1,624 research outputs found

    The role of the Treaty of Waitangi in contemporary public law : does the Treaty have to be incorporated into municipal law to be of effect?

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    Recent work on Al-Cu-Mg based alloys with Cu:Mg atomic ratio close to unity is reviewed to clarify the mechanisms for age hardening. During the first stage of hardening a substantial exothermic heat evolution occurs whilst the microstructural change involves the formation of initially Cu-rich / Mg-rich clusters and later Cu-Mg co-clusters. The data show that the first stage of the age hardening is due to the formation of Cu-Mg co-clusters. The combined experimental methods show the second stage hardening is dominated by formation of S phase, which forms a dense precipitation at the peak hardness stage, whilst no significant amounts of other phases or zones are detected. S phase strengthens the alloy predominantly through the Orowan looping mechanism. These findings are incorporated into a multi-phase, multi-mechanism model for yield strength of Al-Cu-Mg based alloys

    Inflation driven by scalar field with non-minimal kinetic coupling with Higgs and quadratic potentials

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    We study a scalar field with non-minimal kinetic coupling to itself and to the curvature. The slow rolling conditions allowing an inflationary background have been found. The quadratic and Higgs type potentials have been considered, and the corresponding values for the scalar fields at the end of inflation allows to recover the connection with particle physics.Comment: 16 pages, to appear in JCA

    A Wideband Triple-Mode Differentially-Fed Microstrip Patch Antenna

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    © 2021 IEEE. This is the accepted manuscript version of an article which has been published in final form at https://dx.doi.org/10.1109/LAWP.2021.3074302A wideband differentially-fed microstrip patch antenna (MPA) with tripe-resonant modes is presented in this letter. The proposed triple-mode MPA is realized by combining two dual-mode MPAs (MPA-I and MPA-II) with different resonant frequency ratios. Firstly, the TM0,1 mode and TM0,1/2 mode of dual-mode MPA-I can be concurrently excited by adding a pair of coupling shorted patches beside the strip MPA. The ratio of f0,1/2/f0,1 can be easily adjusted by moving the shorting pins between the strip MPA and shorted patches. Secondly, by properly designing the dimensions of a conventional MPA, the TM0,1 and TM2,1 modes of dual-mode MPA-II are simultaneously excited. To further reduce the ratio of f2,1/f0,1, four slots are elaborately etched on the conventional MPA. Finally, by combining the two dual-mode MPAs, a triple-mode MPA with the frequency ratio of f0,1/2:f2,1:f0,1 = 1.2:1.1:1 is realized. To verify the design concept, a prototype of triple-mode MPA was fabricated and measured. Experimental results show that the proposed microstrip antenna achieves a wide bandwidth of 26.5%, a low cross-polarization of -23 dB, and high harmonic suppression.Peer reviewe

    Recurrence plot statistics and the effect of embedding

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    Recurrence plots provide a graphical representation of the recurrent patterns in a timeseries, the quantification of which is a relatively new field. Here we derive analytical expressions which relate the values of key statistics, notably determinism and entropy of line length distribution, to the correlation sum as a function of embedding dimension. These expressions are obtained by deriving the transformation which generates an embedded recurrence plot from an unembedded plot. A single unembedded recurrence plot thus provides the statistics of all possible embedded recurrence plots. If the correlation sum scales exponentially with embedding dimension, we show that these statistics are determined entirely by the exponent of the exponential. This explains the results of Iwanski and Bradley (Chaos 8 [1998] 861-871) who found that certain recurrence plot statistics are apparently invariant to embedding dimension for certain low-dimensional systems. We also examine the relationship between the mutual information content of two timeseries and the common recurrent structure seen in their recurrence plots. This allows time-localized contributions to mutual information to be visualized. This technique is demonstrated using geomagnetic index data; we show that the AU and AL geomagnetic indices share half their information, and find the timescale on which mutual features appear

    Large eddy simulation of a turbulent non-premixed propane-air reacting flame in a cylindrical combustor

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    Large Eddy Simulation (LES) is applied to investigate the turbulent non-premixed combustion flow, including species concentrations and temperature, in a cylindrical combustor. Gaseous propane (C3H8) is injected through a circular nozzle which is attached at the centre of the combustor inlet. Preheated air with a temperature of 773 K is supplied through the annulus surrounding of this fuel nozzle. In LES a spatial filtering is applied to the governing equations to separate the flow field into large-scale and small-scale eddies. The large-scale eddies which carry most of the turbulent energy are resolved explicitly, while the unresolved small-scale eddies are modelled using the Smagorinsky model with Cs = 0.1 as well as dynamically calibrated Cs. The filtered values of the species mass fraction, temperature and density, which are the functions of the mixture fraction (conserved scalar), are determined by integration over a beta probability density function (β-PDF). The computational results are compared with those of the experimental investigation conducted by Nishida and Mukohara. According to this experiment, the overall equivalence ratio of 0.6, which is calculated from the ratio of the air flow rate supplied to the combustion chamber to that of the stoichiometric reaction, is kept constant so that the turbulent combustion at the fuel nozzle exit starts under the fuel-rich conditions

    (Arg) 9 -SH2 superbinder: A novel promising anticancer therapy to melanoma by blocking phosphotyrosine signaling

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    Background: Melanoma is a malignant tumor with high misdiagnosis rate and poor prognosis. The bio-targeted therapy is a prevailing method in the treatment of melanoma; however, the accompanying drug resistance is inevitable. SH2 superbinder, a triple-mutant of the Src Homology 2 (SH2) domain, shows potent antitumor ability by replacing natural SH2-containing proteins and blocking multiple pY-based signaling pathways. Polyarginine (Arg) 9 , a powerful vector for intracellular delivery of large molecules, could transport therapeutic agents across cell membrane. The purpose of this study is to construct (Arg) 9 -SH2 superbinder and investigate its effects on melanoma cells, expecting to provide potential new approaches for anti-cancer therapy and overcoming the unavoidable drug resistance of single-targeted antitumor agents. Methods: (Arg) 9 and SH2 superbinder were fused to form (Arg) 9 -SH2 superbinder via genetic engineering. Pull down assay was performed to identify that (Arg) 9 -SH2 superbinder could capture a wide variety of pY proteins. Immunofluorescence was used to detect the efficiency of (Arg) 9 -SH2 superbinder entering cells. The proliferation ability was assessed by MTT and colony formation assay. In addition, wound healing and transwell assay were performed to evaluate migration of B16F10, A375 and A375/DDP cells. Moreover, apoptosis caused by (Arg) 9 -SH2 superbinder was analyzed by flow cytometry-based Annexin V/PI. Furthermore, western blot revealed that (Arg) 9 -SH2 superbinder influenced some pY-related signaling pathways. Finally, B16F10 xenograft model was established to confirm whether (Arg) 9 -SH2 superbinder could restrain the growth of tumor. Results: Our data showed that (Arg) 9 -SH2 superbinder had the ability to enter melanoma cells effectively and displayed strong affinities for various pY proteins. Furthermore, (Arg) 9 -SH2 superbinder could repress proliferation, migration and induce apoptosis of melanoma cells by regulating PI3K/AKT, MAPK/ERK and JAK/STAT signaling pathways. Importantly, (Arg) 9 -SH2 superbinder could significantly inhibit the growth of tumor in mice. Conclusions: (Arg) 9 -SH2 superbinder exhibited high affinities for pY proteins, which showed effective anticancer ability by replacing SH2-containing proteins and blocking diverse pY-based pathways. The remarkable ability of (Arg) 9 -SH2 superbinder to inhibit cancer cell proliferation and tumor growth might open the door to explore the SH2 superbinder as a therapeutic agent for cancer treatment

    Monte Carlo integration in Glauber model analysis of reactions of halo nuclei

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    Reaction and elastic differential cross sections are calculated for light nuclei in the framework of the Glauber theory. The optical phase-shift function is evaluated by Monte Carlo integration. This enables us to use the most accurate wave functions and calculate the phase-shift functions without approximation. Examples of proton nucleus (e.g. p-6^6He, p-6^6Li) and nucleus-nucleus (e.g. 6^6He12-^{12}C) scatterings illustrate the effectiveness of the method. This approach gives us a possibility of a more stringent analysis of the high-energy reactions of halo nuclei.Comment: 20 pages, 8 figure

    Theoretical investigations of a highly mismatched interface: the case of SiC/Si(001)

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    Using first principles, classical potentials, and elasticity theory, we investigated the structure of a semiconductor/semiconductor interface with a high lattice mismatch, SiC/Si(001). Among several tested possible configurations, a heterostructure with (i) a misfit dislocation network pinned at the interface and (ii) reconstructed dislocation cores with a carbon substoichiometry is found to be the most stable one. The importance of the slab approximation in first-principles calculations is discussed and estimated by combining classical potential techniques and elasticity theory. For the most stable configuration, an estimate of the interface energy is given. Finally, the electronic structure is investigated and discussed in relation with the dislocation array structure. Interface states, localized in the heterostructure gap and located on dislocation cores, are identified

    Star cluster formation and star formation: the role of environment and star-formation efficiencies

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    “The original publication is available at www.springerlink.com”. Copyright Springer. DOI: 10.1007/s10509-009-0088-5By analyzing global starburst properties in various kinds of starburst and post-starburst galaxies and relating them to the properties of the star cluster populations they form, I explore the conditions for the formation of massive, compact, long-lived star clusters. The aim is to determine whether the relative amount of star formation that goes into star cluster formation as opposed to field star formation, and into the formation of massive long-lived clusters in particular, is universal or scales with star-formation rate, burst strength, star-formation efficiency, galaxy or gas mass, and whether or not there are special conditions or some threshold for the formation of star clusters that merit to be called globular clusters a few billion years later.Peer reviewe
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