Índice de revelación de información contable

El objetivo de este trabajo será el de medir la cantidad de información revelada por las empresas no financieras del IBEX-35 en sus cuentas anuales. Para ello construiremos un índice que mida la cantidad de información facilitada por las empresas tanto obligatoria como voluntaria analizando principalmente la información incluida en la memoria y en el informe de gestión. Determinaremos además los factores explicativos de la revelación de información y comentaremos, mediante los resultados obtenidos, que tipos de empresas son las que proporcionan más información

Alfabetización tecnológica

Introduction: The social, economic and cultural environment is undergoing a transformation caused by computer technologies, becoming almost indispensable in our lives. However, the elderly can present problems of adaptation, triggering a lack of technological literacy that in the health field could have an impact on their quality of life. The objective is to observe how new technologies affect the elderly, and propose nursing interventions that favor their adaptation to this new era. Material and Methods: Articles published since 2009, from anywhere in the world, have been consulted free of charge, in Spanish and English. The databases consulted have been PubMed, Google Scholar, Mesh, ScienceDirect, Trip Database, IBECS and DeCS. Results: Currently, technologies are adapting and evolving differently around the world, assuming progress in all places. A positive effect has been observed regarding the relationship and communication between the elderly and their environment, being advisable to provide greater cognitive stimulation with respect to these. Discussion: Most of the evidence found points to the benefit that technology brings regarding the connection of the elderly with their social environment. In healthcare, telecare has proven to improve the quality of life of the elderly. Just as the electronic prescription helps with pharmacological adherence and provides comfort for chronic and / or multipathological patients, the telematic appointment reduces long waiting times. Conclusion: The technologies, associated with social isolation, telecare and electronic prescriptions, have a positive effect on the quality of life of the elderly population. Providing them with an exercise of their brain activity, greater selfesteem and comfort, solving their health problems from home without having to approach a health center.Introducción: El entorno social, económico y cultural está sufriendo una transformación causada por las tecnologías informáticas, convirtiéndose casi indispensables en nuestras vidas. Sin embargo, la edad anciana puede presentar problemas de adaptación, desencadenando una falta de alfabetización tecnológica que en el ámbito sanitario podría repercutir en su calidad de vida. El objetivo es observar cómo afectan las nuevas tecnologías a los ancianos, y proponer intervenciones enfermeras que favorezcan su adaptación a esta nueva era. Material y Métodos: Se han consultado artículos publicados a partir de 2009, de cualquier parte del mundo, de extensión completa gratuita, en español e inglés. Las bases de datos consultadas han sido PubMed, Google Académico, Mesh, ScienceDirect, Trip Database, IBECS y DeCS. Resultados: Actualmente las tecnologías están adaptándose y evolucionando de forma diferente por el mundo, suponiendo un avance en todos los lugares. Se ha observado un efecto positivo en cuanto a la relación y comunicación entre los ancianos y su entorno,siendo recomendable proporcionar una mayor estimulación cognitiva con respecto a estas. Discusión: La mayor parte de la evidencia encontrada apunta al beneficio que la tecnología aporta respecto a la conexión de los ancianos con su entorno social. En sanidad, la teleasistencia ha demostrado mejorar la calidad de vida de los ancianos. Así como la receta electrónica ayuda con la adherencia farmacológica y supone comodidad para pacientes crónicos y/o pluripatológicos, la cita telemática disminuye las largas esperas de consulta. Conclusión: Las tecnologías, asociadas al aislamiento social, teleasistencia y receta electrónica, tienen efecto positivo en la calidad de vida de la población anciana. Proporcionándoles una ejercitación de su actividad cerebral, una mayor autoestima y comodidad, solucionando sus problemas de salud desde casa sin tener que acercarse a un centro sanitario

Jardins per a la salut

Facultat de Farmàcia, Universitat de Barcelona. Ensenyament: Grau de Farmàcia. Assignatura: Botànica farmacèutica. Curs: 2014-2015. Coordinadors: Joan Simon, Cèsar Blanché i Maria Bosch.Els materials que aquí es presenten són el recull de les fitxes botàniques de 128 espècies presents en el Jardí Ferran Soldevila de l’Edifici Històric de la UB. Els treballs han estat realitzats manera individual per part dels estudiants dels grups M-3 i T-1 de l’assignatura Botànica Farmacèutica durant els mesos de febrer a maig del curs 2014-15 com a resultat final del Projecte d’Innovació Docent «Jardins per a la salut: aprenentatge servei a Botànica farmacèutica» (codi 2014PID-UB/054). Tots els treballs s’han dut a terme a través de la plataforma de GoogleDocs i han estat tutoritzats pels professors de l’assignatura. L’objectiu principal de l’activitat ha estat fomentar l’aprenentatge autònom i col·laboratiu en Botànica farmacèutica. També s’ha pretès motivar els estudiants a través del retorn de part del seu esforç a la societat a través d’una experiència d’Aprenentatge-Servei, deixant disponible finalment el treball dels estudiants per a poder ser consultable a través d’una Web pública amb la possibilitat de poder-ho fer in-situ en el propi jardí mitjançant codis QR amb un smartphone

A SARS-CoV-2-Human Protein-Protein Interaction Map Reveals Drug Targets and Potential Drug-Repurposing.

An outbreak of the novel coronavirus SARS-CoV-2, the causative agent of COVID-19 respiratory disease, has infected over 290,000 people since the end of 2019, killed over 12,000, and caused worldwide social and economic disruption1,2. There are currently no antiviral drugs with proven efficacy nor are there vaccines for its prevention. Unfortunately, the scientific community has little knowledge of the molecular details of SARS-CoV-2 infection. To illuminate this, we cloned, tagged and expressed 26 of the 29 viral proteins in human cells and identified the human proteins physically associated with each using affinity- purification mass spectrometry (AP-MS), which identified 332 high confidence SARS-CoV-2-human protein-protein interactions (PPIs). Among these, we identify 66 druggable human proteins or host factors targeted by 69 existing FDA-approved drugs, drugs in clinical trials and/or preclinical compounds, that we are currently evaluating for efficacy in live SARS-CoV-2 infection assays. The identification of host dependency factors mediating virus infection may provide key insights into effective molecular targets for developing broadly acting antiviral therapeutics against SARS-CoV-2 and other deadly coronavirus strains

A SARS-CoV-2-Human Protein-Protein Interaction Map Reveals Drug Targets and Potential Drug-Repurposing.

An outbreak of the novel coronavirus SARS-CoV-2, the causative agent of COVID-19 respiratory disease, has infected over 290,000 people since the end of 2019, killed over 12,000, and caused worldwide social and economic disruption1,2. There are currently no antiviral drugs with proven efficacy nor are there vaccines for its prevention. Unfortunately, the scientific community has little knowledge of the molecular details of SARS-CoV-2 infection. To illuminate this, we cloned, tagged and expressed 26 of the 29 viral proteins in human cells and identified the human proteins physically associated with each using affinity- purification mass spectrometry (AP-MS), which identified 332 high confidence SARS-CoV-2-human protein-protein interactions (PPIs). Among these, we identify 66 druggable human proteins or host factors targeted by 69 existing FDA-approved drugs, drugs in clinical trials and/or preclinical compounds, that we are currently evaluating for efficacy in live SARS-CoV-2 infection assays. The identification of host dependency factors mediating virus infection may provide key insights into effective molecular targets for developing broadly acting antiviral therapeutics against SARS-CoV-2 and other deadly coronavirus strains

Global attitudes in the management of acute appendicitis during COVID-19 pandemic: ACIE Appy Study

Background: Surgical strategies are being adapted to face the COVID-19 pandemic. Recommendations on the management of acute appendicitis have been based on expert opinion, but very little evidence is available. This study addressed that dearth with a snapshot of worldwide approaches to appendicitis. Methods: The Association of Italian Surgeons in Europe designed an online survey to assess the current attitude of surgeons globally regarding the management of patients with acute appendicitis during the pandemic. Questions were divided into baseline information, hospital organization and screening, personal protective equipment, management and surgical approach, and patient presentation before versus during the pandemic. Results: Of 744 answers, 709 (from 66 countries) were complete and were included in the analysis. Most hospitals were treating both patients with and those without COVID. There was variation in screening indications and modality used, with chest X-ray plus molecular testing (PCR) being the commonest (19\ub78 per cent). Conservative management of complicated and uncomplicated appendicitis was used by 6\ub76 and 2\ub74 per cent respectively before, but 23\ub77 and 5\ub73 per cent, during the pandemic (both P < 0\ub7001). One-third changed their approach from laparoscopic to open surgery owing to the popular (but evidence-lacking) advice from expert groups during the initial phase of the pandemic. No agreement on how to filter surgical smoke plume during laparoscopy was identified. There was an overall reduction in the number of patients admitted with appendicitis and one-third felt that patients who did present had more severe appendicitis than they usually observe. Conclusion: Conservative management of mild appendicitis has been possible during the pandemic. The fact that some surgeons switched to open appendicectomy may reflect the poor guidelines that emanated in the early phase of SARS-CoV-2