5 research outputs found
CryptoDex: A randomised, double-blind, placebo-controlled phase III trial of adjunctive dexamethasone in HIV-infected adults with cryptococcal meningitis: study protocol for a randomised control trial
Full text linkExplaining Preferences for Control Rights in Strategic Alliances: A Property Rights and Capabilities Perspective Approach
No full textParticipation in a Platform Ecosystem: Appropriability, Competition and Access to the Installed Base
No full textGroup B streptococcus and respiratory syncytial virus immunisation during pregnancy : a landscape analysis
Get PDFStreptococcus agalactiae or group B Streptococcus (GBS) and Respiratory Syncytial Virus (RSV) are leading causes of infant morbidity and mortality worldwide. There are currently no licensed vaccines for either disease, but vaccines for both are under development. Severe RSV disease can be prevented by passively administered antibody. The presence of maternal RSV-specific IgG antibody is associated with reduced prevalence and severity of RSV disease in the first few weeks of life, while maternal serotype-specific anti-capsular antibody is associated with protection against both early onset (EO) and late onset (LO) GBS disease. Vaccination in pregnancy offers an attractive method of protecting infants against both diseases. This structured review identifies what is known about immune protection against both diseases and identifies knowledge gaps in the immunobiology, with the aim of prioritizing research directions in maternal immunization.Medicine, Faculty ofOther UBCNon UBCPediatrics, Department ofReviewedFacultyGraduat
