The Spanish society of Parenteral and Enteral Nutrition (SENPE) and its relation with healthcare authorities

Está muy bien documentado en la literatura médica que la desnutrición es un problema común en todos los niveles de atención sanitaria, desde atención primaria a especializada y en centros de atención geriátrica. Este problema no se limita a países con pocos recursos económicos o con limitado desarrollo social y económico. También es un problema universal en Europa. La desnutrición aumenta las cifras de morbilidad, mortalidad, ingresos hospitalarios y duración de la estancia. Estas cifras más elevadas suponen lógicamente un aumento del uso de recursos sanitarios. A pesar de esto, el problema de la desnutrición a menudo puede pasar desapercibido y el paciente no recibir el tratamiento necesario. Este problema requiere la cooperación de múltiples agentes tales como los Gobiernos de los Estados, los profesionales de la salud y los mismos ciudadanos. El VIII Foro de Debate concluye con la necesidad de establecer un claro plan de actuación (a semejanza de la European Alliance for Health Nutrition) y la creación de una plataforma (coalición) que reúna las voces de asociaciones de profesionales sanitarios, instituciones, colegios profesionales, asociaciones de pacientes, industria y entidades aseguradoras. Los fines de esta plataforma consistirán en informar de la extensión del problema, identificar y potenciar líderes que transmitan los fines de esta iniciativa ante las autoridades autonómicas y nacionales, propuesta de soluciones y colaboración en su puesta en marcha y finalmente, evaluación/ control de las acciones desarrolladasIt has been well documented in medical literature that hyponutrition is a common issue at all healthcare levels, from primary to specialized health care, as well as geria - tric healthcare facilities. This problem is not limited to countries with scarce economic resources or limited social development; it is also a universal issue in Europe. Hyponutrition increases the rates of morbidity, mortality, hospital admissions, and hospital stay. These higher figures also represent a higher use of healthcare resources. In spite of this, hyponutrition may often go undetected and the patient may not receive the necessary treatment. This problem requires the cooperation of multiple agents such as the Governments, the healthcare professionals, and the citizens themselves. The VIII Discussion Forum concludes on the need to establish a clear-cut plant for action (similar to the European Alliance for Health Nutrition) and the creation of a platform (coalition) encompassing the voices of healthcare professionals associations, institutions, professional colleges, patients associations, the pharmaceutical companies, and insurance companies. The goals of this platform will be to inform about the extent of this issue, to identity and promote leaders that will convey the aims of this initiative to regional and national healthcare authorities, to present solutions and to collaborate in their implementation, and finally to assess/control the actions take

Use of Natural Microtalcs during the Virgin Olive Oil Production Process to Increase Its Content in Antioxidant Compounds

During the olive oil production process, certain olive varieties, such as ‘Hojiblanca’ and ‘Picual’, create pastes from which it is difficult to separate the oil, resulting in low extraction yields. To improve oil extraction, one alternative is the addition of natural microtalcs (NMT). In the present study, a NMT of great purity (CaCO3 concentration less than 6 wt.%) and small average particle size (φ ≤ 2.1 µm) was added in the malaxation stage on an industrial scale at two olive mills. In one of them and using ‘Hojiblanca’ olives, the performance of the high-purity NMT was compared with that of a traditional NMT, while in the other, the effect of its dosage in the quality of ‘Picual’ oils was assessed. The performance of the high-purity NMT was evaluated in terms of industrial oil yield, extractability index, quality parameters and oxidative stability of the resulting oils. The addition of the high-purity NMT not only increased the extraction yields but also improved the quality of the virgin olive oils, especially in relation to antioxidant compounds (tocopherols and phenolic compounds). Increases of 10.4% in phenolic compounds and of 21.5% in the tocopherols were found, thus enhancing the oxidative stability of the oils

Implementación de un sistema para la medición del flujo de tránsito y detección de embotellamientos en autopistas

En este trabajo implementamos un sistema para la medición de propiedades del ujo de tránsito para la detección de embotellamientos en autopistas. El sistema está basado en las técnicas de 'sustracción de fondo' y de 'seguimiento de características'. El sistema desarrollado permite: 1. cuanti car la fracción de llenado vehicular de distintas regiones de la autopista y 2. estimar la velocidad media del ujo de vehículos. Estudiamos la relación entre estas dos variables, y utilizando esta información proponemos un método para detectar automáticamente embotellamientos usando solo la fracción de llenado.Sociedad Argentina de Informática e Investigación Operativa (SADIO

Influencia del ciclo de cultivo y la conservación frigorífica en el color de la coliflor

La coliflor es un cultivo en aumento en la Región de Murcia, provocado principalmente por el incremento de su producción destinada a la exportación. Para mantener dicha cuota de exportación es necesaria la producción de una coliflor de gran calidad, requisito que cada vez más, aprecian los mercados nacionales. Esta calidad se basa fundamentalmente en su aspecto externo, donde el color de la pella es uno de los parámetros más importantes a tener en cuenta.Este trabajo ha sido financiando por el proyecto Séneca AGR/9/FS/9

Implementación de un sistema para la medición del flujo de tránsito y detección de embotellamientos en autopistas

En este trabajo implementamos un sistema para la medición de propiedades del ujo de tránsito para la detección de embotellamientos en autopistas. El sistema está basado en las técnicas de 'sustracción de fondo' y de 'seguimiento de características'. El sistema desarrollado permite: 1. cuanti car la fracción de llenado vehicular de distintas regiones de la autopista y 2. estimar la velocidad media del ujo de vehículos. Estudiamos la relación entre estas dos variables, y utilizando esta información proponemos un método para detectar automáticamente embotellamientos usando solo la fracción de llenado.Sociedad Argentina de Informática e Investigación Operativa (SADIO

Implementación de un sistema para la medición del flujo de tránsito y detección de embotellamientos en autopistas

En este trabajo implementamos un sistema para la medición de propiedades del ujo de tránsito para la detección de embotellamientos en autopistas. El sistema está basado en las técnicas de 'sustracción de fondo' y de 'seguimiento de características'. El sistema desarrollado permite: 1. cuanti car la fracción de llenado vehicular de distintas regiones de la autopista y 2. estimar la velocidad media del ujo de vehículos. Estudiamos la relación entre estas dos variables, y utilizando esta información proponemos un método para detectar automáticamente embotellamientos usando solo la fracción de llenado.Sociedad Argentina de Informática e Investigación Operativa (SADIO

First case of sterility associated with sex chromosomal abnormalities in a jenny

Chromosomal abnormalities are one of the main causes of genetic infertility in horses. Currently, their detection rate is rising due to the use of new diagnostic tools employing molecular markers linked to the sex chromosome pair. Despite genetic similarities, there are no previous reports of sterility associated with chromosomal abnormalities in the domestic donkey (Equus asinus). Hereby, we determined the presence of a chromosomal mosaicism in a female donkey with reproductive problems using molecular methodologies developed for horses. A two-and- a- half- year- old jenny characterized by morphological abnormalities of the reproductive tract was cytogenetically analysed using conventional and fluorescent techniques and a group of microsatellite markers (short tandem repeat, STR). At the same time, five ultrasound measures of the reproductive tract were taken and compared with eight contemporary jennies of the same breed. After slaughter, morphological examinations showed that the case study had a blind vaginal vestibule defining an empty pouch that covered the entrance of the cervical os. Histopathological studies demonstrated that this abnormal structure was compatible with a remnant hymen. Molecular markers, STR and fluorescent in situ hybridization determinations revealed that the animal was a 62, XX/61,X mosaic and, therefore, the first case of chromosomal abnormalities in the sex pair reported in donkeys.Instituto de Genética Veterinari

Cloud-based decision making in water distribution systems

The evolution of technologies of informatics and telecommunications has improved significantly the way water distribution systems can be managed. The use of quasi real-time information is becoming a desired standard in many water utilities. Nevertheless, tools for water distribution system analysis and for supporting decision making haveńt been integrated with the same speed. This research uses cloud computing capabilities for supporting analysis and decision making in water distribution systems. It includes the development of evolutionary algorithms ready to run in a cloud environment for searching the best possible decisions considering a set of objectives. The evaluation of solutions profits from the scalability of the cloud for making faster the solution search process.Montalvo Arango, I.; Izquierdo Sebastián, J.; Campbell, EOG.; Pérez García, R. (2014). Cloud-based decision making in water distribution systems. Procedia Engineering. 89:488-494. doi:10.1016/j.proeng.2014.11.241S4884948

Kidins220 deficiency causes ventriculomegaly via SNX27-retromer-dependent AQP4 degradation

Several psychiatric, neurologic and neurodegenerative disorders present increased brain ventricles volume, being hydrocephalus the disease with the major manifestation of ventriculomegaly caused by the accumulation of high amounts of cerebrospinal fluid (CSF). The molecules and pathomechanisms underlying cerebral ventricular enlargement are widely unknown. Kinase D interacting substrate of 220 kDa (KIDINS220) gene has been recently associated with schizophrenia and with a novel syndrome characterized by spastic paraplegia, intellectual disability, nystagmus and obesity (SINO syndrome), diseases frequently occurring with ventriculomegaly. Here we show that Kidins220, a transmembrane protein effector of various key neuronal signalling pathways, is a critical regulator of CSF homeostasis. We observe that both KIDINS220 and the water channel aquaporin-4 (AQP4) are markedly downregulated at the ventricular ependymal lining of idiopathic normal pressure hydrocephalus (iNPH) patients. We also find that Kidins220 deficient mice develop ventriculomegaly accompanied by water dyshomeostasis and loss of AQP4 in the brain ventricular ependymal layer and astrocytes. Kidins220 is a known cargo of the SNX27-retromer, a complex that redirects endocytosed plasma membrane proteins (cargos) back to the cell surface, thus avoiding their targeting to lysosomes for degradation. Mechanistically, we show that AQP4 is a novel cargo of the SNX27-retromer and that Kidins220 deficiency promotes a striking and unexpected downregulation of the SNX27-retromer that results in AQP4 lysosomal degradation. Accordingly, SNX27 silencing decreases AQP4 levels in wild-type astrocytes whereas SNX27 overexpression restores AQP4 content in Kidins220 deficient astrocytes. Together our data suggest that the KIDINS220-SNX27-retromer-AQP4 pathway is involved in human ventriculomegaly and open novel therapeutic perspectives