration at mid-tillering. At panicle initiation, the relationship between SPAD values and leaf N concentration was not significantly affected by leaf P status. These results suggest that a different regression equation between SP AD values and leaf N concentration should be used to estimate leaf N concentration of P-deficient and P-sufficient rice leaves at vegetative stage using a SPAD
Dexamethasone as risk-factor for ICU-acquired respiratory tract infections in severe COVID-19
COVID-19; Critical care; DexamethasoneCOVID-19; Cuidados intensivos; DexametasonaCOVID-19; Cures crÃtiques; DexametasonaPurpose
Dexamethasone is the only drug that has consistently reduced mortality in patients with COVID-19, especially in patients needing oxygen or invasive mechanical ventilation. However, there is a growing concern about the relation of dexamethasone with the unprecedented rates of ICU-acquired respiratory tract infections (ICU-RTI) observed in patients with severe COVID-19.
Methods
This was a multicenter, prospective cohort study; conducted in ten countries in Latin America and Europe. We included patients older than 18 with confirmed SARS-CoV-2 requiring ICU admission. A multivariate logistic regression and propensity score matching (PSM) analysis was conducted to determine the relation between dexamethasone treatment and ICU-RTI.
Results
A total of 3777 patients were included. 2065 (54.7%) were treated with dexamethasone within the first 24 h of admission. After performing the PSM, patients treated with dexamethasone showed significantly higher proportions of VAP (282/1652 [17.1%] Vs. 218/1652 [13.2%], p = 0.014). Also, dexamethasone treatment was identified as an adjusted risk factor of ICU-RTI in the multivariate logistic regression model (OR 1.64; 95%CI: 1.37–1.97; p < 0.001).
Conclusion
Patients treated with dexamethasone for severe COVID-19 had a higher risk of developing ICU-acquired respiratory tract infections after adjusting for days of invasive mechanical ventilation and ICU length of stay, suggesting a cautious use of this treatment.This work was supported by Universidad de La Sabana (LFR) and the Spanish Society of Intensive and Critical Care Medicine and Coronary Units (SEMICYUC)
Sperm Hyperactivation and Capacitation Induced By Light Stimuli in Cryopreserved Semen
In mammals, such as rabbits, there are some factors involved in possible fertilization, from complex changes in the membrane of the sperm to obstruction or non-existent of vas deferens, which creates problems in the number and quality of sperm. In this work, we report the effects of rabbit sperm motility and capacitation of cryopreserved semen samples under light stimuli. The sperm velocities were correlated with the percentage of capacitated and non-capacitated sperm seen with a fluorescent dye. Consequently, we analyzed the specific correlations between irradiation times, supplied energy, and fertility parameters.
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COMVC-19: A Program to protect healthcare workers' mental health during the COVID-19 Pandemic. What we have learned
OBJECTIVE: In 2020, the COVID-19 pandemic brought a work and stress overload to healthcare workers, increasing their vulnerability to mental health impairments. In response, the authors created the COMVC-19 program. The program offered preventive actions and mental health treatment for the 22,000 workers of The Hospital das Clinicas da Faculdade de Medicina da Universidade de São Paulo (HCFMUSP). This paper aims to describe its implementation and share what we have learned from this experience.
METHODS: Workers were able to easily access the program through a 24/7 hotline. Additionally, a mobile phone app that screened for signs and symptoms of emotional distress and offered psychoeducation and/or referral to treatment was made available. Data from both these sources as well as any subsequent psychiatric evaluations were collected.
RESULTS: The first 20 weeks of our project revealed that most participants were female, and part of the nursing staff working directly with COVID-19 patients. The most frequently reported symptoms were: anxiety, depression and sleep disturbances. The most common diagnoses were Adjustment, Anxiety, and Mood disorders.
CONCLUSIONS: Implementing a mental health program in a multimodal intervention was feasible in a major quaternary public hospital. Our data also suggests that preventive actions should primarily be aimed at anxiety and depression symptoms, with a particular focus on the nursing staff.
 
Minimal lepton flavor violating realizations of minimal seesaw models
We study the implications of the global U(1)R symmetry present in minimal
lepton flavor violating implementations of the seesaw mechanism for neutrino
masses. In the context of minimal type I seesaw scenarios with a slightly
broken U(1)R, we show that, depending on the R-charge assignments, two classes
of generic models can be identified. Models where the right-handed neutrino
masses and the lepton number breaking scale are decoupled, and models where the
parameters that slightly break the U(1)R induce a suppression in the light
neutrino mass matrix. We show that within the first class of models,
contributions of right-handed neutrinos to charged lepton flavor violating
processes are severely suppressed. Within the second class of models we study
the charged lepton flavor violating phenomenology in detail, focusing on mu to
e gamma, mu to 3e and mu to e conversion in nuclei. We show that sizable
contributions to these processes are naturally obtained for right-handed
neutrino masses at the TeV scale. We then discuss the interplay with the
effects of the right-handed neutrino interactions on primordial B - L
asymmetries, finding that sizable right-handed neutrino contributions to
charged lepton flavor violating processes are incompatible with the requirement
of generating (or even preserving preexisting) B - L asymmetries consistent
with the observed baryon asymmetry of the Universe.Comment: 21 pages, 4 figures; version 2: Discussion on possible generic models
extended, typos corrected, references added. Version matches publication in
JHE
Development of peptide-based lineage-specific serology for chronic Chagas disease: geographical and clinical distribution of epitope recognition.
BACKGROUND: Chagas disease, caused by infection with the protozoan Trypanosoma cruzi, remains a serious public health issue in Latin America. Genetically diverse, the species is sub-divided into six lineages, known as TcI-TcVI, which have disparate geographical and ecological distributions. TcII, TcV, and TcVI are associated with severe human disease in the Southern Cone countries, whereas TcI is associated with cardiomyopathy north of the Amazon. T. cruzi persists as a chronic infection, with cardiac and/or gastrointestinal symptoms developing years or decades after initial infection. Identifying an individual's history of T. cruzi lineage infection directly by genotyping of the parasite is complicated by the low parasitaemia and sequestration in the host tissues. METHODOLOGY/PRINCIPAL FINDINGS: We have applied here serology against lineage-specific epitopes of the T. cruzi surface antigen TSSA, as an indirect approach to allow identification of infecting lineage. Chagasic sera from chronic patients from a range of endemic countries were tested by ELISA against synthetic peptides representing lineage-specific TSSA epitopes bound to avidin-coated ELISA plates via a biotin labelled polyethylene glycol-glycine spacer to increase rotation and ensure each amino acid side chain could freely interact with their antibodies. 79/113 (70%) of samples from Brazil, Bolivia, and Argentina recognised the TSSA epitope common to lineages TcII/TcV/TcVI. Comparison with clinical information showed that a higher proportion of Brazilian TSSApep-II/V/VI responders had ECG abnormalities than non-responders (38% vs 17%; p<0.0001). Among northern chagasic sera 4/20 (20%) from Ecuador reacted with this peptide; 1/12 Venezuelan and 1/34 Colombian samples reacted with TSSApep-IV. In addition, a proposed TcI-specific epitope, described elsewhere, was demonstrated here to be highly conserved across lineages and therefore not applicable to lineage-specific serology. CONCLUSIONS/SIGNIFICANCE: These results demonstrate the considerable potential for synthetic peptide serology to investigate the infection history of individuals, geographical and clinical associations of T. cruzi lineages
Stellar and Planetary Characterization of the Ross 128 Exoplanetary System from APOGEE Spectra
The first detailed chemical abundance analysis of the M dwarf (M4.0)
exoplanet-hosting star Ross 128 is presented here, based upon near-infrared
(1.5--1.7 \micron) high-resolution (22,500) spectra from the
SDSS-APOGEE survey. We determined precise atmospheric parameters =3231100K, log=4.960.11 dex and chemical abundances of eight
elements (C, O, Mg, Al, K, Ca, Ti, and Fe), finding Ross 128 to have near solar
metallicity ([Fe/H] = +0.030.09 dex). The derived results were obtained
via spectral synthesis (1-D LTE) adopting both MARCS and PHOENIX model
atmospheres; stellar parameters and chemical abundances derived from the
different adopted models do not show significant offsets. Mass-radius modeling
of Ross 128b indicate that it lies below the pure rock composition curve,
suggesting that it contains a mixture of rock and iron, with the relative
amounts of each set by the ratio of Fe/Mg. If Ross 128b formed with a sub-solar
Si/Mg ratio, and assuming the planet's composition matches that of the
host-star, it likely has a larger core size relative to the Earth. The derived
planetary parameters -- insolation flux (S=1.790.26) and
equilibrium temperature (=29410K) -- support previous findings
that Ross 128b is a temperate exoplanet in the inner edge of the habitable
zone.Comment: Accepted in ApJLetters, 3 figures, 2 tables, 12 page
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